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Conserved domains on  [gi|19918718|gb|AAM07909|]
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multiple resistance/pH regulation related protein C (Na+/H+ antiporter) [Methanosarcina acetivorans C2A]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-141 4.82e-67

putative monovalent cation/H+ antiporter subunit C; Reviewed


:

Pssm-ID: 237162  Cd Length: 140  Bit Score: 199.23  E-value: 4.82e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    1 MNNFFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFtEGTLVPILEHeQALEGLGQGLIYNDNLTS 80
Cdd:PRK12661   1 MNNFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVF-EGTKVPIITE-QGHEGSGSGIIYNDNLTS 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19918718   81 GILGPITTN-PYTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:PRK12661  79 GILAPIVTNgPETEFVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIRELRRLRG 140
 
Name Accession Description Interval E-value
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-141 4.82e-67

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 199.23  E-value: 4.82e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    1 MNNFFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFtEGTLVPILEHeQALEGLGQGLIYNDNLTS 80
Cdd:PRK12661   1 MNNFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVF-EGTKVPIITE-QGHEGSGSGIIYNDNLTS 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19918718   81 GILGPITTN-PYTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:PRK12661  79 GILAPIVTNgPETEFVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIRELRRLRG 140
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
3-141 5.15e-36

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 119.84  E-value: 5.15e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718   3 NFFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFTEGTlVPILEHEQALEglgqgliyndnltsgi 82
Cdd:COG1006   2 ELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGA-PPILGEGPPAA---------------- 64

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 19918718  83 lgpittnpytEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:COG1006  65 ----------PYADPLPQALVLTAIVIGFAVTAFLLALAYRIYQLYGTDDVDELREDER 113
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-141 7.17e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 65.28  E-value: 7.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718     5 FLELTIALLFGIGTFLVL-RRDMMKVIIGFGIISHAINLYIVGSGVFTegtlvpileheqaleglgqgliyndnltsgil 83
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLT-------------------------------- 48

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 19918718    84 gpittnpytefVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:pfam00420  49 -----------ADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-141 4.82e-67

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 199.23  E-value: 4.82e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    1 MNNFFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFtEGTLVPILEHeQALEGLGQGLIYNDNLTS 80
Cdd:PRK12661   1 MNNFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVF-EGTKVPIITE-QGHEGSGSGIIYNDNLTS 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19918718   81 GILGPITTN-PYTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:PRK12661  79 GILAPIVTNgPETEFVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIRELRRLRG 140
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
3-141 5.15e-36

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 119.84  E-value: 5.15e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718   3 NFFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFTEGTlVPILEHEQALEglgqgliyndnltsgi 82
Cdd:COG1006   2 ELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGA-PPILGEGPPAA---------------- 64

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 19918718  83 lgpittnpytEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:COG1006  65 ----------PYADPLPQALVLTAIVIGFAVTAFLLALAYRIYQLYGTDDVDELREDER 113
PRK07375 PRK07375
Na+/H+ antiporter subunit C;
5-140 1.99e-21

Na+/H+ antiporter subunit C;


Pssm-ID: 236004  Cd Length: 112  Bit Score: 82.63  E-value: 1.99e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    5 FLELTIALLFGIGTF-LVLRRDMMKVIIGFGIISHAINLYIVGSGVfTEGTLVPILeheqaleglgqgliyndnltsgil 83
Cdd:PRK07375   4 MIYALAIALLVIGLYgLIFKRNLLKKIIGLDVFQTGVNLFYIAIGY-RSGGGVPIL------------------------ 58

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 19918718   84 gpiTTNPYTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLR 140
Cdd:PRK07375  59 ---SPSGFTTYADPLPQALVLTAIVIGFATTAVMLALIVKLYKDYGTLSESEIEKED 112
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
 9-137 1.12e-19

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 181497  Cd Length: 113  Bit Score: 78.07  E-value: 1.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    9 TIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFTEGTlVPILEHEQaleglgqgliyndnltsgilgpitt 88
Cdd:PRK08600   8 VIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTMGGLKKGA-VPILGEGV------------------------- 61

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 19918718   89 npyTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELR 137
Cdd:PRK08600  62 ---TSYVDPLPQALILTAIVISFGVTAFFLVLAYRTYKELGTDNVEQMR 107
PRK12659 PRK12659
Na+/H+ antiporter subunit C;
4-137 8.91e-18

Na+/H+ antiporter subunit C;


Pssm-ID: 183659  Cd Length: 117  Bit Score: 73.54  E-value: 8.91e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    4 FFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFTEGT--LVPileheqaleglgqgliyndnltSG 81
Cdd:PRK12659   3 FLLAIVVGGLYAAGIYMMLRRSIVKLVIGLILLGNAANLLIFTVGRLTRGAppLVP----------------------EG 60

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 19918718   82 ILGPITTnpyteFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELR 137
Cdd:PRK12659  61 ATAPAGP-----VADPLPQALILTAIVIGFGVQAFAIVLIKRAYQVVGTDDLDEMK 111
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
 3-137 1.39e-17

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 183660  Cd Length: 114  Bit Score: 72.85  E-value: 1.39e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    3 NFFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFTEGTLVPILEHEQaleglgqgliyndnltsgi 82
Cdd:PRK12660   2 NLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYGSSRSEPLITGGN------------------- 62

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 19918718   83 lgpittnpyTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELR 137
Cdd:PRK12660  63 ---------QLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLR 108
PRK09094 PRK09094
putative monovalent cation/H+ antiporter subunit C; Reviewed
 6-135 7.52e-17

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236377  Cd Length: 114  Bit Score: 71.06  E-value: 7.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    6 LELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGvftegtlvpileheqaleglgqgliyndNLTSG---I 82
Cdd:PRK09094   5 LALAIGVLTASGVWLLLRPRTFQVILGLSLLSYAVNLFIFAMG----------------------------RLRVGappV 56

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 19918718   83 LGPITTNPYTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGT--VDVQE 135
Cdd:PRK09094  57 LQPGVPVDLANYTDPLPQALVLTAIVIGFAMTALFLVVALASRGLTGTdhVDGRE 111
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-141 7.17e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 65.28  E-value: 7.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718     5 FLELTIALLFGIGTFLVL-RRDMMKVIIGFGIISHAINLYIVGSGVFTegtlvpileheqaleglgqgliyndnltsgil 83
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLT-------------------------------- 48

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 19918718    84 gpittnpytefVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:pfam00420  49 -----------ADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
PRK12658 PRK12658
Na+/H+ antiporter subunit C;
6-138 7.60e-15

Na+/H+ antiporter subunit C;


Pssm-ID: 183658  Cd Length: 125  Bit Score: 66.24  E-value: 7.60e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    6 LELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVFTEGtlVPILEHEQALeglgqgliyndnltsgILGP 85
Cdd:PRK12658   5 FAILVGVFFAAAIYLMLSRHIIRILFGLALLGNAVNLLIFTAGRLTRE--VPPLIPAGAD----------------VLAE 66

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 19918718   86 ITTNPytefvdpLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRR 138
Cdd:PRK12658  67 GAANP-------LPQALILTAIVIGFGLLAFLLVLAYRAYQDLGTDDTDEMRV 112
PRK07946 PRK07946
putative monovalent cation/H+ antiporter subunit C; Reviewed
 3-123 1.01e-14

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236136  Cd Length: 163  Bit Score: 66.61  E-value: 1.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    3 NFFLELTIALLFGIGTFLVLRRDMMKVIIGFGIISHAINLYIVGSGVftegtlvpileheqaleglgqgliyndnlTSG- 81
Cdd:PRK07946   4 NLGLLVAIGVLTSAGVYLLLERSLTRMLLGLLLIGNGVNLLILTAGG-----------------------------PAGn 54

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 19918718   82 --ILGPiTTNPYTEFVDPLVQALVLTAIVIGLATTAFVLTLCYR 123
Cdd:PRK07946  55 ppILGR-TSEYGETMADPLAQAMILTAIVITMGITAFVLALAYR 97
PRK08389 PRK08389
putative monovalent cation/H+ antiporter subunit C; Reviewed
 20-141 1.29e-13

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236258  Cd Length: 114  Bit Score: 62.83  E-value: 1.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718   20 LVLRRDMMKVIIGFGIISHAINLYIVGSGvFTEGTLVPILEHEqaleglgqgliyndnltsgilgpITTNPYtefVDPLV 99
Cdd:PRK08389  20 VLVKKNLLKIIIGLDIMETGVNLLLISIG-YVSGRSAPILSEG-----------------------ITPSNY---VDPIP 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 19918718  100 QALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLRE 141
Cdd:PRK08389  73 QALVLTAIVIGVSTTALALSVAIKLYEKYGTLNVEEIRRLRG 114
PRK08388 PRK08388
putative monovalent cation/H+ antiporter subunit C; Reviewed
 5-140 4.53e-11

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236257  Cd Length: 119  Bit Score: 56.06  E-value: 4.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19918718    5 FLELTIALLFGIGTFLVlRRDMMKVIIGFGIISHAINLYIVGSGVFTEGTLVPILEHEQALEGLGqgliyndnltsgilg 84
Cdd:PRK08388   6 FITAFLMIALGIYAFLY-KRNLIKLILALDLIDSGIHLLLISLGYRMENGLPPTAPIYTGYETLK--------------- 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 19918718   85 pittnpyTEFVDPLVQALVLTAIVIGLATTAFVLTLCYRVNEEYGTVDVQELRRLR 140
Cdd:PRK08388  70 -------SPMVGPIPQALVLTSIVIGVCVLSLAMALTINAYRHYGTLDVTKLRRLR 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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