Conserved Protein Domain Family
Arm_2
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pfam04826: Arm_2 (this model, PSSM-Id:282656 is obsolete and has been replaced by 461447)
Armadillo-like
This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.
Links
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Statistics
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PSSM-Id: 282656
Aligned: 8 rows
Threshold Bit Score: 297.793
Created: 25-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8BHS6   112 NSDDTv-LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVK-EKALIVLNN 189 house mouse
Q6A058   529 YEIDEi-LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIK-EKALMAMNN 606 house mouse
Q6PB60   306 CKLECy-LDSPEFEKLVNILKSTTDPLIHKIAQIAMGIHKVHPFAQEFINEVGVVTLIESLLSFSSPEVSiKKAVITLN- 383 house mouse
Q3UZB0   349 CKSRTfsLEPVDFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKKY-PRTLN-INA 426 house mouse
Q5RDG2   300 CKSRGfsLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVSNPNVKEH-PRALSMVDD 378 Sumatran orangutan
Q8N2F6    87 GSYDDv-LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQSIK-EKALNALNN 164 human
AAI61555  81 vsasvsdLQPHHLANLLDILVTSSDSSLQEKVLITLCNSAAFSANHDIIRSLGGITIIAKSLSDSSEQIK-VNALNALNN 159 western clawed frog
CAG03393  83 haSSGn-LEPQHLKVLLSRLQSSGDPAESQRILLTLGNAAAFTVNQNLIRDYEGIGTIAAFLSDPAAEVR-VQTLNALNN 160 spotted green puffe...

Q8BHS6   190 LSVNAENQRRLKVYMNQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHILANSISDFFRLFSAGNEETKLQVLKLLLN 269 house mouse
Q6A058   607 LSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSN 686 house mouse
Q6PB60   384 -SSGDDRYNKVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVVSYFSELFHLLSQGNRKTRNLVLKVFLN 462 house mouse
Q3UZB0   427 NPDAPEEVKETEAHVNKVCRDILCCPLNCSVQVEELKLLVSLSVKFDYHHVVIYYVRYFISLLNKGSVKIKFQILRVLLC 506 house mouse
Q5RDG2   379 SSESSEGPKSGESYIHQVCKGILSCPMNSPVQLAGLKLLGHLSVKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSC 458 Sumatran orangutan
Q8N2F6   165 LSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTKVQVLKLLLN 244 human
AAI61555 160 LSMNVQNQELIKDYINQTCSAISLSSLNSEVQLAGLRLIINMSVTDNYHNMVADHLPCFLYLLAEGNNIIQIYTLKVLVN 239 western clawed frog
CAG03393 161 LSMNVRNQDQIKVCVPQVLELIEVSPVNSELQLAALRLLTNLSVTDQHQHLFKTSIRLLLSLLVVGNEEL---------- 230 spotted green puffe...

Q8BHS6   270 LAENPAMTRELLRAQVPSSLGSLFNKKEYKEVILKLLIIFENINDNFKWEenEPAQNHFSEGSLF-FFLKEFQVCADKVL 348 house mouse
Q6A058   687 FAENPDMLKKLLGTQVPSSFSSLYNSYVESEILINALTLFEIIFDNLRAE--VFNYREFNKGSLF-YLCTTSGVCVKKIR 763 house mouse
Q6PB60   463 MSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGsiVVV-DHLSYNTLT-AIFREVK------- 533 house mouse
Q3UZB0   507 LSKNQANTRELISAEVMSSLVALFHKNESKANILHIIEIFENINFQFKKRakLFTKEMFTKSELI-SIFREAKEFDQKLQ 585 house mouse
Q5RDG2   459 LSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQVKTKakLFTKEKFTKSELI-SIFQEAKQFGQKLQ 537 Sumatran orangutan
Q8N2F6   245 LSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEghLAVQPTFTEGSLF-FLLHGEE-CAQKIR 322 human
AAI61555 240 LSANPTMTQTLLTAKGSQSLTSLFDSRVDREILVRVLIFAANLSKHLGSGhgYDLHANYNEDCLFnLLYGDSSPLQKDIT 319 western clawed frog
CAG03393 231 --------------QAPASVLLLFDAQTASPVLLRLLTFAGNL-RAWRPSaqVAHLLRQTQDCLFrVMLDESSQLNGRLF 295 spotted green puffe...

Q8BHS6   349 GIESRHDFQVRVKVG 363 house mouse
Q6A058   764 ALANHHDLLVKVKVI 778 house mouse
Q6PB60   534 ------------GII 536 house mouse
Q3UZB0   586 DLTDHSDPDVRDKVI 600 house mouse
Q5RDG2   538 DLAEHSDPEVRDKVI 552 Sumatran orangutan
Q8N2F6   323 ALVDHHDAEVKEKVV 337 human
AAI61555 320 ALFQYPDVEVKEQVV 334 western clawed frog
CAG03393 296 RLLSHPDGEIQAQVa 310 spotted green pufferfish
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