2QLY,3TON,5NN4


Conserved Protein Domain Family
NtCtMGAM_N
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pfam16863: NtCtMGAM_N (this model, PSSM-Id:407105 is obsolete and has been replaced by 465286)
N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase
NtCtMGAM_N is a beta-barrel-like structure just N-terminal to the catalytic domain of maltase-glucoamylase in eukaryotes. It contributes to the architecture of the substrate-binding site, by donating a loop that comes into close contact with two regions in the catalytic domain thereby creating the site. This family is frequently found at the N-terminus of Glycosyl hydrolase 31, pfam01055.to which it contributes as above.
Links
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Statistics
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PSSM-Id: 407105
Aligned: 330 rows
Threshold Bit Score: 65.2155
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2QLY_A          64 G-FTARLKNLPS------SPVFGS----NVDNVLLTAEYQTSNRFHFKLT--D-Q-TNNRFEVPHEHV---------Q-- 117 
3_pfamImport     1 G-WRGTLALRTGn-----RGPFGN----DAPLLELNVDRYSARQVRIRIT--D-P-AFRRYEVPNLPVqrqqdvateKed 66  
EEC15207        61 drITVQLKRRT-----------PSgidvDVPLVQVQVLFYDRNTVRIKVL--D-P-SVQRFSPPVP-------------- 111  black-legged...
XP_002412590    18 GeFSIRLRRKAT------PPLFGG----EFNDVLFSVSYETDTSLRLQVS----PaDVKLERRPLA-------------- 69   black-legged...
XP_018667949   159 G-LSQRIGKSKTa----aS-PYGE----EFDELLVTYTRVSNNKLRITIA--P-T-SVKRFEIPWTHEsas--------- 215  vase tunicate
34_pfamImport    1 G-FYQIIDKSKTa----fE-PYGT----EFDQLNVTVVRVSKFKLRIRIA--P-T-IEKRFEVPWEHEave--------- 57  
EKC41762       146 G-PTKIYDRPV------------------YKEVDVSVDEYGDNALRIFFR--P-V-NSSAFEIPDEALkinr-------- 194  Pacific oyster
EKC41761       142 G-PEEVYGMKV------------------HPEVDVTVEDYGDNALRIYFR--P-S-NTQPFEIPEEALkinr-------- 190  Pacific oyster
EFX87690       104 G-FTLDLRRRRAaddsttFSLYGG----DFDQVTFEVNYYSDSTLGLRFYpkD-A-NASELRPPVAl------------- 163  common water...
EFX87689        46 G-FSINLRRIRSadgtqsFSLYGN----DIDEITFAVNYHSDNTLGIAFY--PkGaNPEQLRPPVA-------------- 104  common water...

2QLY_A         118 -SFSGNAAAsl-tYQVEISR--Q--P-FSIKVTRRSNNR-VLFDSS--IGP---------LLFADQFLQLSTRLP 173 
3_pfamImport    67 dD-----------YQVHFTP--W--P-FGVAVTRRDSGD-VLFNSTppVESedegksfsgLVFENQFLEISTQLA 124 
EEC15207       112 -SIRDQTFSglceYGVNFSDadG-----KIRVYRFESPDiVLFQTDlsR-----------LVFTDQFLQLSTTMP 169  black-legged tick
XP_002412590    70 -QRKSRSEKtr-kYTVSYSErgE--T-FGVVVTRRDNGK-ILFDTRlpG-----------TTLAEQFLQISTRIA 127  black-legged tick
XP_018667949   216 ----ntpVQdt-lYDVQFTS--Tn-GlFGIQVTRKSTNA-ILFDTT--VGR---------MMFSDQFLQISTKLA 270  vase tunicate
34_pfamImport   58 ----dvpDYat-qYNVKYTT--NdnGiFGIIVTRKSTGS-VIFDTT--VGR---------LMFADQFLQLSTKLS 113 
EKC41762       195 ----pspATnk-kYKVEFVR--E--PtFGIKVTRKSSNT-VIFDSS--LPG---------LTFSDQFLQISTRLP 248  Pacific oyster
EKC41761       191 ----papATnk-lYRVEVVK--T--PtFGIKVIRNSTGS-VVFDSS--LPG---------LTFSDQFLQISTRLP 244  Pacific oyster
EFX87690       164 -TLTETPLTdnvhYETRIVSseNgeP-FNVQIIRKSSQA-VIFDTS--LGG---------LTIAEQFLMISTKLP 224  common water flea
EFX87689       105 -ITFPNKAIsdqrYEARLVNtgIgqP-FNFQIIRRNSNV-VIFDTS--MGG---------LTVAKQFLMLSTKLP 165  common water flea
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