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Conserved domains on  [gi|21957174|gb|AAM84067|]
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preprotein translocase [Yersinia pestis KIM10+]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 10012582)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

Gene Ontology:  GO:0065002
PubMed:  15546659

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 38-129 2.21e-43

preprotein translocase subunit SecE; Reviewed


:

Pssm-ID: 235587  Cd Length: 92  Bit Score: 137.26  E-value: 2.21e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21957174   38 NYYYREYSLPLRALAVVVIIAVAGAVALMTAKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLD 117
Cdd:PRK05740   1 NYYLREQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALILWGLD 80

                         90
                 ....*....|..
gi 21957174  118 GILVRLVSFITG 129
Cdd:PRK05740  81 SILVWLISFITG 92
 
Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 38-129 2.21e-43

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 235587  Cd Length: 92  Bit Score: 137.26  E-value: 2.21e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21957174   38 NYYYREYSLPLRALAVVVIIAVAGAVALMTAKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLD 117
Cdd:PRK05740   1 NYYLREQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALILWGLD 80

                         90
                 ....*....|..
gi 21957174  118 GILVRLVSFITG 129
Cdd:PRK05740  81 SILVWLISFITG 92
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 64-129 5.15e-22

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 82.57  E-value: 5.15e-22
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21957174  64 ALMTAKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFITG 129
Cdd:COG0690   3 KKKTGKGKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 74-128 8.29e-16

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 66.30  E-value: 8.29e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 21957174    74 VAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFIT 128
Cdd:pfam00584   1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 74-127 2.46e-12

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 57.61  E-value: 2.46e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 21957174    74 VAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFI 127
Cdd:TIGR00964   2 FKFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
 
Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 38-129 2.21e-43

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 235587  Cd Length: 92  Bit Score: 137.26  E-value: 2.21e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21957174   38 NYYYREYSLPLRALAVVVIIAVAGAVALMTAKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLD 117
Cdd:PRK05740   1 NYYLREQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALILWGLD 80

                         90
                 ....*....|..
gi 21957174  118 GILVRLVSFITG 129
Cdd:PRK05740  81 SILVWLISFITG 92
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 64-129 5.15e-22

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 82.57  E-value: 5.15e-22
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21957174  64 ALMTAKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFITG 129
Cdd:COG0690   3 KKKTGKGKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 74-128 8.29e-16

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 66.30  E-value: 8.29e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 21957174    74 VAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFIT 128
Cdd:pfam00584   1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 64-127 4.68e-13

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 59.55  E-value: 4.68e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21957174   64 ALMTAKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFI 127
Cdd:PRK07597   1 LPKMSKMKKLKKFFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLISLL 64
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 74-127 2.46e-12

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 57.61  E-value: 2.46e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 21957174    74 VAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFI 127
Cdd:TIGR00964   2 FKFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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