2DAJ


Conserved Protein Domain Family
Cobl

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pfam09469: Cobl (this model, PSSM-Id:286545 is obsolete and has been replaced by 462810)
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Cordon-bleu ubiquitin-like domain
The Cordon-bleu protein domain is highly conserved among vertebrates. The sequence contains three repeated lysine, arginine, and proline-rich regions, the KKRAP motif. The exact function of the protein is unknown but it is thought to be involved in mid-brain neural tube closure. It is expressed specifically in the node. This domain has a ubiquitin-like fold.
Statistics
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PSSM-Id: 286545
Aligned: 4 rows
Threshold Bit Score: 139.201
Created: 21-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2DAJ_A          8 EKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKCEFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVN---- 83   human
O75128        152 EKSVRLVVNYLRTQKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNR---- 227  human
AAI67934      148 EKTVRLVVNFLGTQKTVVRVSPEVPLQNIVAAICEKCEFQLEDVILLRDTTSKEELDMAKSLKVLGIKELYAWNSK---- 223  western clawe...
XP_010748793  145 EKTVRLMVNYHSSQKAVVRVNPLVPLKALIPVICDKCEFDSAHVLLLKDSISRHELPLDRSLTELGIKELYVHDQSlvlq 224  large yellow ...
2DAJ_A         84 ---------RES 86   human
O75128        228 ---------RET 230  human
AAI67934      224 ---------QEK 226  western clawed frog
XP_010748793  225 pkmasapalNYS 236  large yellow croaker
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