|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
134-673 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 666.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 134 PTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIpDVSIKPGLEG---FALPRTCAAPQqgqmqrcpi 210
Cdd:smart00350 2 PSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATL-GPEIQSGRETeptVCPPRECQSPT--------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 211 dPYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVGVYSI----KKLIQKKGGDKSLQ 286
Cdd:smart00350 72 -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNvpygFKLNTVKGLPVFAT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 287 GIRTPYLRVLGIHMETSGPGrTNFTTFTPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPD 366
Cdd:smart00350 151 YIEANHVRKLDYKRSFEDSS-FSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPD 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 367 GITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEF 446
Cdd:smart00350 230 GMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEF 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 447 DKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDV 525
Cdd:smart00350 310 DKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVDE 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 526 LKDATLAKHVIEVHVNaSAAKERDIAGVPktattdsdgvmtmfdtdgfLTIEFLKKFVTYARLNCGPRLTPQASEKLVNH 605
Cdd:smart00350 390 ERDRELAKHVVDLHRY-SHPEEDEAFEPP-------------------LSQEKLRKYIAYAREKIKPKLSEEAADKLVKA 449
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
8OUW_5 606 YVKMRNPVVNADAFKSgkkahnsaIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTI 673
Cdd:smart00350 450 YVDLRKEDSQTESRSS--------IPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
333-671 |
0e+00 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 618.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 333 LIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAG 412
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 413 LTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYG 492
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 493 RWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDiagvpktattdsdgvmtmfDTD 571
Cdd:cd17756 161 RYDDLKTpGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQ-------------------ENE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 572 GFLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNPVVNADAfksgKKAHNSAIPITVRQLEAIVRIAESIAKME 651
Cdd:cd17756 222 GEIPISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRKDVRQNEL----ESDNRSSIPITVRQLEAIIRISESLAKME 297
|
330 340
....*....|....*....|
8OUW_5 652 LQQFATDKHVEEALRLFRVS 671
Cdd:cd17756 298 LSPIATEKHVEEAIRLFQVS 317
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
35-671 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 591.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 35 LITQFRNFIRDFstggfgmIYRDQLKR--NYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAK-IVADEIt 111
Cdd:COG1241 5 LVDKFEEFLRRY-------KYRDEILElaQEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALReIDLEPY- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 112 tprpkgEEKLHDIQVTLTldEYP--TSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIPdvsIKPGLE 189
Cdd:COG1241 77 ------DVSLGDAHVRIT--NLPetVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETY---VPQTGE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 190 GFALPRTCAA-PQQGqmqrcpidPYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVG 268
Cdd:COG1241 146 KLQEPHECPGcGRQG--------PFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTG 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 269 vysIKKLIQKKGGDKSLqGIRTPYLRVLGIHMETsgpgrTNFTTF--TPEEERMFKTLAQRKDAYELIAKSIAPSIYGSA 346
Cdd:COG1241 218 ---ILRIEQRTSGRGKS-TIFDLYLEANSIEVEE-----KEFEEIeiTEEDEEKIKELSKDPDIYEKIIASIAPSIYGYE 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 347 DIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRD-PQSRS 425
Cdd:COG1241 289 EIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 426 FIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNID 504
Cdd:COG1241 369 WTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPiAEQID 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 505 FMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHvnaSAAKERDIAGVPKTATTDSDgvmtmfdtdgfLTIEFLKKFVT 584
Cdd:COG1241 449 LPPTLLSRFDLIFVLRDKPDEERDRELARHILKVH---RAGELLEQEIEEETEEVKPE-----------IDPDLLRKYIA 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 585 YARLNCGPRLTPQASEKLVNHYVKMRNpvvnadafKSGKKahNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEA 664
Cdd:COG1241 515 YARRNVFPVLTEEAKDLIEDFYVDMRK--------KGEDE--DSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERA 584
|
....*..
8OUW_5 665 LRLFRVS 671
Cdd:COG1241 585 IRLVDSC 591
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
35-746 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 561.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 35 LITQFRNFIRDFSTGGFGMIYRDQLKRNYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAKIVADEITTPR 114
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 115 PKGEEKLHdiqVTLTLDEYPTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTI--PDVSIKPG--LEG 190
Cdd:NF040949 81 AEEVAKFH---VRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFewPEEEEESYeiVEP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 191 FALPRTCAAPQQgqmqrcpidpYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVGvy 270
Cdd:NF040949 158 PTVCPVCGKPGS----------FRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTG-- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 271 sIKKLIQKKGGDKSLQGIRTPYLRVlgIHMETSgpgRTNF--TTFTPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADI 348
Cdd:NF040949 226 -ILRIKPDSSLKKGSRPIFKNYIEA--NHIEVS---QKELeeVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEI 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 349 KKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSFIM 428
Cdd:NF040949 300 KEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 429 EGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNIDFMP 507
Cdd:NF040949 380 EAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSvAENIDLPP 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 508 TILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKErdiagvpktattdsdgvmtmfdtdgFLTIEFLKKFVTYAR 587
Cdd:NF040949 460 TILSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEKVKP-------------------------EIDPDLLKKYIAYAR 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 588 LNCGPRLTPQASEKLVNHYVKMRNPVVNADafksgkkAHNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRL 667
Cdd:NF040949 515 KYVRPKLTEEAKKLIEDFYVEMRKSSKSSE-------DPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRL 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 668 FRvSTIEAAA----TGNL--AGVEGFTSTADQEALNRIEVQMKKRFAIGTHVSEHLIVQDfvARQH-YRESLVKKVIDNL 740
Cdd:NF040949 588 ML-AFLESVGidveTGKIdiDTIMTGKPKSKREKMSKIVEIIKELEEEEECVKIKELIKE--AEKKgIDEEKVEELISDL 664
|
....*.
8OUW_5 741 VRRGDL 746
Cdd:NF040949 665 KRSGEI 670
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
317-539 |
5.43e-138 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 405.76 E-value: 5.43e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 317 EERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQV 396
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 397 SPIGVYTSGKGSSAAGLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTT 476
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8OUW_5 477 LNSRCSVLAAANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVH 539
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSiAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
41-675 |
4.84e-84 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 286.12 E-value: 4.84e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 41 NFI----RDFSTGgfgmiyrdqlkrnyFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAKIVADEITTPR-- 114
Cdd:PTZ00111 129 NFIkenlRDHSTG--------------YSRILPFEVDLMHVYSFDKVLYKLLVTFPADCIAELDKVLVKLFNELLSKHys 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 115 -PKGEEKLHDIQVTLTLDEYPTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKhtipdvsiKPGLEGFAl 193
Cdd:PTZ00111 195 dLSLENNSFFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQK--------KIGLNDYQ- 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 194 PRTCAAPQ---QGQMQRcPI--------DPYIMLPDKCECVDYQTLKLQENPEDVPHGEMP------RHLQLFTERY--- 253
Cdd:PTZ00111 266 PCTCEHYEyviQGEVNE-PLlcnecnskYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvDNSGLNGEIYmkd 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 254 -----------LTDKVVPGNRVTIVGVYSIKKlIQKKGGDKSLQGIRTPYLRVLGIHMETSGPGRT---------NFTTF 313
Cdd:PTZ00111 345 nevinlnlyddLIDSVKTGDRVTVVGILKVTP-IRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQpekglkylgNENDF 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 314 TPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGAR-----KKLPDGITR----RGDINVLLLGDPGT 384
Cdd:PTZ00111 424 SDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGT 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 385 AKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASV-IRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQ 463
Cdd:PTZ00111 504 AKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQ 583
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 464 QTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKD----ATLAKHVIEV 538
Cdd:PTZ00111 584 QTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAvIENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLP 663
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 539 HV----NASAAKERDIAGVPKTATTDSDGVMTMFDTDgfltieFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRN--- 611
Cdd:PTZ00111 664 HMtgsgNDEDTYDRSNTMHVEDESLRSEKDYNKNDLD------MLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQgnf 737
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
8OUW_5 612 PVVNADAFKSGK----------KAHNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTIEA 675
Cdd:PTZ00111 738 QTSNLDELEHAQedddddlyyqSSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQS 811
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
38-129 |
4.35e-18 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 79.64 E-value: 4.35e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 38 QFRNFIRDF-STGGFGMIYRDQLKRNYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAKIVADEItTPRPK 116
Cdd:pfam14551 3 KFKDFLEEFrEDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKEL-SEDPD 81
|
90
....*....|...
8OUW_5 117 GEEKLHDIQVTLT 129
Cdd:pfam14551 82 YAEEEKEFQVRFY 94
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
134-673 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 666.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 134 PTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIpDVSIKPGLEG---FALPRTCAAPQqgqmqrcpi 210
Cdd:smart00350 2 PSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATL-GPEIQSGRETeptVCPPRECQSPT--------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 211 dPYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVGVYSI----KKLIQKKGGDKSLQ 286
Cdd:smart00350 72 -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNvpygFKLNTVKGLPVFAT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 287 GIRTPYLRVLGIHMETSGPGrTNFTTFTPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPD 366
Cdd:smart00350 151 YIEANHVRKLDYKRSFEDSS-FSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPD 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 367 GITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEF 446
Cdd:smart00350 230 GMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEF 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 447 DKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDV 525
Cdd:smart00350 310 DKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVDE 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 526 LKDATLAKHVIEVHVNaSAAKERDIAGVPktattdsdgvmtmfdtdgfLTIEFLKKFVTYARLNCGPRLTPQASEKLVNH 605
Cdd:smart00350 390 ERDRELAKHVVDLHRY-SHPEEDEAFEPP-------------------LSQEKLRKYIAYAREKIKPKLSEEAADKLVKA 449
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
8OUW_5 606 YVKMRNPVVNADAFKSgkkahnsaIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTI 673
Cdd:smart00350 450 YVDLRKEDSQTESRSS--------IPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
333-671 |
0e+00 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 618.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 333 LIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAG 412
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 413 LTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYG 492
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 493 RWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDiagvpktattdsdgvmtmfDTD 571
Cdd:cd17756 161 RYDDLKTpGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQ-------------------ENE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 572 GFLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNPVVNADAfksgKKAHNSAIPITVRQLEAIVRIAESIAKME 651
Cdd:cd17756 222 GEIPISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRKDVRQNEL----ESDNRSSIPITVRQLEAIIRISESLAKME 297
|
330 340
....*....|....*....|
8OUW_5 652 LQQFATDKHVEEALRLFRVS 671
Cdd:cd17756 298 LSPIATEKHVEEAIRLFQVS 317
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
35-671 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 591.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 35 LITQFRNFIRDFstggfgmIYRDQLKR--NYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAK-IVADEIt 111
Cdd:COG1241 5 LVDKFEEFLRRY-------KYRDEILElaQEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALReIDLEPY- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 112 tprpkgEEKLHDIQVTLTldEYP--TSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIPdvsIKPGLE 189
Cdd:COG1241 77 ------DVSLGDAHVRIT--NLPetVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETY---VPQTGE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 190 GFALPRTCAA-PQQGqmqrcpidPYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVG 268
Cdd:COG1241 146 KLQEPHECPGcGRQG--------PFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTG 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 269 vysIKKLIQKKGGDKSLqGIRTPYLRVLGIHMETsgpgrTNFTTF--TPEEERMFKTLAQRKDAYELIAKSIAPSIYGSA 346
Cdd:COG1241 218 ---ILRIEQRTSGRGKS-TIFDLYLEANSIEVEE-----KEFEEIeiTEEDEEKIKELSKDPDIYEKIIASIAPSIYGYE 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 347 DIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRD-PQSRS 425
Cdd:COG1241 289 EIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 426 FIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNID 504
Cdd:COG1241 369 WTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPiAEQID 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 505 FMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHvnaSAAKERDIAGVPKTATTDSDgvmtmfdtdgfLTIEFLKKFVT 584
Cdd:COG1241 449 LPPTLLSRFDLIFVLRDKPDEERDRELARHILKVH---RAGELLEQEIEEETEEVKPE-----------IDPDLLRKYIA 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 585 YARLNCGPRLTPQASEKLVNHYVKMRNpvvnadafKSGKKahNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEA 664
Cdd:COG1241 515 YARRNVFPVLTEEAKDLIEDFYVDMRK--------KGEDE--DSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERA 584
|
....*..
8OUW_5 665 LRLFRVS 671
Cdd:COG1241 585 IRLVDSC 591
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
35-746 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 561.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 35 LITQFRNFIRDFSTGGFGMIYRDQLKRNYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAKIVADEITTPR 114
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 115 PKGEEKLHdiqVTLTLDEYPTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTI--PDVSIKPG--LEG 190
Cdd:NF040949 81 AEEVAKFH---VRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFewPEEEEESYeiVEP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 191 FALPRTCAAPQQgqmqrcpidpYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVGvy 270
Cdd:NF040949 158 PTVCPVCGKPGS----------FRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTG-- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 271 sIKKLIQKKGGDKSLQGIRTPYLRVlgIHMETSgpgRTNF--TTFTPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADI 348
Cdd:NF040949 226 -ILRIKPDSSLKKGSRPIFKNYIEA--NHIEVS---QKELeeVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEI 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 349 KKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSFIM 428
Cdd:NF040949 300 KEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 429 EGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNIDFMP 507
Cdd:NF040949 380 EAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSvAENIDLPP 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 508 TILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKErdiagvpktattdsdgvmtmfdtdgFLTIEFLKKFVTYAR 587
Cdd:NF040949 460 TILSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEKVKP-------------------------EIDPDLLKKYIAYAR 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 588 LNCGPRLTPQASEKLVNHYVKMRNPVVNADafksgkkAHNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRL 667
Cdd:NF040949 515 KYVRPKLTEEAKKLIEDFYVEMRKSSKSSE-------DPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRL 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 668 FRvSTIEAAA----TGNL--AGVEGFTSTADQEALNRIEVQMKKRFAIGTHVSEHLIVQDfvARQH-YRESLVKKVIDNL 740
Cdd:NF040949 588 ML-AFLESVGidveTGKIdiDTIMTGKPKSKREKMSKIVEIIKELEEEEECVKIKELIKE--AEKKgIDEEKVEELISDL 664
|
....*.
8OUW_5 741 VRRGDL 746
Cdd:NF040949 665 KRSGEI 670
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
317-539 |
5.43e-138 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 405.76 E-value: 5.43e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 317 EERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQV 396
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 397 SPIGVYTSGKGSSAAGLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTT 476
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
8OUW_5 477 LNSRCSVLAAANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVH 539
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSiAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
333-671 |
8.67e-136 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 403.65 E-value: 8.67e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 333 LIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAG 412
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 413 LTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYG 492
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 493 RWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDIAGVPKTattdsdgvmtmfdtd 571
Cdd:cd17706 161 RYNPKLSpIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQVKPEEDGIP--------------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 572 gfLTIEFLKKFVTYARlNCGPRLTPQASEKLVNHYVKMRNpvvnadafksgKKAHNSAIPITVRQLEAIVRIAESIAKME 651
Cdd:cd17706 226 --IDIELLRKYILYAR-QIHPKISEEAREKLVRWYVELRK-----------ESERRSTIPITARQLESVIRLAEAHAKMR 291
|
330 340
....*....|....*....|
8OUW_5 652 LQQFATDKHVEEALRLFRVS 671
Cdd:cd17706 292 LSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
332-669 |
3.68e-130 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 389.12 E-value: 3.68e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 332 ELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAA 411
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 412 GLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVY 491
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 492 GRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDIagvpktattdsdgvmtmfdt 570
Cdd:cd17761 161 GRFDSYRPvAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPE-------------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 571 dgfLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRnpvvnadafKSGkKAHNSAIPITVRQLEAIVRIAESIAKM 650
Cdd:cd17761 221 ---IDPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMR---------KSG-QETPSPVPITARQLEALVRLSEASARM 287
|
330
....*....|....*....
8OUW_5 651 ELQQFATDKHVEEALRLFR 669
Cdd:cd17761 288 RLSQEVTLEDAERAIRIML 306
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
334-671 |
1.98e-123 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 371.70 E-value: 1.98e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 334 IAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGL 413
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 414 TASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGR 493
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 494 WDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDiagvpktattdsdgvmtmfdtdg 572
Cdd:cd17757 162 YDRSKSlKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAIEPP----------------------- 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 573 fLTIEFLKKFVTYARLNCgPRLTPQASEKLVNHYVKMRNpvvnadafKSGKKAHNSAIPITVRQLEAIVRIAESIAKMEL 652
Cdd:cd17757 219 -FTAEQLKRYIAYARTFK-PKLTKEAKDELVEQYKELRQ--------DDASGSTRSSYRITVRQLESLIRLSEAIARLHC 288
|
330
....*....|....*....
8OUW_5 653 QQFATDKHVEEALRLFRVS 671
Cdd:cd17757 289 SDEVTPEHVEEAARLLKKS 307
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
334-667 |
8.57e-122 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 367.93 E-value: 8.57e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 334 IAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGL 413
Cdd:cd17753 2 IINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 414 TASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGR 493
Cdd:cd17753 82 TASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 494 WDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDIAGVPKTATTDSDGVMTMfdtdG 572
Cdd:cd17753 162 YNPTLTfAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEKNQRQRPKETKV----E 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 573 FLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNpvvnaDAFKSGkkahnsAIPITVRQLEAIVRIAESIAKMEL 652
Cdd:cd17753 238 PIPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRK-----ESMATG------SLPITVRHLESIIRISEAHAKMHL 306
|
330
....*....|....*
8OUW_5 653 QQFATDKHVEEALRL 667
Cdd:cd17753 307 REYVSEEDVDMAIRV 321
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
333-671 |
9.62e-120 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 362.14 E-value: 9.62e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 333 LIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITR-RGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAA 411
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKTGGKyRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 412 GLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVY 491
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 492 GRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNasaakerdiagvpktaTTDSDGVMTMFDt 570
Cdd:cd17755 161 SRYNPKLTvVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLE----------------DTPEHIQDEVLD- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 571 dgfltIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRnpvvNADAFKSGKkahnsaIPITVRQLEAIVRIAESIAKM 650
Cdd:cd17755 224 -----VEVLTDYISYAREHIHPKLSEEAAQELVQAYVDMR----KMGSDARKR------ITATPRQLESLIRLAEAHAKM 288
|
330 340
....*....|....*....|.
8OUW_5 651 ELQQFATDKHVEEALRLFRVS 671
Cdd:cd17755 289 RLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
334-671 |
2.10e-110 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 337.84 E-value: 2.10e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 334 IAKSIAPSIYGSADIKKSIACLLFGGARKKlPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGL 413
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 414 TASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGR 493
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 494 WDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAakerdiagvPKTATTdsdgvmtmfdtdg 572
Cdd:cd17758 161 YNPRRSpEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQ---------PDSDFE------------- 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 573 FLTIEFLKKFVTYARlNCGPRLTPQASEKLVNHYVKMRnpvvnADAfksgkKAHNSAIPITVRQLEAIVRIAESIAKMEL 652
Cdd:cd17758 219 PLDPKLLRAYIALAK-RKRPTVPPALADYIVQAYVEMR-----QEA-----KRSKDFTFTTPRTLLAILRLSQALARLRL 287
|
330
....*....|....*....
8OUW_5 653 QQFATDKHVEEALRLFRVS 671
Cdd:cd17758 288 SDSVEIDDVEEALRLMEMS 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
333-669 |
1.06e-105 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 325.58 E-value: 1.06e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 333 LIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAG 412
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 413 LTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYG 492
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 493 RWDESRGD-DNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNasaakerdiagvpktattdsdgvmtmfdtd 571
Cdd:cd17754 161 RYDVYKTPmENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 572 gfltIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNpvvnadaFKSGKKAHNSAIPITVRQLEAIVRIAESIAKME 651
Cdd:cd17754 211 ----IKFLRKYIHYAKERIKPKLTQEAAEYIAEEYADLRN-------DDNTKTDKARTSPITARTLETLIRLATAHAKAR 279
|
330
....*....|....*...
8OUW_5 652 LQQFATDKHVEEALRLFR 669
Cdd:cd17754 280 LSKTVDKVDAEVALNLLR 297
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
41-675 |
4.84e-84 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 286.12 E-value: 4.84e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 41 NFI----RDFSTGgfgmiyrdqlkrnyFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAKIVADEITTPR-- 114
Cdd:PTZ00111 129 NFIkenlRDHSTG--------------YSRILPFEVDLMHVYSFDKVLYKLLVTFPADCIAELDKVLVKLFNELLSKHys 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 115 -PKGEEKLHDIQVTLTLDEYPTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKhtipdvsiKPGLEGFAl 193
Cdd:PTZ00111 195 dLSLENNSFFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQK--------KIGLNDYQ- 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 194 PRTCAAPQ---QGQMQRcPI--------DPYIMLPDKCECVDYQTLKLQENPEDVPHGEMP------RHLQLFTERY--- 253
Cdd:PTZ00111 266 PCTCEHYEyviQGEVNE-PLlcnecnskYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvDNSGLNGEIYmkd 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 254 -----------LTDKVVPGNRVTIVGVYSIKKlIQKKGGDKSLQGIRTPYLRVLGIHMETSGPGRT---------NFTTF 313
Cdd:PTZ00111 345 nevinlnlyddLIDSVKTGDRVTVVGILKVTP-IRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQpekglkylgNENDF 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 314 TPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGAR-----KKLPDGITR----RGDINVLLLGDPGT 384
Cdd:PTZ00111 424 SDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGT 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 385 AKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASV-IRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQ 463
Cdd:PTZ00111 504 AKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQ 583
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 464 QTISIAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKD----ATLAKHVIEV 538
Cdd:PTZ00111 584 QTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAvIENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLP 663
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 539 HV----NASAAKERDIAGVPKTATTDSDGVMTMFDTDgfltieFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRN--- 611
Cdd:PTZ00111 664 HMtgsgNDEDTYDRSNTMHVEDESLRSEKDYNKNDLD------MLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQgnf 737
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
8OUW_5 612 PVVNADAFKSGK----------KAHNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTIEA 675
Cdd:PTZ00111 738 QTSNLDELEHAQedddddlyyqSSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQS 811
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
333-671 |
1.96e-78 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 253.61 E-value: 1.96e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 333 LIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDG--ITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSA 410
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 411 AGLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMrEDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSV 490
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKM-GSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 491 YGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIevhvnasaakerdiagvpktattdsdgvmtmfd 569
Cdd:cd17759 160 GGHYNKGKTvSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEHHQ--------------------------------- 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 570 tdgfltieFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRnpvvnadafKSGKKAHNSaiPITVRQLEAIVRIAESIAK 649
Cdd:cd17759 207 --------LLRKYISYARQYVNPVLSKDASEALQEFYLELR---------KQNQLADSS--PITTRQLESLIRLTEARAR 267
|
330 340
....*....|....*....|..
8OUW_5 650 MELQQFATDKHVEEALRLFRVS 671
Cdd:cd17759 268 LELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
333-657 |
4.33e-63 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 213.18 E-value: 4.33e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 333 LIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAG 412
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 413 LTASVIRDpqSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSvYG 492
Cdd:cd17760 81 LTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 493 RWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEvhvnasaakerdiagvPKTATTDSDGVMTMfdtd 571
Cdd:cd17760 158 QYDPNESiSVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILE----------------NKGEPSKSSKLWSM---- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 572 gfltiEFLKKFVTYARlNCGPRLTPQASEKLVNHYVKMRNpvvnadafksgKKAHNSAIpITVRQLEAIVRIAESIAKME 651
Cdd:cd17760 218 -----EKMRTYFCLIK-NLRPVLSDEANAILLRYYQLQRQ-----------SDCRNAAR-TTIRMLESLIRLAEAHARLM 279
|
....*.
8OUW_5 652 LQQFAT 657
Cdd:cd17760 280 FRETVT 285
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
136-272 |
5.51e-46 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 159.96 E-value: 5.51e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 136 SLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIPdVSIKPglegfalPRTCAAPQqgqmqrCP-IDPYI 214
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVG-VKITE-------PTKCPNPE------CGnKDPFK 66
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
8OUW_5 215 MLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVGVYSI 272
Cdd:pfam17207 67 LVHEKSKFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRV 124
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
577-672 |
1.44e-34 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 126.50 E-value: 1.44e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 577 EFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRnpvvnadafkSGKKAHNSAIPITVRQLEAIVRIAESIAKMELQQFA 656
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELR----------KESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIV 70
|
90
....*....|....*.
8OUW_5 657 TDKHVEEALRLFRVST 672
Cdd:pfam17855 71 TEEDVEEAIRLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
38-129 |
4.35e-18 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 79.64 E-value: 4.35e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 38 QFRNFIRDF-STGGFGMIYRDQLKRNYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAKIVADEItTPRPK 116
Cdd:pfam14551 3 KFKDFLEEFrEDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKEL-SEDPD 81
|
90
....*....|...
8OUW_5 117 GEEKLHDIQVTLT 129
Cdd:pfam14551 82 YAEEEKEFQVRFY 94
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
375-516 |
4.89e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 41.36 E-value: 4.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 375 NVLLLGDPGTAKSQLLKFVEQVSPIG----VYTSGkGSSAAGLtaSVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMR 450
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPgapfLYLNA-SDLLEGL--VVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLS 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
8OUW_5 451 EDDRVAIHEAMEQQTisiakagITTTLNSRCSVLAAANSvygrwdesrgDDNIDFMPTILSRFDMI 516
Cdd:cd00009 98 RGAQNALLRVLETLN-------DLRIDRENVRVIGATNR----------PLLGDLDRALYDRLDIR 146
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
375-513 |
1.14e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 39.97 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8OUW_5 375 NVLLLGDPGTAKSQLlkfVEQVS------PIGVYTSGKGSSAAGLTASviRDPQSRSFIMEGGAMVLA--DGGVVCIDEF 446
Cdd:pfam07728 1 GVLLVGPPGTGKTEL---AERLAaalsnrPVFYVQLTRDTTEEDLFGR--RNIDPGGASWVDGPLVRAarEGEIAVLDEI 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
8OUW_5 447 DKMREDDRVAIHEAMEQQTISIAKAG--ITTTLNSRcSVLAAANSVYgrwdesRGDDNIDfmPTILSRF 513
Cdd:pfam07728 76 NRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPLD------RGLNELS--PALRSRF 135
|
|
| |
