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Conserved domains on  [gi|126466709|gb|ABO14107|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Xiphophorus evelynae]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 519.75  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 TGGWDILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPDNPNVFITLGLLS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 161 VIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 241 ACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRLNPQH 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 126466709 321 NTLPLALTTTTTIYLLPVTPAILALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 519.75  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 TGGWDILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPDNPNVFITLGLLS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 161 VIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 241 ACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRLNPQH 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 126466709 321 NTLPLALTTTTTIYLLPVTPAILALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-314 6.24e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.26  E-value: 6.24e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPL-MTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAF 79
Cdd:COG1007   99 LLRGEFYALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYG 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  80 LTGGWDILQINHPLTSTLTTLALAM------------KIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQI-- 145
Cdd:COG1007  179 ATGSLNLAGIAAALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlv 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 146 ------QPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILIL----PFSPPLTLLALFTYLMMTFSLF 215
Cdd:COG1007  259 eafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAF 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 216 SSFMLVR-----TTHINSLSTSWAKIPTLTAC----------VPlillslgglpPLTGFLPKWLILQELTKQDLAPIATL 280
Cdd:COG1007  339 AVILLLSrkggeAEEIEDLAGLARRSPLLALAmtifllslagIP----------PTAGFFGKFYVFSAAVEAGLYWLAVI 408

                        330       340       350
                 ....*....|....*....|....*....|....
gi 126466709 281 AALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPW 314
Cdd:COG1007  409 AVLNSVISAYYYLRVVKAMYFDEPEEEAPISAPP 442
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 6.26e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.22  E-value: 6.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   23 STHWYLAWMGIEINTLAIIPLMTQNH-NPRAIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQINHPLTSTLTTLA 101
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGkSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  102 LAM-----------KIGLAPLHSWMPEVMQGLNLLTGLIL-STWQKLAPFCLIYQIQPDNP------NVFITLGLLSVIV 163
Cdd:pfam00361  81 LLLlfllilvgflfKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLLYLPsspfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  164 GGWGGFNQVQLRKILAYSSIAHLGWMILIL----PFSPPLTLLALFTYLMMTFSLFSSFMLV-----RTTHINSLSTSWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSViyrrvHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 126466709  235 KIPTLTACVPLILLSLGGLPPLTGFLPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-305 3.25e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 79.22  E-value: 3.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709    4 FVYSTLIISLGLgttMTFAST-HWYLAWMGIEINTLAIIPLMT-QNHNPRAIEATTKYFFAQATASATLLFAAVSNAFLT 81
Cdd:TIGR01770 104 FYILLLFALLGI---FLLVSSnDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFT 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   82 GGWDILQINHPLTSTLTTLAL------------AMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCL-------- 141
Cdd:TIGR01770 181 GSLNFEDLLLFLSNGMLNISLlllgivlilvglLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVflrlflyi 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  142 IYQIQPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSP----PLTLLALFTYLMMTFSLFSS 217
Cdd:TIGR01770 261 LFGFSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  218 FMLVRTT------HINSLSTSWAKIPTLTACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYF 291
Cdd:TIGR01770 341 LSLLRSYkdewieYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420

                         330
                  ....*....|....
gi 126466709  292 YLRLSYTMTLTMPP 305
Cdd:TIGR01770 421 YLRVVKVMYFDKPE 434
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 519.75  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 TGGWDILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPDNPNVFITLGLLS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 161 VIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 241 ACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRLNPQH 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 126466709 321 NTLPLALTTTTTIYLLPVTPAILALFT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 1.75e-137

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 394.29  E-value: 1.75e-137
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 TGGWDILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPD-NPNVFITLGLL 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 160 SVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 240 TACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRLNPQ 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                        330       340
                 ....*....|....*....|....*..
gi 126466709 320 HNtLPLALTTTTTIYLLPVTPAILALF 346
Cdd:MTH00070 321 TN-NLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 4.93e-119

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 347.20  E-value: 4.93e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 TGGWDILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPD-NPNVFITLGLL 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 160 SVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 240 TACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRLNPQ 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 126466709 320 HNtLPLALTTTTTIYLLPVTPAILALF 346
Cdd:MTH00112 321 KN-TLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 3.00e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 337.97  E-value: 3.00e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 TGGWDILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPD-NPNVFITLGLL 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 160 SVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 240 TACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRLNPQ 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 126466709 320 HNTLPLALTTTTTIYLLPVTPAILALF 346
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 1.72e-100

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 300.35  E-value: 1.72e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 TGGWDILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPD-NPNVFITLGLL 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPAlNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 160 SVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 240 TACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRlNPQ 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWR-TKS 319

                        330       340
                 ....*....|....*....|....*...
gi 126466709 320 HNTLPLALTTTTTIYLLPVTPAILALFT 347
Cdd:MTH00200 320 NSNLLVGLLLLLSILGLPLTPQLLFLFF 347
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 5-317 2.07e-79

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 246.38  E-value: 2.07e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   5 VYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFLTGGW 84
Cdd:MTH00041   5 VLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  85 DILQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPF-CLIYQIQPDNPNVFITLGLLSVIV 163
Cdd:MTH00041  85 SINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLiLLISISNLLNSNILILCGILSVLV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 164 GGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLTACV 243
Cdd:MTH00041 165 GGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLF 244

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126466709 244 PLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPWRLN 317
Cdd:MTH00041 245 ILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNS 318
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-307 9.04e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 187.72  E-value: 9.04e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFL 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  81 tggwdiLQINHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQpdNPNVFITLGLLS 160
Cdd:MTH00160  82 ------LMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI--NNNFIIIIIILS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 161 VIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLT 240
Cdd:MTH00160 154 AIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIK 233

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 126466709 241 ACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPNN 307
Cdd:MTH00160 234 FLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-303 1.28e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 166.21  E-value: 1.28e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  13 LGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILqinhp 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  93 ltsTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPDNP--NVFITLGLLSVIVGGWGGFN 170
Cdd:MTH00144  88 ---SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 171 QVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLTACVPLIlLSL 250
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLL-LSL 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 126466709 251 GGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTM 303
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSS 296
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 12-304 2.54e-44

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 154.94  E-value: 2.54e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  12 SLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFLTGgwdilQINH 91
Cdd:MTH00011  14 TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPS-----LLKN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  92 PLTSTLTTLALaMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPDNPNVFIT-LGLLSVIVGGWGGFN 170
Cdd:MTH00011  89 ITALMLLVSLM-LKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTsMAAMSALAGGLGGMN 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 171 QVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLTACVPLILLSL 250
Cdd:MTH00011 168 QTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 126466709 251 GGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMP 304
Cdd:MTH00011 248 GGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSP 301
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 11-298 1.54e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 142.12  E-value: 1.54e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  11 ISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFaavsnafltGGWDILQIN 90
Cdd:MTH00197   5 FIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLSFSNL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  91 HPLTSTLTTLAL--AMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQpDNPNVFITLGLLSVIVGGWGG 168
Cdd:MTH00197  76 YLSLLSVVLVILglLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNS-SSFMGLLICSVLSSLIGGIGG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 169 FNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLSTSWAKIPTLTACVPLILL 248
Cdd:MTH00197 155 MNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFL 234

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 126466709 249 SLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYT 298
Cdd:MTH00197 235 SLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYK 284
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-295 1.35e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 99.72  E-value: 1.35e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  15 LGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNP-RAIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQIN--- 90
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSYINlvl 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  91 ----------HPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPdNPNVFITLGLLS 160
Cdd:MTH00196  84 nsgqsfssvsVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL-NVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 161 VIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPF----SPPLTLLALFTYLMMTFSLFSSFMLVRTTH--INSLSTSWA 234
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSGLSR 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 126466709 235 KIPTLTACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRL 295
Cdd:MTH00196 243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-314 6.24e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.26  E-value: 6.24e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   1 MAPFVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPL-MTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAF 79
Cdd:COG1007   99 LLRGEFYALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYG 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  80 LTGGWDILQINHPLTSTLTTLALAM------------KIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQI-- 145
Cdd:COG1007  179 ATGSLNLAGIAAALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlv 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 146 ------QPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILIL----PFSPPLTLLALFTYLMMTFSLF 215
Cdd:COG1007  259 eafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAF 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 216 SSFMLVR-----TTHINSLSTSWAKIPTLTAC----------VPlillslgglpPLTGFLPKWLILQELTKQDLAPIATL 280
Cdd:COG1007  339 AVILLLSrkggeAEEIEDLAGLARRSPLLALAmtifllslagIP----------PTAGFFGKFYVFSAAVEAGLYWLAVI 408

                        330       340       350
                 ....*....|....*....|....*....|....
gi 126466709 281 AALSSLFSLYFYLRLSYTMTLTMPPNNPAGTLPW 314
Cdd:COG1007  409 AVLNSVISAYYYLRVVKAMYFDEPEEEAPISAPP 442
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 6.26e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.22  E-value: 6.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   23 STHWYLAWMGIEINTLAIIPLMTQNH-NPRAIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQINHPLTSTLTTLA 101
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGkSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  102 LAM-----------KIGLAPLHSWMPEVMQGLNLLTGLIL-STWQKLAPFCLIYQIQPDNP------NVFITLGLLSVIV 163
Cdd:pfam00361  81 LLLlfllilvgflfKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLLYLPsspfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  164 GGWGGFNQVQLRKILAYSSIAHLGWMILIL----PFSPPLTLLALFTYLMMTFSLFSSFMLV-----RTTHINSLSTSWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSViyrrvHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 126466709  235 KIPTLTACVPLILLSLGGLPPLTGFLPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
5-316 9.58e-20

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 89.88  E-value: 9.58e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   5 VYSTLIISLgLGTTMTFASTHWYLAWMGIEINTLAIIPL-MTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFLTGG 83
Cdd:PRK05777 105 FYLLVLFAL-LGMMVMVSANDLLTLFLGLELLSLPLYALaALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGS 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  84 WDILQINHPLTSTLTTLALAM------------KIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQI------ 145
Cdd:PRK05777 184 LSFAGIAKALADGSGNSLLLLfglvfllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvafg 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 146 --QPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPL----TLLALFTYLMMTFSLFSSFM 219
Cdd:PRK05777 264 glSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLGAFGVIS 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 220 LVR-----TTHINSLSTSWAKIPTLTACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLR 294
Cdd:PRK05777 344 LLRrkggeAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423

                        330       340
                 ....*....|....*....|..
gi 126466709 295 LSYTMTLTMPPNNPAGTLPWRL 316
Cdd:PRK05777 424 VIKLMYFDEPPRDAPVNWPLSA 445
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-295 5.12e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 87.76  E-value: 5.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   4 FVYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNP-RAIEATTKYFFAQATASATLLFAAVSNAFLTG 82
Cdd:MTH00199  97 QSSPILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSaYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  83 GWDILQINHPLTS----TLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPDNpNVFITLGL 158
Cdd:MTH00199 177 ETSIQGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVT-NVVLICAV 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 159 LSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPF----SPPLTLLALFTYLMMTFSLFSSFMLVRTTH--INSLSTS 232
Cdd:MTH00199 256 LSIIYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIgsfeSIQASLIYMIIYVIMSICSFSIILSLKLTKglIVEVSGL 335

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 126466709 233 WAKIPTLTACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRL 295
Cdd:MTH00199 336 SRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 5-299 8.54e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 80.96  E-value: 8.54e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   5 VYSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASATLLFAAVSNAFLTGGW 84
Cdd:COG0651  108 RFYPLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTL 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  85 DILQINHPLTSTLTTLALA----------MKIGLAPLHSWMPE-----------VMQGLNLLTGL--ILSTWQKLAPFCL 141
Cdd:COG0651  188 NMADLAARLAELDPGLLLAafalllvgfgIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADP 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 142 IYQIQPdnpnVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYL----MMTFSLFSS 217
Cdd:COG0651  268 ALFLGT----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFLA 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 218 FMLVR----TTHINSLSTSWAKIPTLTACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYL 293
Cdd:COG0651  344 AGAIEratgTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFV 423


                 ....*.
gi 126466709 294 RLSYTM 299
Cdd:COG0651  424 RIFGRA 429
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-305 3.25e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 79.22  E-value: 3.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709    4 FVYSTLIISLGLgttMTFAST-HWYLAWMGIEINTLAIIPLMT-QNHNPRAIEATTKYFFAQATASATLLFAAVSNAFLT 81
Cdd:TIGR01770 104 FYILLLFALLGI---FLLVSSnDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFT 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   82 GGWDILQINHPLTSTLTTLAL------------AMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCL-------- 141
Cdd:TIGR01770 181 GSLNFEDLLLFLSNGMLNISLlllgivlilvglLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVflrlflyi 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  142 IYQIQPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSP----PLTLLALFTYLMMTFSLFSS 217
Cdd:TIGR01770 261 LFGFSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTlegiKAVLFYIFIYALMSLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  218 FMLVRTT------HINSLSTSWAKIPTLTACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYF 291
Cdd:TIGR01770 341 LSLLRSYkdewieYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420

                         330
                  ....*....|....
gi 126466709  292 YLRLSYTMTLTMPP 305
Cdd:TIGR01770 421 YLRVVKVMYFDKPE 434
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-223 8.49e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 56.79  E-value: 8.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   9 LIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAI---------EATTKYFFAQATASATLLFAAVSNAF 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  80 LTGGWDILQI--------------NHPLTSTLTTLALAMKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQI 145
Cdd:MTH00198 273 FTGNEGMLGTilsatlettnielrQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL 352

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 126466709 146 QPDNpNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYLMMTF-SLFSSFMLVRT 223
Cdd:MTH00198 353 VITS-KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTYLvSALASFTVICT 430
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 105-306 5.32e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 54.11  E-value: 5.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 105 KIGLAPLHSWMPEVMQGL-NLLTGLILSTWQKLAPFCLI----------YQIQPDNPNVFITLGLLSVIVGGWGGFNQVQ 173
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAApPVVTALLSGLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALLSMLVGSLAALGQDD 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 174 LRKILAYSSIAHLGWMILILPFSPPLTLLA----LFTYLMMTFSLF-SSFMLVRTTH---INSLSTSWAKIPTLTACVPL 245
Cdd:PRK08375 295 VKRVLAYSTVSQMGYILLGLALLTPLALAAgllhLLHHALMKGALFlAAGAIEVTYGtrrLSELSGLGRRMPLTAAAFAV 374

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 126466709 246 ILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMPPN 306
Cdd:PRK08375 375 ASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPP 435
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 1.46e-06

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 44.56  E-value: 1.46e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 126466709  290 YFYLRLSYTMTLTMPPNNPAGTLPWRLNPQHNTLPLALTTTTTIYLLPVTP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
ndhB CHL00049
NADH dehydrogenase subunit 2
 105-295 2.18e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 49.23  E-value: 2.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 105 KIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCL--------IYQIQPDNPNVFITLGLLSVIVGGWGGFNQVQLRK 176
Cdd:CHL00049 227 KLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALatrifdipFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKR 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 177 ILAYSSIAHLGW-MILILPFSPPL----TLLALFTYLMM---TFSLFSSFML-VRTTHINSLSTSWAKIPTLTACVPLIL 247
Cdd:CHL00049 307 MLAYSSIGQIGYvIIGIIVGDSNDgyasMITYMLFYIFMnlgTFACIVLFGLrTGTDNIRDYAGLYTKDPFLALSLALCL 386

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 126466709 248 LSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRL 295
Cdd:CHL00049 387 LSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 104-224 3.42e-06

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 48.51  E-value: 3.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 104 MKIGLAPLHSWMPEV-----MQGLNLLTGLILstwqKLAPFCLI---YQIQPDNPNVF----ITLGLLSVIVGGWGGFNQ 171
Cdd:MTH00217 218 IKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGYGFIrfsWPLLPEASEYFspliQTLSLLAIIYGSLTTCRQ 293

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 126466709 172 VQLRKILAYSSIAHLGWMILILpFSPPLTLLALFTYLMMTFSLFSSFMLVRTT 224
Cdd:MTH00217 294 VDLKRIIAYSSVAHMGLVTLGI-FSHTIQGLVAAIFLMLAHGLVSSALFIAVT 345
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-191 4.65e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 48.01  E-value: 4.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   50 PRAIEATTKYFFAQATASATLLFAAVSNAFLTGG-WDILQ-INHPLTSTLTTLALA-------MKIGLAPLHSWMPEVMQ 120
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLElLNLPLPFGVQTWLFLaffiafaVKVPLFPLHTWLPDAHV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  121 -----GLNLLTGLILstwqKLAPFCLI---YQIQPDNPNVF----ITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGW 188
Cdd:TIGR01972 232 eaptaGSVILAGVLL----KMGTYGFLrfnLPLFPDASLYFapvlAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGF 307


                  ...
gi 126466709  189 MIL 191
Cdd:TIGR01972 308 VLL 310
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 151-266 9.81e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 47.04  E-value: 9.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 151 NVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTYlMMTFSLFSS--FMLV------- 221
Cdd:PRK12662 280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAY-IVNHSIVKSalFMVSgsisyhf 358

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 126466709 222 RTTHINSLSTSWAKIPTLTACVPLILLSLGGLPPLTGFLPKWLIL 266
Cdd:PRK12662 359 GTTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
49-304 1.89e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 46.20  E-value: 1.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  49 NPRAIEATTKYFFAQATASATLLFAAVSNAFLTGGWDILQINHPLTSTLTTLALAM-----------KIGLAPLHSWMPE 117
Cdd:PRK02504 156 DPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGGSTQLSAIALALITSPSLGLALalvfviagiafKISAVPFHQWTPD 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 118 VMQGLNLLTGLILSTWQKLAPFCLIYQI--------QPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGW- 188
Cdd:PRK02504 236 VYEGSPTPVVAFLSVGSKAAGFALAIRLlvtafpsfDEQWKLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFv 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 189 MILILP-----FSPplTLLALFTYLMMTFSLFSSFML--VRT--THINSLSTSWAKIPTLTACVPLILLSLGGLPPLTGF 259
Cdd:PRK02504 316 MIGLVAgteagYAS--MVFYLLAYLFMNLGAFACVILfsLRTgtDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGF 393

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 126466709 260 LPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTMTLTMP 304
Cdd:PRK02504 394 FGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVIKMMVVKEP 438
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 105-191 3.73e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 45.19  E-value: 3.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 105 KIGLAPLHSWMPEVMQ-----GLNLLTGLILstwqKLAPFCLI---YQIQPDNPNVF----ITLGLLSVIVGGWGGFNQV 172
Cdd:PRK05846 224 KMPMFPLHTWLPDAHVqaptaGSVLLAGILL----KMGAYGLLrfsLPLFPDASHEFapiiITLGVIAIIYGALVALAQT 299

                         90
                 ....*....|....*....
gi 126466709 173 QLRKILAYSSIAHLGWMIL 191
Cdd:PRK05846 300 DIKKLIAYSSISHMGFVTL 318
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-208 4.19e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 45.13  E-value: 4.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  17 TTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATA------SATLLFAAVSNAFLTG--GWDILQ 88
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWTELA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  89 INHPLTSTLTTLALAM--------KIGLAPLHSWMPEV-MQGLNLLTGLILSTWQKLAPFCLIY--------QIQPDNPN 151
Cdd:PRK08676 195 AHASLLSPSVLGASFLfifigflaKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRlsallrqsGAAEQFSN 274

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 126466709 152 VFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLL-ALFTYL 208
Cdd:PRK08676 275 VLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFwMLFHML 332
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 50-191 5.33e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 44.69  E-value: 5.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  50 PRAIEATTKYFFAQATASATLLFAAVSNAFLTGGW-----DILQINHPLTSTLTTLALAM-----KIGLAPLHSWMPEVM 119
Cdd:COG1008  157 ERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAPLPLTAQLLLFLAFFiafavKVPMFPFHTWLPDAH 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 120 Q-----GLNLLTGLILstwqKLAPFCLI---YQIQPDNPNVF----ITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLG 187
Cdd:COG1008  237 VeaptaGSVLLAGVLL----KMGGYGLLrfaLPLFPEASAYFapllAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMG 312


                 ....
gi 126466709 188 WMIL 191
Cdd:COG1008  313 FVLL 316
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 105-299 2.61e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 42.65  E-value: 2.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 105 KIGLAPLHSWMPEV-----------MQGLNLLTG---------LILSTWQKLAPFCLIYQIqpdnpnVFITLGLLSVIVG 164
Cdd:PRK12667 236 KAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAALSP------ILIILGAVSAIIG 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 165 GWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLAlFTYLMMTFSLFSS--FMLV-------RTTHINSLSTSWAK 235
Cdd:PRK12667 310 ALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAA-ALFHIINHAIAKSllFLASgvfihaaGTRDIDELAGLGRK 388

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126466709 236 IPTLTACVPLILLSLGGLPPLTGFLPKWLILQELTKQDLAPIATLAALSSLFSLYFYLRLSYTM 299
Cdd:PRK12667 389 MPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSL 452
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 105-191 3.98e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.94  E-value: 3.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 105 KIGLAPLHSWMPEVMQGLN-----LLTGLILstwqKLAPFCLI---YQIQPDNPNVF----ITLGLLSVIVGGWGGFNQV 172
Cdd:PRK12561 198 KLPIFPLHTWLPDAHGEASapvsmILAGVLL----KMGGYALIrfnVQMLPDAHVYFapalAILGVVNIIYGALNAFAQD 273

                         90
                 ....*....|....*....
gi 126466709 173 QLRKILAYSSIAHLGWMIL 191
Cdd:PRK12561 274 NVKRRLAYSSVSHMGFVLL 292
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 28-203 6.66e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 41.45  E-value: 6.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  28 LAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFF------AQATASATLLFAAVSNaFLTGGWDILQINHPLTSTLTTLA 101
Cdd:PRK06458 132 LMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAAT-VMGDGEMAILWTELLKHASLLDP 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 102 LAM-------------KIGLAPLHSWMPEV-MQGLN----LLTGLILstwqKLAPFCLI--YQIQPDNP------NVFIT 155
Cdd:PRK06458 211 TLMklafvflligfgtKVGLFPMHAWLPDAhSEAPSpvsaLLSGVLL----NVALYAVLryYILIDAAIgsdfpgRLLLI 286

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 126466709 156 LGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLA 203
Cdd:PRK06458 287 FGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFA 334
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
104-202 7.93e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 41.24  E-value: 7.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 104 MKIGLAPLHSWMP----EVMQGLNLLTGLILStwqKLAPFCLI---YQIQPDNPNVF----ITLGLLSVIVGGWGGFNQV 172
Cdd:PRK07363 217 IKIPLVPLHTWLPdaytEASPAVAILLGGVLA---KLGTYGLLrfgLQLFPQTWSLVapglAIIGTISVIYGALSAIAQK 293

                         90       100       110
                 ....*....|....*....|....*....|
gi 126466709 173 QLRKILAYSSIAHLGWMILILPFSPPLTLL 202
Cdd:PRK07363 294 DIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
104-221 8.50e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.22  E-value: 8.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 104 MKIGLAPLHSWMPE-----------VMQG--LNLLT--------GLILSTWQKLAPFcliyqiqpdnpnvFITLGLLSVI 162
Cdd:PRK06473 217 IKIPLVPFHTWLPDahveastpvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLAPW-------------LATWAVVSVL 283

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 126466709 163 VGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALfTYLMMTFSLFSS--FMLV 221
Cdd:PRK06473 284 YGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILAA-VFQMISHGLISAllFLLV 343
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 104-231 2.70e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 39.08  E-value: 2.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 104 MKIGLAPLHSWMPEVMQGLNLLTGLILSTWQKLAPFCLIYQIQPDNPNVFITLGLLSVIVGGWGGFNqvqLRKILAYSSI 183
Cdd:MTH00091  69 MKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMFLLKS---YKNLLILSST 145

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 126466709 184 AHLGWMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTTHINSLST 231
Cdd:MTH00091 146 ESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWET 193
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 104-224 4.19e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 38.75  E-value: 4.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 104 MKIGLAPLHSWMPEV-----MQGLNLLTGLILstwqKLAPFCLIYQIQPDNP-------NVFITLGLLSVIVGGWGGFNQ 171
Cdd:MTH00226 242 VKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLVRLSWPILPlgaqnlaPAVIAMGIVGIVYGSFATCRQ 317

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 126466709 172 VQLRKILAYSSIAHLGwMILILPFSPPLTLLALFTYLMMTFSLFSSFMLVRTT 224
Cdd:MTH00226 318 IDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIMLAHGIVSSLLFILVT 369
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 152-221 4.66e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 38.75  E-value: 4.66e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 126466709 152 VFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILILPFSPPLTLLALFTyLMMTFSLFSS--FMLV 221
Cdd:PRK12644 269 TVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLA-MLLAHALFKAalFLVV 339
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 111-196 5.40e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 38.52  E-value: 5.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 111 LHSWMPEVMQGLNLLTGLI-LSTWQKLAPFCLI-----YQIQPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIA 184
Cdd:MTH00020 229 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLLIrssplFEQAPLALIIVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCS 308

                         90
                 ....*....|..
gi 126466709 185 HLGWMILILPFS 196
Cdd:MTH00020 309 QLGYMVVACGLS 320
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-193 5.71e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 38.40  E-value: 5.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709 111 LHSWMPEVMQGLNLLTGLI-LSTWQKLAPFCLI-----YQIQPDNPNVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIA 184
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLMIrsfplFEKAPLTLLIITIFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                 ....*....
gi 126466709 185 HLGWMILIL 193
Cdd:MTH00032 324 QLGYMVLII 332
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 6-193 8.12e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 37.82  E-value: 8.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709   6 YSTLIISLGLGTTMTFASTHWYLAWMGIEINTLAIIPLMTQNHNPRAIEATTKYFFAQATASAtllFAAVSNAFLTGGWD 85
Cdd:PRK08377 110 YAMLFLLLMLGATGMIATGDIFNLFVFMEITAITAYALTAYNKTGEAAEASMKYIVLGGIGSS---FFLIGVALIYGATG 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126466709  86 ILQINHPLTSTLTTLALAMKIGLA-------------PLHSWMPEVMQGL-NLLTGLILSTWQKLAPFCL---IYQIQPD 148
Cdd:PRK08377 187 TLNMAHIAQLAGTIDPTVAQVGLAllifglaveaelfPLNAWAPDAYQAApHPITVMFSAFVVKAGLYAMariLYLMQNA 266

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 126466709 149 NP-----NVFITLGLLSVIVGGWGGFNQVQLRKILAYSSIAHLGWMILIL 193
Cdd:PRK08377 267 NGwssvlKLVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALAL 316
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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