Conserved Protein Domain Family
KASH_CCD
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pfam14662: KASH_CCD (this model, PSSM-Id:291334 is obsolete and has been replaced by 405365)
Coiled-coil region of CCDC155 or KASH
This coiled-coil region is found in the central part of KASH or Klarsicht/ANC-1/Syne/homology proteins. KASH are a meiosis-specific proteins that localize at telomeres and interact with SUN1, thus being implicated in meiotic chromosome dynamics and homologue pairing.
Links
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Statistics
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PSSM-Id: 291334
Aligned: 8 rows
Threshold Bit Score: 212.434
Created: 29-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5RHB5        347 LETSDLVFCVADLQLNNQKLQEEVRKLKQAVENMEDTNQKLIEENEELKTQAKMGQQLLQKEKMLKEEVEEMKLSLTSSE 426  zebrafish
Q6ZRK4        237 QATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLE 316  human
Q8N6L0        157 QATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLE 236  human
Q2T9R2        157 PATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEISALRKQLRSTQQALQLARGVDEELEDLKTLAKSLE 236  cattle
XP_005664781  157 PATADLLSSLEDLELSNRRLAGENAKLHRSVETAEEASARLGEEILALRKQLRSTQQALQFAKAMDEELEDLKTLAKSLE 236  pig
XP_006223341  197 PATAELLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEITALRKQLRSTQQALQVAKALDEELEDLKTLAKSLE 276  Norway rat
XP_011221520  157 PATAELLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEIEALRKQLRSTQQALQCAKAVDEELEDLKTLAKSLE 236  giant panda
XP_001633265   57 DRAQEMMATIESLQANNKRLLDQYSSVQAQMDLTDELNAQLTAELTDLKKQMQILQHTSEKYKLLEKENADLRQSVSETQ 136  starlet sea a...

Q5RHB5        427 ESRAQAAAQRKQMERENQSLISKIAALQEENMKVTLEAEELQKKMNDLCDLNADLQVQIHSFDAILADKESLIQEKNKQM 506  zebrafish
Q6ZRK4        317 EQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDV 396  human
Q8N6L0        237 EQNRSLLAQARQAEKEQQHLVAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDV 316  human
Q2T9R2        237 EQNRSLLAQARHTEKEQQRLVAEMETLQEENGKLLAERDGVKRRSEELASEKDILKRQLYECEHLICQRDAILSERTRHA 316  cattle
XP_005664781  237 EQNRSLLAQARQTEKEQQHLVAEMAILQEENGKLLAECDGVKRRSEELATEKDALKRQLYECERLICQRDAILSERTRHA 316  pig
XP_006223341  277 EQNRSLMAQARHTEKEQQHLVAEVETLQEENGKLLAERDGVKRRSEELATEKDALKRQLCECERLICQREAALSERTRHA 356  Norway rat
XP_011221520  237 EQNRSLLAQARQTEKEQQHLVAEMETLQEENEKLLAERDGVKRRSEELATEKEALKRQLYECERLICQRDAVLSERTRHA 316  giant panda
XP_001633265  137 EVANSLQNRNSLLEREKQSLEENIQDLNVKLTQSQSEISLLASQKKEL-TESIGLQKQVV-FEELKNVREEFAEESTTKT 214  starlet sea a...

Q5RHB5        507 DELKVAVVEYSSVTELLRADKNKLESQMQMMQ 538  zebrafish
Q6ZRK4        397 ESLAQTLEEYRVTTQELRLEISRLEEQLSQTY 428  human
Q8N6L0        317 ESLAQTLEEYRVTTQELRLEISRLEEQLSQTY 348  human
Q2T9R2        317 ESLTKTLEEYRATTQELRLEISHLEEQLSQTQ 348  cattle
XP_005664781  317 ESLAKTLEEYRTTTQELRLEISHLEEQLSQTH 348  pig
XP_006223341  357 ESLAQTLEEYRTTTQELRQEISNLEEQLSQSQ 388  Norway rat
XP_011221520  317 ESLAETLEEYRTRTQELRLEISHLEEQLSQTH 348  giant panda
XP_001633265  215 QYLNSVIAELTLANEELKLEKSRLEQVVADLT 246  starlet sea anemone
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