C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins
eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Jiyao W et al.(2023). "The conserved domain database in 2023.",