4MZD,1AH2,3TI7


Conserved Protein Domain Family
Peptidase_S8
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pfam00082: Peptidase_S8 (this model, PSSM-Id:278510 is obsolete and has been replaced by 395035)
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Subtilase family
Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see pfam00089). Structure is an alpha/beta fold containing a 7-stranded parallel beta sheet, order 2314567.
Links
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Statistics
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PSSM-Id: 278510
Aligned: 46 rows
Threshold Bit Score: 129.069
Created: 15-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4MZD_A         91 SKKISVGIIDSGIM-----EE--------------HPDLSnslgnyfknl-------------vpkggfdneEPDETGNP 138  Lactococcus l...
P54683        378 GKGQILSIADTGLD-----GS--------------HCFFSdskypipfnqvnenhrkvvtyityhdnedyvnG------- 431  Dictyostelium...
WP_000253881  276 nitTSVSILDTGVN-----YN--------------NMLLSkvcc-------------------------ddfAVSWDPDW 311  Salmonella en...
WP_041230105  204 KNNVYICLLDTGVN-----NE--------------HILLK--------------------------------EFLSDKDS 232  Denitrovibrio...
WP_005951824   94 KKYPMVGVLDNGIAniemmSSwvyrdekqycperqHPT------------------------------------------ 131  Fusobacterium...
WP_004027347  282 TNEPTIGVIDTIIVdhtqvYFhewidyhyenskelEPILK---------------------------------------- 321  Ureaplasma ur...
CQD03916      201 KDAAVVCILDTGVQ-----DT--------------HPLLTdsigaadlhva----------------------------- 232  Mycobacterium...
WP_000273035  270 IPKTSVCILDSGIN-----HD--------------HPLISsfifsansrtydpswp-----------------------q 307  Acinetobacter...
ABM34089      283 DGAPVVCLLDTGVS-----AR--------------HPLIApalrgawsydea---------------------------- 315  Acidovorax ci...
WP_008239237  296 DDSTLICLLDSGVN-----HH--------------HALISpflpdhrlyaynn--------------------------- 329  Pedobacter sp...

4MZD_A        139 SDIVDKMg------HGTEVAGQITAn------gN-----------IL---GVAPGITVNIYRVFGENLskse---wvaRA 189  Lactococcus l...
P54683        432 --------------HGTHVCGSAAGtped-sswAis--------sFS---GLATDAKIA---FYDLSSgsse---ptpPE 479  Dictyostelium...
WP_000253881  312 PKYDQYQplapfneHGSLQAGLAAFgnl---mdV-----------VLensAIQLSHVIESARILPPQGnndp--llygAI 375  Salmonella en...
WP_041230105  233 ISYDPSWstvdkdgHGTNMAGIACYgdmvnileT-----------SE---PVIINHQLESVKVTPDSGknpe--ellaKI 296  Denitrovibrio...
WP_005951824  132 --------------HGSFVAGVILYgde--fsdKkwiagekikiyDA---AIVPDFSLYQLEe--------------dEL 178  Fusobacterium...
WP_004027347  322 ----EENp-----iHGLEVSSIIVNgps--fnpNlddgcgffrvrHF---GVMgqnf------------------ttfEL 369  Ureaplasma ur...
CQD03916      233 ---dprwqttpvqsHGTEMAGLALYg------dLhaa-----lvdTQ---PVQLTHRLESVKFLPDNAhndr--dlygAI 293  Mycobacterium...
WP_000273035  308 ydikpayglgaynpHGSMQAGIVIYg------dLkkc-----llsSN---SSYINHIVESGRILPPRGsnkp--nlygSL 371  Acinetobacter...
ABM34089      316 ---wgvddhglhggHGTPLAGLVLYg------dLepl-----mndSR---YVFLTHDAESMKLLPPRGfpptkppsygVV 378  Acidovorax ci...
WP_008239237  330 --awgthdtwgsegHGTGMAALALYg------dLtda-----ldsRN---SIVIRHGLESFKVKQYGVendp--elygAI 391  Pedobacter sp...

4MZD_A        190 IRRA-----ADDG--NK---VINISAGQylmis------------gsyddGTnDYQEYLNYKSAINY-----------AT 236  Lactococcus l...
P54683        480 DYSQmykplYDAG--AR---VHGDSWGSvs------------------lqGYyGGYSDDAGGIDAFL-----------YE 525  Dictyostelium...
WP_000253881  376 TVGTaykleVDRPdlNR---VYSLAVTSdhere------------sgrpsSWsAEIDQFTSGM---------------QD 425  Salmonella en...
WP_041230105  297 TMDSissieILEP--MRr-rFFCSSSTSdaslc------------vgnpsSWsGAIDQLCFGTL---------------D 346  Denitrovibrio...
WP_005951824  179 LFRLrraveEHSW--IK---IWNLAIS-------------------------------LRFAVDLERisefgllldylQE 222  Fusobacterium...
WP_004027347  370 IKKIrsiieNNQD--IK---VWNLSLG-------------------------------TKYEIKDNFisieasilddiQA 413  Ureaplasma ur...
CQD03916      294 TARAvdrpeIQAA--ARr-rVFMLAVTArrpsvdgtdtepttridtgrptSWsAAIDALAFGRAIDDsdpkltyldrdEP 370  Mycobacterium...
WP_000273035  372 TIQTankvaIANN--QIkyrIFSLAVTSennnt-------------grpsSWsGAIDKFTFGELP--------------E 422  Acinetobacter...
ABM34089      379 TQGAvsaveIERP--GAk-rIFCIACSTedlpp-------------drpsTWsGALDQIASGSMPGEasav----ptaLE 438  Acidovorax ci...
WP_008239237  392 TQMAvdlpvIIDG--QRr-rVFCLSITDaatvf------------rgrpsSWsSTIDKLCFGN---Se----------LA 443  Pedobacter sp...

4MZD_A        237 AKGSIVVAALGNdsl----niQDNQTMINFLKrfrsikvpgkvvdAPSVFeDVIAVGGID-------------------- 292  Lactococcus l...
P54683        526 YPEFSILRAAGNnel---fasLL----------------------AQATAkNAITVGAEQtahvnyvsdaleyydfsdna 580  Dictyostelium...
WP_000253881  426 GKRRLFVISAGNnld---irpDQDYWDQVNLAqi----------eDPAQAwNAITVGAYT-------------------- 472  Salmonella en...
WP_041230105  347 GHKRLFIQAAGNlhd----eeAISYPFVNLASki----------eDPCQAwNSVVIGGYTekisidddl----------- 401  Denitrovibrio...
WP_005951824  223 KYNIIICKSCGNgef---trdKEERGSIL----------------QGSDTiRSLVVASCN-------------------- 263  Fusobacterium...
WP_004027347  414 EYDVIFVVSGTNktskesknyKIG---------------------SPADSiNSLVVNAVN-------------------- 452  Ureaplasma ur...
CQD03916      371 RRPRLFLVSAGNird---lrgTDDHLARSDVEpv----------eDPAQSwNALTVGAYSnrddmsgapa---------- 427  Mycobacterium...
WP_000273035  423 NNKCLFIISAGNnrs---lnvDLNIWDQAHLAki----------eDPAHSwNSITVGTYTnlttvtdps----------- 478  Acinetobacter...
ABM34089      439 RPKRLLVVATGNvqn---gmiP----DVLTSQpl----------eDPAQSwNALTIGGFTrkdlpprt------------ 489  Acidovorax ci...
WP_008239237  444 AEQQLFIISGGNvst---akhA-DYYSLNDTTsv----------hDPAQAyNAISVGSYTsmdrfdpre----------- 498  Pedobacter sp...

4MZD_A        293 -----------------------------------------------------G-----------------YGNISDFSN 302  Lactococcus l...
P54683        581 nfqrpclfdkkycnyttakccsevsnvkglqlccpasikqnasdsfttqpqfyN-----------------ENNMGSFSS 643  Dictyostelium...
WP_000253881  473 -----------------------------------------------------EmttnddpyfegwspfamEGDVAPSSR 499  Salmonella en...
WP_041230105  402 ---------------------------------------------yhgcrviaP-----------------KGGLCPASK 419  Denitrovibrio...
WP_005951824  264 -----------------------------------------------------Q-----------------EGEVSSFSL 273  Fusobacterium...
WP_004027347  453 -----------------------------------------------------D-----------------QQEPAFYTR 462  Ureaplasma ur...
CQD03916      428 --------------------------------------------dfagyvpvaK-----------------RGELSPVSR 446  Mycobacterium...
WP_000273035  479 ---------------------------------------------mrgwslwsK-----------------HGDLCPTTR 496  Acinetobacter...
ABM34089      490 ---------------------------------------------ptglkpavP-----------------ANHRSPFSR 507  Acidovorax ci...
WP_008239237  499 ---------------------------------------------rpgwrilaA-----------------RGAMAPSNS 516  Pedobacter sp...

4MZD_A        303 I------GA---------DAIYApagttanfkkygqdkfvsqgyylkdwlftttntgwyqY----VYGNSFATPKVSGAL 363  Lactococcus l...
P54683        644 K------GPthdg--rlkPDIVApgeyitsarsngen----------stdqcgdgslpnaNglmsISGTSMATPLATAAT 705  Dictyostelium...
WP_000253881  500 Ssv---nWAwrkq-apfkPDVVAeggnrllspdrkevsn------edtvgllttsgrttgQvferGSDTSAACALVSRCA 569  Salmonella en...
WP_041230105  420 T------SStwtrrwpikPDVVFeggnlavcsdmvtka--------adlsllttshqpmkRqfdaFYATSAATAEAANFV 485  Denitrovibrio...
WP_005951824  274 S-------Gkghk-ilekPDIAMyggdvfwdpngk-------------rkvsgvysfspkGeivsSFGTSFATARMTSLL 332  Fusobacterium...
WP_004027347  463 K-------Givls-ffnkPDLAYygtcy---------------------------vfesnNkvkkVQGTSYAAAWISRKL 507  Ureaplasma ur...
CQD03916      447 TsvvfdrTKwp-----fkPDVVAdggnvavspdrtdvdt-----ppnlallttrlqrpghGfftaTRDTSAATAQVAAIA 516  Mycobacterium...
WP_000273035  497 Tsv---nWEwvkn-aplkPDFVLeggnyllsppptyad-------ahedlsilttsgdvnLpfecHRDSSAACALASNYA 565  Acinetobacter...
ABM34089      508 GsqslpsDLtp-----ikPEVLFeagnmladasgfcew-------gpsvsllstgsnvahEplvpMWATSAATGMAGHFL 575  Acidovorax ci...
WP_008239237  517 Tsll-feSQwp-----nkPDIVMeggnmitdgadiahh--------ptlqmltaskrhldQqfqlFGDTSGAAALTAKMA 582  Pedobacter sp...

4MZD_A        364 ALVVDKYGI---------------KNPNQLKRFLLMNSPEV-----------------N--------------------G 391  Lactococcus l...
P54683        706 TILRQYLVDgyfptgesveenkllPTGSLLKALMINNAQLLngtyf--------wsasStnpsnaifeqinganliqgwG 777  Dictyostelium...
WP_000253881  570 AQLTAEYPE---------------FWPETIRGLIIHSAEWT-----------------Prmmerfgllsavhspkvaket 617  Salmonella en...
WP_041230105  486 AKLTNDYPD---------------AWPETLRGLLVHSADWTeemykqaeadpsnrksdPtrmll----------rmfgyG 540  Denitrovibrio...
WP_005951824  333 GNILFWKED---------------ASALFLKAMVVQTASHgeky-------------------------------flgyG 366  Fusobacterium...
WP_004027347  508 GYLINILGF----------------SREVAKALLIHAAADSiken----------hdfSfl----------------gyG 545  Ureaplasma ur...
CQD03916      517 GNLSQAYPQ---------------LRPETIRGLIVHSAQWTdamrn-------rfnteSnktrlas------llrrygmG 568  Mycobacterium...
WP_000273035  566 AQIADKYPN---------------YWPETIRGLLIHSCQYTkamvsqyn-nliindrlSpkkaaev------llrtvgyG 623  Acinetobacter...
ABM34089      576 GRLQAALPS---------------FWPETLRALVVDSARWTepmrkkli-gtgahwktGtkkqfqa------qlrevgyG 633  Acidovorax ci...
WP_008239237  583 AEIWTAYPN---------------LWPETIRALIIHSAQYTgemtgg------fdpaeMtstqkrn------llrrfgyG 635  Pedobacter sp...
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