2EE6,2DIA,2DMB,2DI7


Conserved Protein Domain Family
IG_FLMN

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smart00557: IG_FLMN 
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Filamin-type immunoglobulin domains
These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
Statistics
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PSSM-Id: 214720
Aligned: 117 rows
Threshold Bit Score: 64.9323
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2EE6_A      11 AHKVRAG-GPGLERG-EAGVPA--EFSIWTREAG--AGG---------------------------LSIAVEGPS--KAE 55   human
AAF46895  1465 ADKVQLM-GRGLAAA-QAGEAA--HFTIDASNAP--AGR---------------------------PEVILTSQDntSLP 1511 fruit fly
AAF46895  1091 GKEISVS-GLGLYQS-RVGKTT--SFAIDTVKRpa--rE---------------------------FDVVVSGPGgqALP 1137 fruit fly
AAF46895   188 RVLLNLSn---LELI-PVNRPS--SFHITVSGGG--AAE---------------------------LAVSVRGPQg---E 229  fruit fly
O96103      41 AFEVIVD-HDDGDKP-KVGSPCdvNLAIDDVHLpedLDK---------------------------LSAELTRPSgkKEP 91   Hydra magnipapil...
Q9YGW5     249 SLR---------QSHlKVGASAdiPLDIAESDL----SQ---------------------------LAASVTAPSgrKEP 288  chicken
XP_858268 1827 srhVSAY-GPGLSHG-MVNKPA--TFTIVTKDAG--EGDdsmrtsqlnvgtstdvslkitesdlslLTASIRAPSgnEEP 1900 dog
ACY39993  3336 iSRIMVR-GDGLHRA-VLKEHN--EFIIDGSDINk-EGR---------------------------ITATLLG-SkaDIP 3382 nematode
ACY39993  2111 PAKTTVSkIPSL--S-RVGQPS--SLVVEVS--G--HDQ---------------------------LEIRVLDSKksEIG 2154 nematode
ACY39993  2286 ataqatatgagLERI-PVDEET--EIQILT-DEI--DSA---------------------------PEARVRDPQgnDLP 2332 nematode
2EE6_A      56 ITF-DDHKN---GS-CGVSYIAQEPG--NYEVSIKFNDEHIPESPYLVPVIAP 101  human
AAF46895  1512 VSL-AQPRPs-eNI-WLASYTPLKSTtgTLNLSVKWNGRLVKGCPLTVAVGSS 1561 fruit fly
AAF46895  1138 VRC-YQTKN---GH-LQAEFTINKPG--QCVIEVLHQSKPLPGSPFTCESFDS 1183 fruit fly
AAF46895   230 LPV-RVTGDihaG--FTAEFTPTTVG--GHSINVEYNGFAVQGTPFLAKSYDA 277  fruit fly
O96103      92 IKC-KMAPD---GS-LALDFTPTEVG--KHLIEVKKNGRPVKGSPFEIFVDHP 137  Hydra magnipapillata
Q9YGW5     289 CQL-KRLRD---GH-VGISFVPQEVG--EHLVHISRGGQPLPRSPITVSISQA 334  chicken
XP_858268 1901 CLL-KRLPN---RH-IGISFTPKEVG--EHVVSVRKSGKHVTNSPFKILVGPS 1946 dog
ACY39993  3383 VRI-QQLGH---NV-YKATYTPLTGG--TYELHILWNGKHVKGSPFAVSADts 3428 nematode
ACY39993  2155 TDI-VEIEP---GH-MQINFTPAQVG--DHEIDVRYGGVPVTGSPFTCRAYDP 2200 nematode
ACY39993  2333 VNVtRSREN---ETlHIATYVPKCVG--NHLIDIFLQGEPIAGSPFTAKAYDA 2380 nematode
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