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Report for CCDS33656.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
33656.2 Public Homo sapiens 22 NDUFA6 24 110 108 CCDS HistoryNCBI Gene:4700Re-query CCDS DB by CCDS ID:33656.2Re-query CCDS DB by GeneID:4700See the combined annotation on chromosome 22 in Sequence Viewer

Public Note for CCDS 33656.1
This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates, cow and dog. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 26 aa shorter at the N-terminus. There is no experimental evidence showing which start codon is preferentially used in vivo.

Public since: CCDS release 3, NCBI annotation release 36.2, Ensembl annotation release 41

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 33656.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000498737.8 ENSP00000418842.3 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000498737.8Link to Ensembl Protein Viewer:ENSP00000418842.3Re-query CCDS DB by Nucleotide ID:ENST00000498737Re-query CCDS DB by Protein ID:ENSP00000418842
Original member Current member NCBI NM_002490.6 NP_002481.3 MANE Select Accepted alive Link to Nucleotide Sequence:NM_002490.6Link to Protein Sequence:NP_002481.3Re-query CCDS DB by Nucleotide ID:NM_002490Re-query CCDS DB by Protein ID:NP_002481Link to BLAST:NP_002481.3

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_002481.3 128 P56556 128 100% 0 0

Chromosomal Locations for CCDS 33656.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 22 (NC_000022.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 22Link to Ensembl Genome Browser on chromosome 22See the combined annotation on chromosome 22 in Sequence Viewer

Chromosome Start Stop Links
22 42086183 42086314 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 22Link to Ensembl Genome Browser on chromosome 22
22 42087060 42087175 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 22Link to Ensembl Genome Browser on chromosome 22
22 42090606 42090744 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 22Link to Ensembl Genome Browser on chromosome 22

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (387 nt):
ATGGCGGGGAGCGGCGTCCGCCAAGCTACTTCTACCGCCAGCACCTTCGTGAAGCCCATTTTCAGTCGGG
ACATGAACGAGGCCAAGCGGAGGGTGCGCGAGCTCTACCGCGCCTGGTATCGGGAGGTGCCGAACACTGT
GCACCAATTCCAGCTGGACATCACTGTGAAAATGGGACGGGATAAAGTCCGAGAAATGTTTATGAAGAAT
GCCCATGTCACAGACCCCAGGGTGGTTGATCTTCTGGTCATTAAGGGAAAGATCGAACTGGAAGAAACAA
TTAAAGTATGGAAGCAGCGGACACATGTTATGCGGTTCTTCCATGAAACAGAAGCGCCAAGGCCAAAGGA
TTTCCTATCCAAGTTCTATGTTGGCCACGATCCATGA

Translation (128 aa):
MAGSGVRQATSTASTFVKPIFSRDMNEAKRRVRELYRAWYREVPNTVHQFQLDITVKMGRDKVREMFMKN
AHVTDPRVVDLLVIKGKIELEETIKVWKQRTHVMRFFHETEAPRPKDFLSKFYVGHDP


Links Key
 Links to:   History report
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 Re-query CCDS DB by:   CCDS ID
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 Genome Browser Links:   Ensembl Genome Browser
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