Conserved Protein Domain Family
DUF4174
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pfam13778: DUF4174 (this model, PSSM-Id:379363 is obsolete and has been replaced by 463980)
Domain of unknown function (DUF4174)
This domain of unknown function is found in a putative tumor suppressor gene and in a ligand for the the urokinase-type plasminogen activator receptor, which plays a role in cellular migration and adhesion.
Links
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Statistics
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PSSM-Id: 379363
Aligned: 89 rows
Threshold Bit Score: 69.1994
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
tigr:ACP_3463                       40 LAEMKNCWRPLLVFSp-SDTDARLKQQEQMLDADADDMMDRFVLFTPI-------VPRAKQVPTPLdaPWtllAENQMQA 111 Acidobacterium capsulatum ATCC 51196...
jgi:Ftrac_0096                      11 LDDFQWKNRLLIIYTa-DQKSTQLDKQLAEITRNKEGYNERDLKVIILknqkveiWNSNKN------------HLLDFHQ 77  Marivirga tractuosa DSM 4126...
kribb:DDD_1844                       7 IEKHRWENRILLVISeeNNSNEEYSNQLQVINDSLEGYTERKLIVYTV-------LPNKYRLLG-----I---TTNQEAN 71  Nonlabens dokdonensis DSW-6...
WGS:AAXU:1101174000285_ALPR1_16159  24 LSEHRWKDRLVILQAn-DLNNQLLKEQILELRNNNEGLKDRQIIVYQI-------IQNKYQK-----------GIYDENE 84  Algoriphagus machipongonensis...
SDU:ZPR_4594                        22 NDSYLWENRLVLMLTn-SIENSDFKEQLGEFRNKEEELEDRKIVVYQV-------TPKKYAT-----------GISDTPD 82  Zunongwangia profunda SM-A87...
jgi:Murru_2084                      26 LEKHKWTNRILIVKTl-DVQSKKYKEQVKEFTNSTEELIDRKLILYKI-------VNNDFTL-----------TNYTNSS 86  Muricauda ruestringensis DSM 13258...
EAQ40664                            21 FKKHQWKNRVLIVSTi-DDTSSDFLKQIDLLKNLNQELKERKLIIYQI-------VNDKYKV-----------G--FSSN 79  Polaribacter sp. MED152...
CAL68059                            22 LSEYKWKNRLIVVFS----DSEKLEKQLYEFKNEAKAFQERKLIVIQ--------AAPKTSRILMP--EM---SGWQDSN 84  Gramella forsetii KT0803...
jgi:Celal_2299                      26 ISDFKWKNRVLLLVDt-ELNSENIKQQIKVFEGLHDAFQERDIIYFII-------TSKG--------------SYDSDKQ 83  Cellulophaga algicola DSM 14237...
jgi:Cycma_3401                      22 IKDLQWKNRVLLVFp--ADKNAKGLGLTD---AIQVDLVDRDLIYFY--------FGDEFESNS-----PytfTKNYQKE 83  Cyclobacterium marinum DSM 745...

tigr:ACP_3463                      112 VREKFHV---------PVNR-FE-VMLLGEDGKPK-LVRDVPIATGELNALIDTMPRRKLE 160 Acidobacteri...
jgi:Ftrac_0096                      78 IIKELNI---------EEKQpLQ-NLLIGKDGGVK-LKSNSTISNEKLFRIIDAMPMRQRE 127 Marivirga tr...
kribb:DDD_1844                      72 WIKNSKLyst----ynENKKpFK-VVLIGLDGGVK-EERNAAISSEELFAIIDGMPMRRSE 126 Nonlabens do...
WGS:AAXU:1101174000285_ALPR1_16159  85 WVKSEGKfts----hnEGDSpFQ-FTLIGLDGGIK-LKNNEPISCEKLFGTIDQMPLRQSE 139 Algoriphagus...
SDU:ZPR_4594                        83 WNKGDNFyek----fkKSNTpFE-IILIGLDGGTK-MRKKEFIPADEIFEKIDSMPLRRAE 137 Zunongwangia...
jgi:Murru_2084                      87 LNSSGKVsgklaenilDAKEnFE-IILIGLDGGIK-IQQTKILTKEHLFNTIDAMPMRKNE 145 Muricauda ru...
EAQ40664                            80 FNSSNSIskk----yvNTKKgLQ-IILIGLDGGVK-LKQNYVLTAEKLFAIIDGMPMRKRE 134 Polaribacter...
CAL68059                            85 LYQEMKL---------EKKTdFE-IILVGLDGEVK-LRQQKLLETKKLFDFIDSMPMRQSE 134 Gramella for...
jgi:Celal_2299                      84 LLNLKGLe-------tYYHKdFSgLILLGKDGGIK-LKTPFIVTAKTIISLIDSMPMRQSE 136 Cellulophaga...
jgi:Cycma_3401                      84 LQKLYGS---------GSDK-GN-YVLIGKDGGSKlEEFGNEINWQLLFSTIDSMPMRIRE 133 Cyclobacteri...
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