pfam07962: Swi3 (this model, PSSM-Id:400354 is obsolete and has been replaced by 462324)
Replication Fork Protection Component Swi3
Replication fork pausing is required to initiate a recombination events. More specifically, Swi1 is required for recombination near the mat1 locus. Swi3 has been found to co-purify with Swi1 Swi3, together with Swi1, define a fork protection complex that coordinates leading- and lagging-strand synthesis and stabilizes stalled replication forks. The Swi1-Swi3 complex is required for accurate replication, fork protection and replication checkpoint signalling.
Jiyao W et al.(2023). "The conserved domain database in 2023.",