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Conserved domains on  [gi|58802451|gb|AAW82431|]
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flavin containing monooxygenase 2 [Homo sapiens]

Protein Classification

flavin-binding monooxygenase-like family protein( domain architecture ID 1000557)

flavin-binding monooxygenase-like family protein; such as flavin-containing monooxygenases (FMOs) that catalyze the monooxygenation of a variety of substrates

EC:  1.14.13.-
Gene Ontology:  GO:0004497

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FMO-like super family cl30939
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-472 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


The actual alignment was detected with superfamily member pfam00743:

Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 944.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451     2 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDdFPMPEDFPN 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSD-FPFPEDYPN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    82 FLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSF 161
Cdd:pfam00743  80 FMHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   162 PGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFR 241
Cdd:pfam00743 160 PGIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   242 SMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEE 321
Cdd:pfam00743 240 SFLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEE 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   322 NIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAHLDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLP 401
Cdd:pfam00743 320 DIDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLP 399

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 58802451   402 SERTMMMDIIKRNEKRIDLFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSY 472
Cdd:pfam00743 400 SQSEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPY 470
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-472 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 944.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451     2 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDdFPMPEDFPN 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSD-FPFPEDYPN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    82 FLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSF 161
Cdd:pfam00743  80 FMHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   162 PGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFR 241
Cdd:pfam00743 160 PGIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   242 SMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEE 321
Cdd:pfam00743 240 SFLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEE 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   322 NIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAHLDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLP 401
Cdd:pfam00743 320 DIDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLP 399

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 58802451   402 SERTMMMDIIKRNEKRIDLFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSY 472
Cdd:pfam00743 400 SQSEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPY 470
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-397 1.81e-89

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 278.67  E-value: 1.81e-89
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   5 VAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRfkenveDGRasiYQSVVTNTSKEMSCFSDdFPMPEDFPNFLH 84
Cdd:COG2072   9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWR------DNR---YPGLRLDTPSHLYSLPF-FPNWSDDPDFPT 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  85 NSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDfssSGQWKVVTqSNGKEQSAvfDAVMVCSGHHILPHIPlkSFPGM 164
Cdd:COG2072  79 GDEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTT-DDGETLTA--RFVVVATGPLSRPKIP--DIPGL 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451 165 ERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRisEDGYPWDSVFHTRFRSML 244
Cdd:COG2072 151 EDFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPR--PNYDPERGRPANYLGLEA 228

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451 245 RNVLPRTAVKWMIEQQMNRWFNHENYG-LEPQNKYIMKEPVLNDDVPSRLLCGAIK-VKSTVKELTETSAIFEDGTVEEn 322
Cdd:COG2072 229 PPALNRRDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVFADGTEHE- 307

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 58802451 323 IDVIIFATGYSFSFPFLEDSLVKVEN--NMVSLYKYIFPAHLDksTLACIGLIQPLG--SIFPTAELQARWVTRVFKGL 397
Cdd:COG2072 308 VDVIVWATGFRADLPWLAPLDVRGRDgrSGPRAYLGVVVPGFP--NLFFLGPNSPSGhsSLTLGAERQARYIARLIAHM 384
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 2-448 6.33e-49

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 173.89  E-value: 6.33e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    2 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDG-----------RASIYQSVVTNTSKEMSCFS 70
Cdd:PLN02172  10 SQHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESDplsldptrsivHSSVYESLRTNLPRECMGYR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   71 DdFPM----------PEDFPNflhNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRkcpdfSSSGQWKVVTQ-SNGKEQSA 139
Cdd:PLN02172  90 D-FPFvprfddesrdSRRYPS---HREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKnSGGFSKDE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  140 VFDAVMVCSGHHILPHIplKSFPGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFIStrhgt 219
Cdd:PLN02172 161 IFDAVVVCNGHYTEPNV--AHIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIA----- 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  220 wvmSRISEdgypwdsvfhtrfrsmlrnvlPRTAVKWMIEQQmNRWFNHEnyglepqnkyimkepvlnddvpsrllcgaik 299
Cdd:PLN02172 234 ---SRASE---------------------SDTYEKLPVPQN-NLWMHSE------------------------------- 257

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  300 vKSTVKEltETSAIFEDGTVEEnIDVIIFATGYSFSFPFLE-DSLVKVENNMVS-LYKYIFPAHLDKStLACIGLiQPLG 377
Cdd:PLN02172 258 -IDTAHE--DGSIVFKNGKVVY-ADTIVHCTGYKYHFPFLEtNGYMRIDENRVEpLYKHVFPPALAPG-LSFIGL-PAMG 331

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 58802451  378 SIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRiDLFG--ESQSQTLQTNYVDYLDELALEIGAKP 448
Cdd:PLN02172 332 IQFVMFEIQSKWVAAVLSGRVTLPSEDKMMEDINAWYASL-EALGipKRYTHKLGKIQSEYLNWIAEECGCPL 403
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-472 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 944.60  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451     2 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDdFPMPEDFPN 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSD-FPFPEDYPN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    82 FLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSF 161
Cdd:pfam00743  80 FMHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   162 PGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFR 241
Cdd:pfam00743 160 PGIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   242 SMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEE 321
Cdd:pfam00743 240 SFLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEE 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   322 NIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAHLDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLP 401
Cdd:pfam00743 320 DIDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLP 399

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 58802451   402 SERTMMMDIIKRNEKRIDLFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSY 472
Cdd:pfam00743 400 SQSEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPY 470
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-397 1.81e-89

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 278.67  E-value: 1.81e-89
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   5 VAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRfkenveDGRasiYQSVVTNTSKEMSCFSDdFPMPEDFPNFLH 84
Cdd:COG2072   9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWR------DNR---YPGLRLDTPSHLYSLPF-FPNWSDDPDFPT 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  85 NSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDfssSGQWKVVTqSNGKEQSAvfDAVMVCSGHHILPHIPlkSFPGM 164
Cdd:COG2072  79 GDEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTT-DDGETLTA--RFVVVATGPLSRPKIP--DIPGL 150

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451 165 ERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRisEDGYPWDSVFHTRFRSML 244
Cdd:COG2072 151 EDFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPR--PNYDPERGRPANYLGLEA 228

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451 245 RNVLPRTAVKWMIEQQMNRWFNHENYG-LEPQNKYIMKEPVLNDDVPSRLLCGAIK-VKSTVKELTETSAIFEDGTVEEn 322
Cdd:COG2072 229 PPALNRRDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVFADGTEHE- 307

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 58802451 323 IDVIIFATGYSFSFPFLEDSLVKVEN--NMVSLYKYIFPAHLDksTLACIGLIQPLG--SIFPTAELQARWVTRVFKGL 397
Cdd:COG2072 308 VDVIVWATGFRADLPWLAPLDVRGRDgrSGPRAYLGVVVPGFP--NLFFLGPNSPSGhsSLTLGAERQARYIARLIAHM 384
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 2-448 6.33e-49

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 173.89  E-value: 6.33e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    2 AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDG-----------RASIYQSVVTNTSKEMSCFS 70
Cdd:PLN02172  10 SQHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESDplsldptrsivHSSVYESLRTNLPRECMGYR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   71 DdFPM----------PEDFPNflhNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRkcpdfSSSGQWKVVTQ-SNGKEQSA 139
Cdd:PLN02172  90 D-FPFvprfddesrdSRRYPS---HREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKnSGGFSKDE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  140 VFDAVMVCSGHHILPHIplKSFPGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFIStrhgt 219
Cdd:PLN02172 161 IFDAVVVCNGHYTEPNV--AHIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIA----- 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  220 wvmSRISEdgypwdsvfhtrfrsmlrnvlPRTAVKWMIEQQmNRWFNHEnyglepqnkyimkepvlnddvpsrllcgaik 299
Cdd:PLN02172 234 ---SRASE---------------------SDTYEKLPVPQN-NLWMHSE------------------------------- 257

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  300 vKSTVKEltETSAIFEDGTVEEnIDVIIFATGYSFSFPFLE-DSLVKVENNMVS-LYKYIFPAHLDKStLACIGLiQPLG 377
Cdd:PLN02172 258 -IDTAHE--DGSIVFKNGKVVY-ADTIVHCTGYKYHFPFLEtNGYMRIDENRVEpLYKHVFPPALAPG-LSFIGL-PAMG 331

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 58802451  378 SIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRiDLFG--ESQSQTLQTNYVDYLDELALEIGAKP 448
Cdd:PLN02172 332 IQFVMFEIQSKWVAAVLSGRVTLPSEDKMMEDINAWYASL-EALGipKRYTHKLGKIQSEYLNWIAEECGCPL 403
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
89-354 3.87e-17

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 81.89  E-value: 3.87e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    89 LEYFRIFAKKFDLLkyIQFQTTVLSVRKcpdfssSGQWKVVTQSNGKEQSavfDAVMVCSGHHILPHIPLKSFPGMerfk 168
Cdd:pfam13738  78 AEYLRRVADHFELP--INLFEEVTSVKK------EDDGFVVTTSKGTYQA---RYVIIATGEFDFPNKLGVPELPK---- 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   169 gqyfHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWvmsrisedgypwdsvfhtrfrsmlrnvl 248
Cdd:pfam13738 143 ----HYSYVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGSEW---------------------------- 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   249 prtavkwmieqqmNRWFNHENYGLEPQNKYIMKEPVLNddvpsrllcGAIKV--KSTVKELTETSAI----FEDGTVEEN 322
Cdd:pfam13738 191 -------------EDRDSDPSYSLSPDTLNRLEELVKN---------GKIKAhfNAEVKEITEVDVSykvhTEDGRKVTS 248

                         250       260       270
                  ....*....|....*....|....*....|..
gi 58802451   323 IDVIIFATGYSFSFPFLEDSLVKVENNMVSLY 354
Cdd:pfam13738 249 NDDPILATGYHPDLSFLKKGLFELDEDGRPVL 280
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 79-334 2.95e-08

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 55.28  E-value: 2.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    79 FPNFLHNSKLL------EYFRIFAKKFD---------LLKYIQFQTTVLSVRkcPDFSSSGQWKVVTQSNGKEQSAVFDA 143
Cdd:pfam13434  71 FLNYLHEHGRLysfynlETFFPSRREFNdylqwaashLPNRLRFGQEVESVE--PDAERGEPLLRVRVRDADGEETTFLA 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   144 VMVCSGHHILPHIPlKSFPGMERFkgqyFHSRQY--KHPDGFEGKRILVIGMGNSGSDIAVEL--SKNAAQVfistrhgT 219
Cdd:pfam13434 149 RNLVLGTGGEPYIP-ECARGGERV----FHSSEYleRIDRLAAKKRIAVVGSGQSAAEIFRDLlrRGPAYEL-------T 216

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   220 WVMSRISEdgYPWDSV----------FHTRFRSmlrnvLPRTAvkwmiEQQMNRWFNHENY-GLEPQ--NK-----YIMK 281
Cdd:pfam13434 217 WVTRSPNF--FPLDDSpfvneifspeYVDYFYS-----LPEDT-----RRALLREQKGTNYdGIDPSliEEiyrllYEQR 284

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 58802451   282 epvLNDDVPSRLL-----CGAIKVKSTVKELTeTSAIFEDGTVEENIDVIIFATGYSF 334
Cdd:pfam13434 285 ---VDGDPRHRLLpnrevQSAERVGDGGVELT-LRDGEQGREETLETDVVVLATGYRR 338
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
2-256 1.71e-07

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 53.42  E-value: 1.71e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   2 AKKVAVIGAGVSG---LISLKCCVDEGLEPTCFERTEDIGGvwrfkenvedGRAsiYQ----SVVTNT-SKEMSCFSDDf 73
Cdd:COG4529   5 RKRIAIIGGGASGtalAIHLLRRAPEPLRITLFEPRPELGR----------GVA--YStdspEHLLNVpAGRMSAFPDD- 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  74 pmPEDFPNFLHNSKLLEYFRIFAKKF-----------DLLKYIQ-----------FQTTVLSVRKCpdfssSGQWKVVTQ 131
Cdd:COG4529  72 --PDHFLRWLRENGARAAPAIDPDAFvprrlfgeylrERLAEALarapagvrlrhIRAEVVDLERD-----DGGYRVTLA 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451 132 SNgkeQSAVFDAVMVCSGHHiLPHIPlksfPGMERFKGQYFHS----RQYKHPDgfEGKRILVIGMGNSGSDIAVELSKN 207
Cdd:COG4529 145 DG---ETLRADAVVLATGHP-PPAPP----PGLAAGSPRYIADpwppGALARIP--PDARVLIIGTGLTAIDVVLSLAAR 214

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|...
gi 58802451 208 --AAQVFISTRHGtwVMSRISEDGYPWDSVFHT--RFRSMLRNVLPRTAVKWM 256
Cdd:COG4529 215 ghRGPITALSRRG--LLPRAHPPGAPLPLKFLTpeALEELPLFFAARTARDLL 265
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
4-216 5.13e-07

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 51.27  E-value: 5.13e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451   4 KVAVIGAGVSGL---ISLKccvDEGLEPTCFERTEdIGGvwrfkenvedgrasiyQsvVTNTSKemscfSDDFPmpeDFP 80
Cdd:COG0492   2 DVVIIGAGPAGLtaaIYAA---RAGLKTLVIEGGE-PGG----------------Q--LATTKE-----IENYP---GFP 51

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451  81 NFLHNSKLLEYFRIFAKKFDllkyIQFQTT-VLSVRKcpdfssSGQWKVVTQSNGKEQSAvfDAVMVCSGhhiLPHIPLK 159
Cdd:COG0492  52 EGISGPELAERLREQAERFG----AEILLEeVTSVDK------DDGPFRVTTDDGTEYEA--KAVIIATG---AGPRKLG 116

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 58802451 160 sFPGMERFKGQ---YFhsrqyKHPDG--FEGKRILVIGMGNSGSDIAVELSKNAAQVFISTR 216
Cdd:COG0492 117 -LPGEEEFEGRgvsYC-----ATCDGffFRGKDVVVVGGGDSALEEALYLTKFASKVTLIHR 172
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
6-150 1.65e-04

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 41.88  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451     6 AVIGAGVSGLIS----LKCCVDEGLEPTCFERTED-IGGVWRfKENVEDGRasiyqsvvTNT-SKEMSCFSDDfpmPEDF 79
Cdd:pfam13454   1 AIVGGGPSGLALlerlLARAPKRPLEITLFDPSPPgAGGVYR-TDQSPEHL--------LNVpASRMSLFPDD---PPHF 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58802451    80 PNFLHNSKLLEYF-----RIFAKKFDLLKYIQFQ------------------TTVLSVRKCPDfsssGQWkvVTQSNGke 136
Cdd:pfam13454  69 LEWLRARGALDEApgldpDDFPPRALYGRYLRDRfeealarapagvtvrvhrARVTDLRPRGD----GYR--VLLADG-- 140

                         170
                  ....*....|....
gi 58802451   137 QSAVFDAVMVCSGH 150
Cdd:pfam13454 141 RTLAADAVVLATGH 154
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-66 3.63e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 35.97  E-value: 3.63e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 58802451     7 VIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGV---WRFKENVEDGRASIYQSVVTNTSKEM 66
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNaysYRVPGYVFDYGAHIFHGSDEPNVRDL 63
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 3-43 5.00e-03

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 39.38  E-value: 5.00e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 58802451    3 KKVAVIGAGVSGLislkCCVDE----GLEPTCFERTEDIGGVWRF 43
Cdd:PRK12810 144 KKVAVVGSGPAGL----AAADQlaraGHKVTVFERADRIGGLLRY 184
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 3-43 5.36e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 38.96  E-value: 5.36e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 58802451   3 KKVAVIGAGVSGLislkCC----VDEGLEPTCFERTEDIGGVWRF 43
Cdd:COG0493 122 KKVAVVGSGPAGL----AAayqlARAGHEVTVFEALDKPGGLLRY 162
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-39 9.57e-03

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 38.27  E-value: 9.57e-03
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 58802451   3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGG 39
Cdd:COG1232   2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGG 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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