1ZT3


Conserved Protein Domain Family
Thyroglobulin_1

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pfam00086: Thyroglobulin_1 (this model, PSSM-Id:395039 is obsolete and has been replaced by 459665)
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Thyroglobulin type-1 repeat
Thyroglobulin type 1 repeats are thought to be involved in the control of proteolytic degradation. The domain usually contains six conserved cysteines. These form three disulphide bridges. Cysteines 1 pairs with 2, 3 with 4 and 5 with 6.
Statistics
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PSSM-Id: 395039
Aligned: 185 rows
Threshold Bit Score: 49.2146
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1ZT3_A          5 CRIELYRVVESLaka---qetSGEEI---SKFYLPNCN-KNGFYHSRQCETsmDGeaGLCWCVYPWnGKRI-PGS-PEIR 75   human
EDS31286      248 QARMLSELLS-----------VNERE---GRGYVPQCDgPGGSFSTRQCSR--NG--LVCWCVDPKnGNKI-KGT-MGAA 307  southern hous...
EFN66575      339 RDRMLAEILS-----------VSERQ---GRGYVPQCR-EDGGFETRQCSR--NG--LVCWCVDDE-GRKI-SGS-MGPS 396  Florida carpe...
XP_001606712  333 RNRMLAELLS-----------ISERQ---GRGYVPQCS-EDGEYERRQCSR--NG--LVCWCVDAL-GQKV-SGS-MGPA 390  jewel wasp
XP_012824754   88 CRLMHLEMLHKSrsershpgrDRLEV---DNVYDPECE-ESGAFKAKQCDE--DS--NQCWCVDSA-GVRV-TDK-TSDD 156  tropical claw...
XP_004752925   74 CLVMKAEMTSSKsgrrvrpegAFQNN---DGLYDPDCD-EKGLFKAKQCNG--TT---TCWCVNTA-GVRR-TDKdNEEE 142  domestic ferret
XP_002195947   27 CLLMKAEVMGSKsgrrekpkdAFEDT---DGLYDPECE-NNGTFKAKQCNG------STCWCVNTA-GVRR-TDK-HDTD 93   zebra finch
XP_002810812   73 CLLLKARMSAPKnart-lvrpSEHALvdnDGLYDPDCD-PEGRFKARQCNQ---T--SVCWCVNSV-GVRR-TDK-GDLS 142  Sumatran oran...
XP_015206106   86 CRLMHLEMLNKRrtg---tilPGGRL---DIEYDPECD-GSGMFKPKQCDD--DS--NLCWCVDSA-GVRV-TDK-TGDD 151  spotted gar
XP_011676765 1142 CQARYDTVMAKLk--------NNPPR---NGFYVPQCD-EEGNYRTVQCLY--PQ--DACWCANPItGRRLrKATyTGDT 1205 purple sea ur...
1ZT3_A         76 GDPNC 80   human
EDS31286      308 QMVNC 312  southern house mosquito
EFN66575      397 KKIDC 401  Florida carpenter ant
XP_001606712  391 EKVDC 395  jewel wasp
XP_012824754  157 --PKC 159  tropical clawed frog
XP_004752925  143 --ISC 145  domestic ferret
XP_002195947   94 --LKC 96   zebra finch
XP_002810812  143 --LRC 145  Sumatran orangutan
XP_015206106  152 --PKC 154  spotted gar
XP_011676765 1206 --PSC 1208 purple sea urchin
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