|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
291-803 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 818.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 291 VEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSqNQEVKPGSCP--ECQSAGPFEVNMEET 368
Cdd:smart00350 2 PSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQS-GRETEPTVCPprECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 369 IYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNN-YDGSLNTANGFPVFATVILANHVAKK 447
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 448 DNKVA-------VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVL 520
Cdd:smart00350 161 DYKRSfedssfsVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 521 LCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600
Cdd:smart00350 241 LCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVV 680
Cdd:smart00350 321 HEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 681 GSHVRHHPSNKEEEGlangsaaepampntygvEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMAT--- 757
Cdd:smart00350 401 DLHRYSHPEEDEAFE-----------------PPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTesr 463
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 39645238 758 GSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803
Cdd:smart00350 464 SSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
476-801 |
0e+00 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 700.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSaAEPAMPNTYGVEPL 715
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEK-NQRQRPKETKVEPI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17753 240 PQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAI 319
|
....*.
gi 39645238 796 RVMLES 801
Cdd:cd17753 320 RVMLDS 325
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
195-874 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 596.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKY 274
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 275 DRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKC--NFVLGPFCQSQNQEVKPGS- 351
Cdd:NF040949 81 AEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCgcEFEWPEEEEESYEIVEPPTv 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 352 CPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTaNG 431
Cdd:NF040949 161 CPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKK-GS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 432 FPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKH 511
Cdd:NF040949 240 RPIFKNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 512 KVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDK 591
Cdd:NF040949 320 RIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 592 MNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQ 671
Cdd:NF040949 400 MREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEER 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 672 DEMLARFVVGSHvrhhpsnKEEEGLANgsaaepampntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR 751
Cdd:NF040949 480 DRRLARHILDVH-------SGKEKVKP---------------EIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMR 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 752 KESMATGS----IPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVML----------ES-FIDTQKFSVMRSMRK 816
Cdd:NF040949 538 KSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLaflesvgidvETgKIDIDTIMTGKPKSK 617
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 39645238 817 tfarylsfrRDNNELLLFILKQLVAEQVtyqrnrfgaqqdtiEVPEKDLVDKARQINI 874
Cdd:NF040949 618 ---------REKMSKIVEIIKELEEEEE--------------CVKIKELIKEAEKKGI 652
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
194-874 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 582.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 194 EIHHRFKNFLRThvdshghNVFKERISDMCKE--NRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAmy 271
Cdd:COG1241 4 DLVDKFEEFLRR-------YKYRDEILELAQEypEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 272 pKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCN---FVLgpfcQSQNQEVK 348
Cdd:COG1241 75 -PYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGtetYVP----QTGEKLQE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 349 PGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428
Cdd:COG1241 150 PHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 429 ANgfPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG 508
Cdd:COG1241 230 KS--TIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 509 GKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQR-HPVSREWTLEAGALVLADRGVCLID 587
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRdDFGTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTV 667
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 668 DPVQDEMLARFVVGSHvrhhpSNKEEEGLANGSAAEPAMPntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMY 747
Cdd:COG1241 468 DEERDRELARHILKVH-----RAGELLEQEIEEETEEVKP------EIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFY 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 748 SDLRK-ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESF------IDTQKF---SVMRSMRKT 817
Cdd:COG1241 537 VDMRKkGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLkdvgvdPETGKFdidVIETGTSKS 616
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 39645238 818 farylsfRRDNNELLLFILKQLVAEQVTYqrnrfgaqqdtieVPEKDLVDKARQINI 874
Cdd:COG1241 617 -------QRDKMKLIKDIIKELEEESSGG-------------APIEDVIEEAEEEGI 653
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
460-683 |
2.79e-139 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 413.46 E-value: 2.79e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 460 DVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKV 539
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 540 SSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTS 619
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645238 620 LQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSH 683
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
194-804 |
8.81e-87 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 296.91 E-value: 8.81e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 194 EIHHRFKNFLRTHVDSHGHNVFKE---------------RISDMCKENRESLVVNYEDLAARE----HVLAY------FL 248
Cdd:PTZ00111 87 ELSERFTNFLKNFTEFSDVLEFKDeqqskpeytelyylwKLMNFIKENLRDHSTGYSRILPFEvdlmHVYSFdkvlykLL 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 249 PEAPAELLQIFDEAALEVVLAMYPKYDRITN------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQL 322
Cdd:PTZ00111 167 VTFPADCIAELDKVLVKLFNELLSKHYSDLSlennsfFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEI 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 323 SMVKYNC-----------NKCNF-VLGPFCQSQNQEvkPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRL 390
Cdd:PTZ00111 247 TMACFRCrgqkkiglndyQPCTCeHYEYVIQGEVNE--PLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDK 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 391 PRSKDAI--------------------LLADLVDSCKPGDEIELTGIYH------NNYDGSLNTAngFPVFATVIL---- 440
Cdd:PTZ00111 325 DGLDNSVdnsglngeiymkdnevinlnLYDDLIDSVKTGDRVTVVGILKvtpirtSTTRRTLKSL--YTYFVNVIHvkvi 402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 441 ----ANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEP------KNPGG 509
Cdd:PTZ00111 403 nstnANQPEKGLKYLGnENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfnKSPDA 482
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 510 KHKV---RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQ-RHPVSREWTLEAGALVLADRGVCL 585
Cdd:PTZ00111 483 CYKVdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCC 562
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 586 IDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRD 665
Cdd:PTZ00111 563 IDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLD 642
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 666 TVDPVQDEMLARFVVGSHVRHH--PSNKEEEGL--ANGSAAEPAMPNT---YGVEPLpqEVLKKYIIYAKERVHPKLNQM 738
Cdd:PTZ00111 643 HIDQDTDQLISLSIAKDFLLPHmtGSGNDEDTYdrSNTMHVEDESLRSekdYNKNDL--DMLRMYIKFSKLHCFPKLSDE 720
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 739 DQDKVAKMY------------------------SDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMA 794
Cdd:PTZ00111 721 AKKVITREYvkmrqgnfqtsnldelehaqedddDDLYYQSSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQA 800
|
730
....*....|....
gi 39645238 795 IRVM----LESFID 804
Cdd:PTZ00111 801 VQIVksstFQSLVD 814
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
197-287 |
2.32e-20 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 86.58 E-value: 2.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 197 HRFKNFLRT-HVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVV--LAMYPK 273
Cdd:pfam14551 2 RKFKDFLEEfREDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVkeLSEDPD 81
|
90
....*....|....
gi 39645238 274 YDRITNHIHVRISH 287
Cdd:pfam14551 82 YAEEEKEFQVRFYN 95
|
|
| MCM2_N |
pfam12619 |
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ... |
73-182 |
1.26e-15 |
|
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.
Pssm-ID: 403724 Cd Length: 148 Bit Score: 74.75 E-value: 1.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 73 IGDGMERDYRAIPELDAYEAEGLaLDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEE------- 145
Cdd:pfam12619 28 FGDNMEDDYRQNPELDRYDLDDI-DDEGDYEEMDAAERRRAEAQLNRRDRELGAARRRRPAAFLQDDDDEDDLdgdyglp 106
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 39645238 146 -RPARKRRQV-ERATEDGEED-EEMIE--SIENLEDLKGHSV 182
Cdd:pfam12619 107 iQRRRRRRHYdEDQDEDMDEDiDPFEEelSLESLADVKADSI 148
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
291-803 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 818.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 291 VEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSqNQEVKPGSCP--ECQSAGPFEVNMEET 368
Cdd:smart00350 2 PSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQS-GRETEPTVCPprECQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 369 IYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNN-YDGSLNTANGFPVFATVILANHVAKK 447
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 448 DNKVA-------VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVL 520
Cdd:smart00350 161 DYKRSfedssfsVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 521 LCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600
Cdd:smart00350 241 LCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVV 680
Cdd:smart00350 321 HEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 681 GSHVRHHPSNKEEEGlangsaaepampntygvEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMAT--- 757
Cdd:smart00350 401 DLHRYSHPEEDEAFE-----------------PPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTesr 463
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 39645238 758 GSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803
Cdd:smart00350 464 SSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
476-801 |
0e+00 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 700.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSaAEPAMPNTYGVEPL 715
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEK-NQRQRPKETKVEPI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17753 240 PQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAI 319
|
....*.
gi 39645238 796 RVMLES 801
Cdd:cd17753 320 RVMLDS 325
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
195-874 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 596.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKY 274
Cdd:NF040949 1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 275 DRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKC--NFVLGPFCQSQNQEVKPGS- 351
Cdd:NF040949 81 AEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCgcEFEWPEEEEESYEIVEPPTv 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 352 CPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTaNG 431
Cdd:NF040949 161 CPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKK-GS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 432 FPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKH 511
Cdd:NF040949 240 RPIFKNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 512 KVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDK 591
Cdd:NF040949 320 RIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 592 MNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQ 671
Cdd:NF040949 400 MREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEER 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 672 DEMLARFVVGSHvrhhpsnKEEEGLANgsaaepampntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR 751
Cdd:NF040949 480 DRRLARHILDVH-------SGKEKVKP---------------EIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMR 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 752 KESMATGS----IPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVML----------ES-FIDTQKFSVMRSMRK 816
Cdd:NF040949 538 KSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLaflesvgidvETgKIDIDTIMTGKPKSK 617
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 39645238 817 tfarylsfrRDNNELLLFILKQLVAEQVtyqrnrfgaqqdtiEVPEKDLVDKARQINI 874
Cdd:NF040949 618 ---------REKMSKIVEIIKELEEEEE--------------CVKIKELIKEAEKKGI 652
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
194-874 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 582.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 194 EIHHRFKNFLRThvdshghNVFKERISDMCKE--NRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAmy 271
Cdd:COG1241 4 DLVDKFEEFLRR-------YKYRDEILELAQEypEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 272 pKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCN---FVLgpfcQSQNQEVK 348
Cdd:COG1241 75 -PYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGtetYVP----QTGEKLQE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 349 PGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428
Cdd:COG1241 150 PHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 429 ANgfPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG 508
Cdd:COG1241 230 KS--TIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 509 GKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQR-HPVSREWTLEAGALVLADRGVCLID 587
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRdDFGTGRWTLEAGALVLADGGLACID 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTV 667
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 668 DPVQDEMLARFVVGSHvrhhpSNKEEEGLANGSAAEPAMPntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMY 747
Cdd:COG1241 468 DEERDRELARHILKVH-----RAGELLEQEIEEETEEVKP------EIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFY 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 748 SDLRK-ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESF------IDTQKF---SVMRSMRKT 817
Cdd:COG1241 537 VDMRKkGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLkdvgvdPETGKFdidVIETGTSKS 616
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 39645238 818 farylsfRRDNNELLLFILKQLVAEQVTYqrnrfgaqqdtieVPEKDLVDKARQINI 874
Cdd:COG1241 617 -------QRDKMKLIKDIIKELEEESSGG-------------APIEDVIEEAEEEGI 653
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
476-801 |
1.00e-145 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 433.69 E-value: 1.00e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGlANGSaaepampntygvePL 715
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQVKPE-EDGI-------------PI 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKeRVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17706 227 DIELLRKYILYAR-QIHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAI 305
|
....*.
gi 39645238 796 RVMLES 801
Cdd:cd17706 306 RLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
460-683 |
2.79e-139 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 413.46 E-value: 2.79e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 460 DVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKV 539
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 540 SSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTS 619
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645238 620 LQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSH 683
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
476-801 |
5.61e-125 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 380.19 E-value: 5.61e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSnkEEEGLANGSaaepampntygvepL 715
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKA--SQSQENEGE--------------I 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRK-------ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIE 788
Cdd:cd17756 225 PISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRKdvrqnelESDNRSSIPITVRQLEAIIRISESLAKMELSPIATE 304
|
330
....*....|...
gi 39645238 789 DDVNMAIRVMLES 801
Cdd:cd17756 305 KHVEEAIRLFQVS 317
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
475-799 |
4.14e-122 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 372.17 E-value: 4.14e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 475 EKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAV 554
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 555 GLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIG 634
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 635 GRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEglangsaaepampntygvep 714
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPE-------------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 715 LPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGS-IPITVRHIESMIRMAEAHARIHLRDYVIEDDVNM 793
Cdd:cd17761 221 IDPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEALVRLSEASARMRLSQEVTLEDAER 300
|
....*.
gi 39645238 794 AIRVML 799
Cdd:cd17761 301 AIRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
480-801 |
6.89e-119 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 364.06 E-value: 6.89e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 480 SIAPSIYGHEDIKRGLALALFGGEPKNPG-GKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTA 558
Cdd:cd17755 5 SIAPSIYELEDVKKGILLQLFGGTRKDFTkTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAVGLTA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 559 YVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYD 638
Cdd:cd17755 85 YVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIGSRYN 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 639 PSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGlangsaaepampntygvepLPQE 718
Cdd:cd17755 165 PKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEV-------------------LDVE 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 719 VLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRK-ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRV 797
Cdd:cd17755 226 VLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKmGSDARKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRL 305
|
....
gi 39645238 798 MLES 801
Cdd:cd17755 306 IREA 309
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
476-801 |
1.33e-117 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 360.53 E-value: 1.33e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHhpsnkeEEGLANgsaaepampntygvePL 715
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKR------EEAIEP---------------PF 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKeRVHPKLNQMDQDKVAKMYSDLRKESMATG---SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVN 792
Cdd:cd17757 220 TAEQLKRYIAYAR-TFKPKLTKEAKDELVEQYKELRQDDASGStrsSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVE 298
|
....*....
gi 39645238 793 MAIRVMLES 801
Cdd:cd17757 299 EAARLLKKS 307
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
476-798 |
1.11e-112 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 347.47 E-value: 1.11e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKhKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGM-KIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFV--VGSHVRHHPSnkeeeglangsaaepampntyGVE 713
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVtyVHQHNKQPDS---------------------DFE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 714 PLPQEVLKKYIIYAKeRVHPKLNQMDQDKVAKMYSDLRKESMATGSIP-ITVRHIESMIRMAEAHARIHLRDYVIEDDVN 792
Cdd:cd17758 219 PLDPKLLRAYIALAK-RKRPTVPPALADYIVQAYVEMRQEAKRSKDFTfTTPRTLLAILRLSQALARLRLSDSVEIDDVE 297
|
....*.
gi 39645238 793 MAIRVM 798
Cdd:cd17758 298 EALRLM 303
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
480-798 |
3.11e-105 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 327.89 E-value: 3.11e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 480 SIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAY 559
Cdd:cd17754 5 SLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGLTAA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 560 VQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDP 639
Cdd:cd17754 85 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGRYDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 640 SLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHvRHhpsnkeeeglangsaaepampntygveplpQEV 719
Cdd:cd17754 165 YKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMH-RY------------------------------IKF 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 720 LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRK----ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17754 214 LRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNddntKTDKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVAL 293
|
...
gi 39645238 796 RVM 798
Cdd:cd17754 294 NLL 296
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
194-804 |
8.81e-87 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 296.91 E-value: 8.81e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 194 EIHHRFKNFLRTHVDSHGHNVFKE---------------RISDMCKENRESLVVNYEDLAARE----HVLAY------FL 248
Cdd:PTZ00111 87 ELSERFTNFLKNFTEFSDVLEFKDeqqskpeytelyylwKLMNFIKENLRDHSTGYSRILPFEvdlmHVYSFdkvlykLL 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 249 PEAPAELLQIFDEAALEVVLAMYPKYDRITN------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQL 322
Cdd:PTZ00111 167 VTFPADCIAELDKVLVKLFNELLSKHYSDLSlennsfFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEI 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 323 SMVKYNC-----------NKCNF-VLGPFCQSQNQEvkPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRL 390
Cdd:PTZ00111 247 TMACFRCrgqkkiglndyQPCTCeHYEYVIQGEVNE--PLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDK 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 391 PRSKDAI--------------------LLADLVDSCKPGDEIELTGIYH------NNYDGSLNTAngFPVFATVIL---- 440
Cdd:PTZ00111 325 DGLDNSVdnsglngeiymkdnevinlnLYDDLIDSVKTGDRVTVVGILKvtpirtSTTRRTLKSL--YTYFVNVIHvkvi 402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 441 ----ANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEP------KNPGG 509
Cdd:PTZ00111 403 nstnANQPEKGLKYLGnENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfnKSPDA 482
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 510 KHKV---RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQ-RHPVSREWTLEAGALVLADRGVCL 585
Cdd:PTZ00111 483 CYKVdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCC 562
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 586 IDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRD 665
Cdd:PTZ00111 563 IDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLD 642
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 666 TVDPVQDEMLARFVVGSHVRHH--PSNKEEEGL--ANGSAAEPAMPNT---YGVEPLpqEVLKKYIIYAKERVHPKLNQM 738
Cdd:PTZ00111 643 HIDQDTDQLISLSIAKDFLLPHmtGSGNDEDTYdrSNTMHVEDESLRSekdYNKNDL--DMLRMYIKFSKLHCFPKLSDE 720
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 739 DQDKVAKMY------------------------SDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMA 794
Cdd:PTZ00111 721 AKKVITREYvkmrqgnfqtsnldelehaqedddDDLYYQSSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQA 800
|
730
....*....|....
gi 39645238 795 IRVM----LESFID 804
Cdd:PTZ00111 801 VQIVksstFQSLVD 814
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
477-798 |
2.51e-86 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 277.89 E-value: 2.51e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 477 IFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGL 556
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 557 TAYVQRHpvSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPiGGR 636
Cdd:cd17760 82 TVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 637 YDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHvrhhPSNKEEEGLangsaaepampntygvepLP 716
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENK----GEPSKSSKL------------------WS 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 717 QEVLKKYIIYAKERvHPKLNQmDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIR 796
Cdd:cd17760 217 MEKMRTYFCLIKNL-RPVLSD-EANAILLRYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVS 294
|
..
gi 39645238 797 VM 798
Cdd:cd17760 295 VM 296
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
477-801 |
1.51e-79 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 259.39 E-value: 1.51e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 477 IFASIAPSIYGHEDIKRGLALALFGGEPKNPGGK--HKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAV 554
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 555 GLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQdRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIG 634
Cdd:cd17759 82 GLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQ-HQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 635 GRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLArfvvgshvRHHpsnkeeeglangsaaepampntygvep 714
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLS--------EHH--------------------------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 715 lpqEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMA 794
Cdd:cd17759 206 ---QLLRKYISYARQYVNPVLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDV 282
|
....*..
gi 39645238 795 IRVMLES 801
Cdd:cd17759 283 IEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
294-418 |
5.75e-46 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 160.73 E-value: 5.75e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 294 LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQsqnqevKPGSC--PECQSAGPFEVNMEETIYQ 371
Cdd:pfam17207 2 IRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKIT------EPTKCpnPECGNKDPFKLVHEKSKFV 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 39645238 372 NYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIY 418
Cdd:pfam17207 76 DFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIY 122
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
718-802 |
1.40e-34 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 126.89 E-value: 1.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 718 EVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESM-ATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIR 796
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTgSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80
|
....*.
gi 39645238 797 VMLESF 802
Cdd:pfam17855 81 LLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
197-287 |
2.32e-20 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 86.58 E-value: 2.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 197 HRFKNFLRT-HVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVV--LAMYPK 273
Cdd:pfam14551 2 RKFKDFLEEfREDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVkeLSEDPD 81
|
90
....*....|....
gi 39645238 274 YDRITNHIHVRISH 287
Cdd:pfam14551 82 YAEEEKEFQVRFYN 95
|
|
| MCM2_N |
pfam12619 |
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ... |
73-182 |
1.26e-15 |
|
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.
Pssm-ID: 403724 Cd Length: 148 Bit Score: 74.75 E-value: 1.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 73 IGDGMERDYRAIPELDAYEAEGLaLDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEE------- 145
Cdd:pfam12619 28 FGDNMEDDYRQNPELDRYDLDDI-DDEGDYEEMDAAERRRAEAQLNRRDRELGAARRRRPAAFLQDDDDEDDLdgdyglp 106
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 39645238 146 -RPARKRRQV-ERATEDGEED-EEMIE--SIENLEDLKGHSV 182
Cdd:pfam12619 107 iQRRRRRRHYdEDQDEDMDEDiDPFEEelSLESLADVKADSI 148
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
485-659 |
3.11e-06 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 50.75 E-value: 3.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 485 IYGHEDIKRGLALALFGGEpknpggkhkvrgdiNVLLCGDPGTAKSQFLKYI----------EKVSSRAIFTTgqgASAV 554
Cdd:PRK09862 193 VIGQEQGKRGLEITAAGGH--------------NLLLIGPPGTGKTMLASRIngllpdlsneEALESAAILSL---VNAE 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 555 GLTAYVQRHPV-----SREWTL--------EAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQ 621
Cdd:PRK09862 256 SVQKQWRQRPFrsphhSASLTAmvgggaipGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITYP 335
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 39645238 622 ARCTVIAAANPI-GGRYD-------PSLTFSENVDLTEPIISRFDI 659
Cdd:PRK09862 336 ARFQLVAAMNPSpTGHYQgnhnrctPEQTLRYLNRLSGPFLDRFDL 381
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
485-659 |
1.50e-05 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 46.76 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 485 IYGHEDIKRGLALALFGGepknpggkHkvrgdiNVLLCGDPGTAKS---QFLKYI-------EKVSSRAIfttgqgASAV 554
Cdd:pfam01078 5 VKGQEQAKRALEIAAAGG--------H------NLLMIGPPGSGKTmlaKRLPGIlpplteaEALEVTAI------HSVA 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 555 GL---TAYVQRHP-VSREWTLEAGALV------------LADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVT 618
Cdd:pfam01078 65 GLggdGGLIRRRPfRAPHHSASAAALVgggsiprpgeisLAHNGVLFLDELPEFKRRVLESLRQPLEDGEITISRARAKV 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 39645238 619 SLQARCTVIAAANP--IGGRYDPSLTFSENVD--------LTEPIISRFDI 659
Cdd:pfam01078 145 TFPARFQLVAAMNPcpCGYLGDPNKRCRCSPRqirrylsrLSGPLLDRIDL 195
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
475-791 |
5.51e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 45.93 E-value: 5.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 475 EKIFASIAPSIYGHEDIKRGLALALFGGepknpggKHkvrgdinVLLCGDPGTAKSQFLKYIEKVS----SRAIFTTG-Q 549
Cdd:COG0714 4 ARLRAEIGKVYVGQEELIELVLIALLAG-------GH-------LLLEGVPGVGKTTLAKALARALglpfIRIQFTPDlL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 550 GASAVGLTAYVQRhpvSREWTLEAGALVladRGVCLIDEFdkmndqDRTSIH------EAMEQQSISIskAGIVTSLQAR 623
Cdd:COG0714 70 PSDILGTYIYDQQ---TGEFEFRPGPLF---ANVLLADEI------NRAPPKtqsallEAMEERQVTI--PGGTYKLPEP 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 624 CTVIAAANPIggryDPSLTFsenvDLTEPIISRFdilcvvrdtvdpvqdemLARFVVGshvrhHPSNKEEEGLANGSAAE 703
Cdd:COG0714 136 FLVIATQNPI----EQEGTY----PLPEAQLDRF-----------------LLKLYIG-----YPDAEEEREILRRHTGR 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 704 PampntygVEPLPQEVLKKYIIYAKE-----RVHPKLNQMDQDKVAKM--YSDLRKesmatgsiPITVRHIESMIRMAEA 776
Cdd:COG0714 186 H-------LAEVEPVLSPEELLALQElvrqvHVSEAVLDYIVDLVRATreHPDLRK--------GPSPRASIALLRAARA 250
|
330
....*....|....*
gi 39645238 777 HARIHLRDYVIEDDV 791
Cdd:COG0714 251 LALLDGRDYVTPDDV 265
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
518-657 |
3.71e-04 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 41.51 E-value: 3.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 518 NVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWT-LEAGALVLADR--GVCLIDEFDKMND 594
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTRDTTEEDLFGRRNIDPGGAsWVDGPLVRAARegEIAVLDEINRANP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645238 595 QDRTSIHEAMEQQSISISKAGIVTSLQARC-TVIAAANPIGgrydpsltFSENvDLTEPIISRF 657
Cdd:pfam07728 81 DVLNSLLSLLDERRLLLPDGGELVKAAPDGfRLIATMNPLD--------RGLN-ELSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
518-664 |
4.42e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 41.75 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 518 NVLLCGDPGTAKSQFLKYIEKVSSRAIFTT-GQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQD 596
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPGAPFlYLNASDLLEGLVVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLSRGA 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 39645238 597 RTSIHEAMEQQSISISKagivtslQARCTVIAAANPiggrydpsltfSENVDLTEPIISRFDILCVVR 664
Cdd:cd00009 101 QNALLRVLETLNDLRID-------RENVRVIGATNR-----------PLLGDLDRALYDRLDIRIVIP 150
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
518-632 |
1.83e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 518 NVLLCGDPGTAKSQFLK----YIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLE-----AGALVLADR---GVCL 585
Cdd:smart00382 4 VILIVGPPGSGKTTLARalarELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSgelrlRLALALARKlkpDVLI 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 39645238 586 IDEFDKMNDQDRtsiheAMEQQSISISKAGIVTSLQARCTVIAAANP 632
Cdd:smart00382 84 LDEITSLLDAEQ-----EALLLLLEELRLLLLLKSEKNLTVILTTND 125
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
519-659 |
2.26e-03 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 39.11 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 519 VLLCGDPGT---------AKSQFLKYIEkVSSRAIFTTGQGASAVGLTAYVQRhpvsrewtLEAGALvladrGVCLIDEF 589
Cdd:pfam00004 1 LLLYGPPGTgkttlakavAKELGAPFIE-ISGSELVSKYVGESEKRLRELFEA--------AKKLAP-----CVIFIDEI 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 39645238 590 DKMN-DQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANpiggRYDpsltfsenvDLTEPIISRFDI 659
Cdd:pfam00004 67 DALAgSRGSGGDSESRRVVNQLLTELDGFTSSNSKVIVIAATN----RPD---------KLDPALLGRFDR 124
|
|
| |
