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Conserved domains on  [gi|109731391|gb|AAI13738|]
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Amino-terminal enhancer of split [Homo sapiens]

Protein Classification

TLE_N domain-containing protein( domain architecture ID 10511323)

TLE_N domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TLE_N pfam03920
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor ...
 85-199 1.80e-84

Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerization.


:

Pssm-ID: 461094  Cd Length: 117  Bit Score: 247.72  E-value: 1.80e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109731391   85 LKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLS 164
Cdd:pfam03920   1 FKFTVPETCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNAICAQVIPFLS 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 109731391  165 QEHQQQVLGAIERAKQVTAPELNSIIR--QQLQAHQL 199
Cdd:pfam03920  81 QEHQQQVAQAVERAKQVTMAELNAIIGqqQQLQAQHL 117
 
Name Accession Description Interval E-value
TLE_N pfam03920
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor ...
 85-199 1.80e-84

Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerization.


Pssm-ID: 461094  Cd Length: 117  Bit Score: 247.72  E-value: 1.80e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109731391   85 LKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLS 164
Cdd:pfam03920   1 FKFTVPETCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNAICAQVIPFLS 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 109731391  165 QEHQQQVLGAIERAKQVTAPELNSIIR--QQLQAHQL 199
Cdd:pfam03920  81 QEHQQQVAQAVERAKQVTMAELNAIIGqqQQLQAQHL 117
 
Name Accession Description Interval E-value
TLE_N pfam03920
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor ...
 85-199 1.80e-84

Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerization.


Pssm-ID: 461094  Cd Length: 117  Bit Score: 247.72  E-value: 1.80e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109731391   85 LKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLS 164
Cdd:pfam03920   1 FKFTVPETCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNAICAQVIPFLS 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 109731391  165 QEHQQQVLGAIERAKQVTAPELNSIIR--QQLQAHQL 199
Cdd:pfam03920  81 QEHQQQVAQAVERAKQVTMAELNAIIGqqQQLQAQHL 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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