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Conserved domains on  [gi|20152843|gb|AAM13391|]
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GLI1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 562-1081 1.51e-08

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.18  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   878 RPCLDFDSPTHSTGQLKAQlvcnyvqsqqellweggGREDAPAQePSYQSPKFLGDSQVSPSR---AKAPVNTYGPGF-- 952
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----------------PRPQPPLA-PTTDPAGAGEPSGAVPQPwlgALVPGRVAVPRFrv 2979

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   953 GPNLPNHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQ 1032
Cdd:PHA03247 2980 PQPAPSREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTE 3035

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 20152843  1033 VCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3036 DSDADSLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC super family cl24666
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


The actual alignment was detected with superfamily member pfam16159:

Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 20152843    237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 297-387 5.33e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 20152843  377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 562-1081 1.51e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.18  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   878 RPCLDFDSPTHSTGQLKAQlvcnyvqsqqellweggGREDAPAQePSYQSPKFLGDSQVSPSR---AKAPVNTYGPGF-- 952
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----------------PRPQPPLA-PTTDPAGAGEPSGAVPQPwlgALVPGRVAVPRFrv 2979

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   953 GPNLPNHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQ 1032
Cdd:PHA03247 2980 PQPAPSREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTE 3035

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 20152843  1033 VCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3036 DSDADSLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 20152843    237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 297-387 5.33e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 20152843  377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
317-344 2.68e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.68e-05
                           10        20
                   ....*....|....*....|....*...
gi 20152843    317 NLKTHLRSHTGEKPYMCEHegCSKAFSN 344
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
196-433 2.31e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  196 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 268
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  269 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 339
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  340 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 398
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 20152843  399 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 433
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 562-1081 1.51e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.18  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   562 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 638
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   639 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 718
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   719 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 797
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   798 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 877
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   878 RPCLDFDSPTHSTGQLKAQlvcnyvqsqqellweggGREDAPAQePSYQSPKFLGDSQVSPSR---AKAPVNTYGPGF-- 952
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----------------PRPQPPLA-PTTDPAGAGEPSGAVPQPwlgALVPGRVAVPRFrv 2979

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   953 GPNLPNHKSGSYPTPSPCHenfvvgaNRASHRAAAPPRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQ 1032
Cdd:PHA03247 2980 PQPAPSREAPASSTPPLTG-------HSLSRVSSWASSLALHEETDPPPVSLKQT-----------------LWPPDDTE 3035

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 20152843  1033 VCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 1081
Cdd:PHA03247 3036 DSDADSLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 237-265 2.59e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.59e-06
                           10        20
                   ....*....|....*....|....*....
gi 20152843    237 CRWDGCSQEFDSQEQLVHHINSEHIHGER 265
Cdd:pfam16159    7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 297-387 5.33e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 5.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  297 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 376
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 20152843  377 SSLRKHVKTVH 387
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
317-344 2.68e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.68e-05
                           10        20
                   ....*....|....*....|....*...
gi 20152843    317 NLKTHLRSHTGEKPYMCEHegCSKAFSN 344
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 725-877 3.10e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 48.54  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   725 PPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGP---PTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKAlgGTYS 801
Cdd:PRK10263  339 PVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPviaPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAA--EQPA 416

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 20152843   802 QCPRLEHYGQVQVKPEQGCPVGSDSTGLAPcLNAHPSEGPPHPQPLF---SHYPQPSPPQYLQSGPYTQPPPDYLPSEP 877
Cdd:PRK10263  417 QQPYYAPAPEQPAQQPYYAPAPEQPVAGNA-WQAEEQQSTFAPQSTYqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEP 494
zf-H2C2_2 pfam13465
Zinc-finger double domain;
287-314 3.23e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.59  E-value: 3.23e-05
                           10        20
                   ....*....|....*....|....*...
gi 20152843    287 MLVVHMRRHTGEKPHKCTFegCRKSYSR 314
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
299-379 3.55e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.30  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  299 KPHKCtfEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNaSDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSS 378
Cdd:COG5048   32 RPDSC--PNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSR-PLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108


                 .
gi 20152843  379 L 379
Cdd:COG5048  109 S 109
PHA03247 PHA03247
large tegument protein UL36; Provisional
 534-886 4.10e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 4.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   534 GPPVSLERRSSSSSSISSAYTVSRR-------------SSLASPFPPGSPPENGASSLPGLMPaqhylLRARYASARGGG 600
Cdd:PHA03247 2658 PGRVSRPRRARRLGRAAQASSPPQRprrraarptvgslTSLADPPPPPPTPEPAPHALVSATP-----LPPGPAAARQAS 2732

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   601 TSPTAAssldrigglPMPPwrsrAEYPGYNPNAGVTRRASDPAQAA-DRPAPARVqrfkslgcvhtPPTVAGGGQNFDPY 679
Cdd:PHA03247 2733 PALPAA---------PAPP----AVPAGPATPGGPARPARPPTTAGpPAPAPPAA-----------PAAGPPRRLTRPAV 2788

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   680 LPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPymdfPPTdtlgygGPEGAAAEPYGARGPGSLPLG----P 755
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP----PPT------SAQPTAPPPPPGPPPPSLPLGgsvaP 2858

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   756 GPPTNYGPnpcPQQASYPDPTQetwgefPSHSGLYPGPKalggtysqcPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNA 835
Cdd:PHA03247 2859 GGDVRRRP---PSRSPAAKPAA------PARPPVRRLAR---------PAVSRSTESFALPPDQPERPPQPQAPPPPQPQ 2920

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 20152843   836 HPSEGPPHPQPLFSHYPQPSPPqyLQSGPYTQPPPDYLPSEPRPCLDFDSP 886
Cdd:PHA03247 2921 PQPPPPPQPQPPPPPPPRPQPP--LAPTTDPAGAGEPSGAVPQPWLGALVP 2969
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
291-347 4.64e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.92  E-value: 4.64e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 20152843  291 HMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 347
Cdd:COG5048   52 HIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108
PHA03247 PHA03247
large tegument protein UL36; Provisional
 402-870 5.19e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 5.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   402 PLPRaPSISTVEPKREREGGPiREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSL 481
Cdd:PHA03247 2573 PAPR-PSEPAVTSRARRPDAP-PQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPE 2650

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   482 DEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTV---SRR 558
Cdd:PHA03247 2651 RPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGpaaARQ 2730

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   559 SSLASPFPPGSPPENGASSLPG-----------LMPAQHYLLRARYASARGGGTSPTAASSLDRIGGLPMPPWRSRAEYP 627
Cdd:PHA03247 2731 ASPALPAAPAPPAVPAGPATPGgparparppttAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAA 2810

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   628 GYNPNAGVTRRAS---------DPAQAADRPAPARVQRFKSLG--------CVHTPPTVAGGGQNFDPYLP--TSVYSPQ 688
Cdd:PHA03247 2811 VLAPAAALPPAASpagplppptSAQPTAPPPPPGPPPPSLPLGgsvapggdVRRRPPSRSPAAKPAAPARPpvRRLARPA 2890

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   689 PPSITENAAMDARGLQEEP---------EVGTSMVGSGLNPYMDFPP---------TDTLGYGGPEGAAAEPY-GARGPG 749
Cdd:PHA03247 2891 VSRSTESFALPPDQPERPPqpqappppqPQPQPPPPPQPQPPPPPPPrpqpplaptTDPAGAGEPSGAVPQPWlGALVPG 2970

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   750 SLPL------GPGPPTNYGPNPCPQQASYPDPTQETWG-EFPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQgcPV 822
Cdd:PHA03247 2971 RVAVprfrvpQPAPSREAPASSTPPLTGHSLSRVSSWAsSLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSD--SE 3048

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 20152843   823 GSDSTGLAPclnahpseGPPHPQPLFSHYPQPSPPQY-LQSGPYTQ--PPP 870
Cdd:PHA03247 3049 RSDLEALDP--------LPPEPHDPFAHEPDPATPEAgARESPSSQfgPPP 3091
dnaA PRK14086
chromosomal replication initiator protein DnaA;
763-983 6.78e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 43.66  E-value: 6.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   763 PNPCPQQASYPDPTQETWGEFPSHSglYPGPKALggtysqcPRLEHYGQVQVKPEqgcpvgsdSTGLAPCLNAHPSEGPp 842
Cdd:PRK14086   96 APPPPHARRTSEPELPRPGRRPYEG--YGGPRAD-------DRPPGLPRQDQLPT--------ARPAYPAYQQRPEPGA- 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   843 HPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEP-RPCLDFDSPTHSTGQLKaqlvcnyvQSQQELLWEGGGREDAPAQ 921
Cdd:PRK14086  158 WPRAADDYGWQQQRLGFPPRAPYASPASYAPEQERdREPYDAGRPEYDQRRRD--------YDHPRPDWDRPRRDRTDRP 229

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 20152843   922 EPSYQSPKFLGDSQVSPSRAKAPVNTYGPGFGPNLPNHKSgSYPTPSPCH---------ENFVVGA-NRASH 983
Cdd:PRK14086  230 EPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPA-PAPGPGEPTarlnpkytfDTFVIGAsNRFAH 300
PHA03247 PHA03247
large tegument protein UL36; Provisional
 562-1039 9.77e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 9.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   562 ASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASsldrigglPMPPWRSRAEYPGYNPNAgvtrrASD 641
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSAR--------PRAPVDDRGDPRGPAPPS-----PLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   642 PAQAA-DRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSgLNP 720
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS-LTS 2697

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   721 YMDFPPtdtlgyggPEGAAAEPYGARGPGsLPLGPGPPTNYGPNPCPQQASYPDPTQETwGEFPSHSGLYPGPKALGGTY 800
Cdd:PHA03247 2698 LADPPP--------PPPTPEPAPHALVSA-TPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPARPPTTAGPP 2767

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   801 SQCPrlehyGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPC 880
Cdd:PHA03247 2768 APAP-----PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   881 LDFDSPTHSTgqlkaqlvCNYVQSQQELLWEGGGREDAPA-QEPSYQSPKFLGDSQVSPSRAKAPVNTYGPgfgPNLPNH 959
Cdd:PHA03247 2843 PGPPPPSLPL--------GGSVAPGGDVRRRPPSRSPAAKpAAPARPPVRRLARPAVSRSTESFALPPDQP---ERPPQP 2911

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   960 KSGSYPTPSPCHENfvvgANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLggGPALYPPPEGQVCNPLDS 1039
Cdd:PHA03247 2912 QAPPPPQPQPQPPP----PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL--VPGRVAVPRFRVPQPAPS 2985
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
520-652 1.95e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843   520 PSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGG 599
Cdd:PRK12323  365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 20152843   600 GTSPTAASSLdriggLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPA 652
Cdd:PRK12323  445 GGAPAPAPAP-----AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPA 492
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
196-433 2.31e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  196 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 268
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  269 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 339
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  340 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 398
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 20152843  399 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 433
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
275-382 2.39e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.61  E-value: 2.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20152843  275 CSRELRPFKAQYMLVVHMR--RHTGE--KPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAK 350
Cdd:COG5048  292 SKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNEP 371

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 20152843  351 HQ----NRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 382
Cdd:COG5048  372 PQslqqYKDLKNDKKSETLSNSCIRNFKRDSNLSLH 407
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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