1AUT,1KIG


Conserved Protein Domain Family
FXa_inhibition

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pfam14670: FXa_inhibition (this model, PSSM-Id:434114 is obsolete and has been replaced by 464251)
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Coagulation Factor Xa inhibitory site
This short domain on coagulation enzyme factor Xa is found to be the target for a potent inhibitor of coagulation, TAK-442.
Statistics
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PSSM-Id: 434114
Aligned: 127 rows
Threshold Bit Score: 25.6615
Created: 27-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1AUT_L          57 CSLDNGGC-T----HYCL-EE-VGWRRCSCAPGYK-LG-DDLLQC 92   human
EGD77618       427 CDTNNGGC-Gs--nSQCD-HTgPGTRRCTCDAGFR-STsNDGANC 466  Salpingoeca rosetta
26_pfamImport    1 CEQTPGPC-Gd--nSKCS-PTgPGTYTCLCEQGYE-SDdSAQTNC 40  
27_pfamImport    1 CMENEGIC-Gd--nATCEfAG-PGKYTCLCASGYE-HD-SPTDKC 39  
XP_004995058   247 CEDVPGRC-Ge--nSLCV-YDgPDKFHCTCVEGYE-SAnAENTDC 286  Salpingoeca rosetta
28_pfamImport    1 CSDNPNIC-Gr--nSQCS-MTgPGTYRCTCEDGYS-SStADNKNC 40  
23_pfamImport    1 CKEDNGQC-GpastTLCI-HTgPEMRNCTCHEGYT--S-TTGRNC 40  
30_pfamImport    1 CVTDNGGC-GnastTLCM-KTgPNERECSCRDGFT--S-ETGRDC 40  
EGD73983       275 CKENNGGC-GppttTRCA-VS-NGTRTCSCFEGYT--S-PTGENC 313  Salpingoeca rosetta
25_pfamImport    1 CKTNNGGCiS----ATCV-FTgPGQRTCECLPGYEkLS-PNSIEC 39  
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