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Conserved domains on  [gi|146746484|gb|ABQ43620|]
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vCCP/EEV host range protein [Tanapox virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02831 PHA02831
EEV host range protein; Provisional
 1-268 2.71e-169

EEV host range protein; Provisional


:

Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 468.32  E-value: 2.71e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484   1 MINLTKIIILSFISKTWCICVFNKNDAKYSNVDSYENKVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKTNCKD 80
Cdd:PHA02831   1 MINLTKIIILLFISKTWCICVFNKNDAKYSNVDSYENKVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRNCKD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  81 PVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSIVGNETVKCINKQWIPKYPVCKLIRCKYPALQNGFLNVFEKKFYY 160
Cdd:PHA02831  81 PVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSIVGNETVKCINKQWVPKYPVCKLIRCKYPALQNGFLNVFEKKFYY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 161 GDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVNNVIQPNYLFDDLDEDFNNSTTNYNAQQNIITIIILLSII 240
Cdd:PHA02831 161 GDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHNEIQPNYLFDDLDEDFNNSTTNYNMQQNIITIIILLSII 240

                        250       260
                 ....*....|....*....|....*...
gi 146746484 241 CFIFVLGLIALFLSCNKSTLKPSIYNKF 268
Cdd:PHA02831 241 CFIFVLGLIALFLSCNKSTLKPSIYNKF 268
 
Name Accession Description Interval E-value
PHA02831 PHA02831
EEV host range protein; Provisional
 1-268 2.71e-169

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 468.32  E-value: 2.71e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484   1 MINLTKIIILSFISKTWCICVFNKNDAKYSNVDSYENKVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKTNCKD 80
Cdd:PHA02831   1 MINLTKIIILLFISKTWCICVFNKNDAKYSNVDSYENKVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRNCKD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  81 PVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSIVGNETVKCINKQWIPKYPVCKLIRCKYPALQNGFLNVFEKKFYY 160
Cdd:PHA02831  81 PVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSIVGNETVKCINKQWVPKYPVCKLIRCKYPALQNGFLNVFEKKFYY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 161 GDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVNNVIQPNYLFDDLDEDFNNSTTNYNAQQNIITIIILLSII 240
Cdd:PHA02831 161 GDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHNEIQPNYLFDDLDEDFNNSTTNYNMQQNIITIIILLSII 240

                        250       260
                 ....*....|....*....|....*...
gi 146746484 241 CFIFVLGLIALFLSCNKSTLKPSIYNKF 268
Cdd:PHA02831 241 CFIFVLGLIALFLSCNKSTLKPSIYNKF 268
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 144-196 1.43e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 1.43e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 146746484 144 PALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 144-195 3.75e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 3.75e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 146746484   144 PALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
78-136 1.44e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.19  E-value: 1.44e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484   78 CKDPVTILNGYIKNKKDQYSFGDSVTYACKVNklekYSIVGNETVKCI-NKQWIPKYPVC 136
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPG----YRLVGSPTITCQeDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02831 PHA02831
EEV host range protein; Provisional
 1-268 2.71e-169

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 468.32  E-value: 2.71e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484   1 MINLTKIIILSFISKTWCICVFNKNDAKYSNVDSYENKVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKTNCKD 80
Cdd:PHA02831   1 MINLTKIIILLFISKTWCICVFNKNDAKYSNVDSYENKVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRNCKD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  81 PVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSIVGNETVKCINKQWIPKYPVCKLIRCKYPALQNGFLNVFEKKFYY 160
Cdd:PHA02831  81 PVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSIVGNETVKCINKQWVPKYPVCKLIRCKYPALQNGFLNVFEKKFYY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 161 GDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVNNVIQPNYLFDDLDEDFNNSTTNYNAQQNIITIIILLSII 240
Cdd:PHA02831 161 GDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHNEIQPNYLFDDLDEDFNNSTTNYNMQQNIITIIILLSII 240

                        250       260
                 ....*....|....*....|....*...
gi 146746484 241 CFIFVLGLIALFLSCNKSTLKPSIYNKF 268
Cdd:PHA02831 241 CFIFVLGLIALFLSCNKSTLKPSIYNKF 268
PHA02639 PHA02639
EEV host range protein; Provisional
 40-268 1.62e-42

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 146.73  E-value: 1.62e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  40 YEENENLEYKCNNNFDKV---FVTC----NNGSWSTKNMCIGKTNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLE 112
Cdd:PHA02639  40 YEIGKLIEYTCNTDYALIgdrFRTCikdkNNAIWSNKAPFCMLKECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHKGV 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 113 KYSIVGNETVKCI-NKQWIPKYPVCKLIRCKYPALQNGFLNVF--EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWY 189
Cdd:PHA02639 120 QYSLVGNEKITCIqDKSWKPDPPICKMINCRFPALQNGYINGIpsNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWF 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 190 PGIPKCVKDK-VNNVIQPNYL---FDDLDEDFNNSTTNYNAQQNIITIIILLSI------------ICFIFVLGLIALFL 253
Cdd:PHA02639 200 PSIPTCVRNKpIDDIIYLKPVddnFDDLDNEDKINTILHNNDANSTRINQEKENgniftviillsiISFMFILGVLSLLC 279

                        250
                 ....*....|....*.
gi 146746484 254 SCN-KSTLKPSIYNKF 268
Cdd:PHA02639 280 SCMlKSSSKTSVYNKL 295
PHA02817 PHA02817
EEV Host range protein; Provisional
 78-267 3.59e-34

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 123.13  E-value: 3.59e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  78 CKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLE-KYSIVGNETVKC-INKQWIPKYPVCKLIRCKYPALQNGFLNVF- 154
Cdd:PHA02817  24 CCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRGvRYTLVGEKNIICeKDGKWNKEFPVCKIIRCRFPALQNGFVNGIp 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 155 -EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVK-DKVNNVI--QPNYLFDDLDEDFNNSTTNY-----N 225
Cdd:PHA02817 104 dSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRdNITYNKIyiNKVNIDDNFFNQINNSNTYYfdkilQ 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 146746484 226 AQQNIITIIILLSIICFIFVLGLIALFLSCNKSTLKPSIYNK 267
Cdd:PHA02817 184 INNVNRYTLIFFVVVSIKILFGFVFIFFSCNKKPLDSIKYYK 225
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 45-197 9.40e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 99.34  E-value: 9.40e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  45 NLEYKCNNNFDKVFVT---CNNGS-----WSTKNMCIGKTNCKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSI 116
Cdd:PHA02927 107 SITYSCNSGYQLIGESksyCELGStgsmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCN----SGYSL 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 117 VGNETVKCINKQWiPKYPVCKLIRCKYPALQNGFLNV-FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
Cdd:PHA02927 183 IGNSGVLCSGGEW-SDPPTCQIVKCPHPTISNGYLSSgFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKC 261


                 ..
gi 146746484 196 VK 197
Cdd:PHA02927 262 VR 263
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 35-197 9.36e-13

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 67.03  E-value: 9.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  35 YENKVYEENENLEYKCNNNFDKVFVTCNNG--SWSTKNMCiGKTNCKdPVTILNGYIKNKKDQYSFGDSVTYACKVNkle 112
Cdd:PHA02954  86 YDKPLYEVNSTITLICKDETKYFRCEEKNGntSWNDTVTC-PNAECQ-PLQLEHGSCQPVKEKYSFGEHITINCDVG--- 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484 113 kYSIVGNETVKCINKQWiPKYPVCKLiRCKYPALQNGFLNvfEKKFYYGDIVNFKCKKGFILLGSSVSTCdINSIWYPGI 192
Cdd:PHA02954 161 -YEVIGASYISCTANSW-NVIPSCQQ-KCDIPSLSNGLIS--GSTFSIGGVIHLSCKSGFTLTGSPSSTC-IDGKWNPVL 234


                 ....*
gi 146746484 193 PKCVK 197
Cdd:PHA02954 235 PICVR 239
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 144-196 1.43e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 1.43e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 146746484 144 PALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 144-195 3.75e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.15  E-value: 3.75e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 146746484   144 PALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 78-137 9.06e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.24  E-value: 9.06e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146746484  78 CKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSIVGNETVKCI-NKQWIPKYPVCK 137
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCN----EGYTLVGSSTITCTeNGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 78-136 2.22e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 2.22e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484    78 CKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSIVGNETVKCI-NKQWIPKYPVC 136
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCD----PGYTLIGSSTITCLeNGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
78-136 1.44e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.19  E-value: 1.44e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484   78 CKDPVTILNGYIKNKKDQYSFGDSVTYACKVNklekYSIVGNETVKCI-NKQWIPKYPVC 136
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPG----YRLVGSPTITCQeDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
141-195 8.01e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.88  E-value: 8.01e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 146746484  141 CKYP-ALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
Cdd:pfam00084   1 CPPPpDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 78-195 8.74e-05

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 43.10  E-value: 8.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146746484  78 CKDPVTILNGYIKNK-----KDQYSFGDSVTYACkvnkLEKY--SIVGNETVKCINKQWIpKYPVCKLIRCKYPA-LQNG 149
Cdd:PHA02927  21 CTIPSRPINMKFKNSvetdaNANYNIGDTIEYLC----LPGYrkQKMGPIYAKCTGTGWT-LFNQCIKRRCPSPRdIDNG 95

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 146746484 150 FLNVFEKKFyyGDIVNFKCKKGFILLGSSVSTCDINS----IWYPGIPKC 195
Cdd:PHA02927  96 QLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELGStgsmVWNPEAPIC 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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