1HDH_A 1 MSKRPNFLVIVADDLGFSDIGAFGGEI---ATPNLDALAIAGLRLTDFHTASTXS-PTRSMLLTGTDHHIAGIGTMAEAl 76 Pseudomonas aeruginosa 17988454 1 ----MNVLYIDIDSLRRDHLGCYGYHRn--TSPTIDAIAREGVRFENIYVSDVPChPSRTALWSGRHGFRTGVVGHGG-- 72 Brucella melitensis 1175731 -------------------------------------------------------------------------------- Haemophilus influenzae 15597529 4 PKPIRNVLYIMCDQLRRDYLSCYGHPYl--hTPNIDRLAAEGVRFARAYTQGTICgPSRMSSYTGRYVSSHQVAWNAVP- 80 Pseudomonas aerugin... 14521390 3 gkhRGSAMVFKSITTIAKSIVKRNDATk--rLVLRVYNQYQGRKAKKELYLRIKNiDFDEYIDTSNKPDLNVIILTVDCl 80 Pyrococcus abyssi 15602463 1 ------------------MLGAYGHQVvktpnIDR--LAQDGIRFNNAFTPASVCgPARTSLFTGLMPSSHGIIKNGEKg 60 Pasteurella multocida 15789395 1 ----MNVLYVTVDALRADHVTPELMPN-------VSGFVDRSIEYERCYANGPGTpWSFPALLGSQYSGANDGVGIP--- 66 Halobacterium sp. N... 15790157 1 -------MAESGSDIALVVLDALRKDA-----FDAHFSWMDGVRYENAWSTTHYSpAAHGSLFTGKYGSEIGVHAKSP-- 66 Halobacterium sp. N... 15790369 1 -----MVVTSAAGTVLVTVDSLRADARsrvETPTLDALADSGTVFERAYAHGNWT-PFSFPSVLGDSHVFAADGAIG--- 71 Halobacterium sp. N... 15804278 1 -mkRPNFLFIMTDTQAPNMVGCYSGKPlntqnIDS--LAAEGIRFNSAYTCSPVCtPARAGLFTGIYANQSGPWTNNVAp 77 Escherichia coli O1...
1HDH_A 77 tpelegkPGYEGHLNERVVALPELLREAGYQTLMAGKWHLGLKPEq---------TPHARgfer---------sfslLPG 138 Pseudomonas aeruginosa 17988454 73 -------TACEPFREGASRAWAGTFYEEGWMKALRDLDYYTT----------------T------------------ISS 111 Brucella melitensis 1175731 -------------------------------------------------------------------------------- Haemophilus influenzae 15597529 81 -------------LPLEELTLGDYLRAAGVRTALVGKTHATANLEgmrr---lgiDPASArgaala-----eagfepYDR 139 Pseudomonas aerugin... 14521390 81 r-----yLNLSFTGYQRETTPFMDSLKAKFRAVSAAPWTYPSVAS----------ILTGLy----------------pHN 129 Pyrococcus abyssi 15602463 61 g-----------tgE-ISQQAPNIAKLAGYNTYVVGKWHVGTKSVpedydikghnFDGYGypgsgvyknlvfnqpptHSN 128 Pasteurella multocida 15789395 67 --------G----EDDSRPTLAEVLRDEGYETAGFTDNHFASS-------------DYN-------------------YD 102 Halobacterium sp. N... 15790157 67 ------------TLDCDQPTLAELLRDSGYETHGFSANTYISK----------------------------------YFD 100 Halobacterium sp. N... 15790369 72 ---------------VGDTTLAGRLADAGVRTAGVNAANGFLT--------------EH-------------------WG 103 Halobacterium sp. N... 15804278 78 g--------------kNISTMGRYFKDAGYHTCYIGKWHLDgh-----------dYFGTGecp------------peWDA 120 Escherichia coli O1...
1HDH_A 139 AANHYGFEPPYDESTPRILKGTPALYVEDE-RYLDTLP--EG-FYSSDAFGDKLLQYLKERDQSRPFFAYLPFSAPHWPL 214 Pseudomonas aeruginosa 17988454 112 FGERHGCWHWYTGFNEVMNCGKGGMENADEiVPMAID---WIaRNKSRKWFLHVNLWDPHTPYRVPEEWGDPFAGEPLPA 188 Brucella melitensis 1175731 -------------------------------------------------------------------------------- Haemophilus influenzae 15597529 140 NDGVYPDDPAFADKRERAPYTHYLRRLGFTgDNPWHDWanAAaGADGEILSGWRMRHAGLPTRLPEAHSETAYTTRRAMD 219 Pseudomonas aerugin... 14521390 130 HNAYIHSKIKNFDTLKAFKPIKKSVLTLPEiLFAFGYEiyFGtAIDVASYPLKSRVVPKLYLGDTPAEELLNDLRKWISK 209 Pyrococcus abyssi 15602463 129 RYKEWLEEKGFEFPEVSKAYFGDNPHLRVQeLCGFLSG--TKeQTIPYFIIDEAKRYIQESLEENKPFFTWINFWGP-HT 205 Pasteurella multocida 15789395 103 RGMTTMFDAGATSSEKRLKQAVRKRLDHDGtLYQMLLR--GHhLIDDLLVKIQGRDTRFTRAETLIDSLVDWIDERNDQW 180 Halobacterium sp. N... 15790157 101 FDRGFDEFHSRTRVVGGNETAFNWPQFIKEnKDAGWRKypRLmREIARSDAKLLSSIKNGAEIKLKDIGLIDDDNTYEDG 180 Halobacterium sp. N... 15790369 104 YDRGFDTYDAFTDTNSRLGRTLAAHPTVQGwLQVGASP--FRrRSDGRERVDATR------MLDIEDRAVEFLSAASEPF 175 Halobacterium sp. N... 15804278 121 DY--WFDGANYLSELTEKEISLWRNGLNSVeDLQANHI--DEtFTWAHRISNRAVDFLQQPARAEEPFLMVVSYDEP-HH 195 Escherichia coli O1...
1HDH_A 215 QAPREIVEKYRGRYDagpealRQERLARLKELGLVEADVEAHPVLAlt-----------rEWEALEDEERAKSARAMEVY 283 Pseudomonas aeruginosa 17988454 189 WMTEEVLARSIAGYG-------PHSPQEPTGFSADNPHAHYTR-------------------MPAPIDSMEKVAAWFNGY 242 Brucella melitensis 1175731 1 -----MPEPYYSMYR------KEDVVLDKSFFTPLEGKPDHFRTi--------------sKMWGMWEASEDHWKEVITKF 55 Haemophilus influenzae 15597529 220 FIDEQGERPWCLHLSyikphwPYIAPAPYHALYRADQVLPALRAAPgeesdhpvyrafreHRESLNFSREDVRRQVIPTY 299 Pseudomonas aerugin... 14521390 210 RKNSFFAYLQLGDVHep--ivPPEKFRNYFGQVENIPNIERWDFRR--------------PEEQKGKEFEKYRRNRMLLY 273 Pyrococcus abyssi 15602463 206 P--CIVPEPYYSMYS------KDDVVLDESFFKPLEGKPGHFRTi--------------sKMWGMWEASEDHWKEVITKF 263 Pasteurella multocida 15789395 181 FAWLHPMDTHAPYEA-------PDDYQEQFLDEPIPRRRSQKLARK--------------ATHHPDELSDDEWELQQQLY 239 Halobacterium sp. N... 15790157 181 REALNYIQAASFASDhefvflNLMDAHGPYLAPPSYRTKEPERTLP--------------PATFSDAEDDVDSEALKTAY 246 Halobacterium sp. N... 15790369 176 FLWLHYMDTHTPYVP-------APRHLRATTDRRGAMLGMLSAHLR---------------VGLGLTVSSATAGELHTLY 233 Halobacterium sp. N... 15804278 196 P--FTCPVEYLEKYA------DFYYELGEKAQDDLANKPEHHRl----------------WAQAMPSPVGDDGLYHHPLY 251 Escherichia coli O1...
1HDH_A 284 AAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAegalleafpkfgpdllgfldrhydnslenigransyvwygprW 363 Pseudomonas aeruginosa 17988454 243 DAGVRYADEHIGHLIAALKEHGLYDNTIIVIGADHG-------------------------------------------- 278 Brucella melitensis 1175731 56 WGYITLIE------------------------------------------------------------------------ 63 Haemophilus influenzae 15597529 300 MGLIRQVDDQLGRLFQHMRASGRWDDTLIVFTSDHGD------------------------------------------F 337 Pseudomonas aerugin... 14521390 274 DNTLRYVDYAIERLYAFLEDSGLLDSTILLITADHGEefweha-------------------------------eleaeN 322 Pyrococcus abyssi 15602463 264 WGYITLIDDAIGELFAFLEQHNLYESTFLVATADHGD------------------------------------------A 301 Pasteurella multocida 15789395 240 KAECSYLDDQIGRLLDSFPEPER-ENTLLVFTADHG-------------------------------------------- 274 Halobacterium sp. N... 15790157 247 EDCVRYLSDIYAEIHEELLTEFD---YVIT-LADHG-------------------------------------------- 278 Halobacterium sp. N... 15790369 234 DATVRQVDTSIGRVLAALGDRRE--DTMVVVAGDHG-------------------------------------------E 268 Halobacterium sp. N... 15804278 252 FACNDFVDDQIGRVINALKPEQ-RENTWVIYTSDHGE------------------------------------------M 288 Escherichia coli O1...
1HDH_A 364 AQAATAPSRLYKA-FTTQGGIRVPALVR--YPRLSRQ-GAISHAFATVMDVTPTLLDLAGVRHPGkRWRGREIAE----- 434 Pseudomonas aeruginosa 17988454 279 -ENLGELNVWGDHqTADEFTCNVPLIIR--WPG---QaPGVNHGLHYHFDWPATLIDGLGGKVPS-VWDGKSFAPamr-- 349 Brucella melitensis 1175731 64 -----------------------------------------DDNLVYLHDLTSTVF----------DLANQKVPEsfegq 92 Haemophilus influenzae 15597529 338 LG---DHGLGEKE-FLLESAVGVPLLIRdpRPEADATrGRVEEALVQSIDVLPSILEAFAVEPAShRIEGRSLLPfvhga 413 Pseudomonas aerugin... 14521390 323 FYDPRGYYGVGHGhNVFNEIIEVPILFD----GAIKKkGDFTENRVSSVDIMPTVLDLLGVSHSL-TFDGQNVFEv---- 393 Pyrococcus abyssi 15602463 302 MGAHRMIEKGEF---MFDTTYNIPLIIK--DPKS-NRvNEQDDNLVYLHDLTSTVY----------DIAEQKIPTefqge 365 Pasteurella multocida 15789395 275 -EMHGEHGLGGHPqQFWEEVIHVPCAIS--APG---FeATTVNEQAALIDIPPTILDAVG-------IDAPEYWDg---- 337 Halobacterium sp. N... 15790157 279 --EAFGEYGTWSHsDLSPQVTNVPLAIS---SEDGLEeFSPTGKPVNLHDVFQTVLDLAGVEPET-STRGQSLRAa---- 348 Halobacterium sp. N... 15790369 269 EFLEHGHLAHYPK--LYDELVHVPLLVD--HPAGa---GGRVSTAVGLSDVPATVLDVMGGSTRG--FTGESLAPeirag 339 Halobacterium sp. N... 15804278 289 MGAHKLISKGAA---MYDDITRIPLIIR--SPQG-ERr--QVDTPVSHIDLLPTMM----------ALADIEKPEilpge 350 Escherichia coli O1...
1HDH_A 435 --PRGRSWLGWLSGEt-EAAHDENTVTGWELFGMRAIRQGDWKA---VYLPAP----------VGPATWQLYDLARd-PG 497 Pseudomonas aeruginosa 17988454 350 rnKNGGRDFLVLSQG----AWAVQRGVRFRHQNEDWLMLRTWHDg-lKDFGPVtl------fnLTSDPHEQTDLSQsrPD 418 Brucella melitensis 1175731 93 svLPIMRQHQDNQR---KGVLGQLAGHF-VYFEQRMWRRKDYK------LVFNatdvc-elynIRNDPEEMHN-----L- 155 Haemophilus influenzae 15597529 414 ppADWRRYAIAEYDYafQAPARERLGRPIDACRMYMVRSERWKYiayDGFRAQlf-------dLASDPGELRDLG----A 482 Pseudomonas aerugin... 14521390 394 -kNKKRPLLSEAAGYg-YEKKALIMGRYKLLYAPDDGVQWLFDLk--KDPSEQhpikdrevtsVFVDKLNKMLKED---E 466 Pyrococcus abyssi 15602463 366 tlLPITREKQQNDR---KGILAQLAGHF-VYFEQRMWRRKDYK------LVFNatdvc-elydVRRDPEEMHN-----L- 428 Pasteurella multocida 15789395 338 --MSVLPDEGTVQER---EYVFVDVESELNRNHAGVRRSDNWKL---MRHDDEgel----lldLDTNPEEDPEQTR---- 401 Halobacterium sp. N... 15790157 349 -kFDADRVAFLETHG----LSNERLNGILEEEHSQEIVDKYDKR---LSAIATas------gyVFEQFGETIESVG---D 411 Halobacterium sp. N... 15790369 340 tePTRGPITSVAVRGa-SVTQQPIPRHLGAGRPLVSARDGRWTYi--RDPERDthe----lydRASDPGEQTDVSG---T 409 Halobacterium sp. N... 15804278 351 niLAVKEPRGVMVE---FNRYEIEHDSFGGFIPVRCWVTDDFK------LVLNlftsd-elydRRNDPNEMHN-----L- 414 Escherichia coli O1...
1HDH_A 498 EIHDLADSQPGKLAeliehwkryVSETGVVEGASPFLVR 536 Pseudomonas aeruginosa 17988454 419 IVAHASRMLDEWYGtma---qcsDQDVDPLMTVLREGGP 454 Brucella melitensis 1175731 156 --FYDPQYNRIK-----------KEMLEEMRAEMKRlnd 181 Haemophilus influenzae 15597529 483 DPAHAAVREAHAG-----------MLFDWLRGLKRRTTI 510 Pseudomonas aeruginosa PA01 14521390 467 KRRLINALRKVRI-------------------------- 479 Pyrococcus abyssi 15602463 429 --FYDERYKDVK-----------KEMLEEMRVEMKRlgd 454 Pasteurella multocida 15789395 402 -LNDAPEAYRALTD---------SLDNHLDEMERRRSGE 430 Halobacterium sp. NRC-1 15790157 412 PVPDAERRMQELAAg-------iDRRTDAKAVEVSDevy 443 Halobacterium sp. NRC-1 15790369 410 ADPPLDALHAAT-----------RQRLDAIRTDGDAaaa 437 Halobacterium sp. NRC-1 15804278 415 --IDDAHFADVR-----------SKMHDALLDYMDKird 440 Escherichia coli O157:H7 EDL933
Jiyao W et al.(2023). "The conserved domain database in 2023.",