2KNC,4UM8


Conserved Protein Domain Family
Integrin_b_cyt
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pfam08725: Integrin_b_cyt (this model, PSSM-Id:312304 is obsolete and has been replaced by 462580)
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Integrin beta cytoplasmic domain
Integrins are a group of transmembrane proteins which function as extracellular matrix receptors and in cell adhesion. Integrins are ubiquitously expressed and are heterodimeric, each composed of an alpha and beta subunit. Several variations of the the alpha and beta subunits exist, and association of different alpha and beta subunits can have different a different binding specificity. This domain corresponds to the cytoplasmic domain of the beta subunit.
Links
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Statistics
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PSSM-Id: 312304
Aligned: 66 rows
Threshold Bit Score: 51.4005
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2KNC_B         37 TIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITY 76   human
XP_002424702  715 DFYDKREYEKFEREKHLAQWGKGENPLFKTPTKRYENPTY 754  human body louse
XP_004349803 1020 gMRDRREWGKFEAEREKSRWKGDDNPLFKASTTEYSNPLY 1059 Capsaspora owczarzaki ATCC 30864
XP_009861622  371 TNYDKRKWEEFQAEVKKSKWTESNNPIHREAKQTFVNPRF 410  vase tunicate
XP_004346743 1011 MLMDKREWQKFEQGRQASQWKSDNNPLFQSSVKETENPLY 1050 Capsaspora owczarzaki ATCC 30864
XP_011403709  259 VYKDHREYKNFLSEINRSKGSAQENPTYLKPIIETVNPAY 298  Amphimedon queenslandica
XP_011409775  745 mllDYMEVKKFMAEVQDPKFRKNENPLFESPNKEYKNPTY 784  Amphimedon queenslandica
XP_011403560  718 iMKDKRELKKFQSEVNDAAWADTANPLYVTPITDYQNVAY 757  Amphimedon queenslandica
XP_003383731  770 ilaDRAEWKKFEKEVAETDLSKNFNPLYHSPAVKYDNIAF 809  Amphimedon queenslandica
XP_011403708  942 VYKDHREYKNFLSEISRSKGSAQENPTYLKPIIETVNPAY 981  Amphimedon queenslandica
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