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Conserved domains on  [gi|189040059|sp|A1UEY4|]
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RecName: Full=Regulatory protein RecX

Protein Classification

regulatory protein RecX( domain architecture ID 10011252)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
14-177 1.69e-46

recombination regulator RecX; Reviewed


:

Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 149.65  E-value: 1.69e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  14 PDPDSEPNREEQAHAYCLRLLTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHlYAGKGKR 93
Cdd:PRK00117   1 LEDTARRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRA-RKGYGPR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  94 ALAAELRRKGVDDEVISSSLADIDAgAERDRAERLVRDRLRREKLDDEpgsdlKVKRRLAGMLARRGYSQSMALDVVTVE 173
Cdd:PRK00117  80 RIRQELRQKGVDREIIEEALAELDI-DWEELARELARKKFRRPLPDDA-----KEKAKLVRFLARRGFSMDVIQRVLRNA 153

                 ....
gi 189040059 174 LAGE 177
Cdd:PRK00117 154 LDDE 157
 
Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
14-177 1.69e-46

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 149.65  E-value: 1.69e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  14 PDPDSEPNREEQAHAYCLRLLTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHlYAGKGKR 93
Cdd:PRK00117   1 LEDTARRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRA-RKGYGPR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  94 ALAAELRRKGVDDEVISSSLADIDAgAERDRAERLVRDRLRREKLDDEpgsdlKVKRRLAGMLARRGYSQSMALDVVTVE 173
Cdd:PRK00117  80 RIRQELRQKGVDREIIEEALAELDI-DWEELARELARKKFRRPLPDDA-----KEKAKLVRFLARRGFSMDVIQRVLRNA 153

                 ....
gi 189040059 174 LAGE 177
Cdd:PRK00117 154 LDDE 157
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
19-170 2.69e-44

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 143.78  E-value: 2.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  19 EPNREEQAHAYCLRLLTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHLYAGKGKRALAAE 98
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 189040059  99 LRRKGVDDEVISSSLADIDAGAERDRAERLVRDRLRREKlddePGSDLKVKRRLAGMLARRGYSQSMALDVV 170
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKKFGSLK----PLDPAKEKQKLARFLARRGFSSDLIRRVL 148
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
48-173 8.85e-29

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 103.44  E-value: 8.85e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059   48 LTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHLYAGKGKRALAAELRRKGVDDEVISSSLADIDagAERDRAER 127
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFD--EEEQIARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 189040059  128 LVRDRLRREKlddePGSDLKVKRRLAGMLARRGYSQSMALDVVTVE 173
Cdd:pfam02631  79 LAEKKFKRYP----AESDRKLKQKLIRFLARRGFSSEVIRAALQEE 120
 
Name Accession Description Interval E-value
recX PRK00117
recombination regulator RecX; Reviewed
14-177 1.69e-46

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 149.65  E-value: 1.69e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  14 PDPDSEPNREEQAHAYCLRLLTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHlYAGKGKR 93
Cdd:PRK00117   1 LEDTARRRMYASARARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRA-RKGYGPR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  94 ALAAELRRKGVDDEVISSSLADIDAgAERDRAERLVRDRLRREKLDDEpgsdlKVKRRLAGMLARRGYSQSMALDVVTVE 173
Cdd:PRK00117  80 RIRQELRQKGVDREIIEEALAELDI-DWEELARELARKKFRRPLPDDA-----KEKAKLVRFLARRGFSMDVIQRVLRNA 153

                 ....
gi 189040059 174 LAGE 177
Cdd:PRK00117 154 LDDE 157
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
19-170 2.69e-44

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 143.78  E-value: 2.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  19 EPNREEQAHAYCLRLLTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHLYAGKGKRALAAE 98
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 189040059  99 LRRKGVDDEVISSSLADIDAGAERDRAERLVRDRLRREKlddePGSDLKVKRRLAGMLARRGYSQSMALDVV 170
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKKFGSLK----PLDPAKEKQKLARFLARRGFSSDLIRRVL 148
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
48-173 8.85e-29

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 103.44  E-value: 8.85e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059   48 LTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHLYAGKGKRALAAELRRKGVDDEVISSSLADIDagAERDRAER 127
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFD--EEEQIARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 189040059  128 LVRDRLRREKlddePGSDLKVKRRLAGMLARRGYSQSMALDVVTVE 173
Cdd:pfam02631  79 LAEKKFKRYP----AESDRKLKQKLIRFLARRGFSSEVIRAALQEE 120
recX PRK14135
recombination regulator RecX; Provisional
23-180 3.01e-18

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 79.49  E-value: 3.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  23 EEQAHAYCLRL--LTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSRHLYAGKGKRALAAELR 100
Cdd:PRK14135  54 DQVSKGKNLALyyLSYQMRTEKEVRDYLKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLL 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059 101 RKGVDDEVISSSLADIDAGAERDRAERLVRDRLRREKlddePGSDLKVKRRLAGMLARRGYSQS---MALDVVTVELAGE 177
Cdd:PRK14135 134 QKGIEDEIIEEALSEYTEEDQIEVAQKLAEKLLKKYQ----KLPFKALKQKIIQSLLTKGFSYEvikAALEELDLEQDEE 209

                 ...
gi 189040059 178 RER 180
Cdd:PRK14135 210 EEQ 212
recX PRK14134
recombination regulator RecX; Provisional
29-166 4.58e-13

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 65.60  E-value: 4.58e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  29 YCLRLLTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAEQWVRSR-HLYagkGKRALAAELRRKGVDDE 107
Cdd:PRK14134  66 YALKYIEKSYKTEKQIKEKLYLKEYDEDAVNRVIRFLKEYNFIDDDKYCDMYIREKiNSY---GRNKIKYTLLNKGIKEN 142
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 189040059 108 VISSSLADIDAGAERDRAERLVRDRLRREKLDDEpgSDLKVKRRLAGMLARRGYSQSMA 166
Cdd:PRK14134 143 IIIEKINNIDEEKEKKVAYKLAEKKYKILILSEK--NKFKIYKKLGPYLISRGYSSNIA 199
recX PRK14137
recombination regulator RecX; Provisional
8-165 6.95e-10

recombination regulator RecX; Provisional


Pssm-ID: 172626  Cd Length: 195  Bit Score: 55.76  E-value: 6.95e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059   8 STSESGPDPDSEPNREEQAH---AYCLRLLTARARTRAELAGKLTQRGYDEPVVARVLDRLVDVGLVDDEDFAeqwvRSR 84
Cdd:PRK14137  21 TEGPVRPERRTPPTPDEAREallAYAFRALAARAMTAAELRAKLERRSEDEALVTEVLERVQELGYQDDAQVA----RAE 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189040059  85 HLYAGKGKRALAAELRRKGVDDEVISSSLADIDAGAERDRAERLVRDRLRREKLDDEPGSDlkvkrrLAGMLARRGYSQS 164
Cdd:PRK14137  97 NSRRGVGALRVRQTLRRRGVEETLIEETLAARDPQEEQQEARNLLERRWSSFARKRDPRAS------AYAFLARRGFSGA 170

                 .
gi 189040059 165 M 165
Cdd:PRK14137 171 V 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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