4F4J,2ANC,3TVT,1KJW,3NEY


Conserved Protein Domain Family
Guanylate_kin

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pfam00625: Guanylate_kin 
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Guanylate kinase
Statistics
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PSSM-Id: 395500
Aligned: 11 rows
Threshold Bit Score: 202.226
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4F4J_A  16 MSRPIVISGPSGTG---KSTLLKKLFAEYPDSF-G-FSVPSTTRTPRAGEVNGKDYNFV-SVDEFKSMIKNNEFIEWAQ- 88   Saccharomyces cerevi...
P46195   3 GPRPVVLSGPSGAG---KSTLLKKLLQEHGSIF-G-FSVSHTTRDPRPGEENGKDYYFV-TREVMQRDIAAGDFIEHAE- 75   cattle
P44310   3 QGNLYILSAPSGAG---KSSLISALLASDSSTQ-KmVSVSHTTRAPRPGEVEGVHYYFV-SKEEFESLIEQDLFLEYAKv 77   Haemophilus influenz...
2ANC_F   3 qGTLYIVSAPSGAG---KSSLIQALLKTQPLYD-TqVSVSHTTRQPRPGEVHGEHYFFV-NHDEFKEMISRDAFLEHAE- 76   Escherichia coli
3TVT_A  99 YTRPVIILGPL------KDRINDDLISEYPDKF-G-SCVPHTTRPKREYEVDGRDYHFVsSREQMERDIQNHLFIEAGQ- 169  fruit fly
1KJW_A 104 YARPIIILGPT------KDRANDDLLSEFPDKF-G-SCVPHTTRPKREYEIDGRDYHFVsSREKMEKDIQAHKFIEAGQ- 174  Norway rat
P54936 773 RRKTLVLLGAHGVG---RRHIKNTLIHRHPNRF-A-YPIPHTTRPPRKDEVDGKHYYFV-TNEQMMADIQNNEYLEYGT- 845  Caenorhabditis elegans
P49697 282 KRKTLVLIGAPGVG---RRHIKNVLLTKYPEKF-S-YPVPHTTRPQRKGDANGEEYFFI-SNEAMTKCISANELLEYGS- 354  torafugu
3NEY_B  18 gRKTLVLIGASGVG---RSHIKNALLSQNPEKF-V-YPVPYTTRPPRKSEEDGKEYHFI-STEEMTRNISANEFLEFGS- 90   human
Q02641 228 SMRPIILVGPSLKGyevTDMMQKALFDFLKHRFdGrISITRVTADISL------------AKRSVLNNPSKHIIIERSNt 295  human
O01661 198 SMRPVVLVGPSLKGyevTDMMQKAVFDYLKHRFeGrIIITRVTADISL------------AKRSLLNNPNKRAMMERANs 265  Caenorhabditis elegans
4F4J_A  89 FSGNYYGSTVASVKQVSKSGKT---CILDID-MQGVKSVKAIpELNARFLFIAPPSVEDLKKRLEGRGTETEESINKRLS 164  Saccharomyces cerevi...
P46195  76 FSGNLYGTSKAAVRAVQAMNRI---CVLDVD-LQGVRNIKKT-DLRPIYIFVQPPSLDVLEQRLRQRNTETEESLAKRLA 150  cattle
P44310  78 FGGNYYGTSLPAIEENLAKGID---VFLDID-WQGAQQIRKK-VPSVKSIFILPPSLPELERRLIGRGQDSEEVIAERMS 152  Haemophilus influenz...
2ANC_F  77 VFGNYYGTSREAIEQVLATGVD---VFLDID-WQGAQQIRQK-MPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMA 151  Escherichia coli
3TVT_A 170 YNDNLYGTSVASVREVAEKGKH---CILDVS-GNAIKRLQVA-QLYPVAVFIKPKSVDSVMEMNRRMTEEQAKKTYERAI 244  fruit fly
1KJW_A 175 YNSHLYGTSVQSVREVAEQGKH---CILDVS-ANAVRRLQAA-HLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRAT 249  Norway rat
P54936 846 HEESMYGTKLETIRNIHKSGKI---AILDVE-PQALKVLRTA-EYSPFVVFIAAPNLQGMQDP-----DGSLEKLLNESD 915  Caenorhabditis elegans
P49697 355 FQGYMFGTITETIQKIHEQDKI---ALLDVE-PQTMKVLRTA-DFGPLMVFI-APTDTAAQTE-------NLQMIQKESE 421  torafugu
3NEY_B  91 YQGNMFGTKFETVHQIHKQNKI---AILDIE-PQTLKIVRTA-ELSPFIVFI-APTDQGTQTE-------ALQQLQKDSE 157  human
Q02641 296 RS--SLAEVQSEIERIFELARTlqlVALDADtINHPAQLSKT-SLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIA 372  human
O01661 266 RTSNSLAEIQTEIERIFELARSmqlVVLDCDtINHPSQLAKT-SLAPIHVYIKISSPKVLQRLIKSRGKSQSRNMNVQMV 344  Caenorhabditis elegans
4F4J_A 165 AAQAELAYA-EtgaHDKVIVNDDLDKAYKELKDFIFAE 201  Saccharomyces cerevisiae S288C
P46195 151 AARADMESSkEpglFDLIIVNDSLDKAYWALKEALSEE 188  cattle
P44310 153 KAMSEISHYdE---YDYVIVNDDFEKTLKDLQSILQSE 187  Haemophilus influenzae Rd KW20
2ANC_F 152 QAVAEMSHYaE---YDYLIVNDDFDTALTDLKTIIRAE 186  Escherichia coli
3TVT_A 245 KMEQEFGEY-----FTGVVQGDTIEEIYSKVKSMIWSQ 277  fruit fly
1KJW_A 250 KLEQEFTEC-----FSAIVEGDSFEEIYHKVKRVIEDL 282  Norway rat
P54936 916 VLRQAFGHL-----FDFIITNSDIDDTIAQLERLVEKL 948  Caenorhabditis elegans
P49697 422 TILNTYRQY-----FDVVLVNNDVNESVKIVEEALEHA 454  torafugu
3NEY_B 158 AIRSQYAHY-----FDLSLVNNGVDETLKKLQEAFDQA 190  human
Q02641 373 ASEKLAQCPpEm--FDIILDENQLEDACEHLAEYLEAY 408  human
O01661 345 AAEKLAQCQaEl--FDVLLDENQLEDACEHLADFMEAY 380  Caenorhabditis elegans
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