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Conserved domains on  [gi|177539257|gb|ACB72985|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Liobagrus anguillicauda]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-195 3.21e-102

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00127:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 459  Bit Score: 302.26  E-value: 3.21e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00127 265 LALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMIAHGLTSSALFCLANTNYERTHSRTML 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00127 345 LARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTGLGTLITAGYSLYMFLMTQRGPLPDHI 424

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 177539257 161 INLQPYHTREHLLITLHLLPIILLIMKPEIMWGWW 195
Cdd:MTH00127 425 IALNPSHTREHLLMALHLLPLLLLILKPELIWGWT 459
 
Name Accession Description Interval E-value
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-195 3.21e-102

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 302.26  E-value: 3.21e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00127 265 LALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMIAHGLTSSALFCLANTNYERTHSRTML 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00127 345 LARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTGLGTLITAGYSLYMFLMTQRGPLPDHI 424

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 177539257 161 INLQPYHTREHLLITLHLLPIILLIMKPEIMWGWW 195
Cdd:MTH00127 425 IALNPSHTREHLLMALHLLPLLLLILKPELIWGWT 459
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-170 3.57e-40

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 142.14  E-value: 3.57e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:COG1008  281 LGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVSHGLITAALFLLVGVLYDRTHTRDIA 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:COG1008  361 DLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAALGLILTAAYLLWMYQRVFFGPLKEEL 440

                        170
                 ....*....|
gi 177539257 161 INLQPYHTRE 170
Cdd:COG1008  441 AELPDLNPRE 450
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-162 1.06e-34

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 127.36  E-value: 1.06e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257    1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:TIGR01972 275 LGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQMISHGLITAALFLLVGVLYERAHTRDIA 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:TIGR01972 355 KYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLAALGIVLAAAYMLTLYKRVFFGELSNPE 434


                  ..
gi 177539257  161 IN 162
Cdd:TIGR01972 435 VA 436
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-137 1.10e-33

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 121.27  E-value: 1.10e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257    1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLA-NTTYERTHSRTM 79
Cdd:pfam00361 153 LAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNI 232

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 177539257   80 ILVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGT 137
Cdd:pfam00361 233 RDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVG 290
 
Name Accession Description Interval E-value
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-195 3.21e-102

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 302.26  E-value: 3.21e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00127 265 LALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMIAHGLTSSALFCLANTNYERTHSRTML 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00127 345 LARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTGLGTLITAGYSLYMFLMTQRGPLPDHI 424

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 177539257 161 INLQPYHTREHLLITLHLLPIILLIMKPEIMWGWW 195
Cdd:MTH00127 425 IALNPSHTREHLLMALHLLPLLLLILKPELIWGWT 459
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-194 1.66e-101

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 300.29  E-value: 1.66e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00068 264 LALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALIQTPWSFSGAIILMISHGLTSSALFCLANTNYERTHSRTLL 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00068 344 LLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMVSLFNWSNWTILITGLGTLITAAYTLYMFLMTQRGPLPNHL 423

                        170       180       190
                 ....*....|....*....|....*....|....
gi 177539257 161 INLQPYHTREHLLITLHLLPIILLIMKPEIMWGW 194
Cdd:MTH00068 424 KTLFPTYTREHLLLALHILPMLLLILKPELISGM 457
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-194 4.51e-98

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 291.33  E-value: 4.51e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00124 264 LALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMIAHGLTSSMLFCLANTNYERTHSRTLL 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00124 344 LTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTGLATLITASYTLYMFLSTQRGTLPTHI 423

                        170       180       190
                 ....*....|....*....|....*....|....
gi 177539257 161 INLQPYHTREHLLITLHLLPIILLIMKPEIMWGW 194
Cdd:MTH00124 424 TTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-171 1.09e-88

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 267.53  E-value: 1.09e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00110 264 LSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMGATALMIAHGLTSSMLFCLANSNYERIHSRTMI 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00110 344 LARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIMSSFSWSNITIILMGLNMLITALYSLYMLITTQRGKLTHHI 423

                        170
                 ....*....|.
gi 177539257 161 INLQPYHTREH 171
Cdd:MTH00110 424 NNIKPSFTREN 434
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-191 9.49e-80

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 244.46  E-value: 9.49e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00206 260 LGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKGALLLMIAHGLVSSALFCLANLLYERSHTRTIL 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00206 340 GNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNFTLPLLGLGFLFTAIYSLYMFVMTQHGKTPNHL 419

                        170       180       190
                 ....*....|....*....|....*....|.
gi 177539257 161 INLQPYHTREHLLITLHLLPIILLIMKPEIM 191
Cdd:MTH00206 420 LSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 3-171 1.50e-70

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 221.00  E-value: 1.50e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   3 LWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILV 82
Cdd:MTH00044 268 CWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIFSGTNWGINGALILMIAHGLVSSALFCLANILYERSGTRTLSIT 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  83 RGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHIIN 162
Cdd:MTH00044 348 RGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLIISSIISWSILSFPIIGLATVFGAIYSLLIYQLTNSGSFPSWISN 427


                 ....*....
gi 177539257 163 LQPYHTREH 171
Cdd:MTH00044 428 VSPISSREH 436
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-160 1.44e-55

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 181.19  E-value: 1.44e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00150 223 LSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSNTSWGWVGALIMMVSHGFCSSGLFCLANYTYEKVHSRSLF 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00150 303 LSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIMIFPSLISYSPWFFVPLGLMVFLSGLYSLYLYTSIQHGGSSSFL 382
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-154 7.38e-54

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 177.27  E-value: 7.38e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00163 252 ISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMGSLLMMIGHGLCSSGLFCLANIIYERLGSRSLL 331

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRG 154
Cdd:MTH00163 332 INKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKLSMIFLMLLSFFSAAYSLYLYSYSQHG 405
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-194 6.98e-51

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 169.92  E-value: 6.98e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00014 258 ISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSNTSWGWQGALAMMIAHGLCSSALFALANMTYETTHTRSLF 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:MTH00014 338 LTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLSTAILLAITSFLAAAYSLFLYTSTQHGSPPSFM 417

                        170       180       190
                 ....*....|....*....|....*....|....
gi 177539257 161 INLQPYHTREHLLITLHLLPIILLIMKPEIMWGW 194
Cdd:MTH00014 418 NPLNLFTPRNHTLMTLHLVPLFILILKPDLITNW 451
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-154 4.28e-50

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 167.85  E-value: 4.28e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00205 256 ISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNGAIIMMVAHGLCSSGMFALANVNYERTNSRSML 335

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRG 154
Cdd:MTH00205 336 MNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKISGIPLSLISFLSGAYSLYLYSQSQHG 409
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-170 3.57e-40

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 142.14  E-value: 3.57e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:COG1008  281 LGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQMVSHGLITAALFLLVGVLYDRTHTRDIA 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:COG1008  361 DLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILAALGLILTAAYLLWMYQRVFFGPLKEEL 440

                        170
                 ....*....|
gi 177539257 161 INLQPYHTRE 170
Cdd:COG1008  441 AELPDLNPRE 450
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-162 1.06e-34

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 127.36  E-value: 1.06e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257    1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:TIGR01972 275 LGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQMISHGLITAALFLLVGVLYERAHTRDIA 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:TIGR01972 355 KYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLAALGIVLAAAYMLTLYKRVFFGELSNPE 434


                  ..
gi 177539257  161 IN 162
Cdd:TIGR01972 435 VA 436
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-170 1.40e-34

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 127.24  E-value: 1.40e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:PRK05846 283 LGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIFAGNQLGIQGAIFQMISHGLSSAALFLLVGVLYDRLHTRDIA 362

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHI 160
Cdd:PRK05846 363 DYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLILLGSFQVNPVIAFIATTGLILAAVYSLWLYQRVMFGPVKNEV 442

                        170
                 ....*....|
gi 177539257 161 INLQPYHTRE 170
Cdd:PRK05846 443 AKLKDLNGRE 452
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-137 1.10e-33

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 121.27  E-value: 1.10e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257    1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLA-NTTYERTHSRTM 79
Cdd:pfam00361 153 LAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNI 232

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 177539257   80 ILVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGT 137
Cdd:pfam00361 233 RDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVG 290
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-148 3.66e-32

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 120.55  E-value: 3.66e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00204 281 LSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLFTHTIEGLVAAVFLMLAHGFVSSALFIAVTFLYERHHTRLIK 360

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLF 148
Cdd:MTH00204 361 YYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSLLAAFEYSLGLGVLVTSGMVWSAAYSLYLY 428
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-148 1.33e-31

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 119.00  E-value: 1.33e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00217 278 LSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIFSHTIQGLVAAIFLMLAHGLVSSALFIAVTFLYERHHTRLIK 357

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLF 148
Cdd:MTH00217 358 YYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSLLAAFEYSYIVGVLASLGMVLSAGYSIYLY 425
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-147 3.71e-28

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 109.63  E-value: 3.71e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00226 302 MGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGSIFIMLAHGIVSSLLFILVTILYDRHHTRLIK 381

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYL 147
Cdd:MTH00226 382 YYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSILSSFNWNPIIGVFVCSGVILSAVYSFYF 448
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-152 4.38e-25

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 100.61  E-value: 4.38e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   2 ALWGVIMTgticLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMIL 81
Cdd:COG0651  283 MLVGALGA----LAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALAKALLFLAAGAIERATGTRDLDK 358

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 177539257  82 VRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGA-GTLITAAYSLYLFLMTQ 152
Cdd:COG0651  359 LGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLlSSLLTLAYFVRIFGRAQ 430
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 16-145 8.68e-23

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 94.71  E-value: 8.68e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  16 QTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQIIFPLTATW 95
Cdd:PRK12561 272 QDNVKRRLAYSSVSHMGFVLLGIAAFTDLGISGAMLQMISHGLIAAALFFLTGVTYERTHTLSIPNMGGLAKVMPKTFAL 351

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 177539257  96 WFISNLANLALPPLPNLMGELMI---ITTMFNWSPW----TLVLTGAGTLITAAYSL 145
Cdd:PRK12561 352 FTASSMASLALPGMSGFVSELTVflgITSSDVYSSTfrtiTILLAAVGLILTPIYLL 408
ndhD CHL00011
NADH dehydrogenase subunit 4
 6-145 6.15e-19

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 83.46  E-value: 6.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   6 VIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERThsRTMILVR-- 83
Cdd:CHL00011 288 IIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAILQIISHGFIGAALFFLAGTSYDRI--RLVYLDEmg 365

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 177539257  84 GLQIIFPLTATWWFISNLANLALPPLPNLMGELMI---ITTMFNWSPWT----LVLTGAGTLITAAYSL 145
Cdd:CHL00011 366 GIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIVffgIITSQKYLLMPkiliTFVMAIGMILTPIYLL 434
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 14-132 1.03e-18

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 83.06  E-value: 1.03e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  14 LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQIIFPLTA 93
Cdd:PRK06458 300 LRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHSLTKSAIFFASGNVLQKYGTRDINVIRGLLKVSPLTG 379

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 177539257  94 TWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVL 132
Cdd:PRK06458 380 WGLMLGALAIAGMPPFGVFISEFLILTAGLARGPLLIAI 418
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 16-145 1.04e-16

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 77.44  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  16 QTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQIIFPLTATW 95
Cdd:PRK02546 300 QRNLKRKIAYSSISHMGFVLIGIGSFTDLGTSGAMLQMISHGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAM 379

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 177539257  96 WFISNLANLALPPLPNLMGELMIITTMFNWSPWTL-------VLTGAGTLITAAYSL 145
Cdd:PRK02546 380 WTACSLASLALPGMSGFVAELMVFVGFATSDAYTLpfrvvvvFLAAVGVILTPIYLL 436
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 1-147 1.72e-16

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 76.48  E-value: 1.72e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00094 219 FSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGLMMMLAHGYTSTLMFYLIGEFYHISKSRLIY 298

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYL 147
Cdd:MTH00094 299 FMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSFFFIFFYFLVSFYYSLFL 365
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
1-165 5.42e-16

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 75.12  E-value: 5.42e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVI--MTGTIC-LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSR 77
Cdd:PRK06473 274 LATWAVVsvLYGASCaIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILAAVFQMISHGLISALLFLLVGVVYKKTGSR 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  78 TMILVRGL---QIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRG 154
Cdd:PRK06473 354 DVDVLRGLlnpERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGSFPIFPVQTLLCMIGTGLTAVYFLLLVNRVFFG 433

                        170
                 ....*....|.
gi 177539257 155 PLPQHIINLQP 165
Cdd:PRK06473 434 RLTAELSNLPR 444
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-148 1.24e-15

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 74.15  E-value: 1.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:PRK08375 277 LALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLHHALMKGALFLAAGAIEVTYGTRRLS 356

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFN-WSPWTLVLTGAGTLITAAYSLYLF 148
Cdd:PRK08375 357 ELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEaGQWLVLAVLLASSLLALLYFLRIW 425
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-145 1.37e-13

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 68.07  E-value: 1.37e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:PRK12667 301 LGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLLFLASGVFIHAAGTRDID 380

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGagtLITAAYSL 145
Cdd:PRK12667 381 ELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVL---LIASAISL 442
PRK12650 PRK12650
DUF4040 family protein;
7-149 3.41e-13

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 67.38  E-value: 3.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   7 IMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQ 86
Cdd:PRK12650 284 LMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRDIRRLGSLW 363

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 177539257  87 IIFPLTATWWFISNLANLALPPLPNLMGELMIITTMF-----NWSPWTLVLT-GAGTLITAAYSLYLFL 149
Cdd:PRK12650 364 RRMPFTFVSVTIAALSMAAVPPLFGFVSKEGMLTAFLeapggNAGVVLLLVGaALGAVFTFAYSARLVL 432
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 7-160 3.77e-13

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 67.10  E-value: 3.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   7 IMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQtpwGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQ 86
Cdd:COG1009  287 LFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG---AYVAALFHLLTHAFFKALLFLGAGSVIHATGTRDIRKMGGLR 363

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  87 IIFPLTATWWFISNLANLALPPLPNLMGELMIITTMF---NWSPWTLVLTGAGTLITAAYSLYLFLMT----QRGPLPQH 159
Cdd:COG1009  364 KKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALeagGLGPLLLAVALLGAFLTAFYSFRLFFLVffgkPRPKTPKH 443


                 .
gi 177539257 160 I 160
Cdd:COG1009  444 P 444
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 14-168 5.48e-11

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 60.54  E-value: 5.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  14 LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLA---NTTYERTHSRTMILVRGLQiifP 90
Cdd:PRK08676 292 LSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLVKSGLFFSAgilHRQYRSDRFDRIFDVFRLQ---P 368

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 177539257  91 LTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWtLVLTGAGTLITAAYSLYLFLMTQRGPLPQHIINLQPYHT 168
Cdd:PRK08676 369 VAAWGVILGSAAIIGMPPFPLFLSKFFILLQLGGISVW-LVLAVLLLLLLAASSFAIFLLKAFTRVSEGNADRPVFRT 445
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 7-138 2.50e-10

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 58.78  E-value: 2.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   7 IMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQ 86
Cdd:PRK12647 271 LTGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFLVAHSLYKGALFMVAGIIDHETGTRDITKLGGLR 350

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 177539257  87 IIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTL 138
Cdd:PRK12647 351 RAMPITAAAALLAALSMAGLPPLFGFLAKELIYEALLEAPLWSLILTVAAVL 402
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 1-147 2.98e-10

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 58.62  E-value: 2.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:PRK08377 279 MATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVDAGVFHMINHAIVKALLFLAVGYVGITLGGTEIE 358

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWS-PWTLVLTGAGTLITAAYSLYL 147
Cdd:PRK08377 359 KFEGLGKRMPLTALALTIGALSTVGIPLFNVFWSKFRIILAGLSAGyTWPVALVLGASVVEAVYYFRL 426
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 2-123 3.05e-10

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 58.59  E-value: 3.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   2 ALWGVIMTgticLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTG-----------ALVLMIAHGLVSSALFCLANTT 70
Cdd:PRK08667 281 ALLGVIYA----LKEHDLKGLLAYSSIENIGIILMGIGLYVIFGVYGldtlallalggALFHSLNHALFKSLLFLTAGSV 356

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 177539257  71 YERTHSRTMILVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMF 123
Cdd:PRK08667 357 VHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFASELLLYESFF 409
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
1-159 1.54e-09

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 56.26  E-value: 1.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWG---VIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSR 77
Cdd:PRK07363 274 LAIIGtisVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLLGAVAQMISHGLILALLFHLVGIVERKVGTR 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  78 T-------MILVRGLqiifPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAYSLYLFLM 150
Cdd:PRK07363 354 DldvlnglMNPIRGL----PLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFSTFPIPTLLCIVASGLTAVYFVILLNR 429


                 ....*....
gi 177539257 151 TQRGPLPQH 159
Cdd:PRK07363 430 TCFGRLDNK 438
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 16-146 1.62e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 56.13  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  16 QTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQIIFPLTATW 95
Cdd:PRK12665 294 QSDIKRLLSFTLVSHIGYMVFGIALSTVAGLSGAIYYVAHHITVQTTLFLVVGLIERQAGSSSLRRLGGLAKASPLLAVL 373

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 177539257  96 WFISNLaNLA-LPPLPNLMGELMIITTMFN---WSPWTLVltgAGTLITAAYSLY 146
Cdd:PRK12665 374 FFVPAL-NLGgIPPFSGFIGKVALLEAGAEdgtWLAWALV---AGGVVTSLLTLY 424
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-150 2.88e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 55.59  E-value: 2.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   2 ALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMIL 81
Cdd:PRK06589 287 PIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQVDK 366

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 177539257  82 VRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWS-PWTLVLTGAGTLITAAY-SLYLFLM 150
Cdd:PRK06589 367 LHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNqPWLSIIVMLVVIASSILsALYLLKI 437
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
1-119 1.46e-07

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 50.42  E-value: 1.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:PRK06277 272 LSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTSNLR 351

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMII 119
Cdd:PRK06277 352 KLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLA 390
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-145 2.03e-07

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 50.11  E-value: 2.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  14 LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALF-CLANTTYERTHSRTMILVRGLQIIFPLT 92
Cdd:COG1007  288 LAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFaVILLLSRKGGEAEEIEDLAGLARRSPLL 367

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 177539257  93 ATWWFISnLANLA-LPPLPNLMGELMIITTMFNWSPWTLVLTGA-GTLITAAYSL 145
Cdd:COG1007  368 ALAMTIF-LLSLAgIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVlNSVISAYYYL 421
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 7-118 2.84e-07

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 49.61  E-value: 2.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   7 IMTGTI-CLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGL 85
Cdd:PRK08668 283 IIVGTLmAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVIYRTGTTKISEMGGL 362

                         90       100       110
                 ....*....|....*....|....*....|...
gi 177539257  86 QIIFPLTATWWFISNLANLALPPLPNLMGELMI 118
Cdd:PRK08668 363 IEKMPFTFAMYLVAIISLAGIPPMSGFASKWLI 395
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 1-146 1.19e-06

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 48.00  E-value: 1.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:PRK12644 273 LGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLAMLLAHALFKAALFLVVGIIDHSTGTRDIR 352

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 177539257  81 LVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFN------WSPWTLVLTGAGTLITAAYSLY 146
Cdd:PRK12644 353 KLSGLGRRQPVLAVVAALAAASMAGLPPLLGFVAKEAALEAVLHdgalgpAGPVVLAGIVLGSILTVAYSLR 424
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-147 1.29e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 47.64  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   2 ALWGVImtgtICLRQTDLKSLIAYSSVSHMGLVAGGiliqtpwGLTGALvLMIAHGLVSSALFCLANTTYERTHS---RT 78
Cdd:PRK07234 256 ALLGVL----FALLEKDLKRMLAFSTISQLGFILAA-------PLVGGL-YALAHGLVKSTLFLCAGALPSRNFTeliSQ 323

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 177539257  79 MILVrglqiifpltATWWFISnLANLALPPLPNLMG---ELMIITTMFNWSPWTLVLTGAGTLITAAYSLYL 147
Cdd:PRK07234 324 MLGI----------GKWIPLT-MASFSIAGFPLLAGfvsKVLTLKNLLPWQAIALNLAAVGTAASFWKFIFL 384
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-64 1.62e-06

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 47.51  E-value: 1.62e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 177539257  14 LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALF 64
Cdd:PRK05777 289 LSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMTLGAF 339
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 11-150 2.43e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 47.01  E-value: 2.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  11 TICLRQTDLKSLIAYSSVSHMG---------LVAGGILIQTPWG---LTGALVLMIAHGLVSSALFCLANTTYERTHSRT 78
Cdd:PRK08376 303 AMAVVQKDVKRLLAYHSVSQIGymllglgvgLAALGDPAMASYGeiaLAGGIYHIVNHALYKALLFLTAGAVIYETGTRN 382

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 177539257  79 MILVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGT-LITAAYSLYLFLM 150
Cdd:PRK08376 383 LNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYESSALFNPILGVIAMIGSvLTLASFVKVFHTA 455
PRK12646 PRK12646
DUF4040 family protein;
14-167 2.58e-06

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 47.06  E-value: 2.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  14 LRQTDLKSLIAYSSVSHMGLVA-----GGILIQTPWG---------LTGALVLMIAHGLVSSALFCLANTTYERTHSRTM 79
Cdd:PRK12646 293 LKQWDLKGILAYSTISQLGMIMamvgiGGGYAQHQQDaiasiyvfvLFAALFHLMNHAIFKCALFMGVGIIDHEAGTRDI 372

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  80 ILVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFN---WSPWTLVLTGAGTLI-------TAAYSLYLFL 149
Cdd:PRK12646 373 RILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQtgqLSQFSLISMIIIVFIgviasifTFTYALYMVK 452

                        170
                 ....*....|....*...
gi 177539257 150 MTQRGPLPQHIINLQPYH 167
Cdd:PRK12646 453 EVFWGKYDSKVFTKKNIH 470
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 16-123 3.65e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 46.48  E-value: 3.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  16 QTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQIIFPLTATW 95
Cdd:PRK07691 296 YFDIKKIIIYNIMIAVGVILVGVAMMTESGMIGAIYYLIHDMIVKAALFLLIGIMIKITGTTDLKKMGGLIKRYPVLGWM 375

                         90       100
                 ....*....|....*....|....*...
gi 177539257  96 WFISNLANLALPPLPNLMGELMIITTMF 123
Cdd:PRK07691 376 FFIAALSLAGIPPLSGFYGKFFIVEGTF 403
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 14-109 5.45e-06

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 46.03  E-value: 5.45e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  14 LRQTDLKSLIAYSSVSHMGLV-----------AGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILV 82
Cdd:PRK06521 295 LAEHDLKRLLAYSTIENIGIIfvglglamvfiAYGMPLLAALALTAALYHLLNHALFKSLLFLGAGAVLHATGTRDMEKL 374

                         90       100
                 ....*....|....*....|....*..
gi 177539257  83 RGLQIIFPLTATWWFISNLANLALPPL 109
Cdd:PRK06521 375 GGLIRRMPWTAWAFLIGCLAISALPPL 401
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 16-138 1.24e-05

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 44.97  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  16 QTDLKSLIAYSSVSHMGLVAGGILIQ---TPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQIIFPLT 92
Cdd:PRK06525 293 QQDMKRLLAYSTITQLGYMFFGLSLAilgSRLALEGSIAYIFNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLV 372

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 177539257  93 ATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTL 138
Cdd:PRK06525 373 GVGFCVAALAITGVPPFNGFFSKFPIFAAGFELSVEYWILLPAMVL 418
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-67 1.32e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 44.72  E-value: 1.32e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLA 67
Cdd:PRK12662 285 LAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVS 351
ND5 MTH00209
NADH dehydrogenase subunit 5; Provisional
 7-166 1.65e-05

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177252 [Multi-domain]  Cd Length: 564  Bit Score: 44.64  E-value: 1.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   7 IMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPwglTGALVLMIAHGLVSSALF-CLANTTYERTHSRTMILVRGL 85
Cdd:MTH00209 251 LMASMSANVESDLKKIIALSTLSQLGLMMCSLGLNQP---ELAFFHLITHALFKALLFiCAGNIIHSHGHSQDIRMVGNL 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  86 QIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMF--NWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLPQHIINL 163
Cdd:MTH00209 328 WYQMPITSICLNIANLSLCGIPFLAGFYSKDLILESMLesNMPIMTLILMFLSTSLTAAYSMRLSYFSLWGPNSSKSLNS 407


                 ...
gi 177539257 164 QPY 166
Cdd:MTH00209 408 SFD 410
PRK12648 PRK12648
putative monovalent cation/H+ antiporter subunit A; Reviewed
 16-145 2.95e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237157 [Multi-domain]  Cd Length: 948  Bit Score: 44.03  E-value: 2.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  16 QTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQIIFPLTATW 95
Cdd:PRK12648 292 QHDLKGLLAYSTISHLGLITLLLGLGSPLAAVAAIFHIINHATFKASLFMAAGIIDHETGTRDMRRLSGLRRLMPITATL 371

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 177539257  96 WFISNLAnLALPPLPN--LMGELM----IITTMFNWSPWTL-VLTGAGTLITAAYSL 145
Cdd:PRK12648 372 AMVAAAA-MAGVPLLNgfLSKEMFfaetLDTHLLGSLDWLLpVAATLAGAFSVAYSL 427
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-163 1.75e-04

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 41.30  E-value: 1.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   1 LALWGVIMTGTICLRQTDLKSLIAYSSVSHMGLVAggiLIQTPWGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMI 80
Cdd:MTH00011 153 MAAMSALAGGLGGMNQTQLRPLLAYSSIGHMGWMT---MISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKI 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  81 LVRGlqiifPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSP--WTLVLTgAGTLITAAYslYLFLMTQRGPLPQ 158
Cdd:MTH00011 230 SSMS-----QTTSMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMilILLVLI-VGSLMNLFY--YLNLIFNFMYLSP 301


                 ....*
gi 177539257 159 HIINL 163
Cdd:MTH00011 302 TFSSL 306
PRK12645 PRK12645
monovalent cation/H+ antiporter subunit A; Reviewed
 15-155 2.47e-04

monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237155 [Multi-domain]  Cd Length: 800  Bit Score: 41.06  E-value: 2.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  15 RQTDLKSLIAYSSVSHMGLV-----AGGILIQTPWG--------LTGALVLMIAHGLVSSALFCLANTTYERTHSRTMIL 81
Cdd:PRK12645 294 KQTDLKGILAFSTVSQLGLImsllgIGAASLHYQGDdskiyaaaITAAIFHLINHATFKGSLFMIVGIVDHETGTRDIRK 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  82 VRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTM--------FNWSPWTL---VLTGAGTLITAAYSLYLFLM 150
Cdd:PRK12645 374 LGGLMTIMPITFTIALIGALSMAGLPPFNGFLSKEMFFESMlnateanlFSLDTWGVlfpVIAWVASVFTFVYSIIFIFK 453


                 ....*
gi 177539257 151 TQRGP 155
Cdd:PRK12645 454 TFFGK 458
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-143 3.18e-04

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 40.70  E-value: 3.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   14 LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALF-CLANT-TYERTHSRTMILVRGLQIIFPL 91
Cdd:TIGR01770 288 LAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMSLGAFgVLSLLrSYKDEWIEYISDFAGLFKTNPI 367

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 177539257   92 TATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVLTGAGTLITAAY 143
Cdd:TIGR01770 368 LAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAF 419
PRK08042 PRK08042
formate hydrogenlyase subunit 3; Reviewed
 10-124 4.66e-04

formate hydrogenlyase subunit 3; Reviewed


Pssm-ID: 181206 [Multi-domain]  Cd Length: 593  Bit Score: 40.20  E-value: 4.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  10 GTICLRQTDLKSLIAYSSVSHMGLV-----AG--GILIQTP----WGLTGALVLMIAHGLVSSALFCLANTTYERTHSRT 78
Cdd:PRK08042 260 GLYALMEHNIQRLLAYHTLENIGIIllglgAGvtGIALEQPaliaLGLVGGLYHLLNHSLFKSVLFLGAGSVWFRTGHRD 339

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 177539257  79 MILVRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFN 124
Cdd:PRK08042 340 IEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEWVIYQSFFK 385
PRK07390 PRK07390
NAD(P)H-quinone oxidoreductase subunit F; Validated
 7-132 3.04e-03

NAD(P)H-quinone oxidoreductase subunit F; Validated


Pssm-ID: 236008 [Multi-domain]  Cd Length: 613  Bit Score: 37.58  E-value: 3.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   7 IMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPwglTGALVLMIAHGLVSSALFCLANTTYERTHSRTMILVRGLQ 86
Cdd:PRK07390 296 IGASLVAIAQIDIKRALSYSTSAYLGLVFIAVGLQQP---DIALLLLLTHAIAKALLFMSVGSIILTTITQDLTELGGLW 372

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 177539257  87 IIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLVL 132
Cdd:PRK07390 373 SRMPATTLAFLVGSAGLVALLPLGGFWALLRLADGLWAVSPWLVGV 418
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 2-150 4.04e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 37.17  E-value: 4.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   2 ALWGVIMTgticLRQTDLKSLIAYSSVSHMGLVAGGILiqtpWGLTGALVLMIAHGLVSSALFCLANttYERTHSRTMIL 81
Cdd:MTH00144 155 ALVGSIGG----LNQTQVRALLAYSSISHTGWMLVAIL----HGSWLMWMYFLIYIVSSGFLFFSLW--SGDSGSMKDLG 224

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 177539257  82 VRGLQIIFPLTATWWFISnlanLA-LPPLPNLMGELMIITTMFNWSPWTLVLTG-AGTLITAAYSLYLFLM 150
Cdd:MTH00144 225 SLKPSYKTGLSIISLLLS----LGgLPPFLGFCSKLLVLISSMESSPLLLILLLlLGSLISLFFYLSVFFS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 7-64 5.88e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 36.55  E-value: 5.88e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 177539257   7 IMTGTI-CLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGLTGALVLMIAHGLVSSALF 64
Cdd:MTH00196 163 LFVGAIgALNQTKIKRLLAYSGIGHMGFVLWGIEIGSFESIQASLVYLFIYIIMSICVF 221
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 6-147 6.42e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 36.73  E-value: 6.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   6 VIMTGTICLRQTDLKSLIAYSSVS---HMGLVAGGILIQTP-WGLTGALVLMIAHGLVSSALFCLANTTYERTHSRTMIL 81
Cdd:PRK12649 289 MVLAGFLAFRQTDIKAILAYSTISqlaYLMTMYGYTTYHEPgLGVAAATFHLLNHATFKACLFLVAGIVAHEAATRDIRK 368

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 177539257  82 VRGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWS-----PWTLVLTG---AGTLITAAYSLYL 147
Cdd:PRK12649 369 LGGLRKEMPITFIVASIAALAMAGIPPLNGFLSKEMFYETSVEMGaliggPFTIIIPAvavLGGVFTFAYSIKL 442
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 7-167 7.98e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 36.67  E-value: 7.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   7 IMTGTICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPwglTGALVLMIAHGLVSSALF-CLANTTYERTHSRTMILVRGL 85
Cdd:MTH00207 255 LMAGLSAMTECDMKKIIALSTLSQLGVMMASLGLGMP---KLALFHLITHALFKALLFvCAGSLIHSHHHSQDLRTMGNL 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257  86 QIIFPLTATWWFISNLANLALPPLPNLMGELMII--TTMFNWSPWTLVLTGAGTLITAAYSLYLFLMTQRGPLpqhiiNL 163
Cdd:MTH00207 332 TNQMPLTTSCLLIANLALCGSPFLSGFYSKDLILesSLFYPHNSLMILMIFLATALTAAYSTRFTLAVLWSPN-----SS 406


                 ....
gi 177539257 164 QPYH 167
Cdd:MTH00207 407 SPYH 410
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 6-151 9.32e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 36.21  E-value: 9.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 177539257   6 VIMTGTICLRQTDLKSLIAYSSVSHMG--LVAGGIliqtpWGLTGALVLMIAHGLVSSALFCLANTT-YERTHSRTMILV 82
Cdd:MTH00020 285 VFFAATVGLVQNDLKKVIAYSTCSQLGymVVACGL-----SHYSISLFHLMNHAFFKALLFLSAGSViHALSDEQDMRKM 359

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 177539257  83 RGLQIIFPLTATWWFISNLANLALPPLPNLMGELMIITTMFNWSPWTLV--LTGAGTLITAAYSLYLFLMT 151
Cdd:MTH00020 360 GGLISFLPLTYIFFLIGSLSLMGFPYLTGFYSKDLILELAFGQYYLIFAywLGCFSALLTAFYSIRLIYLT 430
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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