Conserved Protein Domain Family
Scythe_N
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cd01809: Scythe_N (this model, PSSM-Id:176404 is obsolete and has been replaced by 340507)
Ubiquitin-like domain of Scythe protein
Scythe protein (also known as Bat3) is an apoptotic regulator that is highly conserved in eukaryotes and contains a ubiquitin-like domain near its N-terminus. Scythe binds reaper, a potent apoptotic inducer, and Scythe/Reaper are thought to signal apoptosis, in part through regulating the folding and activity of apoptotic signaling molecules.
Links
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Statistics
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PSSM-Id: 176404
Aligned: 20 rows
Threshold Bit Score: 105.387
Created: 8-May-2010
Updated: 17-Jan-2013
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P46379      17 LEVLVKTldsQTRTFIVGAq--mNVKEFKEHIRASVSI--PSEKQRLIYQGRVLQDDKKLQEYNV-GGKVIHLVER 87   human
EAK98092     5 ITITIKSs--GDKKYEVTFdpsiTVSQLKELVAEKSDI--PAGSQRLIYSGKVLKDTETVTSYKVqNGHTIHLVKS 76   Candida albicans SC5314
EAA62611    12 ITFNIKAs--NDAKFTLTLpastPVSELKEKLSSSDYAdtPAERQRLIYSGRVLKDNDTLATYKIkDGHTIHLVKS 85   Aspergillus nidulans...
NP_982818    3 IKIQVKS---GQNRWEVSVeasgSVGELKQEIAKVSEI--PAENQRLIYSGKILKDDQTVESYKIaDGHAIHLVKS 73   Eremothecium gossypii
P48510       3 LNIHIKSg-qDKWEVNVAPe--sTVLQFKEAINKANGI--PVANQRLIYSGKILKDDQTVESYHIqDGHSVHLVKS 73   baker's yeast
NP_648132    3 INLKVKTldaRIHEFSIDNe--lTIRQFKDQIAEKTNI--AAENQRIIYQGRVLVDDKQVKEYDV-DGKVLHVAER 73   fruit fly
XP_380922   13 ITFKVKTsseGHQTITMSEt--aTVLDLKTKLAGEDFEniPVERQRLIYSGRVMKNDDTLSTYKIkNNNTIHMVKS 86   Gibberella zeae PH-1
EAA15858     3 INVSFKVt--GGKEFTISIeptiTVMELKQKCAEHVDI--PVESQRIIFKGKILKDKEPLTLYGVaDGNVMHLVRS 74   Plasmodium yoelii yo...
XP_330215   13 ITFKVKCsgdKNHTVTIAEs--aTVLQLKTLLAGEEYEniSPEQQRLIYSGKVMKDDEVLSFYKIkHMNTVHMVKR 86   Neurospora crassa
EAK87935    54 ISIVFKVs--GGTQFNISVprntIVKDLKDKISEPSNI--PSSQQRLIYKGRILKDSDSLDGMKVeSGHTMHLVKS 125  Cryptosporidium parvum
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