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Conserved domains on  [gi|1149047919|gb|AAX37238|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Cecropis cucullata]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-343 1.51e-152

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 432.32  E-value: 1.51e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIM 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTISLLSLLGLFFYLRLAYCSTITLPPHTTNHMKQWHTHKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|...
gi 1149047919 321 TNTLIAISVVASTMLLPISPMIY 343
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMIL 343
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-343 1.51e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 432.32  E-value: 1.51e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIM 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTISLLSLLGLFFYLRLAYCSTITLPPHTTNHMKQWHTHKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|...
gi 1149047919 321 TNTLIAISVVASTMLLPISPMIY 343
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMIL 343
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.21e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 95.84  E-value: 1.21e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  23 SNHWIMAWAGLEINTLSILPLI-SKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDITQM-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  91 HPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIM-KLPPITLLFMT------SNSLNPTLLTCmAIMSTA 163
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSllylpsSPFIQQILLIL-AIISML 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 164 LGGWMGLNQTQIRKILAFSSIAHLGWMAIILS----FNPKLTMLNFYLYILMTSTIFL-----TLNTTKVLKLSTLMTTW 234
Cdd:pfam00361 160 LGSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLA 239

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1149047919 235 TKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQ 268
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-275 1.28e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 92.49  E-value: 1.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  14 LLGTTITITSNHWIMAWAGLEINTLSILPLIS-KSHHPRAIEAATKYFLTQATASTLVLF-SSMTNAWhTGQWDITQMTH 91
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  92 PIS------------CLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKL----PPITLLFMTSNSLNP---T 152
Cdd:COG1007   191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAAdwqL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 153 LLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTM--LNFYL--YILMTSTIFLTL-----NTTK 223
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVIlllsrKGGE 350

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1149047919 224 VLKLSTLMTTWTKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGL 275
Cdd:COG1007   351 AEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGL 402
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 8.39e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.84  E-value: 8.39e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  14 LLGTTITITSNHWIMAWAGLEINTLSILPLIS-KSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDITQMTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  93 ISCLILT------------SAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLP---PITLLFMT-----SNSLNPT 152
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYilfgfSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 153 LLTCmAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLN--FYL--YILMTSTIFLTLNTTKVLK-- 226
Cdd:TIGR01770 272 LAII-AFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKde 350

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1149047919 227 ----LSTLMTTWTKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGL 275
Cdd:TIGR01770 351 wieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-343 1.51e-152

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 432.32  E-value: 1.51e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIM 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTISLLSLLGLFFYLRLAYCSTITLPPHTTNHMKQWHTHKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|...
gi 1149047919 321 TNTLIAISVVASTMLLPISPMIY 343
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMIL 343
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-342 2.55e-129

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 373.37  E-value: 2.55e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSlNPTLLTCMAIM 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTISLLSLLGLFFYLRLAYCSTITLPPHTTNHMKQWHTHKP 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                         330       340
                  ....*....|....*....|...
gi 1149047919 321 TNTL-IAISVVASTMLLPISPMI 342
Cdd:MTH00135  320 QLTLpLAISTTATLMLLPLTPAI 342
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-342 1.53e-124

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 361.16  E-value: 1.53e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIM 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTISLLSLLGLFFYLRLAYCSTITLPPHTTNHMKQWHTHKP 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                         330       340
                  ....*....|....*....|..
gi 1149047919 321 TNTLIAISVVASTMLLPISPMI 342
Cdd:MTH00070  321 TNNLLSLTIILSLMLLPITPTI 342
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-344 6.90e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 324.11  E-value: 6.90e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIM 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTISLLSLLGLFFYLRLAYCSTITLPPhTTNHMK-QWH-TH 318
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKmKWQfEN 319

                         330       340
                  ....*....|....*....|....*.
gi 1149047919 319 KPTNTLIAISVVASTMLLPISPMIYI 344
Cdd:MTH00105  320 TKPMTLLPTLIILSTMLLPLTPMLSI 345
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-342 8.36e-94

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 283.01  E-value: 8.36e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIM 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTISLLSLLGLFFYLRLAYCSTITLPPHTTNHMKQWHTHKP 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                         330       340
                  ....*....|....*....|..
gi 1149047919 321 TNTLIAISVVASTMLLPISPMI 342
Cdd:MTH00200  321 SNLLVGLLLLLSILGLPLTPQL 342
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-267 2.10e-75

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 235.98  E-value: 2.10e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWH 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 TGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIM 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260
                  ....*....|....*....|....*..
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLII 267
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISL 267
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-270 6.50e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 169.62  E-value: 6.50e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   1 MN*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWh 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  81 tgqwdITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSlnpTLLTCMAIM 160
Cdd:MTH00160   81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINN---NFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 161 STALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPAL 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270
                  ....*....|....*....|....*....|
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLIIQEL 270
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLL 262
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-272 6.59e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 151.19  E-value: 6.59e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   5 AKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQW 84
Cdd:MTH00144    5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  85 DITqmthpiscLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTC-MAIMSTA 163
Cdd:MTH00144   85 FSM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCvISVLSAL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 164 LGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNtTKVLKLSTLMTTWTKAPALNAM 243
Cdd:MTH00144  157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLW-SGDSGSMKDLGSLKPSYKTGLS 235

                         250       260
                  ....*....|....*....|....*....
gi 1149047919 244 LLLALLSLAGLPPMTGFLPKWLIIQELTK 272
Cdd:MTH00144  236 IISLLLSLGGLPPFLGFCSKLLVLISSME 264
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 7-271 9.06e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 148.39  E-value: 9.06e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   7 LIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSmtnawhTGQWDI 86
Cdd:MTH00011    9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  87 TQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPTLLTCMAIMSTALGG 166
Cdd:MTH00011   83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 167 WMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPALNAMLLL 246
Cdd:MTH00011  163 LGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFI 242

                         250       260
                  ....*....|....*....|....*
gi 1149047919 247 ALLSLAGLPPMTGFLPKWLIIQELT 271
Cdd:MTH00011  243 MLLSLGGLPPFTGFMPKLMAIETLT 267
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-270 5.09e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 132.87  E-value: 5.09e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   8 IFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTgqwdit 87
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  88 qMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLfmTSNSLNPTLLTCMAIMSTALGGW 167
Cdd:MTH00197   76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGGI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 168 MGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYILMTSTIFLTLNTTKVLKLSTLMTTWTKAPALNAMLLLA 247
Cdd:MTH00197  153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                         250       260
                  ....*....|....*....|...
gi 1149047919 248 LLSLAGLPPMTGFLPKWLIIQEL 270
Cdd:MTH00197  233 FLSLGGLPPLSGFFLKWLILTSL 255
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-267 4.90e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 101.26  E-value: 4.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  13 LLLGTTITITSNHWIMAWAGLEINTLSILPLI-SKSHHPRAIEAATKYFLTQATASTLVLFS-------------SMTNA 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  79 WHTGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNptLLTCMA 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 159 IMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNP----KLTMLNFYLYILMTSTIF---LTLNTTK--VLKLST 229
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFsiiLALNVYKnlIIEFSG 239

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1149047919 230 LMttwTKAPALNAMLLLALLSLAGLPPMTGFLPKWLII 267
Cdd:MTH00196  240 LS---RRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.21e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 95.84  E-value: 1.21e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  23 SNHWIMAWAGLEINTLSILPLI-SKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDITQM-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  91 HPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIM-KLPPITLLFMT------SNSLNPTLLTCmAIMSTA 163
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSllylpsSPFIQQILLIL-AIISML 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 164 LGGWMGLNQTQIRKILAFSSIAHLGWMAIILS----FNPKLTMLNFYLYILMTSTIFL-----TLNTTKVLKLSTLMTTW 234
Cdd:pfam00361 160 LGSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLA 239

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1149047919 235 TKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQ 268
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-275 1.28e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 92.49  E-value: 1.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  14 LLGTTITITSNHWIMAWAGLEINTLSILPLIS-KSHHPRAIEAATKYFLTQATASTLVLF-SSMTNAWhTGQWDITQMTH 91
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  92 PIS------------CLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKL----PPITLLFMTSNSLNP---T 152
Cdd:COG1007   191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAAdwqL 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 153 LLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTM--LNFYL--YILMTSTIFLTL-----NTTK 223
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVIlllsrKGGE 350

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1149047919 224 VLKLSTLMTTWTKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGL 275
Cdd:COG1007   351 AEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGL 402
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-267 1.45e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 92.00  E-value: 1.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  13 LLLGTTITITSNHWIMAWAGLEINTLSILPLIS-KSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDI----T 87
Cdd:MTH00199  106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  88 QMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNpTLLTCmAIMSTALGGW 167
Cdd:MTH00199  186 ILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN-VVLIC-AVLSIIYGAI 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 168 MGLNQTQIRKILAFSSIAHLG---WMAIILSFNP-KLTMLNFYLYILMTSTIF---LTLNTTKVLkLSTLMTTWTKAPAL 240
Cdd:MTH00199  264 GALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFsiiLSLKLTKGL-IVEVSGLSRKNPVI 342

                         250       260
                  ....*....|....*....|....*..
gi 1149047919 241 NAMLLLALLSLAGLPPMTGFLPKWLII 267
Cdd:MTH00199  343 ALTLALTFLSIAGIPPLAGFLSKWLIL 369
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 8.39e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.84  E-value: 8.39e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  14 LLGTTITITSNHWIMAWAGLEINTLSILPLIS-KSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDITQMTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  93 ISCLILT------------SAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLP---PITLLFMT-----SNSLNPT 152
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYilfgfSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 153 LLTCmAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLN--FYL--YILMTSTIFLTLNTTKVLK-- 226
Cdd:TIGR01770 272 LAII-AFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlFYIfiYALMSLGAFGVLSLLRSYKde 350

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1149047919 227 ----LSTLMTTWTKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGL 275
Cdd:TIGR01770 351 wieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGL 403
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-210 1.74e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 77.21  E-value: 1.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  15 LGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAI---------EAATKYFLTQATASTLVLFSSMTNAWHTGQ-- 83
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  84 ------------WDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLLfmTSNSLNP 151
Cdd:MTH00198  279 mlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITS 356

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1149047919 152 TLLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYIL 210
Cdd:MTH00198  357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV 415
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-279 1.91e-15

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 76.78  E-value: 1.91e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  14 LLGTTITITSNHWIMAWAGLEINTLSILPLIS-KSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDITQMTHP 92
Cdd:PRK05777  113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  93 IS------------CLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKL----PPITLLFMTSNSLNPT---L 153
Cdd:PRK05777  193 LAdgsgnsllllfgLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqqV 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 154 LTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWM--AIILSFNPKLTMLNFYL--YILMT--STIFLTL------NT 221
Cdd:PRK05777  273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvGLAAGTAEGYSAVLFYLlaYLFMTlgAFGVISLlrrkggEA 352

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1149047919 222 TKVLKLSTLMTTwtkAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAA 279
Cdd:PRK05777  353 ESISDFAGLSKR---SPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLA 407
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-279 3.41e-15

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 75.95  E-value: 3.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  13 LLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDITQMTHP 92
Cdd:COG0651   116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAR 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  93 IS----------CLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIM-KLPP------ITLLFMTSNSLNP-TLL 154
Cdd:COG0651   196 LAeldpglllaaFALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtKVGVyailrvLTLLFGADPALFLgTLL 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 155 TCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYI----LMTSTIFLT----LNTTKVLK 226
Cdd:COG0651   276 LVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFLAagaiERATGTRD 355

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1149047919 227 LSTLMTTWTKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAA 279
Cdd:COG0651   356 LDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLA 408
ndhB CHL00049
NADH dehydrogenase subunit 2
 7-211 1.64e-11

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 65.03  E-value: 1.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   7 LIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHP-RAIEAATKYFLTQATASTLVL--FSSM--TNAWHT 81
Cdd:CHL00049  114 LLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFSWLygLSGGEI 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  82 GQWDI------TQMTHPISCLI----LTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPP-------ITLLFM 144
Cdd:CHL00049  194 ELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAAsalatriFDIPFY 273

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1149047919 145 TSNSLNPTLLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAI-ILSFNPKL---TMLNFYL-YILM 211
Cdd:CHL00049  274 FSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIgIIVGDSNDgyaSMITYMLfYIFM 345
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-198 2.65e-10

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 61.25  E-value: 2.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  49 HPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQW--DITQ-MTHPIS-------CLILTSAIAMKLGMVPFHFWFPEV 118
Cdd:COG1008   156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAElAAAPLPltaqlllFLAFFIAFAVKVPMFPFHTWLPDA 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 119 LQGAPLTTGLLLSTIM-KLP-------PITLLFMTSNSLNPTLLTcMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWM 190
Cdd:COG1008   236 HVEAPTAGSVLLAGVLlKMGgygllrfALPLFPEASAYFAPLLAA-LGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFV 314


                  ....*....
gi 1149047919 191 AI-ILSFNP 198
Cdd:COG1008   315 LLgIFALNP 323
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-192 1.45e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 58.91  E-value: 1.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  50 PRAIEAATKYFLTQATASTLVLF-SSMTNAWHTGQWDITQMTHP----------ISCLILTSAIAMKLGMVPFHFWFPEV 118
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSAIALAlitspslglaLALVFVIAGIAFKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 119 LQGAPLTTGLLLSTIMKLP----PITLLFMTSNSLNP---TLLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMA 191
Cdd:PRK02504  237 YEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316


                  .
gi 1149047919 192 I 192
Cdd:PRK02504  317 I 317
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-198 1.70e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 55.72  E-value: 1.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  50 PRAIEAATKYFLTQATASTLVLFSSMTNAW-HTGQWDITQ-MTHPISC-------LILTSAIAMKLGMVPFHFWFPEVLQ 120
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFlGGGTFDLLElLNLPLPFgvqtwlfLAFFIAFAVKVPLFPLHTWLPDAHV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 121 GAPLTTGLLLSTIM-KLPP-------ITLLFMTSNSLNPtLLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAI 192
Cdd:TIGR01972 232 EAPTAGSVILAGVLlKMGTygflrfnLPLFPDASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310


                  ....*..
gi 1149047919 193 -ILSFNP 198
Cdd:TIGR01972 311 gIFSFNE 317
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 8-192 6.30e-08

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 53.78  E-value: 6.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   8 IFTFSLLLgttiTITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFL------TQATASTLVLFSS----MTN 77
Cdd:PRK06458  116 LFLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANaatvMGD 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  78 AWHTGQW-DITQMTHPISCLILTSAIAM-------KLGMVPFHFWFPEVLQGAP-----LTTGLLLST----IMKLPPIT 140
Cdd:PRK06458  192 GEMAILWtELLKHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDAHSEAPspvsaLLSGVLLNValyaVLRYYILI 271

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1149047919 141 LLFMTSNSLNPtLLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAI 192
Cdd:PRK06458  272 DAAIGSDFPGR-LLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-190 2.37e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 52.41  E-value: 2.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  33 LEINTLSILPLIS-KSHHPRAIEAATKYFLTQATASTLVLFSSmtnAWHTGQWDITQM-------------THPISCLIL 98
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMaylavkmsenptvVAKIALALF 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  99 TSAIAMKLGMVPFHFWFPEVLQGAP--LTTGLLLSTIMKLPPITLLFMT--SNSLNPT----LLTCMAIMSTALGGWMGL 170
Cdd:PRK08376  227 IAGLAMKSGAVPVHMWLPDAYPAAPssISAMLLVIKQAGLYALARVLFSiyGPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                         170       180
                  ....*....|....*....|
gi 1149047919 171 NQTQIRKILAFSSIAHLGWM 190
Cdd:PRK08376  307 VQKDVKRLLAYHSVSQIGYM 326
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 9-192 2.01e-06

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 49.37  E-value: 2.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   9 FTFSLLLGT-TITITSNHWIMAWAGLEINTLSILPLISKSHHPRAIEAATKYFLTQATA------STLVLFSSMTNAWHT 81
Cdd:PRK08676  106 LGFNLLLSViTFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGT 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  82 GQWDITQMTHP----------ISCLILTSAIAMKLGMVPFHFWFPEVLQGAP-LTTGLLLSTIMKLPPITLLFMTS---- 146
Cdd:PRK08676  186 GTLNWTELAAHasllspsvlgASFLFIFIGFLAKSGLVPFHTWLPAAYAKAPsVVSALLSGTVLNIGIYGILRLSAllrq 265

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1149047919 147 NSLNPT---LLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAI 192
Cdd:PRK08676  266 SGAAEQfsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLL 314
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-197 5.18e-06

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 47.89  E-value: 5.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  50 PRAIEAATKYFLTQATASTLVLFSSMTNAWH----TGQWDITQ-MTHPISC-------LILTSAIAMKLGMVPFHFWFPE 117
Cdd:PRK05846  157 KNRIYAATKFFLYTLLGSLLMLVAIIYLVVVyynaTGTFDIADlLNLPLPPgvqywlfLAFFIAFAVKMPMFPLHTWLPD 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 118 VLQGAPLTTGLLLSTIM-KLPPITLL-FM------TSNSLNPTLLTcMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGW 189
Cdd:PRK05846  237 AHVQAPTAGSVLLAGILlKMGAYGLLrFSlplfpdASHEFAPIIIT-LGVIAIIYGALVALAQTDIKKLIAYSSISHMGF 315


                  ....*....
gi 1149047919 190 MAI-ILSFN 197
Cdd:PRK05846  316 VTLgIFAGN 324
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-282 6.94e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.57  E-value: 6.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  33 LEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFS-----SMTNAWHTGqwDITQMTHPISCL-----ILTSAI 102
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvgllyGVTGTLNMA--DLAGALAENPTVvtafgFVLLAL 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 103 AMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPI-----------TLLFMTSNSLNpTLLTCMAIMSTALGGWMGLN 171
Cdd:PRK08375  213 ALKAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAVyaliriyftvfGGDFRFALGLG-WLLAVLALLSMLVGSLAALG 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 172 QTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYI----LMTSTIFL-------TLNTTKVLKLSTLMTT--WTkap 238
Cdd:PRK08375  292 QDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLlhhaLMKGALFLaagaievTYGTRRLSELSGLGRRmpLT--- 368

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1149047919 239 alNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGLAPAATTI 282
Cdd:PRK08375  369 --AAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVL 410
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-267 1.24e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 46.65  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  33 LEINTLSILPLISKSHHPRAIEAATKYFLTQATASTLVLFS-----SMTNAWHTGqwDITQMTHP--------ISCLILT 99
Cdd:PRK12662  139 LEISSISSYVLVAMGRDKKALVAAFEYLIIGTIGATFYLIGigflyAITGTLNMG--DMFLIIQDlptnraiqIGVLFIM 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 100 SAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITL------------LFMTSNSLNpTLLTCMAIMSTALGGW 167
Cdd:PRK12662  217 VGLFIKAALFPFHKWLIQAYSEAPSFISVFFSGTSTKVMIYLiirivydvfkanFVFTTLPFN-NVFMILAALAIVFGSV 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 168 MGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLTMLNFYLYI----LMTSTIFLT-------LNTTKVLKLSTLmttWTK 236
Cdd:PRK12662  296 LAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIvnhsIVKSALFMVsgsisyhFGTTKLEDCLNL---WKS 372

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1149047919 237 APALNAMLLLALLSLAGLPPMTGFLPKWLII 267
Cdd:PRK12662  373 MPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-275 1.38e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 46.91  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   2 N*QAKLIFTFSLLLGTTITITSNHWIMAWAGLEINTLSILPLISKSHHpRAIEAATKYFLTQATASTLVLFSSMTNAWHT 81
Cdd:PRK08668   96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKT 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  82 GQWDIT-------QMTHPISCLI----LTSAIAMKLGMVPFHFWFPE-----------VLQGAPLTTG-----LLLSTIM 134
Cdd:PRK08668  175 GTFDFAdisqgliNDTSTGFALIvflfLLAFGVAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLGaygflLVLYVLP 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 135 --KLPPITLLFMTSNSLNPTLLTCMAImSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKLT----MLNFYLY 208
Cdd:PRK08668  255 gtKLFSEFGTYRGVPLFNYILAWLGNI-SIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGfaggLFHVFNH 333

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1149047919 209 ILMTSTIFLTLNT----TKVLKLSTLMTTWTKAPALNAMLLLALLSLAGLPPMTGFLPKWLIIQELTKQGL 275
Cdd:PRK08668  334 ALFKGLFFLIFAAviyrTGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGM 404
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 7-194 1.63e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 46.68  E-value: 1.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919   7 LIFTFSLLLgttiTITSNHWIMAWAGLEINTLSILPLISKSHH-PRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWD 85
Cdd:COG1009   118 LLFMAAMLG----LVLSDNLLLLFVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLN 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  86 ITQMTH------------PISCLILTSAIAmKLGMVPFHFWFPEVLQG-----APL------TTGLLLstIMKLPPITll 142
Cdd:COG1009   194 FSELLAaaptilssplltLILLLLLLGAFG-KSAQFPLHFWLPDAMEGptpvsALLhaatmvKAGVYL--LARLSPLF-- 268

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1149047919 143 fmtsnSLNPTLLTCMAI--MSTAL-GGWMGLNQTQIRKILAFSSIAHLGWMAIIL 194
Cdd:COG1009   269 -----ALSPVWLTVVAIigAITALfAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 295-340 4.18e-05

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 40.70  E-value: 4.18e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1149047919 295 RLAYCSTITLPPHTTNHMKQWHTHKPTNT-LIAISVVASTMLLPISP 340
Cdd:pfam06444   5 RLSYSTTLTLFPNTNNSKMKWRFNSTKNTlLLPTLTTLSILLLPLTP 51
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 101-194 1.21e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 43.76  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 101 AIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTI-MKLPPITLLFMT-------SNSLNPTLLTcMAIMSTALGGWMGLNQ 172
Cdd:MTH00226  239 AMAVKIPIFPFHIWLPKAHVEAPVAGSVLLAGIlLKLGGYGLVRLSwpilplgAQNLAPAVIA-MGIVGIVYGSFATCRQ 317

                          90       100
                  ....*....|....*....|..
gi 1149047919 173 TQIRKILAFSSIAHLGWMAIIL 194
Cdd:MTH00226  318 IDVKRLVAYSSVAHMGLVSITL 339
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-190 4.20e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.99  E-value: 4.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  55 AATKYFLTQATASTLVLFSSMTNAWHTGQWDI---TQMTH--PISCLILTSA-----IAMKLGMVPFHFWFPEVLQGAPL 124
Cdd:PRK06473  158 AATKFLLYTAISGILILVSFLGLVWLSGASSFdyePLRSHtlPLSTQLLLLApilvgFGIKIPLVPFHTWLPDAHVEAST 237

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1149047919 125 TTGLLLSTIM-KLPP-------ITLLFMTSNSLNPTLLTcMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWM 190
Cdd:PRK06473  238 PVSVLLAGVLlKLGTygllrfgVGLFPEAWVYLAPWLAT-WAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-197 6.11e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.56  E-value: 6.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  55 AATKYFLTQATASTLVLFSSMTNAWHTGQ--WDITQMTH---PISCLILTSA---IA--MKLGMVPFHFWFPE------- 117
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAksyPLALELLLYAgflIAfgVKLPIFPLHTWLPDahgeasa 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 118 ----VLQGAPLTTG---LLLSTIMKLPPITLLFmtsnslnPTLLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWM 190
Cdd:PRK12561  218 pvsmILAGVLLKMGgyaLIRFNVQMLPDAHVYF-------APALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFV 290


                  ....*...
gi 1149047919 191 AI-ILSFN 197
Cdd:PRK12561  291 LLgIAAFT 298
ND5 MTH00211
NADH dehydrogenase subunit 5; Provisional
 69-200 1.29e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214459 [Multi-domain]  Cd Length: 597  Bit Score: 40.71  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  69 LVLFSSMTNAWHTGQWDITQMTHPISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLL-----F 143
Cdd:MTH00211  181 MVWLLLNLNSWEISQLFILNLDLTLFLLGLLLAAMGKSAQFGFHPWLPSAMEGPTPVSALLHSSTMVVAGVFLLirlspL 260

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1149047919 144 MTSNSLNPTLLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWMAIILSFNPKL 200
Cdd:MTH00211  261 FQNNQLILGAVLLLGALTMLFGALCALTQNDIKKIVAFSTTSQLGLMMVTLGLNQPQ 317
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 101-188 2.72e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 39.28  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 101 AIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTI-MKLPPITLLFMT-------SNSLNPTLLTcMAIMSTALGGWMGLNQ 172
Cdd:MTH00204  218 SLAVKIPQIPFHIWLPQAHVEAPVAGSVILAGIlLKLGGYGFLRFSwplfpaaSEYFAPLIVM-LSVIAVIYGSLTTCRQ 296

                          90
                  ....*....|....*.
gi 1149047919 173 TQIRKILAFSSIAHLG 188
Cdd:MTH00204  297 VDFKRLIAYSSVAHMG 312
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-190 2.83e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 39.43  E-value: 2.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  48 HHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDITQMTHP--------------ISCLILTSAIAMKLGMVPFHF 113
Cdd:PRK12649  156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDselienikghplflITLILIFIGAAAKSAQGPFYI 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919 114 WFPEVLQGAPLTTGLLLSTIMKLPPITLLFMTSNSLNPT-----LLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLG 188
Cdd:PRK12649  236 WLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQLA 315


                  ..
gi 1149047919 189 WM 190
Cdd:PRK12649  316 YL 317
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
13-190 7.64e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 38.14  E-value: 7.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  13 LLLGTTITITSNHW---IMAWA--GLEINTLsilpLISKSHHPRAIEAATKYFLTQATASTLVLFSSMTNAWHTGQWDI- 86
Cdd:PRK08168  109 VLAAVHLLVLSDHLlvlIAAWAaiSLALHRL----LCFYPDRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLs 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149047919  87 -------TQMTHP---ISCLILTSAIAMKLGMVPFHFWFPEVLQGAPLTTGLLLSTIMKLPPITLL-FMTSNSLNP---T 152
Cdd:PRK08168  185 alwahlaAQGASPslqAAALLLVLAVILKTAQLPVHGWLIQVMEAPTPVSALLHAGVVNLGGFVLIrFAPLLEQAPparW 264

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1149047919 153 LLTCMAIMSTALGGWMGLNQTQIRKILAFSSIAHLGWM 190
Cdd:PRK08168  265 LLVLVGLATAVLAGLVMLTRISIKVRLAWSTVAQMGFM 302
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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