|
Name |
Accession |
Description |
Interval |
E-value |
| RTX_toxin |
NF033943 |
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the ... |
45-986 |
0e+00 |
|
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the membranes of infected cells, causing host cell rupture.
Pssm-ID: 468257 [Multi-domain] Cd Length: 875 Bit Score: 1175.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 45 LILYIPKDYQASTGSSLNDLVKAAEALGIEVHRSEKNGTALAKELFGTTEKLLGFSERGIALFAPQFDKLLNKNQKLSKS 124
Cdd:NF033943 1 LILLIPKDYDGQKGNGLNDLVKAADELGIEVQREERNNTAIAKKSFGTAEKLLGLTERGVVIFAPQLDKLLQKYSKIGNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 125 LGGSSEALGQRLNKTQTALSALQSFLGTAIAGMDLDSLLRRrrnGEDVSGSELAKAGVDLAAQLVDNIASATGTVDAFAE 204
Cdd:NF033943 81 LGSSAENIGNNLGKAQTVLSTIQSFLGTALAGMELDELIKK---GEDVSQLELAKASIELINELVDNIASSNQTIDAFSE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 205 QLGKLGNALSNTR-LSGLASKLNNLPDLSLAGPGFDAVSGILSVVSASFILSNKDADAGTKAAAGIEISTKILGNIGKAV 283
Cdd:NF033943 158 QLNKLGSLLSNAKgLGGLGNKLQNLPNLSKAGLGLDVISGLLSGISAGFILADKNASTGTKVAAGFELTNQVLGNVTKAV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 284 SQYIIAQRVAAGLSTTAATGGLIGSVVALAISPLSFLNVADKFERAKQLEQYSERFKKFGYEGDSLLASFYRETGAIEAA 363
Cdd:NF033943 238 SSYILAQRVAAGLSTTGAVAALIASAVSLAISPLAFLSIADKFNRAKQLEEYSERFKKLGYDGDSLLAEFQRETGTIDAS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 364 LTTINSVLSAASAGVGAAATGSLVGAPVAALVSAITGIISGILDASKQAIFERVATKLANKIDEWEKKHGKNYFENGYDA 443
Cdd:NF033943 318 LTTINTALSAISAGVSAAAAGSLVGAPIALLVSGITGLISGILEASKQAMFEHVANKLANKIAEWEKKNGKNYFENGYDA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 444 RHSAFLEDTFELLSQYNKEYSVERVVAITQQRWDVNIGELAGITRKGSDTKSGKAYVDFFEEGKLLEKEPDRFDKKVFDP 523
Cdd:NF033943 398 RHAAFLEDNFKLLSSLNKEYQVERAVAITQQRWDENIGELAGITKNGDKISSGKAYVDYFEEGKRLEKKPDEFSKVVFDP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 524 LEGKIDLSSINKTTLLKFVTPVFTAGEEIRERKQTGKYEYMTELFVKGKEKWVVTGVQSHNAIYDYTNLIQLAIDKKGEK 603
Cdd:NF033943 478 LKGIIDISNSKKSTLLKFVTPLLTPGEESRERKQSGKYEYITKLVVNGVDKWTVKGVGNAGSVYDYSNLIQHAAIESGKY 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 604 RQVTIESHLGEKNDRIYLSSGSSIVYAGNGHDVAYYDKTDTGYLTFDGQSAQKAGEYIVTKELKADVKVLKEVVKTQDIS 683
Cdd:NF033943 558 REIRIISNLGAGNDKVFVGAGSSNIDAGEGHDRVYYSKTDTGYLTIDGTKATEAGSYTVTRELGGDVKILHEVVKEQETS 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 684 VGKRSEKLEYRDYELspFELGNGIRAKDELHSVEEIIGSNRKDKFFGSRFTDIFHGAKGDDEIYGNDGHDILYgddgndv 763
Cdd:NF033943 638 VGKRTEKIQYRDYEL--RSGGYGYTATDTLKSVEEIIGSNRNDKFKGSKFNDIFHGADGDDTIEGNDGDDRLY------- 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 764 ihggdgndhlvggngndrliggkgnnflnggdgddelqvfegqynvllGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGK 843
Cdd:NF033943 709 ------------------------------------------------GGKGDDKLYGGEGDDLLDGGEGNDYLNGGYGN 740
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 844 DIYRYSKEYGRHIIIEKGGDDDTLLLSDLSFKDVGFIRIGDDLLVNKriggtlyyHEDYNGNALTIKDWF-KEGKEGQNN 922
Cdd:NF033943 741 DIYIYRKGYGNHTIYDSGGKNDKLSLSDISLSDLTFKRVGNDLIINK--------NDNGVKNGITIKNWFkKESGNKKNH 812
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18026877 923 KIEKIVDKDGAYVLSQYLTELTAPGRGINYFNGLEEKLYYGEGYNaLPQLRKDIEQIISSTGAF 986
Cdd:NF033943 813 KIEQIIDKDGRVITSDQIDKLLKKKNGKISYILLSKLADNYNESN-LSSLANSLSKIISSAGSF 875
|
|
| RTX |
pfam02382 |
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins ... |
288-594 |
7.36e-93 |
|
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins and cytotoxins that have RTX (Repeat in ToXin repeats) pfam00353. This Pfam family represents a presumed domain which in some of these proteins.
Pssm-ID: 396797 Cd Length: 312 Bit Score: 297.87 E-value: 7.36e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 288 IAQRVAAGLSTTAATGGLIG---SVVALAISPLSFLNVADKFERAKQLEQYSERFKKFGYEGDSLLASFYRETGAIEAAL 364
Cdd:pfam02382 1 LAQRAAAGLATTGAVAVLILgitASLALAISPLEWAAFAQKFDYADDLDKLAQEFSDFGYEGDGLLAELLRGKGTIEASF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 365 TTINSVLSAASAGVGAAATGSLVGAPVAALVSAITGIISGILDASKQAIFERVATKLANKIDEWEKKhGKNYFENGYDAR 444
Cdd:pfam02382 81 YAISTALGVVSGGVSAAAAASGVGAPIALLVAGITGGISGILEASKQAMLEKVANRYAEKIRAKNNG-VQAYFENSFDAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 445 HSAFLEDTFELLSQYNKEYSVERVVAITQQRWDVNIGELAGITRKGSDTKSGKAYVDFFEEGKLLEKEPDRFDKKVFDPL 524
Cdd:pfam02382 160 HEALLEDNTKFLAELIKELNADRVIALGQQQWDANDGELAGISKLGGELKSGKAYVDAFEEGAKLEAGSWNTENIQLDAA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18026877 525 EGKIDLSSIN--KTTLLKFVTPVFTAGEEIRERKQTGKYEYMTELFVKGKEKWVVTGvQSHNAIYDYTNLIQ 594
Cdd:pfam02382 240 TGVIDISNVNgaKTQALTFTTPLLAAGTETRSRVHTGKNEYITTLKINRLKGWTIKD-GGANSTFDLSKVVQ 310
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
715-845 |
2.16e-18 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 86.11 E-value: 2.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 715 SVEEIIGSNRKDKFFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGG 794
Cdd:COG2931 93 GGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTLYGGAGNDTLDGG 172
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 18026877 795 DGDDelqvfegqynVLLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDI 845
Cdd:COG2931 173 AGND----------TLTGGAGNDTLTGGAGNDTLDGGGGDDTLGGGGGDDG 213
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
747-782 |
1.19e-09 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 54.37 E-value: 1.19e-09
10 20 30
....*....|....*....|....*....|....*.
gi 18026877 747 YGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRL 782
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| RTX_toxin |
NF033943 |
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the ... |
45-986 |
0e+00 |
|
RTX family hemolysin; RTX family toxin are secreted from the bacteria and inserted into the membranes of infected cells, causing host cell rupture.
Pssm-ID: 468257 [Multi-domain] Cd Length: 875 Bit Score: 1175.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 45 LILYIPKDYQASTGSSLNDLVKAAEALGIEVHRSEKNGTALAKELFGTTEKLLGFSERGIALFAPQFDKLLNKNQKLSKS 124
Cdd:NF033943 1 LILLIPKDYDGQKGNGLNDLVKAADELGIEVQREERNNTAIAKKSFGTAEKLLGLTERGVVIFAPQLDKLLQKYSKIGNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 125 LGGSSEALGQRLNKTQTALSALQSFLGTAIAGMDLDSLLRRrrnGEDVSGSELAKAGVDLAAQLVDNIASATGTVDAFAE 204
Cdd:NF033943 81 LGSSAENIGNNLGKAQTVLSTIQSFLGTALAGMELDELIKK---GEDVSQLELAKASIELINELVDNIASSNQTIDAFSE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 205 QLGKLGNALSNTR-LSGLASKLNNLPDLSLAGPGFDAVSGILSVVSASFILSNKDADAGTKAAAGIEISTKILGNIGKAV 283
Cdd:NF033943 158 QLNKLGSLLSNAKgLGGLGNKLQNLPNLSKAGLGLDVISGLLSGISAGFILADKNASTGTKVAAGFELTNQVLGNVTKAV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 284 SQYIIAQRVAAGLSTTAATGGLIGSVVALAISPLSFLNVADKFERAKQLEQYSERFKKFGYEGDSLLASFYRETGAIEAA 363
Cdd:NF033943 238 SSYILAQRVAAGLSTTGAVAALIASAVSLAISPLAFLSIADKFNRAKQLEEYSERFKKLGYDGDSLLAEFQRETGTIDAS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 364 LTTINSVLSAASAGVGAAATGSLVGAPVAALVSAITGIISGILDASKQAIFERVATKLANKIDEWEKKHGKNYFENGYDA 443
Cdd:NF033943 318 LTTINTALSAISAGVSAAAAGSLVGAPIALLVSGITGLISGILEASKQAMFEHVANKLANKIAEWEKKNGKNYFENGYDA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 444 RHSAFLEDTFELLSQYNKEYSVERVVAITQQRWDVNIGELAGITRKGSDTKSGKAYVDFFEEGKLLEKEPDRFDKKVFDP 523
Cdd:NF033943 398 RHAAFLEDNFKLLSSLNKEYQVERAVAITQQRWDENIGELAGITKNGDKISSGKAYVDYFEEGKRLEKKPDEFSKVVFDP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 524 LEGKIDLSSINKTTLLKFVTPVFTAGEEIRERKQTGKYEYMTELFVKGKEKWVVTGVQSHNAIYDYTNLIQLAIDKKGEK 603
Cdd:NF033943 478 LKGIIDISNSKKSTLLKFVTPLLTPGEESRERKQSGKYEYITKLVVNGVDKWTVKGVGNAGSVYDYSNLIQHAAIESGKY 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 604 RQVTIESHLGEKNDRIYLSSGSSIVYAGNGHDVAYYDKTDTGYLTFDGQSAQKAGEYIVTKELKADVKVLKEVVKTQDIS 683
Cdd:NF033943 558 REIRIISNLGAGNDKVFVGAGSSNIDAGEGHDRVYYSKTDTGYLTIDGTKATEAGSYTVTRELGGDVKILHEVVKEQETS 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 684 VGKRSEKLEYRDYELspFELGNGIRAKDELHSVEEIIGSNRKDKFFGSRFTDIFHGAKGDDEIYGNDGHDILYgddgndv 763
Cdd:NF033943 638 VGKRTEKIQYRDYEL--RSGGYGYTATDTLKSVEEIIGSNRNDKFKGSKFNDIFHGADGDDTIEGNDGDDRLY------- 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 764 ihggdgndhlvggngndrliggkgnnflnggdgddelqvfegqynvllGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGK 843
Cdd:NF033943 709 ------------------------------------------------GGKGDDKLYGGEGDDLLDGGEGNDYLNGGYGN 740
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 844 DIYRYSKEYGRHIIIEKGGDDDTLLLSDLSFKDVGFIRIGDDLLVNKriggtlyyHEDYNGNALTIKDWF-KEGKEGQNN 922
Cdd:NF033943 741 DIYIYRKGYGNHTIYDSGGKNDKLSLSDISLSDLTFKRVGNDLIINK--------NDNGVKNGITIKNWFkKESGNKKNH 812
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18026877 923 KIEKIVDKDGAYVLSQYLTELTAPGRGINYFNGLEEKLYYGEGYNaLPQLRKDIEQIISSTGAF 986
Cdd:NF033943 813 KIEQIIDKDGRVITSDQIDKLLKKKNGKISYILLSKLADNYNESN-LSSLANSLSKIISSAGSF 875
|
|
| RTX |
pfam02382 |
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins ... |
288-594 |
7.36e-93 |
|
N-terminal domain in RTX protein; The RTX family of bacterial toxins are a group of cytolysins and cytotoxins that have RTX (Repeat in ToXin repeats) pfam00353. This Pfam family represents a presumed domain which in some of these proteins.
Pssm-ID: 396797 Cd Length: 312 Bit Score: 297.87 E-value: 7.36e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 288 IAQRVAAGLSTTAATGGLIG---SVVALAISPLSFLNVADKFERAKQLEQYSERFKKFGYEGDSLLASFYRETGAIEAAL 364
Cdd:pfam02382 1 LAQRAAAGLATTGAVAVLILgitASLALAISPLEWAAFAQKFDYADDLDKLAQEFSDFGYEGDGLLAELLRGKGTIEASF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 365 TTINSVLSAASAGVGAAATGSLVGAPVAALVSAITGIISGILDASKQAIFERVATKLANKIDEWEKKhGKNYFENGYDAR 444
Cdd:pfam02382 81 YAISTALGVVSGGVSAAAAASGVGAPIALLVAGITGGISGILEASKQAMLEKVANRYAEKIRAKNNG-VQAYFENSFDAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 445 HSAFLEDTFELLSQYNKEYSVERVVAITQQRWDVNIGELAGITRKGSDTKSGKAYVDFFEEGKLLEKEPDRFDKKVFDPL 524
Cdd:pfam02382 160 HEALLEDNTKFLAELIKELNADRVIALGQQQWDANDGELAGISKLGGELKSGKAYVDAFEEGAKLEAGSWNTENIQLDAA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18026877 525 EGKIDLSSIN--KTTLLKFVTPVFTAGEEIRERKQTGKYEYMTELFVKGKEKWVVTGvQSHNAIYDYTNLIQ 594
Cdd:pfam02382 240 TGVIDISNVNgaKTQALTFTTPLLAAGTETRSRVHTGKNEYITTLKINRLKGWTIKD-GGANSTFDLSKVVQ 310
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
715-845 |
2.16e-18 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 86.11 E-value: 2.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 715 SVEEIIGSNRKDKFFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGG 794
Cdd:COG2931 93 GGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAGNDTLYGGAGNDTLDGG 172
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 18026877 795 DGDDelqvfegqynVLLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDI 845
Cdd:COG2931 173 AGND----------TLTGGAGNDTLTGGAGNDTLDGGGGDDTLGGGGGDDG 213
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
726-895 |
5.46e-16 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 78.79 E-value: 5.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 726 DKFFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDELQVFEG 805
Cdd:COG2931 77 DGGGGGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDTLYGGAG 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 806 QyNVLLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDIYRYSKEYGRHIIIEKGGDDDTLLLSDLSFKDVGFIRIGDD 885
Cdd:COG2931 157 N-DTLYGGAGNDTLDGGAGNDTLTGGAGNDTLTGGAGNDTLDGGGGDDTLGGGGGDDGLDGGDGDDGLGGGGGDDTLGGG 235
|
170
....*....|
gi 18026877 886 LLVNKRIGGT 895
Cdd:COG2931 236 GGGDGGGGGG 245
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
728-845 |
4.00e-10 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 61.46 E-value: 4.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 728 FFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDelqvfegqy 807
Cdd:COG2931 61 GGGGGGLDGGGGGGGGDGGGGGGGDDTDGGGDGGDGGGGGTGDDTGDGGGGNDTLTGGDGNDTLTGGAGDD--------- 131
|
90 100 110
....*....|....*....|....*....|....*...
gi 18026877 808 nVLLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDI 845
Cdd:COG2931 132 -TLYGGAGNDTLTGGAGNDTLYGGAGNDTLYGGAGNDT 168
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
747-782 |
1.19e-09 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 54.37 E-value: 1.19e-09
10 20 30
....*....|....*....|....*....|....*.
gi 18026877 747 YGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRL 782
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
756-791 |
2.85e-09 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 53.21 E-value: 2.85e-09
10 20 30
....*....|....*....|....*....|....*.
gi 18026877 756 YGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFL 791
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
765-800 |
2.40e-08 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 50.51 E-value: 2.40e-08
10 20 30
....*....|....*....|....*....|....*.
gi 18026877 765 HGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDEL 800
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| Peptidase_M10_C |
pfam08548 |
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ... |
783-849 |
5.07e-08 |
|
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.
Pssm-ID: 430067 [Multi-domain] Cd Length: 222 Bit Score: 54.69 E-value: 5.07e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18026877 783 IGGKGNNFLNGGDGDdelqvfegqyNVLLGGAGNDILYGsdgtnlfdgGVGNDKIYGGLGKDIYRYS 849
Cdd:pfam08548 85 IGGSGNDVLIGNDAD----------NILKGGAGNDILYG---------GGGADQLWGGAGNDIFVYA 132
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
738-773 |
1.24e-07 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 48.59 E-value: 1.24e-07
10 20 30
....*....|....*....|....*....|....*.
gi 18026877 738 HGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHL 773
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| Peptidase_M10_C |
pfam08548 |
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ... |
739-780 |
2.63e-07 |
|
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.
Pssm-ID: 430067 [Multi-domain] Cd Length: 222 Bit Score: 52.76 E-value: 2.63e-07
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 18026877 739 GAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGND 780
Cdd:pfam08548 86 GGSGNDVLIGNDADNILKGGAGNDILYGGGGADQLWGGAGND 127
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
730-845 |
1.74e-06 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 50.67 E-value: 1.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 730 GSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDELQVFEGqYNV 809
Cdd:COG2931 36 GGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGGGGGGDDTDGGGDGGDGGGGGTGDDTGDGGGG-NDT 114
|
90 100 110
....*....|....*....|....*....|....*.
gi 18026877 810 LLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDI 845
Cdd:COG2931 115 LTGGDGNDTLTGGAGDDTLYGGAGNDTLTGGAGNDT 150
|
|
| Peptidase_M10_C |
pfam08548 |
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ... |
736-800 |
1.87e-06 |
|
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.
Pssm-ID: 430067 [Multi-domain] Cd Length: 222 Bit Score: 50.06 E-value: 1.87e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18026877 736 IFHGAKGDDEIyGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDEL 800
Cdd:pfam08548 75 IAHGVTIENAI-GGSGNDVLIGNDADNILKGGAGNDILYGGGGADQLWGGAGNDIFVYASAKDSL 138
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
729-764 |
1.19e-05 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 42.81 E-value: 1.19e-05
10 20 30
....*....|....*....|....*....|....*.
gi 18026877 729 FGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVI 764
Cdd:pfam00353 1 YGGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
812-845 |
1.55e-05 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 42.81 E-value: 1.55e-05
10 20 30
....*....|....*....|....*....|....
gi 18026877 812 GGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDI 845
Cdd:pfam00353 2 GGDGNDTLVGGAGNDTIYGGAGNDTLDGGAGNDT 35
|
|
| COG2931 |
COG2931 |
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and ... |
728-845 |
6.97e-05 |
|
Ca2+-binding protein, RTX toxin-related [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442175 [Multi-domain] Cd Length: 252 Bit Score: 45.67 E-value: 6.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 728 FFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDELQVFEGqY 807
Cdd:COG2931 25 GGGGGGGGGGGGGGGGGGGGGGGGGDGGGGGGGGGGGGGGGGLDGGGGGGGGDGGGGGGGDDTDGGGDGGDGGGGGTG-D 103
|
90 100 110
....*....|....*....|....*....|....*...
gi 18026877 808 NVLLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDI 845
Cdd:COG2931 104 DTGDGGGGNDTLTGGDGNDTLTGGAGDDTLYGGAGNDT 141
|
|
| RTX_C |
pfam08339 |
RTX C-terminal domain; This family describes the C-terminal region of various bacterial ... |
874-987 |
1.60e-04 |
|
RTX C-terminal domain; This family describes the C-terminal region of various bacterial haemolysins and leukotoxins, which belong to the RTX family of toxins. These are produced by various Gram negative bacteria, such as E. coli and Actinobacillus pleuropneumoniae. RTX toxins may interact with lipopolysaccharide (LPS) to functionally impair and eventually kill leukocytes. This region is found in association with the RTX N-terminal domain (pfam02382) and multiple hemolysin-type calcium-binding repeats (pfam00353).
Pssm-ID: 429930 Cd Length: 131 Bit Score: 42.58 E-value: 1.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 874 FKDVGFIRIGDDLLVNKriggtlyyheDYNGNALTIKDWFKEGK------EGQNNKIEKIVDKDGAYVLSQYLTELtapg 947
Cdd:pfam08339 7 LSDLTFERVGNGLIIKK----------NDDSGSITFKNWFAALSrpnyhaSGTDDKIEEIIGKNGRYITSEQVDKL---- 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 18026877 948 rginyfngLEEKlyyGEGYNALPQLRK----------------DIEQIISSTGAFT 987
Cdd:pfam08339 73 --------LNNK---QSGKITSSQLQQlaqnksnminstdvanSLNKLISSMSGFG 117
|
|
| HemolysinCabind |
pfam00353 |
RTX calcium-binding nonapeptide repeat (4 copies); |
793-837 |
2.49e-04 |
|
RTX calcium-binding nonapeptide repeat (4 copies);
Pssm-ID: 459777 [Multi-domain] Cd Length: 36 Bit Score: 39.34 E-value: 2.49e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 18026877 793 GGDGDDelqvfegqynVLLGGAGNDILYGSDGTNLFDGGVGNDKI 837
Cdd:pfam00353 2 GGDGND----------TLVGGAGNDTIYGGAGNDTLDGGAGNDTL 36
|
|
| COG5412 |
COG5412 |
Phage-related protein [Mobilome: prophages, transposons]; |
10-414 |
1.08e-03 |
|
Phage-related protein [Mobilome: prophages, transposons];
Pssm-ID: 444167 [Multi-domain] Cd Length: 704 Bit Score: 43.15 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 10 KGLIDSLNQHTKSAAKSGAGALKNGLGQVKQAGQKLILYIPKDYQASTGSSLNDLVKAAEALGIEVHRSEKNGTALAKEL 89
Cdd:COG5412 70 ATLAAALGATVAGASLLLAAGGARAKGSAAAAAALGAVAAAAKVLNGALAAAGAALAATQALAAAATGAKGEANAAAKAG 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 90 FG---TTEKLLGFSERGIALFAPQFDKLLNKNQKLSKSLGGSS---EALGQRLNKTQTALSALQSFLGTAIAGMDLDSLL 163
Cdd:COG5412 150 GAaalASAGLAAAGAAAAASALAAAGAIAKAILSASKLSGQALagqSAAAGGALEAAAAAAAGAAAAGAAAAAATAASAL 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 164 RRRRNGEDVSGSELAKAGVDLAAQLVDNIASATGTVDAFAEQLGKLGNALSNTRLSGLASKLNNLPDLSLAGPGFDAVSG 243
Cdd:COG5412 230 LALAALQGLAAGAATGAAAGAAGAAGLGAAGAGAGQAAALLGLVAGAEASGGTAGGAVAGLAAGLAAAAGASANLGAAAA 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 244 ILSVVSASFILSNkDADAGTKAAAGIEISTKILGNIGKAVSQYIIAQRVAAGLSTTAATGGL---IGSVVALAISPLSFL 320
Cdd:COG5412 310 ASFGASLAASAGV-DTAAAALAAAEAIADGSLVAGLGSAGTVLSTLSGAVGGLEGAIGQLGAaggLGSALGGLTGPIGIV 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18026877 321 --NVADKFERAKQLEQYSERFKKF--GYEGDSLLASfyretgAIEAALTTINSVlsaasagvgaaatgslvgapVAALVS 396
Cdd:COG5412 389 iaAIAALIAAFVALWKNSETFRNLvqGVWELNAIKT------AIEGVVSAIVTF--------------------ISALWE 442
|
410
....*....|....*...
gi 18026877 397 AITGIISGILDASKQAIF 414
Cdd:COG5412 443 AIKALLTAIGGALPQLIA 460
|
|
| Peptidase_M10_C |
pfam08548 |
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix ... |
716-774 |
8.43e-03 |
|
Peptidase M10 serralysin C terminal; Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.
Pssm-ID: 430067 [Multi-domain] Cd Length: 222 Bit Score: 38.89 E-value: 8.43e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 18026877 716 VEEIIGSNRKDKFFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLV 774
Cdd:pfam08548 81 IENAIGGSGNDVLIGNDADNILKGGAGNDILYGGGGADQLWGGAGNDIFVYASAKDSLT 139
|
|
| |
