1OP4,1Q55


Conserved Protein Domain Family
Cadherin_pro
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smart01055: Cadherin_pro 
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Cadherin prodomain like
Cadherins are a family of proteins that mediate calcium dependent cell-cell adhesion. They are activated through cleavage of a prosequence in the late Golgi. This domain corresponds to the folded region of the prosequence, and is termed the prodomain. The prodomain shows structural resemblance to the cadherin domain, but lacks all the features known to be important for cadherin-cadherin interactions.
Links
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Statistics
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PSSM-Id: 214999
Aligned: 35 rows
Threshold Bit Score: 76.5479
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1OP4_A         33 KTgfpeDVYSAVLPKDVHEGQPLLNVKFSNCNRKRKVqYESSEPaDFKVDEDGTVYAVRSFPLTAEQAKFLIY-AQDKET 111  house mouse
NP_001159998   33 K------TVTLHVPAKLDAEKFIGRVNLKECFKSA-TlIHSSDP-DFQILEDGSVYTTHAILLSSEKSSFTIL-LSNTET 103  cattle
XP_001515354  156 K------KVVLKVPSHLQAGTLVGKVDLDECLTSANI-ILSNDP-DFRVLEDGSVYATNAIRLSSEQKAFTIL-LSDTQK 226  platypus
XP_001380481   32 K------KVVLKVPSHLQADTLVGRVNLEECFKSADL-IISSDP-DFRILEDGSVYTTKDIKFSSEKRIFSIL-LSDSQK 102  gray short-ta...
XP_001380494   13 KR------VTLNVPSTLEAETFVGRVNLDECLPSANI-IRSSDP-HFRILEDGSVYTTSTVVLSSEKKVFTIL-LFNREK 83   gray short-ta...
XP_426081     103 K------KVTFHVPSVLEADTLVGRVNINECLQSAEh-ISSSDG-SFKVLEDGSVYTTSAVSLSDEKRTFTIL-LKDLQE 173  chicken
NP_038533      33 K------EVVLQVPSELPAEKFVGRVNLMDCLKSADIv-HLSDP-DFQVLEDGSVYTTSSVVLSSGQRSFTIW-LFSTDS 103  house mouse
AAI55705       25 vftdtcEKVKLYVPSVIYSGHLIGKVNLRHCLDSDALsIQSSNP-DFLILEDGSIFAQKRISLAGKTW-FTIR-LLDSAT 101  western clawe...
XP_001496386   31 Q------KISLQVPSHLQAETLVGKVNLKECLQSASL-VLSSDP-DFRILEDGSIYTTHDLILSSERKS-FSIfVLDSQR 101  horse
XP_547623      22 lscdacqkislqvPSHLQAETLVGKVNLKECFQSASL-ILSSDP-DFRILEDGSIYTTHDLILSSERKS-FSIfPSDSQS 98   dog

1OP4_A        112 QEKWQVAV 119  house mouse
NP_001159998  104 QEEKEILV 111  cattle
XP_001515354  227 SEQKELEI 234  platypus
XP_001380481  103 LEEKNIEI 110  gray short-tailed opossum
XP_001380494   84 KEQKHIVV 91   gray short-tailed opossum
XP_426081     174 HVEKKILI 181  chicken
NP_038533     104 QEEREISV 111  house mouse
AAI55705      102 LTEKKIRV 109  western clawed frog
XP_001496386  102 KEQKEIEI 109  horse
XP_547623      99 QEQKKIEI 106  dog
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