Conserved Protein Domain Family
PHD_UBR7
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cd15542: PHD_UBR7 
PHD finger found in putative E3 ubiquitin-protein ligase UBR7
UBR7, also termed N-recognin-7, is a UBR box-containing protein that belongs to the E3 ubiquitin ligase family that recognizes N-degrons or structurally related molecules for ubiquitin-dependent proteolysis or related processes through the UBR box motif. In addition to the UBR box, UBR7 also harbors a plant homeodomain (PHD) finger. The biochemical properties of UBR7 remain unclear.
Links
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Statistics
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PSSM-Id: 277017
Aligned: 35 rows
Threshold Bit Score: 60.0739
Created: 14-Aug-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Zn binding siteputative
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C C H [CH] C CClick to see conserved feature residue pattern help
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         # #                   #     #     #  #                                         
Q8N806       134 YCICKRPYpdped--eipdEMIQCV---VCE-DWFHGRHLgaipp----------------------------------- 172 human
XP_004991480  65 FCHCNRPYpddtlpedvneDMVQCV---LCE-DWFHTVGFdaahadvphpdsdsithpvsficgsgedhdvahrckhgaf 140 Salpingoeca sp....
NP_492187    138 FCTCDVFYpded----ggkELLQCE---ICE-DWFHEEHMpfkdvnyyyeei----------------------eansdt 187 nematode
XP_003093856 142 FCTCDAFYpde-----perAFMQCE---LCE-DWFHDDHTpatfvgteeg-------------------------qangd 187 Caenorhabditis ...
CDJ92457     168 FCVCKKAYpcee----tdeTMHQCV---ACE-DWFHLSHLdencatvae----------------------------ere 211 barber pole worm
CAP28113     166 FCTCDAYYpdda----hgfELYQCE---ICE-DWYHDSHTpsksiryet----------------------------ehe 209 Caenorhabditis ...
EFW40197     141 YCWCDRAEees-----thmMMVQCT---LCQ-DWYHKACIdertaehg------------------------------gm 181 Capsaspora owcz...
EME30610     113 FCYCEKEYsed------aeDMIQCF---VCE-DWYHVSCLnlkapwc-------------------------------ag 151 Galdieria sulph...
EMR11583     135 FCWCDADYdpat----derTMFQCL---LCE-DWFHDQCIgmeni----------------------------------- 171 Pneumocystis mu...
CDF90048     120 FCVCSKEYdpn-----sdaTMVQCVlgtECDeDWYHDYCIgkqmp----------------------------------- 159 Zygosaccharomyc...

Feature 1                  #  #
Q8N806       173 -esgdFQEMVCQAC 185 human
XP_004991480 141 yhgirQCICACQSC 154 Salpingoeca sp. ATCC50818
NP_492187    188 ilnrdIASAVCLVC 201 nematode
XP_003093856 188 asvqnTASMICSTC 201 Caenorhabditis remanei
CDJ92457     212 nagkqDFSLLCKDC 225 barber pole worm
CAP28113     210 peekePAAAICAGC 223 Caenorhabditis briggsae
EFW40197     182 pdlsqFAAFVCSGC 195 Capsaspora owczarzaki ATCC 30864
EME30610     152 nifeeEFDLVCSLC 165 Galdieria sulphuraria
EMR11583     172 knsddYDFFICRSC 185 Pneumocystis murina B123
CDF90048     160 -plesFDAFICSKC 172 Zygosaccharomyces bailii CLIB 213

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