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Genome Displays Related Resources Gene HomoloGene MANE RefSeq
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Report for CCDS42293.1 (current version)
CCDS |
Status |
Species |
Chrom. |
Gene |
CCDS Release |
NCBI Annotation Release |
Ensembl Annotation Release |
Links |
42293.1 |
Public |
Homo sapiens |
17 |
EVI2A |
24 |
110 |
108 |
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Public Note for CCDS 42293.1 |
This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 4 aa shorter at the N-terminus. Both the longer and shorter N-termini have predicted signal peptides according to SignalP 3.0. There is no experimental evidence showing which start codon is preferentially used in vivo. |
Public since: CCDS release 5, NCBI annotation release 36.3, Ensembl annotation release 47
Review status: Reviewed (by RefSeq, Havana and CCDS collaboration) Sequence IDs included in CCDS 42293.1
Original |
Current |
Source |
Nucleotide ID |
Protein ID |
MANE |
Status in CCDS |
Seq. Status |
Links |
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EBI |
ENST00000461237.5 |
ENSP00000418064.1 |
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Accepted |
alive |
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EBI |
ENST00000462804.3 |
ENSP00000420557.3 |
MANE Select |
Accepted |
alive |
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NCBI |
NM_014210.4 |
NP_055025.2 |
MANE Select |
Accepted |
alive |
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RefSeq |
Length |
Related UniProtKB/SwissProt |
Length |
Identity |
Gaps |
Mismatches |
NP_055025.2 |
236 |
P22794-1 |
236 |
100% |
0 |
0 |
Chromosomal Locations for CCDS 42293.1
Assembly GRCh38.p14 (GCF_000001405.40)
CCDS Sequence Data |
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Blue highlighting indicates alternating exons. | Red highlighting indicates amino acids encoded across a splice junction. | | Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair. |
Nucleotide Sequence (711 nt): ATGCCCACGGACATGGAACACACAGGACATTACCTACATCTTGCCTTTCTGATGACAACAGTTTTTTCTT TGTCTCCTGGAACAAAAGCAAACTATACCCGTCTGTGGGCTAACAGTACTTCTTCCTGGGATTCAGTTAT TCAAAACAAGACAGGCAGAAACCAAAATGAAAACATTAACACAAACCCTATAACTCCTGAAGTAGATTAT AAAGGTAATTCTACAAACATGCCTGAAACATCTCACATCGTAGCTTTAACTTCTAAATCTGAACAGGAGC TTTATATACCTTCTGTCGTCAGCAACAGTCCTTCAACAGTACAGAGCATTGAAAACACAAGCAAAAGTCA TGGTGAAATTTTCAAAAAGGATGTCTGTGCGGAAAACAACAACAACATGGCTATGCTAATTTGCTTAATT ATAATTGCAGTGCTTTTTCTTATCTGTACCTTTCTATTTCTATCAACTGTGGTTTTGGCAAACAAAGTCT CTTCTCTCAGACGATCAAAACAAGTAGGCAAGCGTCAGCCTAGAAGCAATGGCGATTTTCTGGCAAGCGG TCTATGGCCCGCTGAATCAGACACTTGGAAAAGAACAAAACAGCTCACAGGACCCAACCTAGTGATGCAA TCTACTGGAGTGCTCACAGCTACAAGGGAAAGAAAAGATGAAGAAGGAACTGAAAAACTTACTAACAAAC AGATAGGTTAG
Translation (236 aa): MPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDY KGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLI IIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQ STGVLTATRERKDEEGTEKLTNKQIG
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