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Conserved domains on  [gi|228311932|pdb|3CXC|U]
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Chain U, RIBOSOMAL PROTEIN L29

Protein Classification

50S ribosomal protein L29( domain architecture ID 10794031)

50S ribosomal protein L29 binds 23S rRNA and is not essential for growth; it is one of the proteins that surrounds the polypeptide exit tunnel on the outside of the 50s ribosomal subunit

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14549 PRK14549
50S ribosomal protein L29P; Provisional
 1-68 2.78e-26

50S ribosomal protein L29P; Provisional


:

Pssm-ID: 237751  Cd Length: 69  Bit Score: 90.82  E-value: 2.78e-26
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3CXC_U        1 TVLHVQEIRDMTPAEREAELDDLKTELLNARAVQAAGGAPENPGRIKELRKAIARIKTIQGEEGDLQE 68
Cdd:PRK14549  2 AILRASEIREMSPEEREEKLEELKLELLKERAQAAMGGAPENPGRIREIRRTIARILTIQREKKREAK 69
 
Name Accession Description Interval E-value
PRK14549 PRK14549
50S ribosomal protein L29P; Provisional
 1-68 2.78e-26

50S ribosomal protein L29P; Provisional


Pssm-ID: 237751  Cd Length: 69  Bit Score: 90.82  E-value: 2.78e-26
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3CXC_U        1 TVLHVQEIRDMTPAEREAELDDLKTELLNARAVQAAGGAPENPGRIKELRKAIARIKTIQGEEGDLQE 68
Cdd:PRK14549  2 AILRASEIREMSPEEREEKLEELKLELLKERAQAAMGGAPENPGRIREIRRTIARILTIQREKKREAK 69
RpmC COG0255
Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 ...
 5-62 2.02e-17

Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440025 [Multi-domain]  Cd Length: 65  Bit Score: 68.22  E-value: 2.02e-17
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*...
3CXC_U       5 VQEIRDMTPAEREAELDDLKTELLNARAvQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:COG0255  3 AKELRELSDEELKEKLKELKKELFNLRF-QHATGQLENPHRIREVRRDIARIKTVLRE 59
Ribosomal_L29 pfam00831
Ribosomal L29 protein;
6-62 2.31e-17

Ribosomal L29 protein;


Pssm-ID: 459954  Cd Length: 56  Bit Score: 67.80  E-value: 2.31e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
3CXC_U         6 QEIRDMTPAEREAELDDLKTELLNARaVQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:pfam00831  1 KELRELSDEELEEKLKELKKELFNLR-FQKATGQLENPSRIREVRRDIARIKTVLRE 56
Ribosomal_L29_HIP cd00427
Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called ...
 6-62 3.05e-16

Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it participates in forming a protein ring that surrounds the polypeptide exit channel, providing structural support for the ribosome. L29 is involved in forming the translocon binding site, along with L19, L22, L23, L24, and L31e. In addition, L29 and L23 form the interaction site for trigger factor (TF) on the ribosomal surface, adjacent to the exit tunnel. L29 forms numerous interactions with L23 and with the 23S rRNA. In some eukaryotes, L29 is referred to as L35, which is distinct from L35 found in bacteria and some eukaryotes (primarily plastids and mitochondria). The mammalian homolog, HIP, is found on the surface of many tissues and cell lines. It is believed to play a role in cell adhesion and modulation of blood coagulation. It has also been shown to inhibit apoptosis in cancer cells.


Pssm-ID: 238243  Cd Length: 57  Bit Score: 65.20  E-value: 3.05e-16
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*..
3CXC_U       6 QEIRDMTPAEREAELDDLKTELLNARaVQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:cd00427  1 KELREKSDEELQEKLDELKKELFNLR-FQKATGQLENPHRIRKVRKDIARIKTVLNE 56
L29 TIGR00012
ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in ...
 7-62 7.24e-13

ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in prokaryotic (50S) large subunits and L35 in eukaryotic (60S) large subunits. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 272854  Cd Length: 55  Bit Score: 56.47  E-value: 7.24e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
3CXC_U         7 EIRDMTPAEREAELDDLKTELLNARaVQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:TIGR00012  1 ELREKSKEELAKKLDELKKELFELR-FQKATGQLEKPHRIRQVRRDIARLLTVLRE 55
 
Name Accession Description Interval E-value
PRK14549 PRK14549
50S ribosomal protein L29P; Provisional
 1-68 2.78e-26

50S ribosomal protein L29P; Provisional


Pssm-ID: 237751  Cd Length: 69  Bit Score: 90.82  E-value: 2.78e-26
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3CXC_U        1 TVLHVQEIRDMTPAEREAELDDLKTELLNARAVQAAGGAPENPGRIKELRKAIARIKTIQGEEGDLQE 68
Cdd:PRK14549  2 AILRASEIREMSPEEREEKLEELKLELLKERAQAAMGGAPENPGRIREIRRTIARILTIQREKKREAK 69
RpmC COG0255
Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 ...
 5-62 2.02e-17

Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440025 [Multi-domain]  Cd Length: 65  Bit Score: 68.22  E-value: 2.02e-17
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*...
3CXC_U       5 VQEIRDMTPAEREAELDDLKTELLNARAvQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:COG0255  3 AKELRELSDEELKEKLKELKKELFNLRF-QHATGQLENPHRIREVRRDIARIKTVLRE 59
Ribosomal_L29 pfam00831
Ribosomal L29 protein;
6-62 2.31e-17

Ribosomal L29 protein;


Pssm-ID: 459954  Cd Length: 56  Bit Score: 67.80  E-value: 2.31e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
3CXC_U         6 QEIRDMTPAEREAELDDLKTELLNARaVQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:pfam00831  1 KELRELSDEELEEKLKELKKELFNLR-FQKATGQLENPSRIREVRRDIARIKTVLRE 56
Ribosomal_L29_HIP cd00427
Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called ...
 6-62 3.05e-16

Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it participates in forming a protein ring that surrounds the polypeptide exit channel, providing structural support for the ribosome. L29 is involved in forming the translocon binding site, along with L19, L22, L23, L24, and L31e. In addition, L29 and L23 form the interaction site for trigger factor (TF) on the ribosomal surface, adjacent to the exit tunnel. L29 forms numerous interactions with L23 and with the 23S rRNA. In some eukaryotes, L29 is referred to as L35, which is distinct from L35 found in bacteria and some eukaryotes (primarily plastids and mitochondria). The mammalian homolog, HIP, is found on the surface of many tissues and cell lines. It is believed to play a role in cell adhesion and modulation of blood coagulation. It has also been shown to inhibit apoptosis in cancer cells.


Pssm-ID: 238243  Cd Length: 57  Bit Score: 65.20  E-value: 3.05e-16
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*..
3CXC_U       6 QEIRDMTPAEREAELDDLKTELLNARaVQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:cd00427  1 KELREKSDEELQEKLDELKKELFNLR-FQKATGQLENPHRIRKVRKDIARIKTVLNE 56
L29 TIGR00012
ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in ...
 7-62 7.24e-13

ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in prokaryotic (50S) large subunits and L35 in eukaryotic (60S) large subunits. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 272854  Cd Length: 55  Bit Score: 56.47  E-value: 7.24e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
3CXC_U         7 EIRDMTPAEREAELDDLKTELLNARaVQAAGGAPENPGRIKELRKAIARIKTIQGE 62
Cdd:TIGR00012  1 ELREKSKEELAKKLDELKKELFELR-FQKATGQLEKPHRIRQVRRDIARLLTVLRE 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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