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Conserved domains on  [gi|114793947|pdb|2G5F|C]
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Chain C, COG0147: Anthranilate/para-aminobenzoate synthases component I

Protein Classification

salicylate synthase( domain architecture ID 11482969)

salicylate synthase catalyzes the initial conversion of chorismate to yield the intermediate isochorismate (isochorismate synthase activity), and the subsequent elimination of the enolpyruvyl side chain to give salicylate (isochorismate pyruvate-lyase activity)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK07912 PRK07912
salicylate synthase;
2-450 0e+00

salicylate synthase;


:

Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 773.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C         2 SELSVATGAVSTASSSIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRR 81
Cdd:PRK07912   1 SELSVATGAVSTASSSIPMPAGVDPADLAAELAAVVTESVGEDYLLYERDGQWVLAAGVQAMVELDSDELRVIRDGVTRR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        82 QQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAI 161
Cdd:PRK07912  81 QQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVYRYGLQQRLAPGTPLARVFSPRTRIVVTEKGIRLFGAGIRHREAI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       162 DRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQL 241
Cdd:PRK07912 161 DRLLATGVREVPQSRSVDVSDDPSGYRDRVAVAVAEIAAGRYHKVILSRCVEVPFAVDFPATYRLGRRHNTPVRSFLLRL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       242 GGIRALGYSPELVTAVRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVI 321
Cdd:PRK07912 241 GGIRALGYSPELVTAVRADGVVITEPLAGTRAFGRGAAIDRLARDDLESNSKEIVEHAISVRSSLAEITEIAEPGSAAVI 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       322 DFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAA 401
Cdd:PRK07912 321 DFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAA 400

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
2G5F_C       402 LTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVARQ 450
Cdd:PRK07912 401 LTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLAPYLVARQ 449
 
Name Accession Description Interval E-value
PRK07912 PRK07912
salicylate synthase;
2-450 0e+00

salicylate synthase;


Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 773.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C         2 SELSVATGAVSTASSSIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRR 81
Cdd:PRK07912   1 SELSVATGAVSTASSSIPMPAGVDPADLAAELAAVVTESVGEDYLLYERDGQWVLAAGVQAMVELDSDELRVIRDGVTRR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        82 QQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAI 161
Cdd:PRK07912  81 QQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVYRYGLQQRLAPGTPLARVFSPRTRIVVTEKGIRLFGAGIRHREAI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       162 DRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQL 241
Cdd:PRK07912 161 DRLLATGVREVPQSRSVDVSDDPSGYRDRVAVAVAEIAAGRYHKVILSRCVEVPFAVDFPATYRLGRRHNTPVRSFLLRL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       242 GGIRALGYSPELVTAVRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVI 321
Cdd:PRK07912 241 GGIRALGYSPELVTAVRADGVVITEPLAGTRAFGRGAAIDRLARDDLESNSKEIVEHAISVRSSLAEITEIAEPGSAAVI 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       322 DFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAA 401
Cdd:PRK07912 321 DFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAA 400

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
2G5F_C       402 LTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVARQ 450
Cdd:PRK07912 401 LTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLAPYLVARQ 449
salicyl_syn TIGR03494
salicylate synthase; Members of this protein family are salicylate synthases, bifunctional ...
 28-448 0e+00

salicylate synthase; Members of this protein family are salicylate synthases, bifunctional enzymes that make salicylate, in two steps, from chorismate. Members are homologous to anthranilate synthase component I from Trp biosynthesis. Members typically are found in gene regions associated with siderophore or other secondary metabolite biosynthesis.


Pssm-ID: 132533 [Multi-domain]  Cd Length: 425  Bit Score: 678.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C         28 DLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAF 107
Cdd:TIGR03494   1 DLLQTLAAVLSEFAEEDYYVYERDGEWYLGIGVQAMLTIDSDGRRVTFTGVTDRQRWSGSIGDAAREAVDALLLEGDRVF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        108 GWVAFEFGVHRYGLQQRLAPHtPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATG-----VREVPQSRSVDVSD 182
Cdd:TIGR03494  81 GQVGFEFAAHARGLQFNAGEW-PLLRLFVPRTEIVVTEDNVTLFGVSAGERRRLCRLVAEGttttqIAPLPQARAVDTAT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        183 DPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGV 262
Cdd:TIGR03494 160 DPSAYRARVARAVAEIAAGRYHKVILSRAVPLPFAIDFPATLLLGRRHNTPVRSFLLRLGGIEALGFSPELVMSVRADGK 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        263 VITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRAR 342
Cdd:TIGR03494 240 VVTEPLAGTRALGGGPEHDKQLRDELLSDSKEIVEHAISVKEAIEELEQVCEPGTVVVEDFMTVRERGSVQHLGSTVSGQ 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        343 LDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGI 422
Cdd:TIGR03494 320 LAPSKDAWDAFEVLFPAITASGIPKAAALEAIMRLEKTPRGLYSGAVLLLDADGTLDAALVLRAAYQDSGRTWLQAGAGI 399

                         410       420
                  ....*....|....*....|....*.
2G5F_C        423 IEESEPEREFEETCEKLSTLTPYLVA 448
Cdd:TIGR03494 400 IAQSTPERELTETCEKLASIAPYLIA 425
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 17-423 1.35e-95

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 293.93  E-value: 1.35e-95
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       17 SIPMPAGVNPADLAAELA----AVVTESVDEDyllyECDGQW-VLAAGVQAMVELDSDELRVIRDGVTRRQqwSGRPGAA 91
Cdd:COG0147   6 YRELLALETPVSLFLKLAdgpyAFLLESAEGG----EKWGRYsFIGADPLATLTVRGGRVTIEGGGEVEPS--EGDPLDA 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       92 LGEAVDRLLLETDQ--------AFGWVAFEFGVHRYGLQQRL--APHTPLARVFSPRTRIMvsekeirlFDagirHREai 161
Cdd:COG0147  80 LRALLARFRLPPLPglppftggLVGYFGYDLVRYFERLPDLApdDLGLPDAALGLYDRLLV--------FD----HLK-- 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      162 drllatgvrevpQSRSvdvSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQL 241
Cdd:COG0147 146 ------------GTRS---NFTREEYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEGDPLALYRALRRINPSPYMFYLRF 210

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      242 GGIRALGYSPELVTAVRaDGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVI 321
Cdd:COG0147 211 GDFAIVGSSPERLVRVE-DGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVKVP 289

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      322 DFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAA 401
Cdd:COG0147 290 ELMVVERYSHVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLA 369

                       410       420
                ....*....|....*....|..
2G5F_C      402 LTLRAAYQVGGRTWLRAGAGII 423
Cdd:COG0147 370 IAIRTAVVKDGRAYVQAGAGIV 391
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 186-438 1.41e-78

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 244.39  E-value: 1.41e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        186 GFRRRVAVAVDEIAAGRYHKVILSRCVEVPFA--IDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRaDGVV 263
Cdd:pfam00425   2 DYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAgdIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVD-GGRI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        264 ITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARL 343
Cdd:pfam00425  81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        344 DPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGII 423
Cdd:pfam00425 161 KPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240

                         250
                  ....*....|....*
2G5F_C        424 EESEPEREFEETCEK 438
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
 
Name Accession Description Interval E-value
PRK07912 PRK07912
salicylate synthase;
2-450 0e+00

salicylate synthase;


Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 773.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C         2 SELSVATGAVSTASSSIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRR 81
Cdd:PRK07912   1 SELSVATGAVSTASSSIPMPAGVDPADLAAELAAVVTESVGEDYLLYERDGQWVLAAGVQAMVELDSDELRVIRDGVTRR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        82 QQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAI 161
Cdd:PRK07912  81 QQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVYRYGLQQRLAPGTPLARVFSPRTRIVVTEKGIRLFGAGIRHREAI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       162 DRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQL 241
Cdd:PRK07912 161 DRLLATGVREVPQSRSVDVSDDPSGYRDRVAVAVAEIAAGRYHKVILSRCVEVPFAVDFPATYRLGRRHNTPVRSFLLRL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       242 GGIRALGYSPELVTAVRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVI 321
Cdd:PRK07912 241 GGIRALGYSPELVTAVRADGVVITEPLAGTRAFGRGAAIDRLARDDLESNSKEIVEHAISVRSSLAEITEIAEPGSAAVI 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       322 DFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAA 401
Cdd:PRK07912 321 DFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAA 400

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*....
2G5F_C       402 LTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVARQ 450
Cdd:PRK07912 401 LTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLAPYLVARQ 449
salicyl_syn TIGR03494
salicylate synthase; Members of this protein family are salicylate synthases, bifunctional ...
 28-448 0e+00

salicylate synthase; Members of this protein family are salicylate synthases, bifunctional enzymes that make salicylate, in two steps, from chorismate. Members are homologous to anthranilate synthase component I from Trp biosynthesis. Members typically are found in gene regions associated with siderophore or other secondary metabolite biosynthesis.


Pssm-ID: 132533 [Multi-domain]  Cd Length: 425  Bit Score: 678.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C         28 DLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAF 107
Cdd:TIGR03494   1 DLLQTLAAVLSEFAEEDYYVYERDGEWYLGIGVQAMLTIDSDGRRVTFTGVTDRQRWSGSIGDAAREAVDALLLEGDRVF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        108 GWVAFEFGVHRYGLQQRLAPHtPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATG-----VREVPQSRSVDVSD 182
Cdd:TIGR03494  81 GQVGFEFAAHARGLQFNAGEW-PLLRLFVPRTEIVVTEDNVTLFGVSAGERRRLCRLVAEGttttqIAPLPQARAVDTAT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        183 DPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGV 262
Cdd:TIGR03494 160 DPSAYRARVARAVAEIAAGRYHKVILSRAVPLPFAIDFPATLLLGRRHNTPVRSFLLRLGGIEALGFSPELVMSVRADGK 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        263 VITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRAR 342
Cdd:TIGR03494 240 VVTEPLAGTRALGGGPEHDKQLRDELLSDSKEIVEHAISVKEAIEELEQVCEPGTVVVEDFMTVRERGSVQHLGSTVSGQ 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        343 LDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGI 422
Cdd:TIGR03494 320 LAPSKDAWDAFEVLFPAITASGIPKAAALEAIMRLEKTPRGLYSGAVLLLDADGTLDAALVLRAAYQDSGRTWLQAGAGI 399

                         410       420
                  ....*....|....*....|....*.
2G5F_C        423 IEESEPEREFEETCEKLSTLTPYLVA 448
Cdd:TIGR03494 400 IAQSTPERELTETCEKLASIAPYLIA 425
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 17-423 1.35e-95

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 293.93  E-value: 1.35e-95
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       17 SIPMPAGVNPADLAAELA----AVVTESVDEDyllyECDGQW-VLAAGVQAMVELDSDELRVIRDGVTRRQqwSGRPGAA 91
Cdd:COG0147   6 YRELLALETPVSLFLKLAdgpyAFLLESAEGG----EKWGRYsFIGADPLATLTVRGGRVTIEGGGEVEPS--EGDPLDA 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       92 LGEAVDRLLLETDQ--------AFGWVAFEFGVHRYGLQQRL--APHTPLARVFSPRTRIMvsekeirlFDagirHREai 161
Cdd:COG0147  80 LRALLARFRLPPLPglppftggLVGYFGYDLVRYFERLPDLApdDLGLPDAALGLYDRLLV--------FD----HLK-- 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      162 drllatgvrevpQSRSvdvSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQL 241
Cdd:COG0147 146 ------------GTRS---NFTREEYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEGDPLALYRALRRINPSPYMFYLRF 210

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      242 GGIRALGYSPELVTAVRaDGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVI 321
Cdd:COG0147 211 GDFAIVGSSPERLVRVE-DGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVKVP 289

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      322 DFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAA 401
Cdd:COG0147 290 ELMVVERYSHVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLA 369

                       410       420
                ....*....|....*....|..
2G5F_C      402 LTLRAAYQVGGRTWLRAGAGII 423
Cdd:COG0147 370 IAIRTAVVKDGRAYVQAGAGIV 391
PRK06772 PRK06772
salicylate synthase;
33-447 1.38e-78

salicylate synthase;


Pssm-ID: 102546 [Multi-domain]  Cd Length: 434  Bit Score: 250.81  E-value: 1.38e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        33 LAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRpgaALGEAVDRLL----LETDQAFG 108
Cdd:PRK06772  20 ISGVLRQFAEEECYVYERQPCWYLGKGCQARLHINADGTQATFIDDAGEQKWAVD---SIADCARRFMahpqVKGRRVYG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       109 WVAFEFGVHRYGLQQRlAPHTPLARVFSPRTRIMVSEKEIRLF-DAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGF 187
Cdd:PRK06772  97 QVGFNFAAHARGIAFN-AGEWPLLTLTVPREELIFEKGNVTVYaDSADGCRRLCEWVKEAGTTTQNAPLAVDTALNGEAY 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       188 RRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVViTEP 267
Cdd:PRK06772 176 KQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSFMFRQEGREALGFSPELVMSVTGNKVV-TEP 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       268 LAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSS 347
Cdd:PRK06772 255 LAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENK 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       348 DRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSaDGGLDAALTLRAAYQVGGRTWLRAGAGIIEESE 427
Cdd:PRK06772 335 DAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLD-DTRFDAALVLRSVFQDSQRCWIQAGAGIIAQST 413

                        410       420
                 ....*....|....*....|
2G5F_C       428 PEREFEETCEKLSTLTPYLV 447
Cdd:PRK06772 414 PERELTETREKLASIAPYLM 433
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 186-438 1.41e-78

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 244.39  E-value: 1.41e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        186 GFRRRVAVAVDEIAAGRYHKVILSRCVEVPFA--IDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRaDGVV 263
Cdd:pfam00425   2 DYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAgdIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVD-GGRI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        264 ITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARL 343
Cdd:pfam00425  81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C        344 DPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGII 423
Cdd:pfam00425 161 KPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240

                         250
                  ....*....|....*
2G5F_C        424 EESEPEREFEETCEK 438
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 176-422 1.68e-35

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 134.51  E-value: 1.68e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      176 RSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTY---RLGRRHNTPVRsFLLQLGGIRAL-GYSP 251
Cdd:COG1169  80 RSRRGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEPIDPRAllaRLRRRNPDCYT-FAVELGAGDGFvGASP 158

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      252 E-LVTavRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEpgSAAVIDFMTVRERG 330
Cdd:COG1169 159 ErLVR--RRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREALAPLCS--SLDVPEEPELLRLR 234

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C      331 SVQHLGSTIRARLDPSSDRMAALEALFP--AVtaSGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAY 408
Cdd:COG1169 235 NVQHLATPITGTLDPGVSALDLAAALHPtpAV--GGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAVAIRSAL 312

                       250
                ....*....|....
2G5F_C      409 QVGGRTWLRAGAGI 422
Cdd:COG1169 313 IDGNRARLFAGAGI 326
PRK13574 PRK13574
anthranilate synthase component I; Provisional
 179-423 2.06e-30

anthranilate synthase component I; Provisional


Pssm-ID: 184155 [Multi-domain]  Cd Length: 420  Bit Score: 121.85  E-value: 2.06e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       179 DVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVR 258
Cdd:PRK13574 152 DESLNKNNYEKIVSESLEYIRSGYIFQVVLSRFYRYLFSGDPLRIYYNLRRINPSPYMFYLKFDERYLIGSSPELLFRVQ 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       259 aDGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGST 338
Cdd:PRK13574 232 -DNIVETYPIAGTRPRGSDQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVRVPELMYVEKYSHVQHIVSK 310

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       339 IRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRA 418
Cdd:PRK13574 311 VIGTLKKKYNALDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKDLLRIQA 390


                 ....*
2G5F_C       419 GAGII 423
Cdd:PRK13574 391 GAGIV 395
PRK13571 PRK13571
anthranilate synthase component I; Provisional
 165-423 4.37e-30

anthranilate synthase component I; Provisional


Pssm-ID: 184152 [Multi-domain]  Cd Length: 506  Bit Score: 122.05  E-value: 4.37e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       165 LATGVREVPQSRSvdvSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQL--- 241
Cdd:PRK13571 213 VATFSRPVPEFRA---QRTVEEFGAAVEKLVEEIRAGEAFQVVPSQRFEMDTTADPLDVYRVLRVTNPSPYMYLLRVpns 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       242 ---GGIRALGYSPELVTAVRaDGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSA 318
Cdd:PRK13571 290 dggTDFSIVGSSPEALVTVT-DGRATTHPIAGTRWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLGRVCRPGTV 368

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       319 AVIDFMTVrERGS-VQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGG 397
Cdd:PRK13571 369 RVVDFSHI-ERYShVMHLVSTVTGELAEGRTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGD 447

                        250       260
                 ....*....|....*....|....*.
2G5F_C       398 LDAALTLRAAYQVGGRTWLRAGAGII 423
Cdd:PRK13571 448 ADTAIAIRTALMRDGTAYVQAGGGVV 473
PRK13572 PRK13572
anthranilate synthase component I; Provisional
 187-423 2.23e-27

anthranilate synthase component I; Provisional


Pssm-ID: 237432 [Multi-domain]  Cd Length: 435  Bit Score: 113.29  E-value: 2.23e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       187 FRRRVAVAVDEIAAGRYHKVILSRCVEV-----PFAIdfpltYRLGRRHNTPVRSFLLQLGGIrALGYSPELVTAVRADg 261
Cdd:PRK13572 175 FVEMVEKAKEYIYSGDVFQVVLSREYRLktdlsPFQL-----YRNLREINPSPYMFLLEFDKD-VVGASPETMASVENN- 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       262 VVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRA 341
Cdd:PRK13572 248 ILKINPIAGTAPRGKTEEEDKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYSHVQHIESEVVG 327

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       342 RLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAyQVGGRTWLRAGAG 421
Cdd:PRK13572 328 ELKEDSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMA-EIDKVCRVRAGAG 406


                 ..
2G5F_C       422 II 423
Cdd:PRK13572 407 IV 408
PRK06404 PRK06404
anthranilate synthase component I; Reviewed
 183-423 6.88e-27

anthranilate synthase component I; Reviewed


Pssm-ID: 102361 [Multi-domain]  Cd Length: 351  Bit Score: 110.73  E-value: 6.88e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       183 DPSgFRRRVAVAVDEIAAGRYHKVILSRcvEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADgV 262
Cdd:PRK06404 104 DIS-LSLKIKELIELIRAGEVLQVVISR--EFEANIDFKEKLSEFINNDRSRYVFYYRFGKYRVVGSSPENVFTVNGN-I 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       263 VITEPLAGTRAlgrgpaiDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRAR 342
Cdd:PRK06404 180 INVDPIAGTYD-------DKILSNELLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVMKIEEFSSVKHLVSQVTAK 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       343 LDPSSDRmAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSaDGGLDAALTLRAAYQVGGRTWLRAGAGI 422
Cdd:PRK06404 253 FSNASYR-DILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGIIS-KGYTDMALVIRTAYSHGNGFRVRAGAGI 330


                 .
2G5F_C       423 I 423
Cdd:PRK06404 331 V 331
PRK09070 PRK09070
aminodeoxychorismate synthase component I;
181-430 9.27e-27

aminodeoxychorismate synthase component I;


Pssm-ID: 236371 [Multi-domain]  Cd Length: 447  Bit Score: 111.72  E-value: 9.27e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       181 SDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFA--IDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVR 258
Cdd:PRK09070 179 EDPPERFTDGVERVLDYIRAGDVFQVNLSRAWQAQFAnaVDPAALYARLRAANPAPFSGLFVAAGRAIVSSSPERLVSVQ 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       259 aDGVVITEPLAGTRALGRGpAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGST 338
Cdd:PRK09070 259 -GGVVQTRPIAGTRPRFAG-DDDAALIRELVGHPKERAEHVMLIDLERNDLGRICAPGSVEVDELMTVESYAHVHHIVSN 336

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       339 IRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRA 418
Cdd:PRK09070 337 VRGRLRDGVTPGEVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGNQVRFRT 416

                        250
                 ....*....|..
2G5F_C       419 GAGIIEESEPER 430
Cdd:PRK09070 417 GAGIVVDSDPER 428
PLN02445 PLN02445
anthranilate synthase component I
 151-423 2.65e-23

anthranilate synthase component I


Pssm-ID: 215244 [Multi-domain]  Cd Length: 523  Bit Score: 102.45  E-value: 2.65e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       151 FDAGIRHREA-IDRLLATGVREVPQSrSVDVSDDPSG------------FRRRVAVAVDEIAAGRYHKVILSRCVEV--- 214
Cdd:PLN02445 190 YEDGMKRLEAlVSRLQDINPPKLSPG-SVKLSTNQFGpsleksnmtseeYKNAVLQAKEHILAGDIFQIVLSQRFERrtf 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       215 --PFAIdfpltYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRAdGVVITEPLAGTRALGRGPAIDRLARDDLESNS 292
Cdd:PLN02445 269 adPFEV-----YRALRIVNPSPYMIYLQARGCILVASSPEILTRVKK-NKIVNRPLAGTRRRGKTPEEDKALEKDLLADE 342

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       293 KEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVrERGS-VQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGV 371
Cdd:PLN02445 343 KQCAEHIMLVDLGRNDVGKVSKAGSVKVEKLMNI-ERYShVMHISSTVTGELLDHLTSWDALRAALPVGTVSGAPKVRAM 421

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       372 EAIFRLDECPRGLYSGAVVMLSADGGLDAALTLR-------AAYQV--------GGRTW---LRAGAGII 423
Cdd:PLN02445 422 ELIDELEVTRRGPYSGGFGGVSFTGDMDIALALRtmvfptaARYDTmysykdtnSRREWvahLQAGAGIV 491
PRK07054 PRK07054
isochorismate synthase;
191-449 1.60e-22

isochorismate synthase;


Pssm-ID: 235920 [Multi-domain]  Cd Length: 475  Bit Score: 99.84  E-value: 1.60e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       191 VAVAVDEIAAGRYHKVILSRCVEVPFAIDF---PLTYRLGRRHnTPVRSFLLQLGGIRALGYSPELVTAVRAdGVVITEP 267
Cdd:PRK07054 201 VRRAVDAIRGGAFGKVVLARDVLQQYARPVaigPLLRRLRLRD-PHAHLFAFRRGNACFLGATPERLVRVAA-GDLHTHA 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       268 LAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVrsslEEITDIAEPGSAA--VIDFMTVRERGSVQHLGSTIRARLDP 345
Cdd:PRK07054 279 LAGTIARGADPAEDARLGAALMASAKDRLEHALVV----DAIRAALAPLSRAldIPDQPSLHRLPRLQHLSTPIRATLAP 354

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       346 SSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEE 425
Cdd:PRK07054 355 DATLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVAD 434

                        250       260
                 ....*....|....*....|....
2G5F_C       426 SEPEREFEETCEKLSTLTPYLVAR 449
Cdd:PRK07054 435 SEPASEYRETCLKLSGMREALRAR 458
PRK05940 PRK05940
anthranilate synthase component I;
250-423 1.04e-20

anthranilate synthase component I;


Pssm-ID: 235651 [Multi-domain]  Cd Length: 463  Bit Score: 94.03  E-value: 1.04e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       250 SPELVTAVRADgVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVrER 329
Cdd:PRK05940 255 SPERLVQLQGN-QAQTRPIAGTRPRGKTPAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQWGSVEVDELLTI-ER 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       330 GS-VQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRA-- 406
Cdd:PRK05940 333 YShVIHLVSNVVGTLQPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLDLNILIRTll 412

                        170       180
                 ....*....|....*....|
2G5F_C       407 ---AYQVGGRTWLRAGAGII 423
Cdd:PRK05940 413 ytpLSRGLSTIWGQVGAGIV 432
PRK13567 PRK13567
anthranilate synthase component I; Provisional
 221-405 1.11e-19

anthranilate synthase component I; Provisional


Pssm-ID: 184148 [Multi-domain]  Cd Length: 468  Bit Score: 90.97  E-value: 1.11e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       221 PLTYRLGR---RHNTPVRSFLLQLGGIRALGYSPELVTAVRaDGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVE 297
Cdd:PRK13567 240 QLSFQLYQnlkRQNPSPYMYYLNIDQPYIVGSSPESFVSVK-DQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSE 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       298 HAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRL 377
Cdd:PRK13567 319 HRMLVDLGRNDIHRVSKIGTSKITKLMVIEKYEHVMHIVSEVTGKINQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQ 398

                        170       180
                 ....*....|....*....|....*...
2G5F_C       378 DECPRGLYSGAVVMLSADGGLDAALTLR 405
Cdd:PRK13567 399 YPHKRGVYSGGVGYINCNHNLDFALAIR 426
PRK07508 PRK07508
aminodeoxychorismate synthase component I;
187-412 5.38e-19

aminodeoxychorismate synthase component I;


Pssm-ID: 236035 [Multi-domain]  Cd Length: 378  Bit Score: 88.14  E-value: 5.38e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       187 FRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYR-LGRRHntPVR-SFLLQLGGIRALGYSPELVTAVRADGVVI 264
Cdd:PRK07508 114 YAQRFERLHRHIRAGDCYQANLTFPLDARWGGDPLALFWaLAARQ--PVGyGALVDLGGPVILSRSPELFFRVDGEGWIE 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       265 TEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLD 344
Cdd:PRK07508 192 THPMKGTAPRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDISRISEVGSLDVPELFDIETYPTVHQMVSRVRARLL 271

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
2G5F_C       345 PSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLD---AALTL------RAAYQVGG 412
Cdd:PRK07508 272 PGLGLADIFAALFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWIAPDGRMRfnvAIRTLslfpggRAVFNVGG 348
pabB PRK15465
aminodeoxychorismate synthase component 1;
211-423 3.84e-17

aminodeoxychorismate synthase component 1;


Pssm-ID: 185362 [Multi-domain]  Cd Length: 453  Bit Score: 83.43  E-value: 3.84e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       211 CVEVPFAIDFPLTY---------RLGRRHNTPVRSFL-LQLGGIRALgySPELVTAVRaDGVVITEPLAGTRALGRGPAI 280
Cdd:PRK15465 209 CYQVNLAQRFHATYsgdewqaflQLNQANRAPFSAFLrLEQGAILSL--SPERFILCD-NSEIQTRPIKGTLPRLPDPQE 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       281 DRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIRARLDPSSDRMAALEALFPAV 360
Cdd:PRK15465 286 DSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITARLPEQLHASDLLRAAFPGG 365

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
2G5F_C       361 TASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGII 423
Cdd:PRK15465 366 SITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIV 428
PRK05877 PRK05877
aminodeoxychorismate synthase component I; Provisional
 183-422 5.85e-17

aminodeoxychorismate synthase component I; Provisional


Pssm-ID: 235634 [Multi-domain]  Cd Length: 405  Bit Score: 82.44  E-value: 5.85e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       183 DPSGFRRRVAVAVDEIAAGRyhkvILSRCVEVPFAIDF---PLTYRL-GRRHNTPVRSFLLQ--LGGIRALgySPELVTA 256
Cdd:PRK05877 140 DRAAHRDGVLACLEAIAAGE----VYQACVCTQFTGTVtgsPLDFFAdGVARTAPARAAYLAgdWGAVASL--SPELFLR 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       257 vRADGVVITEPLAGTRALGRGPAidrlardDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLG 336
Cdd:PRK05877 214 -RRGSVVTSSPIKGTLPLDADPS-------ALRASAKDVAENIMIVDLVRNDLGRVARTGTVTVPELLVVRPAPGVWHLV 285

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       337 STIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAA-YQVGGRTW 415
Cdd:PRK05877 286 STVSAQVPDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGCELNVAIRTVeFDADGNAV 365


                 ....*..
2G5F_C       416 LRAGAGI 422
Cdd:PRK05877 366 LGVGGGI 372
PRK06923 PRK06923
isochorismate synthase DhbC; Validated
 183-423 5.88e-17

isochorismate synthase DhbC; Validated


Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 82.47  E-value: 5.88e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       183 DPSGFRRRVAVAVDEIAAGRYHKVILSRCVEV--PFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRA------LGYSPELV 254
Cdd:PRK06923 120 DPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVksSEKIDKQKLLRELAEHNKHGYTFAVNLPKDENensktlIGASPELL 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       255 TAvRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAIsvrssleeitdIAEPGSAAVIDF---MTVRERGS 331
Cdd:PRK06923 200 VS-RHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAV-----------VVEAVAAALRPYchtLHVPEKPS 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       332 V------QHLGSTIRARL-DPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTL 404
Cdd:PRK06923 268 VihteamWHLSTEVKGELkDPNTSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTI 347

                        250
                 ....*....|....*....
2G5F_C       405 RAAYQVGGRTWLRAGAGII 423
Cdd:PRK06923 348 RCAEVEENTLRLYAGAGVV 366
PLN02889 PLN02889
oxo-acid-lyase/anthranilate synthase
 250-423 7.86e-14

oxo-acid-lyase/anthranilate synthase


Pssm-ID: 215481 [Multi-domain]  Cd Length: 918  Bit Score: 73.73  E-value: 7.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       250 SPELVTAVRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRER 329
Cdd:PLN02889 712 SPERFLKLDRNGMLEAKPIKGTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLGRVCEPGSVHVPNLMDVESY 791

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       330 GSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQ 409
Cdd:PLN02889 792 TTVHTMVSTIRGKKRSNMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFFSYNQTFDLNIVIRTVVI 871

                        170
                 ....*....|....
2G5F_C       410 VGGRTWLRAGAGII 423
Cdd:PLN02889 872 HEGEASIGAGGAIV 885
PLN02786 PLN02786
isochorismate synthase
 204-423 9.50e-13

isochorismate synthase


Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 69.81  E-value: 9.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       204 HKVILSRCVEVPFAIDF-PLTY--RLgRRHNTPVRSFLLQLGGIRA-LGYSPELVTAVRADGVViTEPLAGTRALGRGPA 279
Cdd:PLN02786 281 KKVVLARSSRIITDTDIdPIAWlaCL-QVEGQNAYQFCLQPPDAPAfIGNTPEQLFHRKGLGVC-SEALAATRPRGGSSA 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       280 IDRLARDDLESNSKEIVEHAI---SVRSSLEEITD--IAEPGSAavidfmtVRERGSVQHLGSTIRARLDPSSDRMAALE 354
Cdd:PLN02786 359 RDLQIELDLLTSPKDDLEFSIvreNIREKLEAICDrvVVEPHKA-------IRKLARVQHLYAQLAGRLRSEDDEFDILA 431

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       355 ALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSAdGGLDAALTLRAA-YQVGGRTWLRAGAGII 423
Cdd:PLN02786 432 ALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFGG-GESEFAVGIRSAlVEKGLGALIYAGTGIV 500
PRK13564 PRK13564
anthranilate synthase component 1;
267-423 9.80e-12

anthranilate synthase component 1;


Pssm-ID: 237428 [Multi-domain]  Cd Length: 520  Bit Score: 66.78  E-value: 9.80e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       267 PLAGTRALGRGP--AIDR-L-ARDDLE--SNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVrERGS-VQHLGSTI 339
Cdd:PRK13564 325 PIAGTRPRGRRAdgSIDRdLdSRIELElrTDHKELAEHLMLVDLARNDLARICQPGSRYVADLLKV-DRYShVMHLVSRV 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       340 RARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAG 419
Cdd:PRK13564 404 VGELRHDLDALHAYRACMNMGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTCIVIRSAFVENGIATVQAG 483


                 ....
2G5F_C       420 AGII 423
Cdd:PRK13564 484 AGVV 487
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 187-442 4.02e-10

isochorismate synthase EntC; Provisional


Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 61.43  E-value: 4.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       187 FRRRVAVAVDEIAAGRYHKVILSRCVEVPF--AID-FPLTYRLGRRHntPVrSF----LLQLGGIrALGYSPELVtaVRA 259
Cdd:PRK15016 129 FEAMVARAAALTATPQVDKVVLSRLIDITTdaAIDsGALLERLIAQN--PV-SYnfhvPLADGGV-LLGASPELL--LRK 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       260 DGVVITE-PLAGTRALGRGPAIDRLARDDLESNSKEIVEHAIsVRSSLEEI-----TDIAEPGSAAVIDFMTVrergsvQ 333
Cdd:PRK15016 203 DGERFSSlPLAGSARRQPDEVLDREAGNRLLASEKDRHEHEL-VTQAMKEVlrersSELHVPSSPQLITTPTL------W 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       334 HLGSTI--RARLDPSSDRMAALeaLFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVG 411
Cdd:PRK15016 276 HLATPFegKANAQENALTLACL--LHPTPALSGFPHQAAKQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRE 353

                        250       260       270
                 ....*....|....*....|....*....|.
2G5F_C       412 GRTWLRAGAGIIEESEPEREFEETCEKLSTL 442
Cdd:PRK15016 354 NQVRLFAGAGIVPASSPLGEWRETGVKLSTM 384
PRK13566 PRK13566
anthranilate synthase component I;
191-420 2.93e-09

anthranilate synthase component I;


Pssm-ID: 237429 [Multi-domain]  Cd Length: 720  Bit Score: 59.16  E-value: 2.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       191 VAVAVDEIAAGRYHKVILS-----RCVEVPFAIdfpltYRLGRRHNTPVRSFLLQLGGIRAL-GYSPELVtaVRADGV-V 263
Cdd:PRK13566 250 VEKAKESFRRGDLFEVVPGqtfyePCERSPSEI-----FRRLKEINPSPYGFFINLGDGEYLvGASPEMF--VRVEGRrV 322

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       264 ITEPLAGTRALGRGPAIDRLARDDLESNSKEivehaisvRSSLEEITD--------IAEPGSAAVIDF----MTVRERGS 331
Cdd:PRK13566 323 ETCPISGTIKRGADAIGDAEQIRKLLNSKKD--------ESELTMCTDvdrndksrVCEPGSVKVIGRrqieMYSRLIHT 394

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       332 VQHlgstIRARLDPSSDrmaALEALFP---AVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAY 408
Cdd:PRK13566 395 VDH----VEGRLRPGFD---ALDAFLThawAVTVTGAPKLWAMQFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLRTIR 467

                        250
                 ....*....|..
2G5F_C       409 QVGGRTWLRAGA 420
Cdd:PRK13566 468 IKDGVAEVRVGA 479
PRK15012 PRK15012
menaquinone-specific isochorismate synthase; Provisional
 147-424 6.24e-09

menaquinone-specific isochorismate synthase; Provisional


Pssm-ID: 184974 [Multi-domain]  Cd Length: 431  Bit Score: 57.93  E-value: 6.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       147 EIRLFDAGIRHREAIDRLlaTGVREVPQSRSVDVSD----DPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFA--IDF 220
Cdd:PRK15012 130 ESSLQHDAIQAKEFLATL--VSIKPLPGLHLTTTREqhwpDKTGWTQLIELATKTIAEGELDKVVLARATDLHFAspVNA 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       221 PLTYRLGRRHNTPVRSFLLQLGGIRA-LGYSPELVTAvRADGVVITEPLAGTRALGRGPAIDRLARDDLESNSKEIVEHA 299
Cdd:PRK15012 208 AAMMAASRRLNLNCYHFYMAFDAENAfLGSSPERLWR-RRDKALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENM 286

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       300 ISVRSSLEEITdiAEPGSAAVIDFMTVRERgSVQHLGSTIRARLDPSSDRMAaLEALFPAVTASGIPKAAGVEAIFRLDE 379
Cdd:PRK15012 287 LVVEDICQRLQ--ADTQTLDVLPPQVLRLR-KVQHLRRCIWTSLNKADDVIC-LHQLQPTAAVAGLPRDLARQFIARHEP 362

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
2G5F_C       380 CPRGLYSGAVVMLSADGGlDAALTLRAAYQVGGRTWLRAGAGIIE 424
Cdd:PRK15012 363 FTREWYAGSAGYLSLQQS-EFCVSLRSAKVSGNVVRLYAGAGIVR 406
PRK07093 PRK07093
para-aminobenzoate synthase component I; Validated
 249-422 3.11e-04

para-aminobenzoate synthase component I; Validated


Pssm-ID: 235932 [Multi-domain]  Cd Length: 323  Bit Score: 42.55  E-value: 3.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       249 YSPElvTAVR-ADGVVITEPLAGTralgrgpaIDRL---ARDDLESNSKEIVEHAISV---RSSL----EEITdiaepgs 317
Cdd:PRK07093 131 FSPE--PFVRiEDNKISTYPMKGT--------IDASlpnAEEKLLNDEKEFAEHATIVdllRNDLsmvaKNVR------- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2G5F_C       318 aaVIDFMTVRE----RGSVQHLGSTIRARLDPS-SDRMAA-LEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGavVM 391
Cdd:PRK07093 194 --VTRFRYIDKiktnKGEILQTSSEISGTLPENwQENIGDiLAKLLPAGSITGAPKEKTVEIIEQAEGYERGFYTG--VF 269

                        170       180       190
                 ....*....|....*....|....*....|..
2G5F_C       392 LSADGG-LDAALTLRAAYQVGGRTWLRAGAGI 422
Cdd:PRK07093 270 GYFDGEsLDSAVMIRFIEQENDGLYFKSGGGI 301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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