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Conserved domains on  [gi|127799903|gb|AAH48348|]
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STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) [Homo sapiens]

Protein Classification

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3( domain architecture ID 10494835)

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 is a catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
STT3 pfam02516
Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl ...
17-484 1.31e-169

Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.


:

Pssm-ID: 396873  Cd Length: 478  Bit Score: 494.60  E-value: 1.31e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   17 LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEG-FYKFHNWFDDRAWYPLG-RIIGGTIYPGL-M 93
Cdd:pfam02516   1 VLKLVIFAMIAGAAVSSRLFTDERGLSYIHEFDPYYNYRLTENLVNNGhFYGGLNWDDHSTYYPPGsRVDYGPLIPGLtM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   94 ITSAAIYHVLHFfhitiDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAI 173
Cdd:pfam02516  81 LTSGIINHSLDV-----SIREVCLWMPPLLGGLTAIPTYFLVREYKDDLAGLLAALLIAIAPGYLSRTVAGFYDTDMFAI 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  174 FCMLLTYYMWIKAVKTGS--ICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILS 251
Cdd:pfam02516 156 FLPLFVLFFFLKAIKTGSnqIFYAAIAALSIFLMVLAWGGYVFAYNLIPLFIFALLLMGRFELKLYIAYTFSYIIATIVI 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  252 MQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRS--KLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGR 329
Cdd:pfam02516 236 IQILFVGFQPVRSSEHMGALGIFGLLQIHAFGDVVVIvyQLSFYQFISLFQPGLFEVLGLIGPVLFALGVLGLIAPWMGR 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  330 FYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVR-LML 408
Cdd:pfam02516 316 LYSLWDTEYAKFHIPIIILVSVWLPTGWLALTFGLRFAIFTFPVGLIFTGLLLEFLAVFFIKYSVSQLYFSGVMVRlLML 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  409 VLAPVMCILSGIGVSQVLSTYMKNL------DISRPDKKSKKQQDSTYPIKN-EVASGMILVMAFFLITYTFHSTWVTSE 481
Cdd:pfam02516 396 TLLPVIAILAAYKASFVFSTYMDEEsaiykaAALSAPFKSLGLYDSLEWKGNtNRDSVVITWWDYGHILAVFADRPVTSD 475

                  ...
gi 127799903  482 AYS 484
Cdd:pfam02516 476 GGS 478
 
Name Accession Description Interval E-value
STT3 pfam02516
Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl ...
17-484 1.31e-169

Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.


Pssm-ID: 396873  Cd Length: 478  Bit Score: 494.60  E-value: 1.31e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   17 LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEG-FYKFHNWFDDRAWYPLG-RIIGGTIYPGL-M 93
Cdd:pfam02516   1 VLKLVIFAMIAGAAVSSRLFTDERGLSYIHEFDPYYNYRLTENLVNNGhFYGGLNWDDHSTYYPPGsRVDYGPLIPGLtM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   94 ITSAAIYHVLHFfhitiDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAI 173
Cdd:pfam02516  81 LTSGIINHSLDV-----SIREVCLWMPPLLGGLTAIPTYFLVREYKDDLAGLLAALLIAIAPGYLSRTVAGFYDTDMFAI 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  174 FCMLLTYYMWIKAVKTGS--ICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILS 251
Cdd:pfam02516 156 FLPLFVLFFFLKAIKTGSnqIFYAAIAALSIFLMVLAWGGYVFAYNLIPLFIFALLLMGRFELKLYIAYTFSYIIATIVI 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  252 MQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRS--KLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGR 329
Cdd:pfam02516 236 IQILFVGFQPVRSSEHMGALGIFGLLQIHAFGDVVVIvyQLSFYQFISLFQPGLFEVLGLIGPVLFALGVLGLIAPWMGR 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  330 FYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVR-LML 408
Cdd:pfam02516 316 LYSLWDTEYAKFHIPIIILVSVWLPTGWLALTFGLRFAIFTFPVGLIFTGLLLEFLAVFFIKYSVSQLYFSGVMVRlLML 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  409 VLAPVMCILSGIGVSQVLSTYMKNL------DISRPDKKSKKQQDSTYPIKN-EVASGMILVMAFFLITYTFHSTWVTSE 481
Cdd:pfam02516 396 TLLPVIAILAAYKASFVFSTYMDEEsaiykaAALSAPFKSLGLYDSLEWKGNtNRDSVVITWWDYGHILAVFADRPVTSD 475

                  ...
gi 127799903  482 AYS 484
Cdd:pfam02516 476 GGS 478
Stt3 COG1287
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, ...
10-703 4.55e-71

Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440898 [Multi-domain]  Cd Length: 774  Bit Score: 246.63  E-value: 4.55e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  10 SYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFES----VIHEFDPYFNYRTTRFLAEEGFYkfHNWFDDRAWYPLGRIIG 85
Cdd:COG1287    7 VLDKLKRLLHLPALLLILALALWIRLLPYDNVFRdggvYLGGNDPWYHLRQIEYILANGPS--TLPFDPLTWYPWGRDIG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  86 GTiYPGLMITSAAIYHVL-HFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAG 164
Cdd:COG1287   85 QF-GPLFDQLIALLALILgLGSPSQSSVYTVAAWFPPIFGALTVIPVYLLGRRLGGRKAGLLAALLLALSPGQLSRSLLG 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 165 SYDNEGIAIFCMLLTYYMWIKAVKTG------------SICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLML---- 228
Cdd:COG1287  164 FADHHVAELFFSTLAVLFLVLALKRAkrekrdlealkrPLLYAVLAGVALGLYLLTWGGYVLFVGILALFALLQLLldll 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 229 TGRFSHRIYVAYCTVYCLGTILSMQ---------ISFVGFQPVLssehmaAFGVFGLCqihAFVDYLRSKLNPQQFEVLF 299
Cdd:COG1287  244 RGRSPEYLAIVGAVSFAVAALLVLPfiprlgfsgTGLSLLQPLL------ALALAAGT---VFLAWLARELERRDLPRLY 314
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 300 RSVIsLVGFVLLTVGALLMLtgkispwTGRFYSLLDPSYAKNNI--PIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYY 377
Cdd:COG1287  315 YPAA-LVGLVAAGLALLAVL-------LPRVLAALIPGLRRFFGasALAATIAEAQPLTLSDLFSSFGIAFFLALIGLLL 386
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 378 ----CFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKnldisRPDKKSKKQQDSTYPIk 453
Cdd:COG1287  387 llyrPLRERRPELLFLLVWALFSIYAAFTQVRFLYYLAVAVAILAAIGLGELLDRLDL-----DKKKREAKKNINGVKI- 460
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 454 neVASGMILVMafFLITYTFHSTWVTSEAYSSPSIVlsarggdgsriifDDFREAYYWLRHNTPEDA-------KVMSWW 526
Cdd:COG1287  461 --LAVALIVLL--LLIPLSASIALSGGSSFGPGGIN-------------DDWIDALEWLKENTPEPGvypdgayGVLSWW 523
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 527 DYGYQITAMANRTILVDNNTWNNTHISRVgqAMASTEEKAYEIMRE-----LDVSYVLVIFGGLTGyssddinKFLWMVR 601
Cdd:COG1287  524 DYGHWITVLGERIPVANPFQQGITGAANF--LLAPSESEAEAILDAlhadgLGVRYVIVDDEMATG-------KFYAMAT 594
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 602 IGGSTDtgkhikenDYYTPTGEFRVDREGSPVLLNCLMYKmCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEA 681
Cdd:COG1287  595 WAGDPS--------DYYQTLYPPSGVTVYTERYYNTMLAR-LHLFDGSGDEAAAVSVVTVPGYVESGSSPAEAGVVTQDA 665
                        730       740
                 ....*....|....*....|..
gi 127799903 682 YTTEHWLVRIYKVKDLDNRGLS 703
Cdd:COG1287  666 ATALALGAGGNAVAALLSSIYV 687
archaeo_STT3 TIGR04154
oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family ...
20-580 1.77e-32

oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family occur, one to three members per genome, in the same species of Euryarchaeota as contain the predicted protein-sorting enzyme archaeosortase (TIGR04125) and its cognate protein-sorting signal PGF-CTERM (TIGR04126).


Pssm-ID: 275016 [Multi-domain]  Cd Length: 817  Bit Score: 134.36  E-value: 1.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   20 LLILSMAAVLSFSTRLFAVLRF----ESVIHEFDPYFNYRTTRFLAEEgfYKFHNWFDDRAWYPLGRIIG-GTIYPGLMI 94
Cdd:TIGR04154   1 IPVLLVVMLFALWIRILPYGNFisdgSVRFSGNDPWYHLRRIEYTVHN--FPNTLWFDPYTNYPYGTEVGwGPLFDQLGA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   95 TSAAIYHVLHffHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPG-YISRSVAGSYDNEGIAI 173
Cdd:TIGR04154  79 TLALIVGLGA--PSRETIETVAAFLPPLLGALTVIPVYFIGKRLGDRKTGLLAAFLLAVLPGqFLYRSLFGFVDHHIAEV 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  174 FCMLLTYYMWIKAVKTG---------------SICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRI-- 236
Cdd:TIGR04154 157 LFSTLAVLAFILALAVArehkpsledldtlkkPLLYAVLAGIALGLYLLTWPGAVLFAGIVGVFTLVQFILDLFRGRSpe 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  237 YVAYCTVYCLGTILSMQISFvGFQPVLSSEH------MAAFGVFGLCQIHAFVDYLRSKLNPQQFEVlfrsVISLVGFVL 310
Cdd:TIGR04154 237 YLAIVGAVTFAVAALLVLPF-GFTLGFSATYyslfqpLALLGVALGAVFLAGLSRFWERKDLPRYYY----PAAVAGLAA 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  311 LTVGALLMLTGKispwtgrFYSLLD--PSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVG-----------LYY 377
Cdd:TIGR04154 312 LGLAVLALLLPD-------LFSLIIngLRFFFGRTGTALTIAEAQPLFSTGGGFSLAPAWSNFGLGfllaiaglallLYR 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  378 CFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKneVA 457
Cdd:TIGR04154 385 LLRKYRPEELFLLVWSLFILYATLTQVRFEYYLAVNVAVLSAYLLGWVLDFAGRLPLRRSLKNKKDIETYQVSRIA--VI 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  458 SGMILVMAFFLitytfhstwvtseayssPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPE---------DAK------- 521
Cdd:TIGR04154 463 LLLIVILVLAY-----------------PSIWATAAQSTGPGGPNQDWVDALEWLKNNTPDtgldyygiyEEKddfpype 525
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 127799903  522 ----VMSWWDYGYQITAMANRtILVDNNTWNNthisrVGQA----MASTEEKAYEIMRELDVSYVLV 580
Cdd:TIGR04154 526 gsygVMSWWDYGHWITYIGER-IPNANPFQQG-----VPGAaaffLAQSEEEAEEILDKLGTRYVMT 586
 
Name Accession Description Interval E-value
STT3 pfam02516
Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl ...
17-484 1.31e-169

Oligosaccharyl transferase STT3 subunit; This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.


Pssm-ID: 396873  Cd Length: 478  Bit Score: 494.60  E-value: 1.31e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   17 LLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEG-FYKFHNWFDDRAWYPLG-RIIGGTIYPGL-M 93
Cdd:pfam02516   1 VLKLVIFAMIAGAAVSSRLFTDERGLSYIHEFDPYYNYRLTENLVNNGhFYGGLNWDDHSTYYPPGsRVDYGPLIPGLtM 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   94 ITSAAIYHVLHFfhitiDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAI 173
Cdd:pfam02516  81 LTSGIINHSLDV-----SIREVCLWMPPLLGGLTAIPTYFLVREYKDDLAGLLAALLIAIAPGYLSRTVAGFYDTDMFAI 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  174 FCMLLTYYMWIKAVKTGS--ICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILS 251
Cdd:pfam02516 156 FLPLFVLFFFLKAIKTGSnqIFYAAIAALSIFLMVLAWGGYVFAYNLIPLFIFALLLMGRFELKLYIAYTFSYIIATIVI 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  252 MQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRS--KLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGR 329
Cdd:pfam02516 236 IQILFVGFQPVRSSEHMGALGIFGLLQIHAFGDVVVIvyQLSFYQFISLFQPGLFEVLGLIGPVLFALGVLGLIAPWMGR 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  330 FYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVR-LML 408
Cdd:pfam02516 316 LYSLWDTEYAKFHIPIIILVSVWLPTGWLALTFGLRFAIFTFPVGLIFTGLLLEFLAVFFIKYSVSQLYFSGVMVRlLML 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  409 VLAPVMCILSGIGVSQVLSTYMKNL------DISRPDKKSKKQQDSTYPIKN-EVASGMILVMAFFLITYTFHSTWVTSE 481
Cdd:pfam02516 396 TLLPVIAILAAYKASFVFSTYMDEEsaiykaAALSAPFKSLGLYDSLEWKGNtNRDSVVITWWDYGHILAVFADRPVTSD 475

                  ...
gi 127799903  482 AYS 484
Cdd:pfam02516 476 GGS 478
Stt3 COG1287
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, ...
10-703 4.55e-71

Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440898 [Multi-domain]  Cd Length: 774  Bit Score: 246.63  E-value: 4.55e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  10 SYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFES----VIHEFDPYFNYRTTRFLAEEGFYkfHNWFDDRAWYPLGRIIG 85
Cdd:COG1287    7 VLDKLKRLLHLPALLLILALALWIRLLPYDNVFRdggvYLGGNDPWYHLRQIEYILANGPS--TLPFDPLTWYPWGRDIG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  86 GTiYPGLMITSAAIYHVL-HFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAG 164
Cdd:COG1287   85 QF-GPLFDQLIALLALILgLGSPSQSSVYTVAAWFPPIFGALTVIPVYLLGRRLGGRKAGLLAALLLALSPGQLSRSLLG 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 165 SYDNEGIAIFCMLLTYYMWIKAVKTG------------SICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLML---- 228
Cdd:COG1287  164 FADHHVAELFFSTLAVLFLVLALKRAkrekrdlealkrPLLYAVLAGVALGLYLLTWGGYVLFVGILALFALLQLLldll 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 229 TGRFSHRIYVAYCTVYCLGTILSMQ---------ISFVGFQPVLssehmaAFGVFGLCqihAFVDYLRSKLNPQQFEVLF 299
Cdd:COG1287  244 RGRSPEYLAIVGAVSFAVAALLVLPfiprlgfsgTGLSLLQPLL------ALALAAGT---VFLAWLARELERRDLPRLY 314
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 300 RSVIsLVGFVLLTVGALLMLtgkispwTGRFYSLLDPSYAKNNI--PIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYY 377
Cdd:COG1287  315 YPAA-LVGLVAAGLALLAVL-------LPRVLAALIPGLRRFFGasALAATIAEAQPLTLSDLFSSFGIAFFLALIGLLL 386
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 378 ----CFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKnldisRPDKKSKKQQDSTYPIk 453
Cdd:COG1287  387 llyrPLRERRPELLFLLVWALFSIYAAFTQVRFLYYLAVAVAILAAIGLGELLDRLDL-----DKKKREAKKNINGVKI- 460
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 454 neVASGMILVMafFLITYTFHSTWVTSEAYSSPSIVlsarggdgsriifDDFREAYYWLRHNTPEDA-------KVMSWW 526
Cdd:COG1287  461 --LAVALIVLL--LLIPLSASIALSGGSSFGPGGIN-------------DDWIDALEWLKENTPEPGvypdgayGVLSWW 523
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 527 DYGYQITAMANRTILVDNNTWNNTHISRVgqAMASTEEKAYEIMRE-----LDVSYVLVIFGGLTGyssddinKFLWMVR 601
Cdd:COG1287  524 DYGHWITVLGERIPVANPFQQGITGAANF--LLAPSESEAEAILDAlhadgLGVRYVIVDDEMATG-------KFYAMAT 594
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903 602 IGGSTDtgkhikenDYYTPTGEFRVDREGSPVLLNCLMYKmCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEA 681
Cdd:COG1287  595 WAGDPS--------DYYQTLYPPSGVTVYTERYYNTMLAR-LHLFDGSGDEAAAVSVVTVPGYVESGSSPAEAGVVTQDA 665
                        730       740
                 ....*....|....*....|..
gi 127799903 682 YTTEHWLVRIYKVKDLDNRGLS 703
Cdd:COG1287  666 ATALALGAGGNAVAALLSSIYV 687
archaeo_STT3 TIGR04154
oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family ...
20-580 1.77e-32

oligosaccharyl transferase, archaeosortase A system-associated; Members of this protein family occur, one to three members per genome, in the same species of Euryarchaeota as contain the predicted protein-sorting enzyme archaeosortase (TIGR04125) and its cognate protein-sorting signal PGF-CTERM (TIGR04126).


Pssm-ID: 275016 [Multi-domain]  Cd Length: 817  Bit Score: 134.36  E-value: 1.77e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   20 LLILSMAAVLSFSTRLFAVLRF----ESVIHEFDPYFNYRTTRFLAEEgfYKFHNWFDDRAWYPLGRIIG-GTIYPGLMI 94
Cdd:TIGR04154   1 IPVLLVVMLFALWIRILPYGNFisdgSVRFSGNDPWYHLRRIEYTVHN--FPNTLWFDPYTNYPYGTEVGwGPLFDQLGA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903   95 TSAAIYHVLHffHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPG-YISRSVAGSYDNEGIAI 173
Cdd:TIGR04154  79 TLALIVGLGA--PSRETIETVAAFLPPLLGALTVIPVYFIGKRLGDRKTGLLAAFLLAVLPGqFLYRSLFGFVDHHIAEV 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  174 FCMLLTYYMWIKAVKTG---------------SICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRI-- 236
Cdd:TIGR04154 157 LFSTLAVLAFILALAVArehkpsledldtlkkPLLYAVLAGIALGLYLLTWPGAVLFAGIVGVFTLVQFILDLFRGRSpe 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  237 YVAYCTVYCLGTILSMQISFvGFQPVLSSEH------MAAFGVFGLCQIHAFVDYLRSKLNPQQFEVlfrsVISLVGFVL 310
Cdd:TIGR04154 237 YLAIVGAVTFAVAALLVLPF-GFTLGFSATYyslfqpLALLGVALGAVFLAGLSRFWERKDLPRYYY----PAAVAGLAA 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  311 LTVGALLMLTGKispwtgrFYSLLD--PSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVG-----------LYY 377
Cdd:TIGR04154 312 LGLAVLALLLPD-------LFSLIIngLRFFFGRTGTALTIAEAQPLFSTGGGFSLAPAWSNFGLGfllaiaglallLYR 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  378 CFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKneVA 457
Cdd:TIGR04154 385 LLRKYRPEELFLLVWSLFILYATLTQVRFEYYLAVNVAVLSAYLLGWVLDFAGRLPLRRSLKNKKDIETYQVSRIA--VI 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 127799903  458 SGMILVMAFFLitytfhstwvtseayssPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPE---------DAK------- 521
Cdd:TIGR04154 463 LLLIVILVLAY-----------------PSIWATAAQSTGPGGPNQDWVDALEWLKNNTPDtgldyygiyEEKddfpype 525
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 127799903  522 ----VMSWWDYGYQITAMANRtILVDNNTWNNthisrVGQA----MASTEEKAYEIMRELDVSYVLV 580
Cdd:TIGR04154 526 gsygVMSWWDYGHWITYIGER-IPNANPFQQG-----VPGAaaffLAQSEEEAEEILDKLGTRYVMT 586
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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