|
Name |
Accession |
Description |
Interval |
E-value |
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
1-439 |
1.61e-42 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 156.32 E-value: 1.61e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 1 MKFSNITIKNFRNFEKVNINL-DNKNVIFGMNDIGKTNFLYALRFLLDKEiRKFGFNKSDYHKHDTSKKIEIIltldlsn 79
Cdd:COG3593 1 MKLEKIKIKNFRSIKDLSIELsDDLTVLVGENNSGKSSILEALRLLLGPS-SSRKFDEEDFYLGDDPDLPEIE------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 80 yekdedtkklisvvkgartsanadvfyialeskyddkelygnIILKWGSELDNLidipgrgninaldnvfkviyinplvd 159
Cdd:COG3593 73 ------------------------------------------IELTFGSLLSRL-------------------------- 84
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 160 LDKLFAQNKKyifeesqgnesdEGILNNIKSLTDQVNQQIGEMtiikgfqQEITSEYRSLKKEEVSIELK-SEMAIKGFF 238
Cdd:COG3593 85 LRLLLKEEDK------------EELEEALEELNEELKEALKAL-------NELLSEYLKELLDGLDLELElSLDELEDLL 145
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 239 SDIIPYIKkDGDSNYYPTSGDGRRKMLSYSIYNYLAKKKYEDKIVIYLIEEPEISLHRSMQIALSKQLFEQSTYKY-FFL 317
Cdd:COG3593 146 KSLSLRIE-DGKELPLDRLGSGFQRLILLALLSALAELKRAPANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNqVII 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 318 STHSPELLYEMDNTRLIRVHSTEKVVCSSHMYNV-EEAYGSVKKKLNKALSSALFAERVLLIEGPSEKILFEKVLDEVEP 396
Cdd:COG3593 225 TTHSPHLLSEVPLENIRRLRRDSGGTTSTKLIDLdDEDLRKLLRYLGVTRSELLFARKVILVEGDTEVILLPALARKLGK 304
|
410 420 430 440
....*....|....*....|....*....|....*....|....
8TJY_E 397 EYELNGGFLLEVGGTY-FNHYVCTLNDLGITHIIKTDNDLKSKK 439
Cdd:COG3593 305 DLDEEGISIIPVGGKSnLKPLAKLLKALGIPVAVLTDGDEAGKA 348
|
|
| TOPRIM_OLD |
cd01026 |
TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the ... |
370-442 |
8.70e-14 |
|
TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family. The bacteriophage P2 OLD protein, which has DNase as well as RNase activity, consists of an N-terminal ABC-type ATPase domain and a C-terminal Toprim domain; the nuclease activity of OLD is stimulated by ATP, though the ATPase activity is not DNA-dependent. Functional details on OLD are scant and further experimentation is required to define the relationship between the ATPase and Toprim nuclease domains. The TOPRIM domain has two conserved motifs, one of which centers at a conserved glutamate and the other one at two conserved aspartates (DxD). The conserved glutamate may act as a general acid in strand cleavage by nucleases. The DXD motif may co-ordinate Mg2+, a cofactor required for full catalytic function.
Pssm-ID: 173776 Cd Length: 97 Bit Score: 67.31 E-value: 8.70e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
8TJY_E 370 LFAERVLLIEGPSEKILFEKVLDEVEPEYELNGGFLLEVGGTYFNHYVCTLNDLGITHIIKTDNDLKSKKGKK 442
Cdd:cd01026 1 FFADKVILVEGDSEEILLPALAKKLGLDLDEAGISIIPVGGKNFKPFIKLLNALGIPVAVLTDLDAKRNEKKD 73
|
|
| AAA_15 |
pfam13175 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
1-325 |
4.49e-13 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433011 [Multi-domain] Cd Length: 392 Bit Score: 71.09 E-value: 4.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 1 MKFSNITIKNFRNFEKVNINLDNK-NVIFGMNDIGKTNFLYALRFLLDKEIRKF----------GFNKSDYHKHDTSKKI 69
Cdd:pfam13175 1 MKIKSIIIKNFRCLKDTEIDLDEDlTVLIGKNNSGKSSILEALDIFLNNKEKFFeddflvlylkDVIKIDKEDLNIFENI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 70 EIILTLDLSNYEKDEDTKKLISVVKGARTSANADVFYIALESKYDDKELYGNIILKWGSEL-----DNLIDIPGRGNINA 144
Cdd:pfam13175 81 SFSIDIEIDVEFLLILFGYLEIKKKYLCLASKGKAKEYEKTLHPKGANKADLLLELKISDLkkylkQFKIYIYNNYYLDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 145 LDNVFKVIYINPLVDLDKLFAQNKKYIFEesQGNESDEGILNNIKSLTDQVNQQIGEMTIIKGFQQE------------- 211
Cdd:pfam13175 161 KKNVFDKKSKYELPSLKEEFLNSEKEEIK--VDKEDLKKLINELEKSINYHENVLENLQIKKLLISAdrnasdedsekin 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 212 --ITSEYRSLKKEEVSIELKSEMAIKGF---------------------------------FSDIIPYIKKDGDSNYYPT 256
Cdd:pfam13175 239 slLGALKQRIFEEALQEELELTEKLKETqnklkeidktlaeelknilfkkidklkdfgyppFLNPEIEIKKDDEDLPLNK 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
8TJY_E 257 SGDGRRKMLSYSIYNYLAKKKYED---KIVIYLIEEPEISLHRSMQIALSKQLFE--QSTYKYFFLSTHSPELL 325
Cdd:pfam13175 319 NGSGVQRLILLIFFIAEAERKEDEieeKNVILAIEEPEAHLHPQAQRVLIKLLKElaNDNKTQVIITTHSPHII 392
|
|
| recF |
PRK00064 |
recombination protein F; Reviewed |
1-45 |
5.26e-07 |
|
recombination protein F; Reviewed
Pssm-ID: 234608 [Multi-domain] Cd Length: 361 Bit Score: 52.08 E-value: 5.26e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*.
8TJY_E 1 MKFSNITIKNFRNFEKVNINLD-NKNVIFGMNDIGKTNFLYALRFL 45
Cdd:PRK00064 1 MYLTRLSLTDFRNYEELDLELSpGVNVLVGENGQGKTNLLEAIYLL 46
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
1-439 |
1.61e-42 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 156.32 E-value: 1.61e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 1 MKFSNITIKNFRNFEKVNINL-DNKNVIFGMNDIGKTNFLYALRFLLDKEiRKFGFNKSDYHKHDTSKKIEIIltldlsn 79
Cdd:COG3593 1 MKLEKIKIKNFRSIKDLSIELsDDLTVLVGENNSGKSSILEALRLLLGPS-SSRKFDEEDFYLGDDPDLPEIE------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 80 yekdedtkklisvvkgartsanadvfyialeskyddkelygnIILKWGSELDNLidipgrgninaldnvfkviyinplvd 159
Cdd:COG3593 73 ------------------------------------------IELTFGSLLSRL-------------------------- 84
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 160 LDKLFAQNKKyifeesqgnesdEGILNNIKSLTDQVNQQIGEMtiikgfqQEITSEYRSLKKEEVSIELK-SEMAIKGFF 238
Cdd:COG3593 85 LRLLLKEEDK------------EELEEALEELNEELKEALKAL-------NELLSEYLKELLDGLDLELElSLDELEDLL 145
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 239 SDIIPYIKkDGDSNYYPTSGDGRRKMLSYSIYNYLAKKKYEDKIVIYLIEEPEISLHRSMQIALSKQLFEQSTYKY-FFL 317
Cdd:COG3593 146 KSLSLRIE-DGKELPLDRLGSGFQRLILLALLSALAELKRAPANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNqVII 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 318 STHSPELLYEMDNTRLIRVHSTEKVVCSSHMYNV-EEAYGSVKKKLNKALSSALFAERVLLIEGPSEKILFEKVLDEVEP 396
Cdd:COG3593 225 TTHSPHLLSEVPLENIRRLRRDSGGTTSTKLIDLdDEDLRKLLRYLGVTRSELLFARKVILVEGDTEVILLPALARKLGK 304
|
410 420 430 440
....*....|....*....|....*....|....*....|....
8TJY_E 397 EYELNGGFLLEVGGTY-FNHYVCTLNDLGITHIIKTDNDLKSKK 439
Cdd:COG3593 305 DLDEEGISIIPVGGKSnLKPLAKLLKALGIPVAVLTDGDEAGKA 348
|
|
| TOPRIM_OLD |
cd01026 |
TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the ... |
370-442 |
8.70e-14 |
|
TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family. The bacteriophage P2 OLD protein, which has DNase as well as RNase activity, consists of an N-terminal ABC-type ATPase domain and a C-terminal Toprim domain; the nuclease activity of OLD is stimulated by ATP, though the ATPase activity is not DNA-dependent. Functional details on OLD are scant and further experimentation is required to define the relationship between the ATPase and Toprim nuclease domains. The TOPRIM domain has two conserved motifs, one of which centers at a conserved glutamate and the other one at two conserved aspartates (DxD). The conserved glutamate may act as a general acid in strand cleavage by nucleases. The DXD motif may co-ordinate Mg2+, a cofactor required for full catalytic function.
Pssm-ID: 173776 Cd Length: 97 Bit Score: 67.31 E-value: 8.70e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
8TJY_E 370 LFAERVLLIEGPSEKILFEKVLDEVEPEYELNGGFLLEVGGTYFNHYVCTLNDLGITHIIKTDNDLKSKKGKK 442
Cdd:cd01026 1 FFADKVILVEGDSEEILLPALAKKLGLDLDEAGISIIPVGGKNFKPFIKLLNALGIPVAVLTDLDAKRNEKKD 73
|
|
| AAA_15 |
pfam13175 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
1-325 |
4.49e-13 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433011 [Multi-domain] Cd Length: 392 Bit Score: 71.09 E-value: 4.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 1 MKFSNITIKNFRNFEKVNINLDNK-NVIFGMNDIGKTNFLYALRFLLDKEIRKF----------GFNKSDYHKHDTSKKI 69
Cdd:pfam13175 1 MKIKSIIIKNFRCLKDTEIDLDEDlTVLIGKNNSGKSSILEALDIFLNNKEKFFeddflvlylkDVIKIDKEDLNIFENI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 70 EIILTLDLSNYEKDEDTKKLISVVKGARTSANADVFYIALESKYDDKELYGNIILKWGSEL-----DNLIDIPGRGNINA 144
Cdd:pfam13175 81 SFSIDIEIDVEFLLILFGYLEIKKKYLCLASKGKAKEYEKTLHPKGANKADLLLELKISDLkkylkQFKIYIYNNYYLDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 145 LDNVFKVIYINPLVDLDKLFAQNKKYIFEesQGNESDEGILNNIKSLTDQVNQQIGEMTIIKGFQQE------------- 211
Cdd:pfam13175 161 KKNVFDKKSKYELPSLKEEFLNSEKEEIK--VDKEDLKKLINELEKSINYHENVLENLQIKKLLISAdrnasdedsekin 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 212 --ITSEYRSLKKEEVSIELKSEMAIKGF---------------------------------FSDIIPYIKKDGDSNYYPT 256
Cdd:pfam13175 239 slLGALKQRIFEEALQEELELTEKLKETqnklkeidktlaeelknilfkkidklkdfgyppFLNPEIEIKKDDEDLPLNK 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
8TJY_E 257 SGDGRRKMLSYSIYNYLAKKKYED---KIVIYLIEEPEISLHRSMQIALSKQLFE--QSTYKYFFLSTHSPELL 325
Cdd:pfam13175 319 NGSGVQRLILLIFFIAEAERKEDEieeKNVILAIEEPEAHLHPQAQRVLIKLLKElaNDNKTQVIITTHSPHII 392
|
|
| OLD-like_TOPRIM |
pfam20469 |
Overcoming lysogenization defect protein-like, TOPRIM domain; This entry represents the ... |
370-434 |
1.31e-12 |
|
Overcoming lysogenization defect protein-like, TOPRIM domain; This entry represents the topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family. The bacteriophage P2 OLD protein, which has DNase as well as RNase activity consists of an N-terminal ABC-type ATPase domain and a C-terminal Toprim domain. The nuclease activity of OLD is stimulated by ATP, though the ATPase activity is not DNA-dependent. The TOPRIM domain has two conserved motifs, one of which centres at a conserved glutamate and the other one at two conserved aspartates (DxD). The conserved glutamate may act as a general acid in strand cleavage by nucleases. The DXD motif may co-ordinate Mg2+, a cofactor required for full catalytic function.
Pssm-ID: 466618 Cd Length: 67 Bit Score: 62.79 E-value: 1.31e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
8TJY_E 370 LFAERVLLIEGPSEKILFEKVLDEV-EPEYELNGGFLLEVGG-TYFNHYVCTLNDLGITHIIKTDND 434
Cdd:pfam20469 1 FFADKVILVEGDTEEILLPALAEKLlGKDLDALGISIVSVGGkGNFKRFLKLLKALGIPVAVITDLD 67
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
6-341 |
8.98e-11 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 63.80 E-value: 8.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 6 ITIKNFRNFEKVNINLDNKNVIFGMNDIGKTNFLYALRFL-------LDKEIRKFG-----FNKSDYHKHDtskKIEIIL 73
Cdd:COG4637 5 IRIKNFKSLRDLELPLGPLTVLIGANGSGKSNLLDALRFLsdaarggLQDALARRGgleelLWRGPRTITE---PIRLEL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 74 TLDLSN-----YEkdedtkklISVvkgaRTSANADVFYIALESkyddkelygnIILKWGSELDNLIDIPGRGniNALDNV 148
Cdd:COG4637 82 EFAEEDerdlrYE--------LEL----GLPEPGGRPEVKEER----------LWLKRGSGGRPFLDFRPKG--RAVGGE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 149 FKviyinPLVDLDKLFAQnkkyiFEESQGNESDEGILNNIKS-----LTDQ---VNQQIGEMTIIKGFQQEITSEYRSLK 220
Cdd:COG4637 138 PE-----RLDSPESLLSQ-----LGDPERFPELRALREALRSwrfydFHPAplrQPQPAGRTPVLAPDGSNLAAVLATLR 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 221 KEEVSIELKSEMAIK---GFFSDIIPYIKKDGD----------SNYYPTSG--DGRRKMLSYSIYNYLAKKKyedkiVIY 285
Cdd:COG4637 208 ETHPERFERILEALRdafPGFEDIEVEPDEDGRvllefrekglDRPFPARElsDGTLRFLALLAALLSPRPP-----PLL 282
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
8TJY_E 286 LIEEPEISLHRSMQIALSKQLFEQSTYKYFFLSTHSPELLYEMDNTRLIRVHSTEK 341
Cdd:COG4637 283 CIEEPENGLHPDLLPALAELLREASERTQVIVTTHSPALLDALEPEEVLVLEREDD 338
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
25-325 |
3.40e-10 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 61.64 E-value: 3.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 25 NVIFGMNDIGKTNFLYALRFLLDKEIRKFGFNKSdyhkhDTSKKIEIILTLDLSNYEKDEDTKKLISVVKGA----RTSA 100
Cdd:pfam13304 2 NVLIGPNGSGKSNLLEALRFLADFDALVIGLTDE-----RSRNGGIGGIPSLLNGIDPKEPIEFEISEFLEDgvryRYGL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 101 NADVFYIALESKYDDKELYGNIILKWGSELDNLIDIPGRGNINALDNVFKVIYINPLVDLDKLFAQNKKYIFEE-SQGNE 179
Cdd:pfam13304 77 DLEREDVEEKLSSKPTLLEKRLLLREDSEEREPKFPPEAEELRLGLDVEERIELSLSELSDLISGLLLLSIISPlSFLLL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 180 SDEGILNNIKSLTDQVNQQIGEMTIIKGFQQ---EITSEYRSLKKEEVSIELKSEMAIKGFFSDIIPYIKKDGDSNYYPT 256
Cdd:pfam13304 157 LDEGLLLEDWAVLDLAADLALFPDLKELLQRlvrGLKLADLNLSDLGEGIEKSLLVDDRLRERGLILLENGGGGELPAFE 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 257 SGDGRRKMLSYSIYNYLAKKKYEdkivIYLIEEPEISLHRSMQIALSKQLFEQSTYKY-FFLSTHSPELL 325
Cdd:pfam13304 237 LSDGTKRLLALLAALLSALPKGG----LLLIDEPESGLHPKLLRRLLELLKELSRNGAqLILTTHSPLLL 302
|
|
| recF |
PRK00064 |
recombination protein F; Reviewed |
1-45 |
5.26e-07 |
|
recombination protein F; Reviewed
Pssm-ID: 234608 [Multi-domain] Cd Length: 361 Bit Score: 52.08 E-value: 5.26e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*.
8TJY_E 1 MKFSNITIKNFRNFEKVNINLD-NKNVIFGMNDIGKTNFLYALRFL 45
Cdd:PRK00064 1 MYLTRLSLTDFRNYEELDLELSpGVNVLVGENGQGKTNLLEAIYLL 46
|
|
| COG1106 |
COG1106 |
ATPase/GTPase, AAA15 family [General function prediction only]; |
5-325 |
5.66e-07 |
|
ATPase/GTPase, AAA15 family [General function prediction only];
Pssm-ID: 440723 [Multi-domain] Cd Length: 330 Bit Score: 51.58 E-value: 5.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 5 NITIKNFR--------NFEKVNINLDNKNVIFGMNDIGKTNFLYALRFLLD---------KEIRKFgFNKSDYHKHDTSk 67
Cdd:COG1106 4 SFSIENFRsfkdeltlSMVASGLRLLRVNLIYGANASGKSNLLEALYFLRNlvlnssqpgDKLVEP-FLLDSESKNEPS- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 68 KIEIILTLDLSNYEkdedtkklisvvkgartsanadvFYIAL-ESKYDDKELYgniilkwgseldnLIDIPGRGNINALD 146
Cdd:COG1106 82 EFEILFLLDGVRYE-----------------------YGFELdKERIISEWLY-------------FLSTAAQLNVPLLS 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 147 NVFKVIYINPLVDLDklfaqNKKYIFEESQGNESDEGILNNIKSLtdqvNQQIGEMTIIKGFQQEITSEYRSLKKE--EV 224
Cdd:COG1106 126 PLYDWFDNNISLDTS-----SDGLTLLLKEDESLKEELLELLKIA----DPGIEDIEVEEEEIEDLVERKLIFKHKggNV 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 225 SIELKSEmaikgffsdiipyikkdgdsnyyptsGDGRRKMLSYS--IYNYLAKKKyedkivIYLIEEPEISLHRSMQIAL 302
Cdd:COG1106 197 PLPLSEE--------------------------SDGTKRLLALAgaLLDALAKGG------VLLIDEIEASLHPSLLRKL 244
|
330 340
....*....|....*....|....*
8TJY_E 303 SKQLFEQSTYK--YFFLSTHSPELL 325
Cdd:COG1106 245 LKLFLDLANKNnaQLIFTTHSTELL 269
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-81 |
5.60e-06 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 47.31 E-value: 5.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 2 KFSNITIKNFRNF-EKVNINLDNK-NVIFGMNDIGKTNFLYALRFLLDKEIRKFGFNKSDY-HKHDTSKKIEIILTLDLS 78
Cdd:COG0419 1 KLLRLRLENFRSYrDTETIDFDDGlNLIVGPNGAGKSTILEAIRYALYGKARSRSKLRSDLiNVGSEEASVELEFEHGGK 80
|
...
8TJY_E 79 NYE 81
Cdd:COG0419 81 RYR 83
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1-52 |
6.36e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 6.36e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
8TJY_E 1 MKFSNITIKNFRNFEKVNINLDNK-NVIFGMNDIGKTNFLYALRFLLDKEIRK 52
Cdd:COG4717 1 MKIKELEIYGFGKFRDRTIEFSPGlNVIYGPNEAGKSTLLAFIRAMLLERLEK 53
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|
| AAA_23 |
pfam13476 |
AAA domain; |
6-184 |
8.13e-05 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 43.64 E-value: 8.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 6 ITIKNFRNFEKVNINLDNK-NVIFGMNDIGKTNFLYALRFLL------DKEIRKFGFNKSDYHKHDTSKKIEIIlTLDLS 78
Cdd:pfam13476 1 LTIENFRSFRDQTIDFSKGlTLITGPNGSGKTTILDAIKLALygktsrLKRKSGGGFVKGDIRIGLEGKGKAYV-EITFE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
8TJY_E 79 NyEKDEDTKKLISVVKGARTSANADVFYIALESKYDDKELYGNIILKWGSELDNLIDIPGRGNINALDNVFKVIYINPLV 158
Cdd:pfam13476 80 N-NDGRYTYAIERSRELSKKKGKTKKKEILEILEIDELQQFISELLKSDKIILPLLVFLGQEREEEFERKEKKERLEELE 158
|
170 180
....*....|....*....|....*.
8TJY_E 159 DLDKLFAQNKKYIFEESQGNESDEGI 184
Cdd:pfam13476 159 KALEEKEDEKKLLEKLLQLKEKKKEL 184
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|
| ABC_RecF |
cd03242 |
ATP-binding cassette domain of RecF; RecF is a recombinational DNA repair ATPase that ... |
4-45 |
1.08e-04 |
|
ATP-binding cassette domain of RecF; RecF is a recombinational DNA repair ATPase that maintains replication in the presence of DNA damage. When replication is prematurely disrupted by DNA damage, several recF pathway gene products play critical roles processing the arrested replication fork, allowing it to resume and complete its task. This CD represents the nucleotide binding domain of RecF. RecF belongs to a large superfamily of ABC transporters involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases with a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213209 [Multi-domain] Cd Length: 270 Bit Score: 44.21 E-value: 1.08e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
8TJY_E 4 SNITIKNFRNFEKVNINLD-NKNVIFGMNDIGKTNFLYALRFL 45
Cdd:cd03242 2 KSLELRNFRNYAELELEFEpGVTVLVGENAQGKTNLLEAISLL 44
|
|
| DUF2813 |
pfam11398 |
Protein of unknown function (DUF2813); This entry contains YjbD from Escherichia coli, which ... |
1-74 |
1.55e-04 |
|
Protein of unknown function (DUF2813); This entry contains YjbD from Escherichia coli, which is annotated as a nucleotide triphosphate hydrolase.
Pssm-ID: 431868 [Multi-domain] Cd Length: 372 Bit Score: 44.27 E-value: 1.55e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
8TJY_E 1 MKFSNITIKNFRNFEKVNINLDNKNVIFGMNDIGKTNFLYALRFLLDKEIRKFGFNKSDYHK-----HDTSKKIEIILT 74
Cdd:pfam11398 1 MHLERIEVVGFRGINRLSLHFDQLTVLIGENAWGKSSLLDALSLLLNPTKELYQFTLDDFHQpyaieNEPTRHLQIIFT 79
|
|
| COG4938 |
COG4938 |
Predicted ATPase [General function prediction only]; |
6-50 |
3.10e-04 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443965 [Multi-domain] Cd Length: 277 Bit Score: 43.03 E-value: 3.10e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
8TJY_E 6 ITIKNFRNFEKVNINLDNKNVIFGMNDIGKTNFLYALRFLLDKEI 50
Cdd:COG4938 4 ISIKNFGPFKEAELELKPLTLLIGPNGSGKSTLIQALLLLLQSNF 48
|
|
| ABC_SMC3_euk |
cd03272 |
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ... |
5-46 |
6.81e-03 |
|
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213239 [Multi-domain] Cd Length: 243 Bit Score: 38.40 E-value: 6.81e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
8TJY_E 5 NITIKNFRNF-EKVNI-NLDNK-NVIFGMNDIGKTNFLYALRFLL 46
Cdd:cd03272 3 QVIIQGFKSYkDQTVIePFSPKhNVVVGRNGSGKSNFFAAIRFVL 47
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