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Report for CCDS42293.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
42293.1 Public Homo sapiens 17 EVI2A 24 110 108 CCDS HistoryNCBI Gene:2123Re-query CCDS DB by CCDS ID:42293.1Re-query CCDS DB by GeneID:2123See the combined annotation on chromosome 17 in Sequence Viewer

Public Note for CCDS 42293.1
This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 4 aa shorter at the N-terminus. Both the longer and shorter N-termini have predicted signal peptides according to SignalP 3.0. There is no experimental evidence showing which start codon is preferentially used in vivo.

Public since: CCDS release 5, NCBI annotation release 36.3, Ensembl annotation release 47

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 42293.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000461237.5 ENSP00000418064.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000461237.5Link to Ensembl Protein Viewer:ENSP00000418064.1Re-query CCDS DB by Nucleotide ID:ENST00000461237Re-query CCDS DB by Protein ID:ENSP00000418064
Original member Current member EBI ENST00000462804.3 ENSP00000420557.3 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000462804.3Link to Ensembl Protein Viewer:ENSP00000420557.3Re-query CCDS DB by Nucleotide ID:ENST00000462804Re-query CCDS DB by Protein ID:ENSP00000420557
Original member Current member NCBI NM_014210.4 NP_055025.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_014210.4Link to Protein Sequence:NP_055025.2Re-query CCDS DB by Nucleotide ID:NM_014210Re-query CCDS DB by Protein ID:NP_055025Link to BLAST:NP_055025.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_055025.2 236 P22794-1 236 100% 0 0

Chromosomal Locations for CCDS 42293.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 17 (NC_000017.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17See the combined annotation on chromosome 17 in Sequence Viewer

Chromosome Start Stop Links
17 31318303 31319013 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 17Link to Ensembl Genome Browser on chromosome 17

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (711 nt):
ATGCCCACGGACATGGAACACACAGGACATTACCTACATCTTGCCTTTCTGATGACAACAGTTTTTTCTT
TG
TCTCCTGGAACAAAAGCAAACTATACCCGTCTGTGGGCTAACAGTACTTCTTCCTGGGATTCAGTTAT
T
CAAAACAAGACAGGCAGAAACCAAAATGAAAACATTAACACAAACCCTATAACTCCTGAAGTAGATTAT
AAA
GGTAATTCTACAAACATGCCTGAAACATCTCACATCGTAGCTTTAACTTCTAAATCTGAACAGGAGC
TT
TATATACCTTCTGTCGTCAGCAACAGTCCTTCAACAGTACAGAGCATTGAAAACACAAGCAAAAGTCA
T
GGTGAAATTTTCAAAAAGGATGTCTGTGCGGAAAACAACAACAACATGGCTATGCTAATTTGCTTAATT
ATA
ATTGCAGTGCTTTTTCTTATCTGTACCTTTCTATTTCTATCAACTGTGGTTTTGGCAAACAAAGTCT
CT
TCTCTCAGACGATCAAAACAAGTAGGCAAGCGTCAGCCTAGAAGCAATGGCGATTTTCTGGCAAGCGG
T
CTATGGCCCGCTGAATCAGACACTTGGAAAAGAACAAAACAGCTCACAGGACCCAACCTAGTGATGCAA
TCT
ACTGGAGTGCTCACAGCTACAAGGGAAAGAAAAGATGAAGAAGGAACTGAAAAACTTACTAACAAAC
AG
ATAGGTTAG


Translation (236 aa):
MPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDY
K
GNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLI
I
IAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQ
S
TGVLTATRERKDEEGTEKLTNKQIG




Links Key
 Links to:   History report
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 Genome Browser Links:   Ensembl Genome Browser
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