Conserved Protein Domain Family
Sox_N
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pfam12444: Sox_N (this model, PSSM-Id:315171 is obsolete and has been replaced by 463586)
Sox developmental protein N terminal
This domain family is found in eukaryotes, and is typically between 69 and 88 amino acids in length. The family is found in association with pfam00505. There are two conserved sequence motifs: YDW and PVR. This family contains Sox8, Sox9 and Sox10 proteins which have structural similarity. Sox proteins are involved in developmental processes.
Links
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Statistics
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PSSM-Id: 315171
Aligned: 25 rows
Threshold Bit Score: 76.6245
Created: 27-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q70W02       115 SAVAVARAAATLLESKSseeenydeslmNTGSSAR-SASPGTNd------------DLSDRDSNPEKD------DM---- 171 vase tunicate
XP_786809      2 SSPESLELHHSLSEGSSpr--------tPGSDSDD-ASSECSRe------------DLAILSSRVDPSslvvgpEG---- 56  purple sea urchin
XP_001373727  21 tTSSMSHVEDSDSDTPLs----------PAGSEGL-GCSSGTGprs--------agGGAALGSKVDPG------EV---- 71  gray short-tail...
XP_014792165  21 ttSSMSHV-DSDSDSPLs----------PAGSEGL-GCAPAPApr---------ppGAAPLGAKVDAA------EV---- 69  Philomachus pugnax
AAH43704      18 TASSMSHVEDSDSDAPPs----------PAGSEGL-G--------------------RAGGGGRGDTA------EA---- 56  house mouse
XP_002932315  21 TASSMSHVSDSDSDSPLs----------PAGSEGR-GSHRp---------------PGISQLSKRDGE------ET---- 64  western clawed ...
XP_007556432  22 TNSSMSQD-ESDSDAPSs----------PTGSDGH-GSLL------------------SGLGKKLDSE------D----- 60  Amazon molly
NP_001158342  22 TNSSMSQD-ESDSDAPSs----------PTGSDGH-GSLL------------------AGLSKKLDSE------D----- 60  Japanese medaka
XP_003224717  23 PSPALSDEEASSSGSPC-----------PSGSGSD-AEGSGSSshggrpprlgdggAFAKSGDAEMKK------EAggvg 84  green anole
XP_002122233 130 savavaraaaTLLESKSseeenydeslmNTGSSARsA-SPGTNd------------DLSDRDSNPEKD------DM---- 186 vase tunicate

Q70W02       172 ------SKD-----IKDAVSQVLKGYDWTLVPMPVR 196 vase tunicate
XP_786809     57 ------TAAqfspsIRDAVSRVLNGYDWSVVAIPSR 86  purple sea urchin
XP_001373727  72 -------DDrfpacIRDAVSQVLKGYDWSLVPMPVR 100 gray short-tailed opossum
XP_014792165  70 -------DErfpacIRDAVSQVLKGYDWSLVPMPVR 98  Philomachus pugnax
AAH43704      57 ------ADErfpacIRDAVSQVLKGYDWSLVPMPVR 86  house mouse
XP_002932315  65 ------MDErfpacIREAVSQVLKGYDWSLVPMPVR 94  western clawed frog
XP_007556432  61 -------DErfpacIRDAVSQVLKGYDWSLVPMPVR 89  Amazon molly
NP_001158342  61 -------DErfpacIRDAVSQVLKGYDWSLVPMPVR 89  Japanese medaka
XP_003224717  85 ggggggEEDkfpvcIREAVSQVLKGYDWTLVPMPVR 120 green anole
XP_002122233 187 ------SKD-----IKDAVSQVLKGYDWTLVPMPVR 211 vase tunicate
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