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Conserved domains on  [gi|116138752|gb|AAI25575|]
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Coiled-coil domain containing 11 [Mus musculus]

Protein Classification

trichohyalin-plectin-homology domain domain-containing protein( domain architecture ID 12159040)

trichohyalin-plectin-homology domain (TPH) domain-containing protein similar to meiosis-specific nuclear structural protein 1, trichoplein keratin filament-binding protein, and cilia- and flagella-associated proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 72-389 2.31e-18

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


:

Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 85.74  E-value: 2.31e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   72 RERCEELRTKLASIHEKKVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQ 151
Cdd:pfam13868   2 RENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  152 VTSIQAQRQGARRMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVgRA 231
Cdd:pfam13868  82 IEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERIL-EY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  232 LQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARK-QLMNEVMNT 310
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKaRQRQELQQA 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116138752  311 RKLQVQERLQRKLREQEELALHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQMQIAHQQQAREAEKEEERQEFEA 389
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGER 319
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 72-389 2.31e-18

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 85.74  E-value: 2.31e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   72 RERCEELRTKLASIHEKKVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQ 151
Cdd:pfam13868   2 RENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  152 VTSIQAQRQGARRMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVgRA 231
Cdd:pfam13868  82 IEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERIL-EY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  232 LQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARK-QLMNEVMNT 310
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKaRQRQELQQA 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116138752  311 RKLQVQERLQRKLREQEELALHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQMQIAHQQQAREAEKEEERQEFEA 389
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGER 319
PTZ00121 PTZ00121
MAEBL; Provisional
 9-350 1.38e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    9 EERRNKLRELLASEENEYFSEMQLKGETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQqfRERCEELRtklasiheK 88
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--AKKADEAK--------K 1490

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   89 KVVEERNAQIEFNKELKRQKLVEEhlfARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEE 168
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADE---AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  169 EARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLdlnmklvgRALQDLQDEADKKKQKREE 248
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI--------KAEELKKAEEEKKKVEQLK 1639

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  249 MGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKL-QVQERLQRKLREQE 327
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAeELKKKEAEEKKKAE 1719

                         330       340
                  ....*....|....*....|...
gi 116138752  328 ELALHEQRISESLKVLHQEDMED 350
Cdd:PTZ00121 1720 ELKKAEEENKIKAEEAKKEAEED 1742
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 45-347 3.74e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 3.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  45 RERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIhEKKVVEERNAQIEFNKELKRQKLVEEHL---FARLWEE 121
Cdd:COG1196  225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL-EAELEELRLELEELELELEEAQAEEYELlaeLARLEQD 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 122 DRLAKERREAQEEKRQRELVQNTRlgLDAQVTSIQAQRQGARRMKEEEARILEQNKAQIKREdEQEKLQKQKRRQETRSS 201
Cdd:COG1196  304 IARLEERRRELEERLEELEEELAE--LEEELEELEEELEELEEELEEAEEELEEAEAELAEA-EEALLEAEAELAEAEEE 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 202 LKKAVQDKIESMQREYREDLDLNmklvgRALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDI 281
Cdd:COG1196  381 LEELAEELLEALRAAAELAAQLE-----ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116138752 282 KAKKLAEKDRELALQRAARKQlmnEVMNTRKLQVQERLQRKLREQEELALHEQRISESLKVLHQED 347
Cdd:COG1196  456 EEEEALLELLAELLEEAALLE---AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 20-339 1.17e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    20 ASEENEYFSEMQLKGETIEEKKDKMRERTKLLREKKEKerqeFVAEKLDQQFRERCEELRTKLASIHEKKVVEERNAQIE 99
Cdd:TIGR02169  175 ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER----YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   100 FNKElKRQKLVEEHlfarlwEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEEEARILEQNKAQ 179
Cdd:TIGR02169  251 EELE-KLTEEISEL------EKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   180 IKREDEQ-----EKLQKQKRRQETRSSLKKAVQDKIESMQREYR------EDLDLNMKLVGRALQDLQDEADKKKQKREE 248
Cdd:TIGR02169  324 LAKLEAEidkllAEIEELEREIEEERKRRDKLTEEYAELKEELEdlraelEEVDKEFAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   249 MGREQkiynDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKLQVQErlQRKLREQEE 328
Cdd:TIGR02169  404 LKREL----DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE--QELYDLKEE 477

                          330
                   ....*....|.
gi 116138752   329 LALHEQRISES 339
Cdd:TIGR02169  478 YDRVEKELSKL 488
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 72-389 2.31e-18

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 85.74  E-value: 2.31e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   72 RERCEELRTKLASIHEKKVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQ 151
Cdd:pfam13868   2 RENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  152 VTSIQAQRQGARRMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVgRA 231
Cdd:pfam13868  82 IEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERIL-EY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  232 LQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARK-QLMNEVMNT 310
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKaRQRQELQQA 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116138752  311 RKLQVQERLQRKLREQEELALHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQMQIAHQQQAREAEKEEERQEFEA 389
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGER 319
PTZ00121 PTZ00121
MAEBL; Provisional
 9-350 1.38e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    9 EERRNKLRELLASEENEYFSEMQLKGETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQqfRERCEELRtklasiheK 88
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--AKKADEAK--------K 1490

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   89 KVVEERNAQIEFNKELKRQKLVEEhlfARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEE 168
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADE---AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  169 EARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLdlnmklvgRALQDLQDEADKKKQKREE 248
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI--------KAEELKKAEEEKKKVEQLK 1639

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  249 MGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKL-QVQERLQRKLREQE 327
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAeELKKKEAEEKKKAE 1719

                         330       340
                  ....*....|....*....|...
gi 116138752  328 ELALHEQRISESLKVLHQEDMED 350
Cdd:PTZ00121 1720 ELKKAEEENKIKAEEAKKEAEED 1742
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 45-347 3.74e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 3.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  45 RERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIhEKKVVEERNAQIEFNKELKRQKLVEEHL---FARLWEE 121
Cdd:COG1196  225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL-EAELEELRLELEELELELEEAQAEEYELlaeLARLEQD 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 122 DRLAKERREAQEEKRQRELVQNTRlgLDAQVTSIQAQRQGARRMKEEEARILEQNKAQIKREdEQEKLQKQKRRQETRSS 201
Cdd:COG1196  304 IARLEERRRELEERLEELEEELAE--LEEELEELEEELEELEEELEEAEEELEEAEAELAEA-EEALLEAEAELAEAEEE 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 202 LKKAVQDKIESMQREYREDLDLNmklvgRALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDI 281
Cdd:COG1196  381 LEELAEELLEALRAAAELAAQLE-----ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116138752 282 KAKKLAEKDRELALQRAARKQlmnEVMNTRKLQVQERLQRKLREQEELALHEQRISESLKVLHQED 347
Cdd:COG1196  456 EEEEALLELLAELLEEAALLE---AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 125-396 1.78e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 125 AKERREAQEEKRQREL---------VQNTRLGLDAQVTSIQAQRQGARRMKEEEARILEQNKAQIKREDEQEKlQKQKRR 195
Cdd:COG1196  212 AERYRELKEELKELEAellllklreLEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE-EAQAEE 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 196 QETRSSLKKAVQDKIESMQReyREDLDLNMKLVGRALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELN 275
Cdd:COG1196  291 YELLAELARLEQDIARLEER--RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 276 RLLEDIKAKKLAEKDRELALQRAARKQLMNEV-MNTRKLQVQERLQRKLREQEELALHEQRISESLKVLHQEDMEDFARR 354
Cdd:COG1196  369 EAEAELAEAEEELEELAEELLEALRAAAELAAqLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 116138752 355 CALAEEYRNQLQMQIAHQQQAREAEKEEERQEFEAGLAANKA 396
Cdd:COG1196  449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 55-373 5.79e-07

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 51.07  E-value: 5.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   55 KEKERQEFVAEKLDQQFRERCEELRTKLASIHEKKVVEERNAQIEFNKELKRQklveehlfarlweedrlakerREAQEE 134
Cdd:pfam13868  29 AEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQ---------------------IEEREQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  135 KRQRELVQntrlgldaqvtsiqaqrqgarrmKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQ 214
Cdd:pfam13868  88 KRQEEYEE-----------------------KLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKE 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  215 REYREDLDLNMKLVgRALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELA 294
Cdd:pfam13868 145 LEKEEEREEDERIL-EYLKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKE 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  295 LQRAARK-QLMNEVMNTRKLQVQERLQRKLREQEELALHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQMQIAHQQ 373
Cdd:pfam13868 224 REEAEKKaRQRQELQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEERE 303
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-360 5.99e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 5.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   9 EERRNKLRELLASEENEYfSEMQLKGETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQQF----RERCEELRTKLAS 84
Cdd:COG1196  252 EAELEELEAELAELEAEL-EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREleerLEELEEELAELEE 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  85 IHEKKVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEE-KRQRELVQNTRLGLDAQVTSIQAQRQGAR 163
Cdd:COG1196  331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEElEELAEELLEALRAAAELAAQLEELEEAEE 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 164 RMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALQDLQDEADKKK 243
Cdd:COG1196  411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 244 QKREEMGREQKIYNDYLMQRREEEKAQEKELNR--LLEDIKAKKLAEKDRELALQrAARKQLMNEVMNTRKLQVQERLQR 321
Cdd:COG1196  491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgaVAVLIGVEAAYEAALEAALA-AALQNIVVEDDEVAAAAIEYLKAA 569

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 116138752 322 KLREQEELALHEQRISESLKVLHQEDMEDFARRCALAEE 360
Cdd:COG1196  570 KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 9-303 1.50e-05

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 46.84  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    9 EERRNKLRELLASEENEYFSEMQLKgETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIHEK 88
Cdd:pfam13868  51 EERERALEEEEEKEEERKEERKRYR-QELEEQIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLR 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   89 KVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEE 168
Cdd:pfam13868 130 EEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAK 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  169 eaRILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALQDLQDEADKKKQKREe 248
Cdd:pfam13868 210 --LYQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRM- 286

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 116138752  249 mgREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQL 303
Cdd:pfam13868 287 --KRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEAERRERIEEERQKKL 339
PTZ00121 PTZ00121
MAEBL; Provisional
 9-296 2.89e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 2.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    9 EERRNKLRELLASEENEYFSEMQLKGETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIHEK 88
Cdd:PTZ00121 1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   89 KVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEE 168
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  169 EARILEQNK---AQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALQDLQDEADKKKQK 245
Cdd:PTZ00121 1666 EAKKAEEDKkkaEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 116138752  246 REEMGREQKIYNDYLMQRREEEKAQEkELNRLLEDIKAKKLAEKDRELALQ 296
Cdd:PTZ00121 1746 AEEAKKDEEEKKKIAHLKKEEEKKAE-EIRKEKEAVIEEELDEEDEKRRME 1795
PTZ00121 PTZ00121
MAEBL; Provisional
 10-366 4.93e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 4.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   10 ERRNKLRELLASEENEYFSEMQLKGETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIHEKK 89
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   90 VVEERNAQIEFNKELKRQKLVEEhLFARLWEEDRLAKERREAQEEKRQRElvqntrlglDAQVTSIQAQRQGARRMKEEE 169
Cdd:PTZ00121 1373 KEEAKKKADAAKKKAEEKKKADE-AKKKAEEDKKKADELKKAAAAKKKAD---------EAKKKAEEKKKADEAKKKAEE 1442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  170 ARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESmqreyrEDLDLNMKLVGRALQDLQDEADKKKQKREEM 249
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA------DEAKKKAEEAKKKADEAKKAAEAKKKADEAK 1516

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  250 GREQKIYNDYLM---QRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKLQVQERLQRKLREQ 326
Cdd:PTZ00121 1517 KAEEAKKADEAKkaeEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE 1596

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 116138752  327 EELALHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQ 366
Cdd:PTZ00121 1597 VMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVE 1636
PTZ00121 PTZ00121
MAEBL; Provisional
 9-312 5.01e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 5.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    9 EERRNKLRELLASEENEYFSEMQLKGEtieekKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRT--KLASIH 86
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKKAE-----EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeEKKKAE 1567

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   87 EKKVVEERNAQIEFNKELKRQ---KLVEEHLFARLWEEDRLAKERREAQEEKRQRELV---QNTRLGLDAQVTSIQAQRQ 160
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKaeeARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKKEAEEKK 1647

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  161 GARRMKEEEARIlEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALQDLQDEAD 240
Cdd:PTZ00121 1648 KAEELKKAEEEN-KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE 1726

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 116138752  241 KKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRK 312
Cdd:PTZ00121 1727 ENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 38-314 6.24e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 6.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   38 EEKKDKMRERTKLLREKK----EKERQEFVAEKLDQQFRERCEELRTklASIHEKKVVEERNAQIEFNKELKRQKLVEEH 113
Cdd:pfam17380 306 EEKAREVERRRKLEEAEKarqaEMDRQAAIYAEQERMAMERERELER--IRQEERKRELERIRQEEIAMEISRMRELERL 383

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  114 LFARLWEEDRLAKERREA-----QEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEEEARILEQ-NKAQIKREDEQE 187
Cdd:pfam17380 384 QMERQQKNERVRQELEAArkvkiLEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERvRLEEQERQQQVE 463

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  188 KLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALqdLQDEADKKKQKREEMGREQKIYNDYLMQRREEE 267
Cdd:pfam17380 464 RLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAM--IEEERKRKLLEKEMEERQKAIYEEERRREAEEE 541

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 116138752  268 KAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKLQ 314
Cdd:pfam17380 542 RRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKAR 588
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 20-339 1.17e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    20 ASEENEYFSEMQLKGETIEEKKDKMRERTKLLREKKEKerqeFVAEKLDQQFRERCEELRTKLASIHEKKVVEERNAQIE 99
Cdd:TIGR02169  175 ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER----YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   100 FNKElKRQKLVEEHlfarlwEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEEEARILEQNKAQ 179
Cdd:TIGR02169  251 EELE-KLTEEISEL------EKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   180 IKREDEQ-----EKLQKQKRRQETRSSLKKAVQDKIESMQREYR------EDLDLNMKLVGRALQDLQDEADKKKQKREE 248
Cdd:TIGR02169  324 LAKLEAEidkllAEIEELEREIEEERKRRDKLTEEYAELKEELEdlraelEEVDKEFAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   249 MGREQkiynDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKLQVQErlQRKLREQEE 328
Cdd:TIGR02169  404 LKREL----DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE--QELYDLKEE 477

                          330
                   ....*....|.
gi 116138752   329 LALHEQRISES 339
Cdd:TIGR02169  478 YDRVEKELSKL 488
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 69-342 5.61e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 5.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    69 QQFRERCEELRTKLASIHEKKVVEERNAQIEFNKELKRQKLVEEHLFARL------WEEDRLAKERREAQEEKRQREL-- 140
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELqeleekLEELRLEVSELEEEIEELQKELya 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   141 --------------VQNTRLGLDAQVTSIQAQRQGARRMKEEEARILEQNKAQI-----KREDEQEKLQKQKRRQETRSS 201
Cdd:TIGR02168  293 laneisrleqqkqiLRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLeelkeELESLEAELEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   202 LKKAVQDKIESMQREY---REDLDLNMKLVGRA---LQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKE-- 273
Cdd:TIGR02168  373 RLEELEEQLETLRSKVaqlELQIASLNNEIERLearLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEel 452

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116138752   274 ----------LNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKLQVQERLQRKLREQEELALHEQRISESLKV 342
Cdd:TIGR02168  453 qeelerleeaLEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV 531
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
122-330 6.06e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 6.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  122 DRLAKERREAQEEKRQRELVQntrlGLDAQVTSIQAQRQGARRMKEEEARI------LEQNKAQIKREDEQEKLQKQKRR 195
Cdd:COG4913   235 DDLERAHEALEDAREQIELLE----PIRELAERYAAARERLAELEYLRAALrlwfaqRRLELLEAELEELRAELARLEAE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  196 QETRSSLKKAVQDKIESMQREYREDldlnmklVGRALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELN 275
Cdd:COG4913   311 LERLEARLDALREELDELEAQIRGN-------GGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA 383

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 116138752  276 RLLEDIKAKKLAEKDRELALQRAARKQLmnevmnTRKLQVQERLQRKLREQEELA 330
Cdd:COG4913   384 ALRAEAAALLEALEEELEALEEALAEAE------AALRDLRRELRELEAEIASLE 432
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 5-220 9.03e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 9.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   5 VINTEERRNKLRELLASEENEyfsEMQLKGETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLAS 84
Cdd:COG1196  297 LARLEQDIARLEERRRELEER---LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  85 IHEKKVVEERNAQIEFNKELKRQKLVEEHLFARLwEEDRLAKERREAQEEKRQREL-VQNTRLGLDAQVTSIQAQRQGAR 163
Cdd:COG1196  374 LAEAEEELEELAEELLEALRAAAELAAQLEELEE-AEEALLERLERLEEELEELEEaLAELEEEEEEEEEALEEAAEEEA 452

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 116138752 164 RMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYRED 220
Cdd:COG1196  453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-370 1.48e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 1.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   9 EERRNKLRELLASEENEYFSEMQLKGETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIHEK 88
Cdd:COG1196  421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE 500

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  89 KVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAqvtsiqaqRQGARRMKEE 168
Cdd:COG1196  501 ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA--------IEYLKAAKAG 572

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 169 EARILEQNKAQIKREDEQeklqKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALQDLQDEADKKKQKREE 248
Cdd:COG1196  573 RATFLPLDKIRARAALAA----ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 249 MGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKLQVQERLQRKLREQEE 328
Cdd:COG1196  649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 116138752 329 LALHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQMQIA 370
Cdd:COG1196  729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
PTZ00121 PTZ00121
MAEBL; Provisional
 87-341 1.66e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   87 EKKVVEERNAQIEFNK--ELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQvtsiQAQRQGARR 164
Cdd:PTZ00121 1174 DAKKAEAARKAEEVRKaeELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE----EAKKAEEER 1249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  165 MKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALQDLQDEADKKKQ 244
Cdd:PTZ00121 1250 NNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  245 KREEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDIKAKKLaeKDRELALQRAARKQLMNEVMNTRKLQVQERLQRKLR 324
Cdd:PTZ00121 1330 KADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK--KKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKA 1407

                         250
                  ....*....|....*..
gi 116138752  325 EQEELALHEQRISESLK 341
Cdd:PTZ00121 1408 DELKKAAAAKKKADEAK 1424
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 76-373 2.25e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 2.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   76 EELRTKLASIHEKKVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRlakeRREAQEEKRQRELVQNTRLGLDAQVTSI 155
Cdd:pfam17380 269 EFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRR----KLEEAEKARQAEMDRQAAIYAEQERMAM 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  156 QAQRQGARRMKEEEARILEQNKAQ-------IKREDEQEKLQKQKRRQETRSSLKKAVQDKIesmQREYREDLDLNMKLV 228
Cdd:pfam17380 345 ERERELERIRQEERKRELERIRQEeiameisRMRELERLQMERQQKNERVRQELEAARKVKI---LEEERQRKIQQQKVE 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752  229 GRALQDLQDEADKKKQKREEMGREQKIYNdylMQRREEEKAQEKELNRLLEDIKAKKLAEKDRELALQRAA----RKQLM 304
Cdd:pfam17380 422 MEQIRAEQEEARQREVRRLEEERAREMER---VRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAeeqrRKILE 498

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116138752  305 NEVMNTRKLQVQERLQRKLREQEelaLHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQMQIAHQQ 373
Cdd:pfam17380 499 KELEERKQAMIEEERKRKLLEKE---MEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE 564
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 15-366 2.77e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 40.34  E-value: 2.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    15 LRELLASEENEYFSEMQLKGETIEEKKDKMRE-------RTKLLREKKEKERQEF-VAEKLDQQFRERCEELRTKLASIH 86
Cdd:pfam02463  125 LESQGISPEAYNFLVQGGKIEIIAMMKPERRLeieeeaaGSRLKRKKKEALKKLIeETENLAELIIDLEELKLQELKLKE 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    87 EKKVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMK 166
Cdd:pfam02463  205 QAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   167 EEEARILEQNKAQIKREDEQEKLQKQK-RRQETRSSLKKAVQDKIESMQREYREDLDLNMKLVGRALQDLQDEADKKKQK 245
Cdd:pfam02463  285 EEELKLLAKEEEELKSELLKLERRKVDdEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   246 REEMGREQKIYNDYLMQRREEEKAQEKELNRLLEDikaKKLAEKDRELALQRAARKQLMNEVMNTRKLQVQERLQRKLRE 325
Cdd:pfam02463  365 QEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL---KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIEL 441

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 116138752   326 QEELALHEQRISESLKVLHQEDMEDFARRCALAEEYRNQLQ 366
Cdd:pfam02463  442 KQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 121-329 3.62e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 3.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 121 EDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRS 200
Cdd:COG4942   33 QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752 201 SLKKAVQDKIES-MQREYREDLDLNMKLVGRALQDLQDEADKKKQKREEmgreqkiyndyLMQRREEEKAQEKELNRLLE 279
Cdd:COG4942  113 LYRLGRQPPLALlLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-----------LAALRAELEAERAELEALLA 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 116138752 280 DIKAKKlaekdRELALQRAARKQLMNEVmNTRKLQVQERLQRKLREQEEL 329
Cdd:COG4942  182 ELEEER-----AALEALKAERQKLLARL-EKELAELAAELAELQQEAEEL 225
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 53-346 4.20e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 39.67  E-value: 4.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    53 EKKEKERQEFvaekldQQFRERCEELRTKLASIHE--KKVVEERNAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERRE 130
Cdd:TIGR02169  170 RKKEKALEEL------EEVEENIERLDLIIDEKRQqlERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   131 AQEEKRQRELVQntrlgldaqvtsIQAQRQGARRMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAvQDKI 210
Cdd:TIGR02169  244 RQLASLEEELEK------------LTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL-ERSI 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   211 ESMQREyredldlnMKLVGRALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKELNRLLedikaKKLAEKD 290
Cdd:TIGR02169  311 AEKERE--------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR-----AELEEVD 377

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 116138752   291 RELALQRAARKQLmnevmntrklqvQERLQRKLREQEELALHEQRISESLKVLHQE 346
Cdd:TIGR02169  378 KEFAETRDELKDY------------REKLEKLKREINELKRELDRLQEELQRLSEE 421
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 39-311 7.10e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 38.90  E-value: 7.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    39 EKKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIHEKKVVEERNAQIEFNKELKRQKLVEEHLFARL 118
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   119 WE-EDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRqgARRMKEEEARILEQNKAQIKREDEQEKLQKQKRRQE 197
Cdd:TIGR02169  311 AEkERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR--DKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   198 TRSSLKKAVQDKIESMQREYREDLDLNMKLVGR------ALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQE 271
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEEladlnaAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 116138752   272 KELNRLLEDIKA--KKLAEKDRELALQRAARKQLMNEVMNTR 311
Cdd:TIGR02169  469 QELYDLKEEYDRveKELSKLQRELAEAEAQARASEERVRGGR 510
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 35-354 7.62e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.88  E-value: 7.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752    35 ETIEEKKDKMRERTKLLREKKEKERQEFVA-EKLDQQFRERCEELRTKLASIHEKKVVEERNAQIEFNKELKRQKLVEEH 113
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEElEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   114 LFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTSIQAQRQGARRMKEEEARilEQNKAQIKREDEQEKLQKQK 193
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE--EAANLRERLESLERRIAATE 837

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   194 RRQETRSSLKKAVQDKIESMQREyredldlnmklvgraLQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKE 273
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAE---------------IEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116138752   274 LNRLLEDIKakklaEKDRELALQRAARKQlMNEVMNTRKLQVQErLQRKLREQEELALHEQRISESLKVLHQEDMEDFAR 353
Cdd:TIGR02168  903 LRELESKRS-----ELRRELEELREKLAQ-LELRLEGLEVRIDN-LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975


                   .
gi 116138752   354 R 354
Cdd:TIGR02168  976 R 976
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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