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Conserved domains on  [gi|23273816|gb|AAH23288|]
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SLC10A7 protein [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SBF super family cl19217
Sodium Bile acid symporter family; This family consists of Na+/bile acid co-transporters. ...
 10-63 8.00e-10

Sodium Bile acid symporter family; This family consists of Na+/bile acid co-transporters. These transmembrane proteins function in the liver in the uptake of bile acids from portal blood plasma a process mediated by the co-transport of Na+. Also in the family is ARC3 from S. cerevisiae; this is a putative transmembrane protein involved in resistance to arsenic compounds.


The actual alignment was detected with superfamily member pfam13593:

Pssm-ID: 450274  Cd Length: 313  Bit Score: 52.19  E-value: 8.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 23273816    10 DWFMVGIVLAIAGAKLEPSIGVNGGPLKPEiTVSYIAVATIFFNSGLSLKTELL 63
Cdd:pfam13593   1 QWFLLGLVLAILLASLLPVFGAAGGPIRAE-YVITYGVALIFFLSGLRLSTEEL 53
 
Name Accession Description Interval E-value
SBF_like pfam13593
SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane ...
 10-63 8.00e-10

SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.


Pssm-ID: 433336  Cd Length: 313  Bit Score: 52.19  E-value: 8.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 23273816    10 DWFMVGIVLAIAGAKLEPSIGVNGGPLKPEiTVSYIAVATIFFNSGLSLKTELL 63
Cdd:pfam13593   1 QWFLLGLVLAILLASLLPVFGAAGGPIRAE-YVITYGVALIFFLSGLRLSTEEL 53
 
Name Accession Description Interval E-value
SBF_like pfam13593
SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane ...
 10-63 8.00e-10

SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.


Pssm-ID: 433336  Cd Length: 313  Bit Score: 52.19  E-value: 8.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 23273816    10 DWFMVGIVLAIAGAKLEPSIGVNGGPLKPEiTVSYIAVATIFFNSGLSLKTELL 63
Cdd:pfam13593   1 QWFLLGLVLAILLASLLPVFGAAGGPIRAE-YVITYGVALIFFLSGLRLSTEEL 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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