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Report for CCDS6396.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
6396.1 Public Homo sapiens 8 LY6H 24 110 108 CCDS HistoryNCBI Gene:4062Re-query CCDS DB by CCDS ID:6396.1Re-query CCDS DB by GeneID:4062See the combined annotation on chromosome 8 in Sequence Viewer

Public Note for CCDS 6396.1
This CCDS represents the shorter LY6H isoform. NM_002347.4 is based on an alternative 5' end, as found in the ESTs DB471677.1, BP347868.1 and EB385547.1. Other alternative 5' ends exist, as in AK314139.1, BC028894.1, AB012293.1 and BC030192.1, and these contain an upstream in-frame translation start codon which results in an isoform that is 21 aa longer at the N-terminus. The upstream start codon has a weaker Kozak signal than the downstream start codon, so these variants may also produce the shorter isoform, as suggested in PMID:9799603.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 6396.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000430474.6 ENSP00000409899.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000430474.6Link to Ensembl Protein Viewer:ENSP00000409899.2Re-query CCDS DB by Nucleotide ID:ENST00000430474Re-query CCDS DB by Protein ID:ENSP00000409899
Original member Current member EBI ENST00000615409.1 ENSP00000480084.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000615409.1Link to Ensembl Protein Viewer:ENSP00000480084.1Re-query CCDS DB by Nucleotide ID:ENST00000615409Re-query CCDS DB by Protein ID:ENSP00000480084
Original member Current member NCBI NM_002347.5 NP_002338.3 Accepted alive Link to Nucleotide Sequence:NM_002347.5Link to Protein Sequence:NP_002338.3Re-query CCDS DB by Nucleotide ID:NM_002347Re-query CCDS DB by Protein ID:NP_002338Link to BLAST:NP_002338.3

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_002338.3 140 O94772-1 140 100% 0 0

Chromosomal Locations for CCDS 6396.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 8 (NC_000008.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8See the combined annotation on chromosome 8 in Sequence Viewer

Chromosome Start Stop Links
8 143158250 143158485 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 143158803 143158922 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 143159582 143159648 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (423 nt):
ATGCTGCCTGCAGCCATGAAGGGCCTCGGCCTGGCGCTGCTGGCCGTCCTGCTGTGCTCGGCGCCCGCTC
ATGGCCTGTGGTGCCAGGACTGCACCCTGACCACCAACTCCAGCCATTGCACCCCAAAGCAGTGCCAGCC
GTCCGACACGGTGTGTGCCAGTGTCCGAATCACCGATCCCAGCAGCAGCAGGAAGGATCACTCGGTGAAC
AAGATGTGTGCCTCCTCCTGTGACTTCGTTAAGCGACACTTTTTCTCAGACTATCTGATGGGGTTTATTA
ACTCTGGGATCTTAAAGGTCGACGTGGACTGCTGCGAGAAGGATTTGTGCAATGGGGCGGCAGGGGCAGG
GCACAGCCCCTGGGCCCTGGCCGGGGGGCTCCTGCTCAGCCTGGGGCCTGCCCTCCTCTGGGCTGGGCCC
TGA

Translation (140 aa):
MLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSHCTPKQCQPSDTVCASVRITDPSSSRKDHSVN
KMCASSCDFVKRHFFSDYLMGFINSGILKVDVDCCEKDLCNGAAGAGHSPWALAGGLLLSLGPALLWAGP


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