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Conserved domains on  [gi|28190704|gb|AAO33169|]
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alpha-conotoxin GIC precursor, partial [Conus geographus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Toxin_8 super family cl06417
Alpha conotoxin precursor; This family consists of several alpha conotoxin precursor proteins ...
1-37 1.51e-10

Alpha conotoxin precursor; This family consists of several alpha conotoxin precursor proteins from a number of Conus species. The alpha-conotoxins are small peptide neurotoxins from the venom of fish-hunting cone snails which block nicotinic acetylcholine receptors (nAChRs).


The actual alignment was detected with superfamily member pfam07365:

Pssm-ID: 191732  Cd Length: 50  Bit Score: 49.34  E-value: 1.51e-10
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 28190704    1 SDGRNDAA--KAFDLISSTVKKGCCSHPACAGNNQHICG 37
Cdd:pfam07365 12 SDGRNAAAndKASDLIALTVRDGCCSNPPCRVSNPELCG 50
 
Name Accession Description Interval E-value
Toxin_8 pfam07365
Alpha conotoxin precursor; This family consists of several alpha conotoxin precursor proteins ...
1-37 1.51e-10

Alpha conotoxin precursor; This family consists of several alpha conotoxin precursor proteins from a number of Conus species. The alpha-conotoxins are small peptide neurotoxins from the venom of fish-hunting cone snails which block nicotinic acetylcholine receptors (nAChRs).


Pssm-ID: 191732  Cd Length: 50  Bit Score: 49.34  E-value: 1.51e-10
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 28190704    1 SDGRNDAA--KAFDLISSTVKKGCCSHPACAGNNQHICG 37
Cdd:pfam07365 12 SDGRNAAAndKASDLIALTVRDGCCSNPPCRVSNPELCG 50
 
Name Accession Description Interval E-value
Toxin_8 pfam07365
Alpha conotoxin precursor; This family consists of several alpha conotoxin precursor proteins ...
1-37 1.51e-10

Alpha conotoxin precursor; This family consists of several alpha conotoxin precursor proteins from a number of Conus species. The alpha-conotoxins are small peptide neurotoxins from the venom of fish-hunting cone snails which block nicotinic acetylcholine receptors (nAChRs).


Pssm-ID: 191732  Cd Length: 50  Bit Score: 49.34  E-value: 1.51e-10
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 28190704    1 SDGRNDAA--KAFDLISSTVKKGCCSHPACAGNNQHICG 37
Cdd:pfam07365 12 SDGRNAAAndKASDLIALTVRDGCCSNPPCRVSNPELCG 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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