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Conserved domains on  [gi|2425025|gb|AAB91394|]
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beta-galactosidase, partial [Cloning vector M13mp18]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bgal_small_N super family cl46900
Beta galactosidase small chain; This domain comprises the small chain of dimeric ...
 1-69 9.85e-48

Beta galactosidase small chain; This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.


The actual alignment was detected with superfamily member PRK09525:

Pssm-ID: 481240 [Multi-domain]  Cd Length: 1027  Bit Score: 160.48  E-value: 9.85e-48
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2425025      1 APEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESW 69
Cdd:PRK09525   66 APEAVPESWLECDLPDADTIPVPSNWQLHGYDAPIYTNVTYPIPVNPPFVPEENPTGCYSLTFTVDESW 134
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
1-69 9.85e-48

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 160.48  E-value: 9.85e-48
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2425025      1 APEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESW 69
Cdd:PRK09525   66 APEAVPESWLECDLPDADTIPVPSNWQLHGYDAPIYTNVTYPIPVNPPFVPEENPTGCYSLTFTVDESW 134
Glyco_hydro_2_N pfam02837
Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, ...
 1-69 4.83e-29

Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.


Pssm-ID: 397120 [Multi-domain]  Cd Length: 169  Bit Score: 100.78  E-value: 4.83e-29
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2425025      1 APEAVPESWLECDLPEADTVVVPSNWQMHgydaPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESW 69
Cdd:pfam02837  15 APCGAPQSWWESALQESRTIAVPSSWNDQ----PIYTNVEYPIDFADPFIPTYNGTGWYQRTFFIPSKW 79
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
18-69 2.20e-06

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 42.82  E-value: 2.20e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 2425025   18 DTVVVPSNWQMHGYDAPiytnvtypitvnPPFVPT---ENPTGCYSLTFNVDESW 69
Cdd:COG3250  24 DPITVPGDWELDLYGLP------------DPFVGPwylYNGVGWYRRTFTVPASW 66
 
Name Accession Description Interval E-value
lacZ PRK09525
beta-galactosidase;
1-69 9.85e-48

beta-galactosidase;


Pssm-ID: 236548 [Multi-domain]  Cd Length: 1027  Bit Score: 160.48  E-value: 9.85e-48
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2425025      1 APEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESW 69
Cdd:PRK09525   66 APEAVPESWLECDLPDADTIPVPSNWQLHGYDAPIYTNVTYPIPVNPPFVPEENPTGCYSLTFTVDESW 134
Glyco_hydro_2_N pfam02837
Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, ...
 1-69 4.83e-29

Glycosyl hydrolases family 2, sugar binding domain; This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.


Pssm-ID: 397120 [Multi-domain]  Cd Length: 169  Bit Score: 100.78  E-value: 4.83e-29
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2425025      1 APEAVPESWLECDLPEADTVVVPSNWQMHgydaPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESW 69
Cdd:pfam02837  15 APCGAPQSWWESALQESRTIAVPSSWNDQ----PIYTNVEYPIDFADPFIPTYNGTGWYQRTFFIPSKW 79
ebgA PRK10340
cryptic beta-D-galactosidase subunit alpha; Reviewed
 1-69 4.16e-23

cryptic beta-D-galactosidase subunit alpha; Reviewed


Pssm-ID: 236673 [Multi-domain]  Cd Length: 1021  Bit Score: 90.12  E-value: 4.16e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2425025      1 APEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESW 69
Cdd:PRK10340   55 HPLYVPEAFTSELMSDWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVPFVPSDNPTGAYQRTFTLSDGW 123
LacZ COG3250
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];
18-69 2.20e-06

Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism];


Pssm-ID: 442481 [Multi-domain]  Cd Length: 638  Bit Score: 42.82  E-value: 2.20e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 2425025   18 DTVVVPSNWQMHGYDAPiytnvtypitvnPPFVPT---ENPTGCYSLTFNVDESW 69
Cdd:COG3250  24 DPITVPGDWELDLYGLP------------DPFVGPwylYNGVGWYRRTFTVPASW 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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