1346737 27 KYLfsmtqIHQINDIDVHRITSGQVITDLTTAVKELVDNSIDANANQIEIIFKDYGLESIECSDNGDGIDPSNYEFLALK 106 baker's yeast 19173567 1 ------meIKRLPSDVISRISAGEVITRPYNILKETIENSLDANSTHITIKMEQDGLT-LTVEDDGDGIHESDFELLCKQ 73 Encephalitozoon cun... 19074926 1 -------mIRKLPEDVGKRIRAQRSVQSIYIVVKELIENAIDSGCTWIRILVDDAITV----EDNGCGISDLDKVGVEGA 69 Encephalitozoon cun... 1709684 1 MST-----VKPIDANTVHKICSGQVITDVASAVKELVENSLDSGATTIEIRFKNYGINSIEVVDNGSGIDAGDYESIGKK 75 fission yeast 19112991 1 MDVnsrakIRPLDQLVINKIAAGEIIERPENAIKELIENSLDAGSTSIDVLLKDGGLKLLQITDNGSGIQYDDLPYLCQR 80 fission yeast 15639295 29 MHEtsykpIHRLSPDTAKKIAAGEVIERPASVVRELLENALDAGATKIHLEINAGGCALIRVSDNGHGMSPQDLLLCAEA 108 Treponema pallidum 1709056 1 MSLr----IKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITDNGSGINKADLPILCER 76 baker's yeast 6325093 1 MSQh----IRKLDSDVSERLKSQACTVSLASAVREIVQNSVDAHATTIDVMIDLPNLS-FAVYDDGIGLTRSDLNILATQ 75 baker's yeast 20455095 1 MASt----IQALPQEVVYLITAGEVIDSFAAVVRELVENSLDAGANRIVVYLWPQQWR-VRVADNGCGMNLDDLQQAASA 75 Nostoc sp. PCC 7120 16329972 5 EKSm----IQVLDRQLVDLIAAGEVIDSPLAVVRELVENALDAGADRILVRVWWDQWR-LEVLDNGQGMDVTELKTSVLP 79 Synechocystis sp. P...
1346737 107 HYTSKIAKFQD----VAKVQTLGFRGEALSSLCGIAKLSVITTtSPPKADKLEYDMVGHITS---KTTTSRNK------- 172 baker's yeast 19173567 74 YCTSKLTKEEE----LFSLSSYGFRGEALSSISRCARIKVRSK-RREGEIGYEAVYRDTEMIt--IKGVGMKD------- 139 Encephalitozoon cun... 19074926 70 TSKESMAYYVLgyadRVEKFSYGFRGQALSCLAEVCDLEIISR--SEHSFALRKDFSTNAIS-----KCARER------- 135 Encephalitozoon cun... 1709684 76 HFTSKITDFED----LEALQTFGFRGEALSSLCAVGQVIISTAtQNEAPKGVQLNLDHEGSLk-dKLTIPFQR------- 143 fission yeast 19112991 81 FSTSKIDNFND----LQHLQTFGFRGEALASISHVAKVTVVTKlSSDIHAWKAFYVDGALAPispGMSPAPQPcag---- 152 fission yeast 15639295 109 HTTSKISSADD----LLQLRTLGFRGEALASIAAVSRLHLTSTrSGPLAWHYQPKAAGTAAHv-pPVPQGTEAgvlep-a 182 Treponema pallidum 1709056 77 FTTSKLQKFED----LSQIQTYGFRGEALASISHVARVTVTTKvKEDRCAWRVSYAEGKMLE---SPKPVAGKd------ 143 baker's yeast 6325093 76 NYTSKIRKMND----LVTMKTYGYRGDALYSISNVSNLFVCSKkKDYNSAWMRKFPSKSVMLsenTILPIDPFwkicpws 151 baker's yeast 20455095 76 HSTSKIRSSAD----LWKIHSLGFRGEALHSLTTLADVEIISR--APENVGWRVVYGDSGKAv--HVEATAIAp------ 141 Nostoc sp. PCC 7120 16329972 80 HATSKISTQAD----LQRIKTLGFRGEALHSLAQVARLTISSRsVASPGCGWRITYSPQGSPe--QIEPVAIAm------ 147 Synechocystis sp. P...
1346737 173 ----GTTVLVSQLFHNLPVRQKe-FSKTFKRQFTKCLTVIQGYAIINAAIKFSVWNItpkGKKNLILSTMRNSSMRKNis 247 baker's yeast 19173567 140 ----GTIVEIKNIFYNNKVREK--HFSKKREEIREMMWLVGMYSVFNSRISFELFYGeklQELPKSRVCVGEDGYSNEd- 212 Encephalitozoon cun... 19074926 136 ----GTTVHVRNLFKNCPLRRPm-ADSGLKRDLGKICSLIESYRCAN-KINFTLFHK---------RKVLLSCGGYET-- 198 Encephalitozoon cun... 1709684 144 ----GTSVMVNDLFCTLPVRRKl-LEKNYKREFSKAISLLQAYATISTNKRFMVYHQ---TKNSGKLLQLSTNSNKDMk- 214 fission yeast 19112991 153 --kqGTVITAEDLFYNVRSRKS--ALKNGSEEFRRIMILVQKYAIHNDQVSFNCKKV---GDTVASLSLSSRLSKADK-- 223 fission yeast 15639295 183 slerGTVVRVEQLFENFPARKR--FLGRQSAETTLCRSALIDVSLAHHPVEFRFTVD---GTHKLTLLSQQTRKDRCL-- 255 Treponema pallidum 1709056 144 ----GTTILVEDLFFNIPSRLR--ALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKF---GDSNYSLSVKPSYTVQDR-- 212 baker's yeast 6325093 152 rtksGTVVIVEDMLYNLPVRRRilKEEPPFKTFNTIKADMLQILVMHPMISLNVQYT---DKLRINTEVLFRSKNITEg- 227 baker's yeast 20455095 142 ----GTVVTVSNLFASCAARRQ--GLPTTAQQMKAVQATIQQIALCHPQTTWQVWQN---DRIWFTISPAATAGQLIPqf 212 Nostoc sp. PCC 7120 16329972 148 ----GTRVEVRQLFANFPQRRQ--AFAKSQQFWRPMVTYLQQLALCHPQVTWQLWQD---ERLRLSLSPGPNPEAILLqc 218 Synechocystis sp. P...
1346737 248 svfGAGGMRGLEEVDLVLDlnpfknrmlgkytDDPDflDLDYKirVKGYISQNsFg-CGRNSKDRQFIYVNKRPVEYS-- 324 baker's yeast 19173567 213 ---RVKRKVGMLNELYKAD--------------GKLlfVSDKE--YLVIFSTQ----QFCLRKGMLVLFVNGRLVVSQ-- 267 Encephalitozoon cun... 19074926 199 ----VREYFESNYPSFAGK-------------------CMEVCngQMDLFMLP-----VCVKEPKQLMFSERRPISNR-- 248 Encephalitozoon cun... 1709684 215 --lNIMNVFGTKVSSSLIP---------------WN---DGI---IEGYISRPhVg-STRASNERQMLFINRRLVNLP-- 268 fission yeast 19112991 224 ----IRHIYGPRVASHLRDfs----------lGEGQssIVGFS--ANGFISNA----DFQDKKSNLILFINNRLVESV-- 281 fission yeast 15639295 256 ---ETQMLKGDPALFHTIE--------------GGD---CSFH--FHLVLSEP-A--ICRRERRGIFTFVNGRRIFDY-- 308 Treponema pallidum 1709056 213 ----IRTVFNKSVASNLIT-------------FHISk-VEDLN--LESVDGKVcNlnFISKKSISPIFFINNRLVTCD-- 270 baker's yeast 6325093 228 ---LTKHQQMSQVLRNVFGa------------IIPPdmLKKVSlkFNEYQIEGiIskMPVGLKDLQFIYINGRRYADSaf 292 baker's yeast 20455095 213 lpqLRPSDLQEIKLEIPNPenp-------qlsTNNK--PNASA--LALVVGLPdR--CHRHRPDWVRVAINGRMIKLP-- 277 Nostoc sp. PCC 7120 16329972 219 lksLQAGQLGYTQQSLSLPv-----------dLENQ--ATSAQ--LSLTFGYPdR--CHRPRPDWLIIAINGRPVNVP-- 279 Synechocystis sp. P...
1346737 325 --------------TLLKCCNEVYKTFN-NVQFPAVFLNLELPMSLIDVNVTPDKRVILLHNERAVIDIFKTTLSDYYNR 389 baker's yeast 19173567 268 --------------EMKESLFKVYKDILpPQKQPLIYLELYVEKSMVDVNVHPSKREVLFSNEESMTQRLCKCIAERLSK 333 Encephalitozoon cun... 19074926 249 --------------RILNAVKSEFGLYVeGS--PTFVLVIKGYG---DVNVSADKSEVIFADEAGILNLLRSEIGRFFSS 309 Encephalitozoon cun... 1709684 269 --------------KIARVIQEVFKP-YsMAQSPFFAINLRITNGTIDINVSPDKKSVFLSEEDSIIEFIKNSLQNLCES 333 fission yeast 19112991 282 --------------ELRHALEETYAKYLhKGASYFVYLSLNMSPEQLDVNVHPSKRIVHFLYDQEIATSICDKLGEILER 347 fission yeast 15639295 309 --------------GLVQALVLGSEGYFpNGTFPVACLFLTVNSERIDFNIHPAKKEVHLQDYAHIRHTLSRSVAHFYRQ 374 Treponema pallidum 1709056 271 --------------LLRRALNSVYSNYLpKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAELSA 336 baker's yeast 6325093 293 qgyvdslfqaqdfgEKGMSLLKTKSVGKpYRSHPVFILDVRCPQTIDDLLQDPAKKIVKPSHIRTIEPLIVKTIRSFLTF 372 baker's yeast 20455095 278 --------------ELEQTILAAFHRTLpRDRYPLCFVHLLISPDQINWNRNPAKTEIYLHDLSYWQEQVTQAINQALRI 343 Nostoc sp. PCC 7120 16329972 280 --------------ELTQTILAVFHRTLpRQRYPLCFAHWQLPPQCIDWHRHPAKTEIYLQDLPHWQGQLKTLLHQSLAI 345 Synechocystis sp. P...
1346737 390 QELALPkrmCSQsEQQAQKRLKTEVFDDRSTTHESDNENYHTARSESNQSNHAhfnsttgvidksngteltsvmdgnytn 469 baker's yeast 19173567 334 LDYEQK----------PLKPLPKDSFQSP----------IKVYSDPTSQS------------------------------ 363 Encephalitozoon cun... 19074926 310 EMYLNP---ASAvRRQKSNVQERSDAGEDSREDLMARGSSRISEDFPFLKPAKt-------------------------- 360 Encephalitozoon cun... 1709684 334 CGHAIS---CSRsQSIFSYSSQIPDSSGDSTDQELPQSIPATESETSDDSSFSykrspckrklv---------------- 394 fission yeast 19112991 348 TDTERSyplQAMiPSISNTKNAESSSQKAVRTYENYLVRTDPRERSIKSMLSDn-------------------------- 401 fission yeast 15639295 375 CTIAHY---------VRAEPAHAPATQGN-------------APTHSSPPCTG--------------------------- 405 Treponema pallidum 1709056 337 IDTSRTfkaSSIsTNKPESLIPFNDTIESDRNRKSLRQAQVVENSYTTANSQLrkakrqen------------------- 397 baker's yeast 6325093 373 QGYLTP-------DKSDSSFEIVNCSQKTATLPDSRIQISKRNQVLNSKMKIAri------------------------- 420 baker's yeast 20455095 344 SAANIP---ESV--QTTRVSQLLKAAEEK--------------GNYNFNPRN---------------------------- 376 Nostoc sp. PCC 7120 16329972 346 LGNDAP---P-------RLNQLLKAAEPK--------------GVYQLQGASS--------------------------- 374 Synechocystis sp. P...
1346737 470 vtdvigsecevsvdssVVLDEGNSSTPTKKLPSIKTDSQNLSDLNLNNfsnpefqnitspdkarslekvveepvyfdidg 549 baker's yeast 19173567 364 -----------------IAECLEKETTE-------RREFRLFSLSKLR-------------------------------- 387 Encephalitozoon cun... 19074926 361 ----------------TIPHREKAQQRSAGPPEGMESSKELLPEETVGi------------------------------- 393 Encephalitozoon cun... 1709684 395 ------eataqpaistSVAEGASLAQVSKPLPERLQKDSMRRSSPLNEkvtassermkkklalfasstdtsmqktidssf 468 fission yeast 19112991 402 -----------------FLQRSSNNYDNEIIEKVDSANSNKNATNDIK-------------------------------- 432 fission yeast 15639295 406 ----------------VREEPAAPCAHTPRYESLFPLPVQHAHLLPP--------------------------------- 436 Treponema pallidum 1709056 398 ---------klvridaSQAKITSFLSSSQQFNFEGSSTKRQLSEPKVTnvshsqea------------------------ 444 baker's yeast 6325093 421 --------------nsYIGKPAVNGCRINNSTINYEKIKNIRIDGQKS-------------------------------- 454 baker's yeast 20455095 377 ------------------ANPADNTQN----------------------------------------------------- 385 Nostoc sp. PCC 7120 16329972 375 -----------------LTETVLGYPK----------------------------------------------------- 384 Synechocystis sp. P...
1346737 550 ekfqekavlsqadglvfvdnechehtndcchqerrgstdteqddeadsiyaeiepveinvrtplknsrksiskdnyrSLS 629 baker's yeast 19173567 -------------------------------------------------------------------------------- Encephalitozoon cun... 19074926 394 ----------------------------------------------------------------------------eNTK 397 Encephalitozoon cun... 1709684 469 plkqpinkpssnpnnlllndpspastpvaktinlneiesvhnaesvstlssiprteqtsvanripsktaalqklkffQSR 548 fission yeast 19112991 433 -----------------------------------------------------------------------------DLQ 435 fission yeast 15639295 437 -----------------------------------------------------------------------------SPP 439 Treponema pallidum 1709056 445 ----------------------------------------------------------------------ekltlneSEQ 454 baker's yeast 6325093 455 -----------------------------------------------------------------------------RLR 457 baker's yeast 20455095 -------------------------------------------------------------------------------- Nostoc sp. PCC 7120 16329972 -------------------------------------------------------------------------------- Synechocystis sp. P...
1346737 630 DGLthRKFEDEILEYNLSTKNfkeiskngkqmssiiskrkseaQENIIKNKDELedfeqgekyltltvskNDFKKMEVVG 709 baker's yeast 19173567 388 -----LEIVDVDTTFFR---------------------------------------------------------SLSYVG 405 Encephalitozoon cun... 19074926 398 VETvsSSPLKEHESPPETEKKnee-----------------vgSKENFAAGAYSffrndelvqskisfskGDFGRLEIIG 460 Encephalitozoon cun... 1709684 549 PLDglNKFSKKINISLSGVQKdivrsdall-----kfsnkigvVHDISDENQEDhlnl--------tvhkADFLRMRVVG 615 fission yeast 19112991 436 TEEivEEGNSIDLESIKSLQKq--------------------vINSMHVLATN------------------ILTEHKYVG 477 fission yeast 15639295 440 HISceHARDCTHPAPAAEG------------------------DAPVHNHTHTG--------------------AFKVLG 475 Treponema pallidum 1709056 455 PRDanTINDNDLKDQPKKKQKlgdykvpsiaddeknalpiskdGYIRVPKERVNvnltsikklrekvddsIHRELTDIFA 534 baker's yeast 6325093 458 NKLssRPYDSGFTEDYDSIG------------------------KTITDFSISR----------------SVLAKYEVIN 497 baker's yeast 20455095 386 --------------------------------------------------------------------------YLKAVA 391 Nostoc sp. PCC 7120 16329972 385 --------------------------------------------------------------------------AFKAIA 390 Synechocystis sp. P...
1346737 710 QFNLGFIIVTrk----vdNKYDLFIVDQHASDEKYNFETLQAVTVFK----SQK--LIIPQPVELS----VIDELVVLDN 775 baker's yeast 19173567 406 VKDRDTILVQ--------HGSSLLNCKTVPLLKEYLYQSLINDFGN-----------FEKKRTLVR------LRCKMDDK 460 Encephalitozoon cun... 19074926 461 QFNNGFIITKle----knKKTYLVAVDQHAADEIRNFEDIKKTFCLK----KQS--VISPVKLDLT----PIEEMVVSDN 526 Encephalitozoon cun... 1709684 616 QFNRGFIVVV--------HGNNLFIIDQHASDEKFNYEHLKSNLVIN----SQD--LVLPKRLDLA----ATEETVLIDH 677 fission yeast 19112991 478 LVCPTRRIAAv------qHNIGLYVVDYGKLSYHLFYQICLTEFGNYgefvLETp-LSISDLFEIVn--gDEDKSESEKF 548 fission yeast 15639295 476 QVAGTFIAVE--------RNNALYLIDQHAAHERIIFDTLQRNLGT-----AQI--LLIPYHIHPRs---DEEARIMHRA 537 Treponema pallidum 1709056 535 NLNYVGVVDEerrlaaiqHDLKLFLIDYGSVCYELFYQIGLTDFANFgkinLQS--TNVSDDIVLYnllsEFDELNDDAS 612 baker's yeast 6325093 498 QVDKKFILIRcldq-sihNCPLLVLVDQHACDERIRLEELFYSLLTEvvtgTFVarDLKDCCIEVD----RTEADLFKHY 572 baker's yeast 20455095 392 QVSNTYIVAE--------HPGGMWLVEQHIAHERVLYEQLCDNWRLi---pVEP--PIILYQLSPA-----QVAQLQR-- 451 Nostoc sp. PCC 7120 16329972 391 QVCQTYVVVE--------HDQGIWLVEQHVAHERVLFEQLQRHWQCl---pLEQ--PLVLQGFNPE-----QVERLQN-- 450 Synechocystis sp. P...
1346737 776 LPVFEKNGFKLKIDEEEEfgsrVKLLSLPTSKQTLFDLGDFNELIHLIKEdGGLRRDNIrc------------------- 836 baker's yeast 19173567 461 TRALLNDYFSIEVIEEHI----VGIPIISTICIDAPELWSGFEIRRSSE------------------------------- 505 Encephalitozoon cun... 19074926 527 VELFERNGFVVK--D-------GMLETVPVYKNQTFGIREFRELLEDVKN----EEYEFr-------------------- 573 Encephalitozoon cun... 1709684 678 IDLIRRKGFGVAIDLNQRvgnrCTLLSVPTSKNVIFDTSDLLEIISVLSEhPQIDPFSS--------------------- 736 fission yeast 19112991 549 TRLLVSRRDMLKDYFSISvtsgGLLTAVPMLSPKYHPPFEQLPLLISSLTpKFFDWLDEks------------------- 609 fission yeast 15639295 538 CTELSPAGFRFHEEPDGS----WHVTAVPLHWRGSEE-QLAHDILYSGK------NAHD--------------------- 585 Treponema pallidum 1709056 613 KEKIISKIWDMSSMLNEYysieLVNDGLDNDLKSVKLKSLPLLLKGYIPSlVKLPFFIYrl------------------- 673 baker's yeast 6325093 573 QSEFKKWGIGYETIEGTMetslLEIKTLPEMLTSKYNGDKDYLKMVLLQHaHDLKDFKKlpmdlshfenytsvdklywwk 652 baker's yeast 20455095 452 ------IGLDIDIFGEQL----WAVRNLPAMLQQREDCAEAILELSWG----------G--------------------- 490 Nostoc sp. PCC 7120 16329972 451 ------LGLEIDPFGEDI----WAVRSLPALLQGQEEIIAILRELSQV----------F--------------------- 489 Synechocystis sp. P...
1346737 837 ------sKIRSMFAMRACRSSIM--------IGKPLNKKTMTRVVHNLSELDK------PWNCPHGRPTMRHLMELRDWS 896 baker's yeast 19173567 506 --------YETLKNIIDVVSTLY--------SGVEMSTKLFNILKRRIIGTAR---------ALECF--GLVVTLKELYR 558 Encephalitozoon cun... 19074926 574 -------KARSIIASKACRTSVM--------IGDVLSMADMKRIVKSLASLER------PWKCPHGRPTFMVLNEAEA-- 630 Encephalitozoon cun... 1709684 737 -------RLERMLASKACRSSVM--------IGRALTISEMNTIVRHLAELSK------PWNCPHGRPTMRHLLRLKDI- 794 fission yeast 19112991 610 ------cLNGIMKAIAKFYVPLPls----yeESDVKSIRSLESCLEDYLFPEFrrrvicPKKVFEEKCIYQITSLPRLYN 679 fission yeast 15639295 586 -------ILRHVLATCACRSACK--------DGTILDDATLHSLVEQAFALP-------QSRCPHGRPIWIVIGRDELFK 643 Treponema pallidum 1709056 674 ------gKEVDWEDEQECLDGILreiallyiPDMVPKVDTSDASLSEDEKAQF------INRKEHISSLLEHVLFPCIKR 741 baker's yeast 6325093 653 ysscvptVFHEILNSKACRSAVM--------FGDELTRQECIILISKLSRCHN------PFECAHGRPSMVPIAELK--- 715 baker's yeast 20455095 491 -------DLQTAQVAVACRSAIR--------NGTPMSLPEMQKLLDDWQRTRN------PRTCPHGRPIYLSLDESSLSR 549 Nostoc sp. PCC 7120 16329972 490 -------SLSTAQAAIACRSAIK--------NGMELDRIAINKLIEQWQQCDN------PHTCPHGRPIYLALDESSLAR 548 Synechocystis sp. P...
1346737 897 SFSKD 901 baker's yeast 19173567 559 NFERC 563 Encephalitozoon cuniculi 19074926 ----- Encephalitozoon cuniculi 1709684 ----- fission yeast 19112991 680 VFERC 684 fission yeast 15639295 644 RIKRT 648 Treponema pallidum 1709056 742 RFLAP 746 baker's yeast 6325093 ----- baker's yeast 20455095 550 FFRRH 554 Nostoc sp. PCC 7120 16329972 549 FFRRN 553 Synechocystis sp. PCC 6803
Jiyao W et al.(2023). "The conserved domain database in 2023.",