pfam14666: RICTOR_M (this model, PSSM-Id:405369 is obsolete and has been replaced by 464248)
Rapamycin-insensitive companion of mTOR, middle domain
Rictor appears to serve as a scaffolding protein that is important for maintaining mTORC2 integrity. The mammalian target of rapamycin (mTOR) is a conserved Ser/Thr kinase that forms two functionally distinct complexes, mTROC1 and mTORC2, important for nutrient and growth-factor signalling. This region is the more conserved central section that may include several individual domains. Rictor can be inhibited in the short-term by rapamycin.
Jiyao W et al.(2023). "The conserved domain database in 2023.",