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Report for CCDS58639.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
58639.1 Public Homo sapiens 19 OAZ1 24 110 108 CCDS HistoryNCBI Gene:4946Re-query CCDS DB by CCDS ID:58639.1Re-query CCDS DB by GeneID:4946See the combined annotation on chromosome 19 in Sequence Viewer

Public Note for CCDS 58639.1
The expression of the protein represented in this CCDS ID is auto-regulated by polyamine-enhanced translational frameshifting. During translation, a +1 frameshift occurs following codon 68, just preceding a termination codon, thereby enabling translation of the remaining portion of the protein (aa 69-228) in a different reading frame, as experimentally shown for the conserved rat ortholog (PMID:7813017).

Public since: CCDS release 11, NCBI annotation release 103, Ensembl annotation release 68

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
Ribosomal slippage (translational frameshift)

Sequence IDs included in CCDS 58639.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000602676.6 ENSP00000473381.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000602676.6Link to Ensembl Protein Viewer:ENSP00000473381.1Re-query CCDS DB by Nucleotide ID:ENST00000602676Re-query CCDS DB by Protein ID:ENSP00000473381
Original member Current member NCBI NM_004152.3 NP_004143.1 Accepted alive Link to Nucleotide Sequence:NM_004152.3Link to Protein Sequence:NP_004143.1Re-query CCDS DB by Nucleotide ID:NM_004152Re-query CCDS DB by Protein ID:NP_004143Link to BLAST:NP_004143.1

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_004143.1 228 P54368-1 228 100% 0 0

Chromosomal Locations for CCDS 58639.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 19 (NC_000019.10)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 19Link to Ensembl Genome Browser on chromosome 19See the combined annotation on chromosome 19 in Sequence Viewer

Chromosome Start Stop Links
19 2269599 2269744 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 19Link to Ensembl Genome Browser on chromosome 19
19 2271385 2271442 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 19Link to Ensembl Genome Browser on chromosome 19
19 2271444 2271530 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 19Link to Ensembl Genome Browser on chromosome 19
19 2271782 2271954 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 19Link to Ensembl Genome Browser on chromosome 19
19 2272735 2272820 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 19Link to Ensembl Genome Browser on chromosome 19
19 2272972 2273108 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 19Link to Ensembl Genome Browser on chromosome 19

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (687 nt):
ATGGTGAAATCCTCCCTGCAGCGGATCCTCAATAGCCACTGCTTCGCCAGAGAGAAGGAAGGGGATAAAC
CCAGCGCCACCATCCACGCCAGCCGCACCATGCCGCTCCTAAGCCTGCACAGCCGCGGCGGCAGCAGCAG
TGAGAGTTCCAGGGTCTCCCTCCACTGCTGTAGTAACCCGGGTCCGGGGCCTCGGTGGTGCTCCGATGCC
CCTCACCCACCCCTGAAGATCCCAGGTGGGCGAGGGAATAGTCAGAGGGATCACAATCTTTCAGCTAACT
TATTCTACTCCGATGATCGGCTGAATGTAACAGAGGAACTAACGTCCAACGACAAGACGAGGATTCTCAA
CGTCCAGTCCAGGCTCACAGACGCCAAACGCATTAACTGGCGAACAGTGCTGAGTGGCGGCAGCCTCTAC
ATCGAGATCCCGGGCGGCGCGCTGCCCGAGGGGAGCAAGGACAGCTTTGCAGTTCTCCTGGAGTTCGCTG
AGGAGCAGCTGCGAGCCGACCATGTCTTCATTTGCTTCCACAAGAACCGCGAGGACAGAGCCGCCTTGCT
CCGAACCTTCAGCTTTTTGGGCTTTGAGATTGTGAGACCGGGGCATCCCCTTGTCCCCAAGAGACCCGAC
GCTTGCTTCATGGCCTACACGTTCGAGAGAGAGTCTTCGGGAGAGGAGGAGGAGTAG

Translation (228 aa):
MVKSSLQRILNSHCFAREKEGDKPSATIHASRTMPLLSLHSRGGSSSESSRVSLHCCSNPGPGPRWCSDA
PHPPLKIPGGRGNSQRDHNLSANLFYSDDRLNVTEELTSNDKTRILNVQSRLTDAKRINWRTVLSGGSLY
IEIPGGALPEGSKDSFAVLLEFAEEQLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPD
ACFMAYTFERESSGEEEE


Links Key
 Links to:   History report
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 Re-query CCDS DB by:   CCDS ID
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 Genome Browser Links:   Ensembl Genome Browser
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