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Conserved domains on  [gi|70955192|gb|AAZ16223|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Barnardius zonarius]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.37e-144

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 412.29  E-value: 1.37e-144
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    1 MGPFTKLISTTSLTLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   81 TGQWDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSIT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  241 NTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 70955192  321 TNTLTPPITSLSILLLPLSPMILTTT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.37e-144

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 412.29  E-value: 1.37e-144
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    1 MGPFTKLISTTSLTLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   81 TGQWDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSIT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  241 NTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 70955192  321 TNTLTPPITSLSILLLPLSPMILTTT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-298 1.75e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 94.80  E-value: 1.75e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  23 SNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQL--------TYPP 93
Cdd:COG1007 121 ANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIaaalaaggANSP 200

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  94 ----SCLLLTTAIAIKLGLAPFHFWFPEVLQGSslttalllstlmklpPTTI-------------------LLLTSHSLN 150
Cdd:COG1007 201 llllGLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkiaafaallrlLVEAFPGLA 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 151 P---TLLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFYM--YTLMTTSIFLTL---- 219
Cdd:COG1007 266 AdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVIllls 345

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 220 -NTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAY 298
Cdd:COG1007 346 rKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 6.99e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 6.99e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    23 SNHWAMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQL-TYPPSC----- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    96 -----LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLM-KLPPTTILLLTS--HSLNPT---LLTAMSITSIAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   165 GGWMGLNQTQTRKILAFSSISHLGWMTMII----IYNPKLTLLTFYMYTLMTTSIFL-----TLNTTNTLKLSTLLTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 70955192   236 KTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-297 5.39e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 87.70  E-value: 5.39e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    23 SNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQLTYPPSC------ 95
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNgmlnis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    96 ------LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILL-------LTSHSLNPTLLTAMSITSI 162
Cdd:TIGR01770 201 llllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAWQIFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   163 ALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFY--MYTLMTTSIFLTL------NTTNTLKLSTLLT 232
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLsllrsyKDEWIEYISDFAG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70955192   233 SWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLA 297
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.37e-144

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 412.29  E-value: 1.37e-144
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    1 MGPFTKLISTTSLTLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWS 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   81 TGQWDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSIT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  241 NTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIKKP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 70955192  321 TNTLTPPITSLSILLLPLSPMILTTT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-329 5.91e-117

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 341.90  E-value: 5.91e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    1 MGPFTKLISTTSLTLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWS 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   81 TGQWDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSIT 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  241 NTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIKKP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                 ....*....
gi 70955192  321 TNTLTPPIT 329
Cdd:MTH00070 321 TNNLLSLTI 329
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 23-329 1.33e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 338.70  E-value: 1.33e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQLTYPPSCLLLTTAI 102
Cdd:MTH00135  23 SSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHPLPTTMITLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  103 AIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTtILLLTSHSLNPTLLTAMSITSIALGGWMGLNQTQTRKILAFS 182
Cdd:MTH00135 103 ALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNPTLLITLGLTSTLVGGWGGLNQTQLRKILAYS 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  183 SISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLP 262
Cdd:MTH00135 182 SIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMP 261

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 70955192  263 KWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIKKPTNTLTPPIT 329
Cdd:MTH00135 262 KWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAIS 328
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-329 6.66e-103

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 306.39  E-value: 6.66e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    1 MGPFTKLISTTSLTLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWS 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   81 TGQWDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSIT 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  241 NTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSN-KMK-QWSIK 318
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNmKMKwQFENT 320

                        330
                 ....*....|.
gi 70955192  319 KPTNTLTPPIT 329
Cdd:MTH00105 321 KPMTLLPTLII 331
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-324 2.00e-87

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 266.83  E-value: 2.00e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    1 MGPFTKLISTTSLTLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWS 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   81 TGQWDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSIT 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  161 SIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  241 NTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIKKP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320


                 ....
gi 70955192  321 TNTL 324
Cdd:MTH00200 321 SNLL 324
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 23-326 1.08e-76

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 239.45  E-value: 1.08e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQLTYPPSCLLLTTAI 102
Cdd:MTH00041  23 SNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSSIIITLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  103 AIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSITSIALGGWMGLNQTQTRKILAFS 182
Cdd:MTH00041 103 ALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKILAFS 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  183 SISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLP 262
Cdd:MTH00041 183 SIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGFLN 262

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 70955192  263 KWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIKKPTNTLTP 326
Cdd:MTH00041 263 KFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGV 326
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 23-329 5.98e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 175.01  E-value: 5.98e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWStgqwdiSQLTYPPSCLLLTTAI 102
Cdd:MTH00160  24 SNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN------LMLFNNISSMLINSSL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  103 AIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPttiLLLTSHSLNPTLLTAMSITSIALGGWMGLNQTQTRKILAFS 182
Cdd:MTH00160  98 LLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAP---LILLSYLINNNFIIIIIILSAIIGAIGGLNQTSLRKILAYS 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  183 SISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLP 262
Cdd:MTH00160 175 SINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLP 254

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 70955192  263 KWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITlppnpSNKMKQWSIKKPTNTLTPPIT 329
Cdd:MTH00160 255 KWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLML-----NYNKNKWNLKKKKNKFSLILN 316
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 23-318 4.83e-45

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 156.58  E-value: 4.83e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISqltyppscLLLTTAI 102
Cdd:MTH00144  23 SSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM--------SLLLLGL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  103 AIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPttILLLTSHSLNPTLLTA---MSITSIALGGWMGLNQTQTRKIL 179
Cdd:MTH00144  95 CLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAP--LFLLSNFLDLYWLAYLlcvISVLSALVGSIGGLNQTQVRALL 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  180 AFSSISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTlLTSWTKTPTLNTTLMLTLLSLAGLPPLTG 259
Cdd:MTH00144 173 AYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKD-LGSLKPSYKTGLSIISLLLSLGGLPPFLG 251

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 70955192  260 FLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMKQWSIK 318
Cdd:MTH00144 252 FCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNS 310
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 23-310 2.82e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 149.54  E-value: 2.82e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMnawstgQWDISQLTYPPSCLLLTTAI 102
Cdd:MTH00011  25 SNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWSFPSLLKNITALMLLVSL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  103 AIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSITSIALGGWMGLNQTQTRKILAFS 182
Cdd:MTH00011  99 MLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAYS 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  183 SISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLP 262
Cdd:MTH00011 179 SIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFMP 258

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 70955192  263 KWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYcSTITLPPNPSN 310
Cdd:MTH00011 259 KLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 23-313 5.06e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 138.27  E-value: 5.06e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTgqwdisqLTYPPSCLLLTTAI 102
Cdd:MTH00197  17 SSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL-------YLSLLSVVLVILGL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  103 AIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPttILLLTSHSLNPTLLTAMSITSIALGGWMGLNQTQTRKILAFS 182
Cdd:MTH00197  90 LLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGGIGGMNQSNIRQLLAYS 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  183 SISHLGWMTMIIIYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLP 262
Cdd:MTH00197 168 SIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFFL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 70955192  263 KWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAYCSTITLPPNPSNKMK 313
Cdd:MTH00197 248 KWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMK 298
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-298 1.75e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 94.80  E-value: 1.75e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  23 SNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQL--------TYPP 93
Cdd:COG1007 121 ANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIaaalaaggANSP 200

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  94 ----SCLLLTTAIAIKLGLAPFHFWFPEVLQGSslttalllstlmklpPTTI-------------------LLLTSHSLN 150
Cdd:COG1007 201 llllGLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkiaafaallrlLVEAFPGLA 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 151 P---TLLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFYM--YTLMTTSIFLTL---- 219
Cdd:COG1007 266 AdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVIllls 345

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 220 -NTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAY 298
Cdd:COG1007 346 rKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 6.99e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 6.99e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    23 SNHWAMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQL-TYPPSC----- 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELsKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    96 -----LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLM-KLPPTTILLLTS--HSLNPT---LLTAMSITSIAL 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   165 GGWMGLNQTQTRKILAFSSISHLGWMTMII----IYNPKLTLLTFYMYTLMTTSIFL-----TLNTTNTLKLSTLLTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 70955192   236 KTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 23-296 2.76e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 90.47  E-value: 2.76e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDI-------------SQ 88
Cdd:MTH00196  12 SSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinlvlnsgqsfSS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   89 LTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLltSHSLNPTLLTAMSITSIALGGWM 168
Cdd:MTH00196  92 VSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGGLFSLFVGAIG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  169 GLNQTQTRKILAFSSISHLGWMTMII----IYNPKLTLLTFYMYTLMTTSIFLTLNTTNTLK-----LSTLLtswTKTPT 239
Cdd:MTH00196 170 ALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALNVYKnliieFSGLS---RRLPI 246

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 70955192  240 LNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRL 296
Cdd:MTH00196 247 LAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
23-296 1.35e-19

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 89.49  E-value: 1.35e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQL--------TYPP 93
Cdd:PRK05777 122 ANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIakaladgsGNSL 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   94 ----SCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKL----PPTTILLLTSHSLNPT---LLTAMSITSI 162
Cdd:PRK05777 202 lllfGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqqVLAIIAIASM 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  163 ALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFYM--YTLMTTSIF--LTLNTTNTLKLSTLlTSWT- 235
Cdd:PRK05777 282 LVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYLlaYLFMTLGAFgvISLLRRKGGEAESI-SDFAg 360

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 70955192  236 ---KTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRL 296
Cdd:PRK05777 361 lskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-297 5.39e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 87.70  E-value: 5.39e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    23 SNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQLTYPPSC------ 95
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNgmlnis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    96 ------LLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILL-------LTSHSLNPTLLTAMSITSI 162
Cdd:TIGR01770 201 llllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLrlflyilFGFSEAWQIFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   163 ALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTL--LTFY--MYTLMTTSIFLTL------NTTNTLKLSTLLT 232
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLsllrsyKDEWIEYISDFAG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70955192   233 SWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLA 297
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-296 1.56e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 80.19  E-value: 1.56e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  30 WTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQL-----TYPPS-----CLLLT 99
Cdd:COG0651 133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaarlaELDPGlllaaFALLL 212

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 100 TAIAIKLGLAPFHFWFPEVlqgsslttalllstlMKLPPT--------------------TILLLTSHSLNP---TLLTA 156
Cdd:COG0651 213 VGFGIKAALFPLHFWLPDA---------------YPAAPSpvsallsglltkvgvyailrVLTLLFGADPALflgTLLLV 277

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 157 MSITSIALGGWMGLNQTQTRKILAFSSISHLGWMTMII-IYNPK-LTLLTFYM--YTLMTTSIFLT----LNTTNTLKLS 228
Cdd:COG0651 278 LGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLgLGTPLgLAGALFHLlnHALAKALLFLAagaiERATGTRDLD 357

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 70955192 229 TLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRL 296
Cdd:COG0651 358 KLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 23-296 1.21e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 74.67  E-value: 1.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDI----SQLTYPPSCLL 97
Cdd:MTH00199 116 SINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginSILTGDVGKIL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   98 LTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAmsITSIALGGWMGLNQTQTRK 177
Cdd:MTH00199 196 ITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICA--VLSIIYGAIGALNQTKIKR 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  178 ILAFSSISHLGWMTMIIIYNP----KLTLLTFYMYTLMTT---SIFLTLNTTNTLKLSTLLTSwTKTPTLNTTLMLTLLS 250
Cdd:MTH00199 274 LLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSIcsfSIILSLKLTKGLIVEVSGLS-RKNPVIALTLALTFLS 352

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 70955192  251 LAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRL 296
Cdd:MTH00199 353 IAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 23-296 2.04e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 64.88  E-value: 2.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAI---------EATTKYFLTQAAASTLLLFSSMMNAWSTGQ---------- 83
Cdd:MTH00198 207 SANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegmlgtilsa 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   84 ----WDISQLTYPPSCLLLTTAIAIKLGLAPFHFWFPEVLQGSSLTTALLLSTLMKLppTTILLLTSHSLNPTLLTAMSI 159
Cdd:MTH00198 287 tletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITSKLLLSVAI 364

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  160 TSIALGGWMGLNQTQTRKILAFSSISHLGWMTMII-------IYNPKLTLLTFYMYTLMTTSIFLTLNTTNTL------- 225
Cdd:MTH00198 365 ISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVsagtyesLQASWTYAVTYLVSALASFTVICTLEEFGTRtptsrqr 444

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  226 -----------KLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGL---- 290
Cdd:MTH00198 445 dgsfgnynlvrRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSSLSIYYLVALFAIictc 524


                 ....*....
gi 70955192  291 ---FFYLRL 296
Cdd:MTH00198 525 isaFYYIRI 533
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-263 3.74e-09

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 57.71  E-value: 3.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   51 RAIEATTKYFLTQAAASTLLLFS-SMMNAWSTGQWDIS---------QLTYPPSCLL----LTTAIAIKLGLAPFHFWFP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGfSWLYGLSGGEIELQeivnglintQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  117 EVLQGSSLTTALLLSTLMKLP----PTTILLLTSHSLNP---TLLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAasalATRIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  190 MTM-IIIYNPKLTLLTfyMYTLMTTSIFLTLNTTNTLKLSTLLT----------SWTKTPTLNTTLMLTLLSLAGLPPLT 258
Cdd:CHL00049 319 VIIgIIVGDSNDGYAS--MITYMLFYIFMNLGTFACIVLFGLRTgtdnirdyagLYTKDPFLALSLALCLLSLGGIPPLA 396


                 ....*
gi 70955192  259 GFLPK 263
Cdd:CHL00049 397 GFFGK 401
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-298 1.59e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 55.66  E-value: 1.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   33 LEINTLAIIPLISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQLT--YPPSCLLLT------TAIAI 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAgaLAENPTVVTafgfvlLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  105 KLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPTLLTAMSItSIALGGWMGLNQT 173
Cdd:PRK08375 215 KAAVFPLHTWLPRaypaappvvtaLLSGLVTKVAVYALIRIYFTVFGGDFRFALGLGWLLAVLALL-SMLVGSLAALGQD 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  174 QTRKILAFSSISHLGWMTMIIIYNPKLTLL--TFYM--YTLMTTSIFLTLN----TTNTLKLSTLLTSWTKTPTLNTTLM 245
Cdd:PRK08375 294 DVKRVLAYSTVSQMGYILLGLALLTPLALAagLLHLlhHALMKGALFLAAGaievTYGTRRLSELSGLGRRMPLTAAAFA 373

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 70955192  246 LTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAY 298
Cdd:PRK08375 374 VASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-192 4.14e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 54.70  E-value: 4.14e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  38 LAIIP---LISKSHHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQW-----DISQLTYPPS-----CLLLTTAIAI 104
Cdd:COG1008 142 LMLIPmyfLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTaqlllFLAFFIAFAV 221

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 105 KLGLAPFHFWFPEVLQGSSlttalllstlmklPPTTILL---------------------LTSHSLNPTLLtAMSITSIA 163
Cdd:COG1008 222 KVPMFPFHTWLPDAHVEAP-------------TAGSVLLagvllkmggygllrfalplfpEASAYFAPLLA-ALGVIGII 287

                       170       180
                ....*....|....*....|....*....
gi 70955192 164 LGGWMGLNQTQTRKILAFSSISHLGWMTM 192
Cdd:COG1008 288 YGALVALAQTDLKRLIAYSSVSHMGFVLL 316
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-292 4.48e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 48.01  E-value: 4.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192    50 PRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQW----DISQLTYPPSC-----LLLTTAIAIKLGLAPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGTfdllELLNLPLPFGVqtwlfLAFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   120 QGSSLTTALLLSTLMKLPPTTILLL-------TSHSLNPtLLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLGWMTM 192
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFnlplfpdASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   193 IIIYNPKLTLL--TFYMYT--LMTTSIFLTLNT----TNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKW 264
Cdd:TIGR01972 311 GIFSFNELGISgaVFQMIShgLITAALFLLVGVlyerAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEF 390

                         250       260
                  ....*....|....*....|....*...
gi 70955192   265 LIIQELTKqemtaTATAIALLSLLGLFF 292
Cdd:TIGR01972 391 LILLGSFK-----VNPVVAFLAALGIVL 413
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-263 9.00e-06

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 47.35  E-value: 9.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   50 PRAIEATTKYFLTQAAASTLLLF-SSMMNAWSTGQWDIS----QLTYPPSCLLLTT------AIAIKLGLAPFHFWFPEV 118
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSaialALITSPSLGLALAlvfviaGIAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  119 LQGSSLTTALLLSTLMKLPPTTI---LLLTSHSLNPT----LLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLGWMT 191
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  192 MIIIYNPK--LTLLTFYM--YTLMT----TSIFLTLNTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK02504 317 IGLVAGTEagYASMVFYLlaYLFMNlgafACVILFSLRTGTDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 6.11e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 44.70  E-value: 6.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   33 LEINTLAIIPLIS-KSHHPRAIEATTKYFLTQAAASTLLLFSSMMnawSTGQWDI-------SQLTYPPSCL------LL 98
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGIAL---LYGQYGTlnmaylaVKMSENPTVVakialaLF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   99 TTAIAIKLGLAPFHFW----FPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPT----LLTAMSITSIALGGWMGL 170
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWlpdaYPAAPSSISAMLLVIKQAGLYALARVLFSIYGPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  171 NQTQTRKILAFSSISHLGWMTM---IIIYNPKLTLLTFYMYTLMTTSIFLTLN--------------------TTNTLKL 227
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLLglgVGLAALGDPAMASYGEIALAGGIYHIVNhalykallfltagaviyetgTRNLNEL 386

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 70955192  228 STLLTSWTKTPTLNTTLMLTLlslAGLPPLTGFLPKWLI 266
Cdd:PRK08376 387 GGLARTMPKTTIAFLIGAAAI---VGLPPFNGFASKWLI 422
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-298 6.37e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 44.60  E-value: 6.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   34 EINTLA---IIPLISKshhpRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQ----LTYPPS-------CLLLT 99
Cdd:PRK08668 128 EIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADisqgLINDTStgfalivFLFLL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  100 TAIAIKLGLAPFHFWFPE-----------VLQGSSLTT-ALLLSTLMKLPPTTILLLT-----SHSLNPTLLTAMSITSI 162
Cdd:PRK08668 204 AFGVAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLgAYGFLLVLYVLPGTKLFSEfgtyrGVPLFNYILAWLGNISI 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  163 ALGGWMGLNQTQTRKILAFSSISHLGWmtmIIIYNPKLTLLTF-------YMYTLMTTSIFLTLNT----TNTLKLSTLL 231
Cdd:PRK08668 284 IVGTLMAILQEDIKKLIAYSSVANGGY---ILVGLGLGTSLGFagglfhvFNHALFKGLFFLIFAAviyrTGTTKISEMG 360

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 70955192  232 TSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALLSLLGLFFYLRLAY 298
Cdd:PRK08668 361 GLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 80-263 8.96e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 44.53  E-value: 8.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   80 STGQWDISQL-TYPPSCLLLTTAIAI-------KLGLAPFHFWFPEVLQGSSLTTALLLSTLM---------KLPPTtil 142
Cdd:PRK12644 183 AAGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMvkagiylvaRLAPG--- 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  143 LLTSHSLNPTLLTAMSITSIaLGGWMGLNQTQTRKILAFSSISHLGWMTMII-IYNPKLTLLTFYM---YTLMTTSIFLT 218
Cdd:PRK12644 260 FADVPVWRPTVLVLGLATML-LGGWRALRQHDLKLILAYGTVSQLGFLTVLVgIGTRDAALAGLAMllaHALFKAALFLV 338

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 70955192  219 L----NTTNTLKLSTLLTSWTKTPTLNTTLMLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12644 339 VgiidHSTGTRDIRKLSGLGRRQPVLAVVAALAAASMAGLPPLLGFVAK 387
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 48-298 1.42e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 43.60  E-value: 1.42e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  48 HHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQL-----------TYPPSCLLLTTAIAIKLGLAPFHFWFP 116
Cdd:COG1009 156 EKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELlaaaptilsspLLTLILLLLLLGAFGKSAQFPLHFWLP 235

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 117 EVLQGsslttalllstlmklpPTTI---------------LLLTSH---SLNPTLLTAMSITSIA---LGGWMGLNQTQT 175
Cdd:COG1009 236 DAMEG----------------PTPVsallhaatmvkagvyLLARLSplfALSPVWLTVVAIIGAItalFAALIALAQTDI 299

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192 176 RKILAFSSISHLGWMTMIIiynpKLTLLTFYMYTLMTTSIF------------LTLNTTNTLKLSTLltsWTKTPTLNTT 243
Cdd:COG1009 300 KRVLAYSTVSQLGYMFLAL----GVGAYVAALFHLLTHAFFkallflgagsviHATGTRDIRKMGGL---RKKMPITAIT 372

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 70955192 244 LMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMTATATAIALL--SLLGLFFYLRLAY 298
Cdd:COG1009 373 FLIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLLLAVALlgAFLTAFYSFRLFF 429
PRK12650 PRK12650
DUF4040 family protein;
29-304 4.30e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 42.34  E-value: 4.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   29 AWtglEINTLAIIPLISKSHhPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQLTYPPSCL---LLTTAIAIK 105
Cdd:PRK12650 138 AW---ELVSLASFFLIARSG-SGGEAGSIRTLILTFFGGLTLLAAVAIAATQTGTTSLSGILHSDVWAekpGLTTVVAVL 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  106 LGLA--------PFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSL--NPT----LLTAMSITSIaLGGWMGLN 171
Cdd:PRK12650 214 IAVAaftksaqfPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwlLIIVGMITAL-MGAVFAVQ 292

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  172 QTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYT----LMTTSIFLTL----NTTNTLKLSTLLTSWTKTPTLNTT 243
Cdd:PRK12650 293 KTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTlahaLFKSSLFMLIgvvdHQAGTRDIRRLGSLWRRMPFTFVS 372

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 70955192  244 LMLTLLSLAGLPPLTGFLPKWLIIQELTKQEMtATATAIALLSLLGLFFYLRLAYCSTITL 304
Cdd:PRK12650 373 VTIAALSMAAVPPLFGFVSKEGMLTAFLEAPG-GNAGVVLLLVGAALGAVFTFAYSARLVL 432
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 38-194 1.73e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 40.19  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   38 LAIIP---LISKSHHPRAIEATTKYFLTQAAASTLLLFSSM----MNAWSTGQWDISQLTYPPSCLLLTT--------AI 102
Cdd:PRK05846 142 AMLIPmyfLIGVWGGKNRIYAATKFFLYTLLGSLLMLVAIIylvvVYYNATGTFDIADLLNLPLPPGVQYwlflaffiAF 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  103 AIKLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPpttILLLTSHSLNPtLLTAMSITSIALGGWMGLN 171
Cdd:PRK05846 222 AVKMPMFPLHTWLPDahvqaptagsvLLAGILLKMGAYGLLRFSLP---LFPDASHEFAP-IIITLGVIAIIYGALVALA 297

                        170       180
                 ....*....|....*....|...
gi 70955192  172 QTQTRKILAFSSISHLGWMTMII 194
Cdd:PRK05846 298 QTDIKKLIAYSSISHMGFVTLGI 320
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-192 2.00e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 40.20  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   48 HHPRAIEATTKYFLTQAAASTLLLFSSMMNAWSTGQWDISQLTYPPSC--------LLLTTAIAIKLGLA------PFHF 113
Cdd:PRK12649 156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELienikghpLFLITLILIFIGAAaksaqgPFYI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192  114 WFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLNPT-----LLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLG 188
Cdd:PRK12649 236 WLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQLA 315


                 ....*
gi 70955192  189 W-MTM 192
Cdd:PRK12649 316 YlMTM 320
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 23-210 2.05e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 39.74  E-value: 2.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLTQAAA------STLLLFSSMMNAWSTGQWDISQLT-----Y 91
Cdd:PRK08676 121 SDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWTELAahaslL 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   92 PPSCLLLT-----TAIAIKLGLAPFHFWFPEV-LQGSSLTTALLLSTLMKLPPTTILLLTS-------HSLNPTLLTAMS 158
Cdd:PRK08676 201 SPSVLGASflfifIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRLSAllrqsgaAEQFSNVLIGLG 280

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 70955192  159 ITSIALGGWMGLNQTQTRKILAFSSISHLGWMTMIIIYNPKLTLLTFYMYTL 210
Cdd:PRK08676 281 IFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 23-191 5.29e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 38.37  E-value: 5.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   23 SNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFL------TQAAASTLLLFSSMMNAWSTGQWDI--SQLTYPPS 94
Cdd:PRK06458 127 SNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDGEMAIlwTELLKHAS 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   95 CL---LLTTAIAI-------KLGLAPFHFWFPE-----------VLQGSSLTTALLLSTLMKLppttILLLTSHSLNP-T 152
Cdd:PRK06458 207 LLdptLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYI----LIDAAIGSDFPgR 282

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 70955192  153 LLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLGWMT 191
Cdd:PRK06458 283 LLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIA 321
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-188 7.26e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 38.09  E-value: 7.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 70955192   55 ATTKYFLTQAAASTLLLFSSMMNAWSTGQ--WDISQLT---YPPSCLLLT-----TAIAIKLGLAPFHFWFPE------- 117
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGaksYPLALELLLyagflIAFGVKLPIFPLHTWLPDahgeasa 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 70955192  118 ----VLQGSSLTTALLLSTLMKLPpttiLLLTSHSLNPTLLTAMSITSIALGGWMGLNQTQTRKILAFSSISHLG 188
Cdd:PRK12561 218 pvsmILAGVLLKMGGYALIRFNVQ----MLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMG 288
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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