NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|662792|gb|AAA79866|]
View 

single-stranded DNA binding protein [bacterium]

Protein Classification

single stranded DNA-binding domain-containing protein( domain architecture ID 489)

single stranded DNA-binding domain-containing protein may bind preferentially to single-stranded DNA

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
RPA_2b-aaRSs_OBF_like super family cl09930
Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with ...
1-181 3.58e-67

Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.; This superfamily includes two oligonucleotide/oligosaccharide binding fold (OBF) domain families. One of these contains the OBF domains of the large (RPA1, 70kDa), middle (RPA2, RPA4, 32kDa) and small (RPA3, 14 kDa) subunits of human heterotrimeric Replication protein A (RPA), and similar domains. RPA is a nuclear single-strand (ss) DNA-binding protein involved in most aspects of DNA metabolism. This family includes the four OBF domains of RPA1 [DNA-binding domain (DBD)-A, DBD-B, DBD-C, and RPA1N], the OBF domain of RPA2 (RPA2 DBD-D), RPA3, and the OBF domain of RPA4. The major DNA binding activity of human RPA and Saccharomyces cerevisiae RPA appears to be associated with DBD-A and -B, of RPA1. RPA1 DBD-C shows only weak ssDNA-binding activity and is involved in trimerization. The other OBF domain family in this superfamily is the N-terminal, anticodon recognition domain of class 2b aminoacyl-tRNA synthetases (aaRSs). aaRSs catalyze the specific attachment of amino acids to their cognate tRNAs during protein biosynthesis. Class 2b aaRSs include the homodimeric aspartyl-, asparaginyl-, and lysyl-tRNA synthetases.


The actual alignment was detected with superfamily member PRK07275:

Pssm-ID: 471953 [Multi-domain]  Cd Length: 162  Bit Score: 202.43  E-value: 3.58e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:PRK07275   1 MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     81 NYENNQGQRVYVTEVVVDNFSLLESRAESDKrraqngssepshQGGASFGAPSDNAfggvdPFASASQANPQATTPTNDA 160
Cdd:PRK07275  81 NYENQQGQRVYVTEVVADNFQMLESRATREG------------GSGGSYNGGFNNA-----PSANSYSAPAQQTPNFGRD 143
                        170       180
                 ....*....|....*....|.
gi 662792    161 PNPFAASgkTEIDISDDDLPF 181
Cdd:PRK07275 144 ESPFGNS--NPMDISDDDLPF 162
 
Name Accession Description Interval E-value
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
1-181 3.58e-67

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 202.43  E-value: 3.58e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:PRK07275   1 MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     81 NYENNQGQRVYVTEVVVDNFSLLESRAESDKrraqngssepshQGGASFGAPSDNAfggvdPFASASQANPQATTPTNDA 160
Cdd:PRK07275  81 NYENQQGQRVYVTEVVADNFQMLESRATREG------------GSGGSYNGGFNNA-----PSANSYSAPAQQTPNFGRD 143
                        170       180
                 ....*....|....*....|.
gi 662792    161 PNPFAASgkTEIDISDDDLPF 181
Cdd:PRK07275 144 ESPFGNS--NPMDISDDDLPF 162
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
1-181 2.45e-62

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 189.94  E-value: 2.45e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792       1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGE--READFINAVIWRKAAENFANFTGKGALVAIEGRLQ 78
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEwkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      79 TRNYENNQGQRVYVTEVVVDNFSLLESRAEsdkrRAQNGSSEPSHQGGasfgapsDNAFGGVdpfasasqaNPQATTPTN 158
Cdd:TIGR00621  83 TRKWEDQNGQKRSKTEIIADNVQLLDLLGA----RAQGGEFSGGGGSG-------NRPQGGQ---------EQSATGKDP 142
                         170       180
                  ....*....|....*....|...
gi 662792     159 DAPNPFAASgKTEIDISDDDLPF 181
Cdd:TIGR00621 143 AQSAPQSGS-ADPIDGDDDEIPF 164
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
2-110 4.63e-51

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 159.62  E-value: 4.63e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGER--EADFINAVIWRKAAENFANFTGKGALVAIEGRLQT 79
Cdd:COG0629   1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWkdETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80
                        90       100       110
                ....*....|....*....|....*....|.
gi 662792    80 RNYENNQGQRVYVTEVVVDNFSLLESRAESD 110
Cdd:COG0629  81 RSWEDKDGQKRYTTEVVADEIQFLGSRPSGG 111
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
2-103 1.75e-43

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 140.06  E-value: 1.75e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792       2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQA-GEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRGeGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTR 80
                          90       100
                  ....*....|....*....|...
gi 662792      81 NYENNQGQRVYVTEVVVDNFSLL 103
Cdd:pfam00436  81 KYEDQEGQKRYVTEIVADEVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
5-103 1.71e-38

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 127.34  E-value: 1.71e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     5 VVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQA-GEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTRNYE 83
Cdd:cd04496   1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRDeEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSWE 80
                        90       100
                ....*....|....*....|
gi 662792    84 NNQGQRVYVTEVVVDNFSLL 103
Cdd:cd04496  81 DKDGQKRYGTEVVADRIEFL 100
 
Name Accession Description Interval E-value
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
1-181 3.58e-67

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 202.43  E-value: 3.58e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:PRK07275   1 MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     81 NYENNQGQRVYVTEVVVDNFSLLESRAESDKrraqngssepshQGGASFGAPSDNAfggvdPFASASQANPQATTPTNDA 160
Cdd:PRK07275  81 NYENQQGQRVYVTEVVADNFQMLESRATREG------------GSGGSYNGGFNNA-----PSANSYSAPAQQTPNFGRD 143
                        170       180
                 ....*....|....*....|.
gi 662792    161 PNPFAASgkTEIDISDDDLPF 181
Cdd:PRK07275 144 ESPFGNS--NPMDISDDDLPF 162
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
1-181 2.45e-62

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 189.94  E-value: 2.45e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792       1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGE--READFINAVIWRKAAENFANFTGKGALVAIEGRLQ 78
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEwkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      79 TRNYENNQGQRVYVTEVVVDNFSLLESRAEsdkrRAQNGSSEPSHQGGasfgapsDNAFGGVdpfasasqaNPQATTPTN 158
Cdd:TIGR00621  83 TRKWEDQNGQKRSKTEIIADNVQLLDLLGA----RAQGGEFSGGGGSG-------NRPQGGQ---------EQSATGKDP 142
                         170       180
                  ....*....|....*....|...
gi 662792     159 DAPNPFAASgKTEIDISDDDLPF 181
Cdd:TIGR00621 143 AQSAPQSGS-ADPIDGDDDEIPF 164
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
1-181 6.79e-53

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 166.51  E-value: 6.79e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:PRK06751   1 MMNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQGEREADFINCVIWRKQAENVANYLKKGSLAGVDGRLQTR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     81 NYENNQGQRVYVTEVVVDNFSLLESRAESDKRRAqNGSSEPShqgGASFGAPSDNAFGGVDPFASASQANPQATTPTNDa 160
Cdd:PRK06751  81 NYEGQDGKRVYVTEVLAESVQFLEPRNGGGEQRG-SFNQQPS---GAGFGNQSSNPFGQSSNSGNQGNQGNSGFTKNDD- 155
                        170       180
                 ....*....|....*....|.
gi 662792    161 pnPFAASGKTeIDISDDDLPF 181
Cdd:PRK06751 156 --PFSNVGQP-IDISDDDLPF 173
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
2-110 4.63e-51

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 159.62  E-value: 4.63e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGER--EADFINAVIWRKAAENFANFTGKGALVAIEGRLQT 79
Cdd:COG0629   1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWkdETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80
                        90       100       110
                ....*....|....*....|....*....|.
gi 662792    80 RNYENNQGQRVYVTEVVVDNFSLLESRAESD 110
Cdd:COG0629  81 RSWEDKDGQKRYTTEVVADEIQFLGSRPSGG 111
PRK06752 PRK06752
single-stranded DNA-binding protein; Validated
1-108 1.26e-45

single-stranded DNA-binding protein; Validated


Pssm-ID: 168660  Cd Length: 112  Bit Score: 145.95  E-value: 1.26e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:PRK06752   1 MMNRVVLIGRLTKEPELYYTKQGVAYARVCVAVNRGFRNSLGEQQVDFINCVVWRKSAENVTEYCTKGSLVGITGRIHTR 80
                         90       100
                 ....*....|....*....|....*...
gi 662792     81 NYENNQGQRVYVTEVVVDNFSLLESRAE 108
Cdd:PRK06752  81 NYEDDQGKRIYITEVVIESITFLERRRE 108
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
2-103 1.75e-43

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 140.06  E-value: 1.75e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792       2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQA-GEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRGeGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTR 80
                          90       100
                  ....*....|....*....|...
gi 662792      81 NYENNQGQRVYVTEVVVDNFSLL 103
Cdd:pfam00436  81 KYEDQEGQKRYVTEIVADEVQFL 103
PRK07274 PRK07274
single-stranded DNA-binding protein; Provisional
1-108 1.82e-39

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180914  Cd Length: 131  Bit Score: 130.65  E-value: 1.82e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTR 80
Cdd:PRK07274   1 MYNKVILIGRLTATPELVKTANDKSVARVTLAVNRRFKNQNGEREADFINVVLWGKLAETLASYASKGSLISIDGELRTR 80
                         90       100
                 ....*....|....*....|....*...
gi 662792     81 NYENNqGQRVYVTEVVVDNFSLLESRAE 108
Cdd:PRK07274  81 KYEKD-GQTHYVTEVLCQSFQLLESRAQ 107
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
5-103 1.71e-38

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 127.34  E-value: 1.71e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     5 VVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQA-GEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTRNYE 83
Cdd:cd04496   1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRDeEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSWE 80
                        90       100
                ....*....|....*....|
gi 662792    84 NNQGQRVYVTEVVVDNFSLL 103
Cdd:cd04496  81 DKDGQKRYGTEVVADRIEFL 100
PRK08486 PRK08486
single-stranded DNA-binding protein; Provisional
1-181 3.17e-33

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236275 [Multi-domain]  Cd Length: 182  Bit Score: 116.48  E-value: 3.17e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAGER--EADFINAVIWRKAAENFANFTGKGALVAIEGRLQ 78
Cdd:PRK08486   1 MFNKVILVGNLTRDVELRYLPSGSAIATIGLATSRRFKKQDGEKgeEVCFIDIRLFGRTAEIANQYLSKGSKVLIEGRLT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     79 TRNYENNQGQRVYVTEVVVDNFSLLESRAESDKrraQNGSSEPSHQGGASFGAPSDNAFGGVDPFASASQANPQ--ATTP 156
Cdd:PRK08486  81 FESWMDQNGQKRSKHTITAESMQMLDSKSDNPQ---ANAMQDNSFHENFNNNYPGNYNNPSQDPYMNQAQSYNQnaYAKE 157
                        170       180
                 ....*....|....*....|....*
gi 662792    157 TNDAPNPFAASGKTEIDISDDDLPF 181
Cdd:PRK08486 158 NQQAQPPKYENSVPEIDIDEEEIPF 182
PRK07772 PRK07772
single-stranded DNA-binding protein; Provisional
5-181 6.22e-25

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236092 [Multi-domain]  Cd Length: 186  Bit Score: 95.10  E-value: 6.22e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      5 VVLIGRLTRDVELRYTQSGTAVGTFSLA-----VNRQfTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQT 79
Cdd:PRK07772   7 ITVVGNLTADPELRFTPSGAAVANFTVAstprtFDRQ-TNEWKDGEALFLRCSIWRQAAENVAESLTKGMRVIVTGRLKQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     80 RNYENNQGQRVYVTEVVVDNFSLLESRAESDKRRAQNGSSEPSHQGG-ASFGAPSDNAFGGVDPFASASQANPQATTPTN 158
Cdd:PRK07772  86 RSYETREGEKRTVVELEVDEIGPSLRYATAKVTRASRGGGGGGGGGGfGGGGGGSGGGGGGGGGGGAPGGGGAQASAPAD 165
                        170       180
                 ....*....|....*....|...
gi 662792    159 DAPNPFAASGktEIDISDDDLPF 181
Cdd:PRK07772 166 DPWSSAPASG--GFGGGDDEPPF 186
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
2-181 2.15e-24

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 93.45  E-value: 2.15e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTN-QAGER--EADFINAVIWRKAAENFANFTGKGALVAIEGRLQ 78
Cdd:PRK05733   5 VNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDkQSGQKveRTEWHRVSLFGKVAEIAGEYLRKGSQVYIEGKLQ 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     79 TRNYENNqGQRVYVTEVVVD---NFSLLESRAESDKRRAQNGssepshqGGASFGAPSDNAfggvdPFASASQANPQATT 155
Cdd:PRK05733  85 TREWEKD-GIKRYTTEIVVDmqgTMQLLGGRPQGDDQGGQGG-------GNYNQSAPRQQA-----QRPQQAAQQQSRPA 151
                        170       180
                 ....*....|....*....|....*.
gi 662792    156 PTNDAPNPFAasgktEIDISDDDLPF 181
Cdd:PRK05733 152 PQQPAPQPAA-----DFDSFDDDIPF 172
PRK06863 PRK06863
single-stranded DNA-binding protein; Provisional
2-181 9.79e-22

single-stranded DNA-binding protein; Provisional


Pssm-ID: 136097 [Multi-domain]  Cd Length: 168  Bit Score: 86.56  E-value: 9.79e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQ-AGERE--ADFINAVIWRKAAENFANFTGKGALVAIEGRLQ 78
Cdd:PRK06863   4 INKVIIVGHLGNDPEIRTMPNGEAVANISVATSESWTDKnTGERRevTEWHRIVFYRRQAEVAGEYLRKGSQVYVEGRLK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     79 TRNYENNQGQRVYVTEVVVDNFSLLESRAEsdkrRAQNGSSEPSHQGGASFGAPSDNAfggvDPFASASQANPQATTPTN 158
Cdd:PRK06863  84 TRKWQDQNGQDRYTTEIQGDVLQMLGGRNQ----RNAGGYGNSGPAPQQSYQAGQTNN----GNSQQASRPAPQQAAPQA 155
                        170       180
                 ....*....|....*....|...
gi 662792    159 DAPnpfaasgkteIDISDDDLPF 181
Cdd:PRK06863 156 EPP----------MDGFDDDIPF 168
PRK13732 PRK13732
single-stranded DNA-binding protein; Provisional
2-181 2.03e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 184284 [Multi-domain]  Cd Length: 175  Bit Score: 83.24  E-value: 2.03e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTN-QAGE--READFINAVIWRKAAENFANFTGKGALVAIEGRLQ 78
Cdd:PRK13732   6 INKVILVGRLGKDPEVRYIPNGGAVANLQVATSESWRDkQTGEmrEQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     79 TRNYENNQGQRvYVTEVVVDNFSLLE-------SRAESDKRRAQNGSSEPSHQggASFGAPSDNAFGgvdpfASASQANP 151
Cdd:PRK13732  86 TRSWEDNGITR-YVTEILVKTTGTMQmlgrapqQNAQPQPGPQQNGQPQSADA--TKKGGAKTKGRG-----RKAAQPEP 157
                        170       180       190
                 ....*....|....*....|....*....|
gi 662792    152 QATTPTNDAPNpfaasgkteidiSDDDLPF 181
Cdd:PRK13732 158 QPQPPEGEDYG------------FSDDIPF 175
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
2-181 9.25e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 81.43  E-value: 9.25e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTN-QAGE-RE-ADFINAVIWRKAAENFANFTGKGALVAIEGRLQ 78
Cdd:PRK09010   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkQTGEmKEqTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     79 TRNYENNQGQRVYVTEVVVD---NFSLLESRAESDKrrAQNGSSEPSHQGGasFGAPSDNAFGGvdPFASASQANPQ--- 152
Cdd:PRK09010  86 TRKWTDQSGQDRYTTEVVVNvggTMQMLGGRQGGGA--PAGGNIGGQQQGG--WGQPQQPQGGN--QFSGGAQSRPQqsa 159
                        170       180
                 ....*....|....*....|....*....
gi 662792    153 ATTPTNDAPNPFaasgkteidisDDDLPF 181
Cdd:PRK09010 160 PAAPSNEPPMDF-----------DDDIPF 177
PRK07459 PRK07459
single-stranded DNA-binding protein; Provisional
2-122 1.20e-18

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180986  Cd Length: 121  Bit Score: 77.03  E-value: 1.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQagerEADFINAVIWRKAAENFANFTGKGALVAIEGRLQTRN 81
Cdd:PRK07459   3 LNSVTLVGRAGRDPEVRYFESGSVVCNLTLAVNRRSRDD----EPDWFNLEIWGKTAQVAADYVKKGSLIGITGSLKFDR 78
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 662792     82 YEN-NQGQRVYVTEVVVDNFSLLESRAESDKRRAQNGSSEPS 122
Cdd:PRK07459  79 WTDrNTGEDRSKPVIRVDRLELLGSKRDSEGNANPSNSSEIP 120
PRK08763 PRK08763
single-stranded DNA-binding protein; Provisional
2-181 3.99e-17

single-stranded DNA-binding protein; Provisional


Pssm-ID: 181549 [Multi-domain]  Cd Length: 164  Bit Score: 74.21  E-value: 3.99e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQAG--EREADFINAVIWRKAAENFANFTGKGALVAIEGRLQT 79
Cdd:PRK08763   5 INKVILVGNLGNDPDIKYTQSGMTITRISLATTSVRKDREGntQERTEWHRVKFFGKLGEIAGEYLRKGSQCYIEGSIRY 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     80 RNYENNQGQRVYVTEVVVDNFSLLESRAESDKrrAQNGSSEPSHQggasfgaPSDNAFGGVDPFASASQANPQATTPTND 159
Cdd:PRK08763  85 DKFTGQDGQERYVTEIVADEMQMLGGRGEGGG--GGGGGIRPQRQ-------PAPRQNNGQDYAPRRQQPAPQQSAPPMD 155
                        170       180
                 ....*....|....*....|..
gi 662792    160 apnpfaasgkteiDISDDDLPF 181
Cdd:PRK08763 156 -------------DFADDDIPF 164
PRK06642 PRK06642
single-stranded DNA-binding protein; Provisional
2-123 7.68e-17

single-stranded DNA-binding protein; Provisional


Pssm-ID: 135984  Cd Length: 152  Bit Score: 73.22  E-value: 7.68e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQ-AGERE--ADFINAVIWRKAAENFA-NFTGKGALVAIEGRL 77
Cdd:PRK06642   5 LNKVILIGNVGRDPEIRTTGEGKKIINLSLATTETWKDRiTSERKerTEWHRVVIFSEGLVSVVeRYVTKGSKLYIEGSL 84
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 662792     78 QTRNYENNQGQRVYVTEVVVDNFS----LLESRaESDKRRAQNGSSEPSH 123
Cdd:PRK06642  85 QTRKWNDNSGQEKYTTEVVLQNFNsqliLLDSK-NSNNHNQDSGHSEYKH 133
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
2-181 2.78e-16

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 72.14  E-value: 2.78e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      2 INRVVLIGRLTRDVELRYTQSGTAVGTFSLAVNRQFTNQA-GER--EADFINAVIWR----KAAENFANftgKGALVAIE 74
Cdd:PRK06341   5 VNKVILIGNLGADPEIRRTQDGRPIANLRIATSETWRDRNsGERkeKTEWHRVVIFNeglcKVAEQYLK---KGAKVYIE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     75 GRLQTRNYENNQGQRVYVTEVVVDNF----SLLESRAESdkrraqngssepshqGGASFGApsDNAFGGVDPFASASQAN 150
Cdd:PRK06341  82 GQLQTRKWTDQSGVERYSTEVVLQGFnstlTMLDGRGEG---------------GGGGGGG--DDGGGGDFGSSGPSRGG 144
                        170       180       190
                 ....*....|....*....|....*....|.
gi 662792    151 PQattptndaPNPFAASGKTEIDIsDDDLPF 181
Cdd:PRK06341 145 PR--------PASSGGGGNFSRDM-DDDIPF 166
PRK06293 PRK06293
single-stranded DNA-binding protein; Provisional
5-181 5.56e-08

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180517 [Multi-domain]  Cd Length: 161  Bit Score: 49.90  E-value: 5.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      5 VVLIGRLTRDVELRYTQSGTAVGTFSLAVNrqfTNQAGEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTRNYEN 84
Cdd:PRK06293   4 GYIVGRLGADPEERMTSKGKRVVVLRLGVK---SRVGSKDETVWCRCNIWGNRYDKMLPYLKKGSGVIVAGEMSPESYVD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     85 NQGQRVYVTEVVVD--NFSLL--ESRAESDKRRAQNGSSEPSHQGGASFGAPSDNAFGGVDPFASASQANPQattptnda 160
Cdd:PRK06293  81 KDGSPQSSLVVSVDtiKFSPFgrNEGSRQPSAGEDEGQQRGYDNVSIGFEGESLDTESALDKDMYAGYGQDQ-------- 152
                        170       180
                 ....*....|....*....|.
gi 662792    161 pnpfaasgkteiDISDDDLPF 181
Cdd:PRK06293 153 ------------QYASEDVPF 161
PriB COG2965
Primosomal replication protein N [Replication, recombination and repair];
1-53 1.58e-04

Primosomal replication protein N [Replication, recombination and repair];


Pssm-ID: 442205  Cd Length: 98  Bit Score: 39.02  E-value: 1.58e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 662792     1 MINRVVLIGRLTRDVELRYTQSGTAVGTFSLA-VNRQftNQAG-EREADF-INAVI 53
Cdd:COG2965   1 MMNRLVLSGTVVERPALRYTPAGIPVLEFVLEhRSEQ--QEAGlPRQVECeIPAVA 54
PRK08182 PRK08182
single-stranded DNA-binding protein; Provisional
53-135 3.50e-04

single-stranded DNA-binding protein; Provisional


Pssm-ID: 169261  Cd Length: 148  Bit Score: 38.89  E-value: 3.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792     53 IWRKAAENFANFTGKGALVAIEGRLQTRNYENNQGQRVYVTEVVVDNFSLLESRAE----SDKRRAQNGSSEPSHQGGAS 128
Cdd:PRK08182  60 LWHRDAEHWARLYQKGMRVLVEGRMERDEWTDNEDNERVTFKVEARRVGILPYRIEsvtlSPKPAATEPEAEPKPQAAQE 139

                 ....*..
gi 662792    129 FGAPSDN 135
Cdd:PRK08182 140 STAPKEP 146
DnaE COG0587
DNA polymerase III, alpha subunit [Replication, recombination and repair];
4-92 2.77e-03

DNA polymerase III, alpha subunit [Replication, recombination and repair];


Pssm-ID: 440352 [Multi-domain]  Cd Length: 1050  Bit Score: 37.74  E-value: 2.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 662792      4 RVVLIGRLTrDVELRYTQSGTAVGTFSLavnrqftnqagEREADFINAVIWRKAAENFANFTGKGALVAIEGRLQTRNYE 83
Cdd:COG0587  973 RVRVAGLVT-SRQRPGTKKGKRMAFVTL-----------EDETGSIEVVVFPEVYERYRRLLLEDRLLLVRGKVQRRDGV 1040
                         90
                 ....*....|
gi 662792     84 NN-QGQRVYV 92
Cdd:COG0587 1041 VHlIAERIEV 1050
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH
HHS Vulnerability Disclosure