O88700 1 MAAVPLNNLQEQLQRHSARKLNNQPSLSKPKSLGFTFKKKTSEG-DVSVTSVSVVK-TPALSDKDVNVSEAFSFTE-SP- 76 house mouse XP_008273542 1 MAAVPQNNLQEQLELHSARKLHNRLNLSKPKSSGFTFKKKASSGnSASVTSVSAAR-TPVLSDKDVNVTEGSSFSE-PQ- 77 rabbit XP_004852872 1 MAAIPLNNLQEQLERHSARKLNNKSDLSKPKPCGFTFKKKTTSDnDASVTSVSIAK-TPVLSDKDVNVSEVFSFTE-PP- 77 naked mole-rat XP_012669021 1 MAGLPHNNLQEQLERHSARKLNNKLSFSKPKSLGFTFKKKTPSDnSISLTS---------MSD---NVTEAFSVSE-PP- 66 small-eared g... XP_008757811 10 MAAVPLNNLQEQLQRHSARKLKNQFSISKPKPSGFTFKKKTPEG------DVSVVR-TPVLSDKDVNMSEALSYTE-PP- 80 Norway rat ERE79885 6 MAAVPLNNLQEQLQRHSARKLNNKFDLSKPKSSGFTFKKKTSEG-DVSVTSVPVVK-TPALSDKDVIVSEAFPSTEsPL- 82 Chinese hamster XP_012397779 1 MAIIPQNNLQQQLERHSAKEIQNKLNVLKHKSTGFTFKKKIPS-------SSSVTQ-AFVLSDKDVNITENVPLSK-PL- 70 Tasmanian devil XP_007479356 1 MAVIPQNNLQQQLERHSAKEIQNKLNVLRPKSTGFTFKKKIPPGn-------SVTH-APVLGDKDVNVTETFPLSK-AF- 70 gray short-ta... XP_007666291 1 MAALPQNNLQQQLERYSAKETHNKLSLQKPKSTGFTFKKNLSPGsSVSAACLKVPNtTAALRDKDVNSTTASSLG----- 75 platypus XP_005999763 1 MTAVPQNNLQKQLELHSAKGAQNKLSLSKSKPGGFTFKKKTPPGnNDATTFSEVKL-TNVLKDKDVNIHENISLAK-PLt 78 coelacanth
O88700 77 LHKPK---QQAKIEGFfKHFPGRQQ--SKGTCSEPSL---PATVQtaqDTLCTTP---KTPTAKK-L------PVAVFKK 138 house mouse XP_008273542 78 ACPAG---PPARINDFfKNAPAGLQ--SRGAGSTPLL---PDVSQtpqEASCTPR---LAPAAKT-P------RDTVFKK 139 rabbit XP_004852872 78 PHTPS---QQPRINGFfKNAAVGQQ--GQRTGSKLLL---TGLLQipqEALPTTQ---NISAVKK-P------HNAILKK 139 naked mole-rat XP_012669021 67 SHTTN---QQTKINDFyKNAPAGQQ--TQRVGSKPLL---PDLVQipkEVLCTTP---HTSVIKK-P------SDAAFKK 128 small-eared g... XP_008757811 81 LHKPK---QQSNIDGFfKNSPGGQQ--SKETCSELSL---PEVVQipqDASCTTP---KTPAVKK-P------HVAIFKK 142 Norway rat ERE79885 83 LHTPK---QQPGIDGFfKNSLGEQQ--TK--GTKPSQ---LDLVQipqEVLCTAP---KTPAVKK-P------HISVFKK 142 Chinese hamster XP_012397779 71 PNTKN---QQASITASsEKTSKGQQ--IHKFCSNQIL---SDSSKnthETSCYLQpstNENSVKK-V------LCKDSKK 135 Tasmanian devil XP_007479356 71 FNAKN---QQTSISDSsEKTSKAQQ--IQKFCSNQIL---LNSSKntqETSKVSQpptKENCVKK-E------LCKDSKI 135 gray short-ta... XP_007666291 76 ---GN---QQRRIGGFfEKSLKNEE--TQPLGTDRAG---SSSRKtqtAVSRGSQppaKGMTITPdP------PDIVSKR 138 platypus XP_005999763 79 SSLTKhndQQLKIGHFfEKNCKSQPqvTQMFSGQPFLncsESVRQtskILPVFTR---PEETIKE-PkqpsakPEESSKK 154 coelacanth
O88700 139 LEFSSSADS---LS----------DWAD------MDDFDMSA-S--DAFASLAKNPA-TRVSTAQK------MKKTKRNF 189 house mouse XP_008273542 140 LDFSSSLDSlgaLN----------GWDD------MDDFDTSGtP--KAFAASPRKPV-ARVSTAQK------SKRAKRNF 194 rabbit XP_004852872 140 LEFSSSSDSfhtMN----------DWDD------MDDFDTSEtS--KVFATPPKNHL-VRVSTAQK------SKKAKRNF 194 naked mole-rat XP_012669021 129 LDFSSSSDSfgaID----------NWDD------MDDFDTSGtS--KAFVTPLKNHFlLRVSTAQK------SKKAKRNF 184 small-eared g... XP_008757811 143 LEFSSSADS---LS----------DWAD------IDDFDVPA-S--DAFVSLTRNPT-TRVSTAKK------LSSSKRNF 193 Norway rat ERE79885 143 LEFSSSPDS---LN----------DWAD------MDDFDISA-S--DAFVSMSRNPV-IRVSTAQK------PKKSIRNF 193 Chinese hamster XP_012397779 136 LELNSSFDStslVS----------DWDD------IDDFDTSGnS--KTFTTPSRSNF-AKLNSTQR------SKGDKNNL 190 Tasmanian devil XP_007479356 136 LETNSSFDSi-lVN----------DWDD------IDDFDTSGnS--KTFTTPSRTHF-TKLNNTQR------SKTDKNNL 189 gray short-ta... XP_007666291 139 LDFSSALDTilsLD----------DWDD------LDDFDTSGkNcpKAFVTPPSSQA-VKAGRTPV------SSR-KDDA 194 platypus XP_005999763 155 SELDCSFSTvisIEdwddlddfdtSWKDkkssqtISPPDKVRqA--KHYKSTPSSHQ-SKINLSSGtfndslSTRNSKNV 231 coelacanth
O88700 190 FKPPPRKANAVKTD---LTPPSPECLQVDLT-----------KESEeeeeeeeeaEGAD-------CLSRDVICIDND-- 246 house mouse XP_008273542 195 CKAQLKKADAAEAD---LTPASAASKPVELA-----------GAGK---------GDCD-------GVGGGVICIDDDdg 244 rabbit XP_004852872 195 FKAQPHKTNTVKAD---LTPS--ESQPVDLT-----------KEEK---------DDSE-------WLKSGVICIDDD-- 240 naked mole-rat XP_012669021 185 SKEQLYKTDTVKAG---LTTSSSENKQVDFT-----------KGQK---------DDSE-------RLSSDVICIDDD-- 232 small-eared g... XP_008757811 194 FKPPPR-ASAVKAD---LTPSSPECLQVDLT-----------KEQE---------EEAD-------CLSRDVICIDTD-- 240 Norway rat ERE79885 194 FKPPPHKASVVKAG---LTLSSPESSQVDLT-----------KDQK---------DESE-------YLSGDVICIDSD-- 241 Chinese hamster XP_012397779 191 SKTRARKANGKKVDpelLNFPSGKNKQAELI-----------KKEL---------PESE-------ELSSPMICLDDD-- 241 Tasmanian devil XP_007479356 190 SKTQ---TSGKKIDpelLNFPSGKSRQVELT-----------RKEL---------PESE-------ELNSPVICLDDY-- 237 gray short-ta... XP_007666291 195 SNARVSKAKTGKVGvelVEPRPGGGDRVART-----------SDPL---------REPE--------PSGDSVIYADT-- 244 platypus XP_005999763 232 LSPQKSIQDTMDKDnqvGYANSFEISERSLTcvdlvslnstgKDCN---------DAAEvpaakkkSLSTGSVVIDEE-- 300 coelacanth
O88700 247 SASEELTEKDTQESQSLKAHLGAER-----GDSEKKSHE---------------DEAVFHSVQNTE---YFEHNDNDYDI 303 house mouse XP_008273542 245 PVSQVLI-LDSQESHSLETHLGGER-----DHPEDKKVL---------------DTVELHSAEEVP---CIELEDDDYDI 300 rabbit XP_004852872 241 SIPQVHTDEDTQERHSLKIHLGDER-----DNNEKH-NE---------------EDVELLSSEKAT---CVELNDDDY-I 295 naked mole-rat XP_012669021 233 CISEVRINEDTQESHSLKTHLGDER-----DNSGKKKNL---------------EDTELHSTEKIP---YTKLS-DDYDT 288 small-eared g... XP_008757811 241 PASEELLEKDVQEGLSLDARLGTER-----VDSAKKSHE---------------DKAAFQSPQNAL---YFEHNDNDYDI 297 Norway rat ERE79885 242 PGSEELVKKDAQESQSLETELEVER-----DNSEKKNHV---------------GEVKLQSTEKAL---YDDDDDY--DV 296 Chinese hamster XP_012397779 242 PISEEFKNEDIQEKQALKTQLDDER-----DYSEKKKSP---------------ERVEQHTIDESLganCEEFNEDDFDI 301 Tasmanian devil XP_007479356 238 V-SEEVRNEDIQESHASKTHLCKER-----DDNEKKKYP---------------NGTEQHAADESLgadFAEFNEDDFDI 296 gray short-ta... XP_007666291 245 ADSRGIPAEDVQEVRSFEAISHDEReknhtDDREKEQNSeeiefpegeedcchvQESDSGWDEKPL---VGVIEEDDYDV 321 platypus XP_005999763 301 ------ETNCIKENERRDS----ET-----QNRELKWRE---------------TDGDSNLVHQSNe--NFVFENDDFDI 348 coelacanth
O88700 304 DFVPPSPEE-II--STASSSLKCSSMLKDLDDSDKEKGILSTSEElLSKPEEMTTHKSDAGTSKDCDAQQI 371 house mouse XP_008273542 301 DFVPPSPEEeVS--SATSSSLKCSSMLKDLDTPHREKDVLSPAQDlLSKPEKLTPQEPDPETTAGCEARPS 369 rabbit XP_004852872 296 DFVPPSPEEeSI--SASSSSLKCFSALKDLDASDQEEDVLSTSKDlLSKPEKMTTQEPNPEISTDCDARQI 364 naked mole-rat XP_012669021 289 DFVPPSPEEeSI--STASSSLKCFSMLQDSDNFDREKDVLSISKDtLSKPEKITAQEPNPETSTDYDARQI 357 small-eared galago XP_008757811 298 DFVPPSPEE-II--STASSSLKCSSMLKDLDDSDKEKDILSTSKD-LSKPEEMTTPKSDLGTNEDCDAQQT 364 Norway rat ERE79885 297 DFVPPSPEEeII--SAASSSSKCCSMLKDLDDSDKEKDILNTSKDlLSKPEEMPAKEPDPGTNTDCDDKQM 365 Chinese hamster XP_012397779 302 DFIPPSPEEgVF--S---SSLRYLCTLKEPSICDEGKNATKLSNYfSSESEKTTSPQLLQETSTKYDGKLL 367 Tasmanian devil XP_007479356 297 DFIPPSPEEeVFspSSCSSSLKYFSTLKESSTCDKEKNGTKLSDDfLSESEKTTSLQPIQETSTKHDGKLL 367 gray short-tailed opossum XP_007666291 322 DYVPPSPEEeVLssCSSSASLKRISVLKESAIYSGRRTTPDESNv-LSNPKRTTSEERKIETAMERDDKQp 391 platypus XP_005999763 349 DFIPPSPQDpMS--SPSFIQHK--SNLKQSTCCSEGLLGMTISDPvISEHNQDILRQPPQWSNSNREAEAF 415 coelacanth
Jiyao W et al.(2023). "The conserved domain database in 2023.",