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History Report on CCDS ID 35004 Interpretation | Date | Source | Comment | Data |
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CCDS: Made public |
02/26/2007 |
NCBI |
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CCDS Release: 3 |
CCDS: Retained |
04/30/2008 |
NCBI |
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CCDS Release: 5 |
CCDS: Retained |
07/28/2009 |
NCBI |
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CCDS Release: 6 |
CCDS: Retained |
03/30/2011 |
NCBI |
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CCDS Release: 8 |
CCDS: Public note |
04/22/2011 |
NCBI |
This CCDS ID represents the longest human BAG1 isoform, known as BAG-1L or p50, as described in the literature, including PMIDs 9396724, 9679980, 9747877 and 17662274. This isoform initiates translation at a non-AUG (CUG) start codon that is well-conserved and present in a strong Kozak signal context. Alternative translation initiation at downstream AUG start codons produces three additional isoforms with shorter N-termini, known as BAG-1M or p46, BAG-1S or p36 (also known as p33), and p29. The most abundant of the shorter isoforms, BAG-1S, is represented by CCDS 55301.1. Evidence in PMIDs 9747877 and 17662274 indicates that these isoforms have distinct subcellular distributions, which may contribute to the multifunctionality of the protein. |
CCDS version: 35004.1 |
CCDS: Retained |
08/11/2011 |
NCBI |
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CCDS Release: 9 |
CCDS: Retained |
09/19/2012 |
NCBI |
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CCDS Release: 11 |
CCDS: Retained |
03/21/2013 |
NCBI |
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CCDS Release: 12 |
CCDS: Retained |
08/30/2013 |
NCBI |
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CCDS Release: 14 |
CCDS: Retained |
11/21/2013 |
NCBI |
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CCDS Release: 15 |
CCDS: Retained |
06/20/2014 |
NCBI |
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CCDS Release: 17 |
CCDS: Retained |
04/03/2015 |
NCBI |
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CCDS Release: 18 |
CCDS: Retained |
08/11/2016 |
NCBI |
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CCDS Release: 20 |
CCDS: Review status |
10/03/2016 |
NCBI |
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by RefSeq, Havana and CCDS collaboration |
CCDS: Retained |
05/16/2018 |
NCBI |
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CCDS Release: 22 |
CCDS: Retained |
08/10/2022 |
NCBI |
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CCDS Release: 24 |
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